metoprolol and oxprenolol

metoprolol has been researched along with oxprenolol in 109 studies

Research

Studies (109)

TimeframeStudies, this research(%)All Research%
pre-199068 (62.39)18.7374
1990's14 (12.84)18.2507
2000's17 (15.60)29.6817
2010's8 (7.34)24.3611
2020's2 (1.83)2.80

Authors

AuthorsStudies
Carrupt, PA; Gaillard, P; Schambel, P; Testa, B1
Artursson, P; Beigi, F; Lundahl, P; Luthman, K; Palm, K; Strandlund, G; Ungell, AL1
Ghuloum, AM; Jain, AN; Sage, CR1
Danelian, E; Hämäläinen, MD; Hansson, A; Karlén, A; Karlsson, R; Lennernäs, H; Löfâs, S; Winiwarter, S1
Topliss, JG; Yoshida, F1
Bleasby, K; Brown, CD; Dudley, AJ1
Ertl, P; Rohde, B; Selzer, P1
Artursson, P; Luthman, K; Norinder, U; Stenberg, P1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Caron, G; Ermondi, G1
Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R1
Abraham, MH; Acree, WE; Ibrahim, A1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Carrupt, PA; Guillarme, D; Henchoz, Y; Rudaz, S; Veuthey, JL1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Bard, B; Carrupt, PA; Martel, S1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Antonsson, M; Bengtsson, O; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Jerndal, G; Wan, H; Winiwarter, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Akamatsu, M1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Bellman, K; Knegtel, RM; Settimo, L1
Levy, JV1
Meier, J1
Erdmann, E; Krawietz, W; Pruchniewski, M; Weinsteiger, M1
Kiechel, JR; Meier, J1
Gioffrè, PA; Motolese, M; Nigri, A; Reale, A1
Bellucci, R; Bonomi, L; Massa, F; Noya, E; Perfetti, S1
Al-Zaibak, M; Anderson, EG; Calcraft, B; Jariwalla, AG1
Tuomilehto, J1
Nissinen, A; Tuomilehto, J1
Clancy, A; Nicholson, AN; Wright, CM1
Mutschler, E; Schäfer, M1
Davidson, C; Singleton, W; Taylor, SH; Thadani, U2
Dawes, CP; John, VA; Kendall, MJ1
Ghani, P; Lopatin, IuM; Mareev, VIu; Sinitsin, VE1
Allavena, A; Brambilla, G; Gazzaniga, GM; Martelli, A; Mazzei, M; Robbiano, L1
Hughson, RL; Klein, CS; Kowalchuk, JM1
Enquist, M; Hermansson, J1
Fujiyama, K; Hoshino, T; Ikeda, T; Mashiba, H; Takeuchi, T; Tanaka, Y; Tominaga, M1
Jonkers, R; Koopmans, RP; Oosterhuis, B; van Boxtel, CJ1
Hughson, RL1
Akritopoulos, P; Petounis, AD1
Jackson, PR; Lewis, RV; Ramsay, LE2
Kawecka-Jaszcz, K; Skoczeń, M1
Cruickshank, JM; Neil-Dwyer, G1
Hawksworth, GM; Petrie, JC; Rigby, JW; Scott, AK1
Cybulska, I; Niegowska, J; Sznajderman, M; Zawadzki, Z1
Fishbein, L; Jackson, CD1
Halawa, B; Mazurek, W1
Antonaccio, MJ; DeForrest, JM; High, J; Sybertz, E1
Belpaire, FM; Bogaert, MG; Mugabo, P; Rosseel, MT1
Dal Negro, RW; Pomari, C; Trevisan, F; Turco, P; Zoccatelli, O1
Alexopoulos, D; Cobbe, SM; Manley, BS; Robinson, GJ1
al-Gohary, O; Lyal, J; Murray, JB1
Mutschler, E; Pflugmann, G; Spahn, H1
Hirtz, J1
John, VA; Moppert, J; Shotton, PA; Theobald, W1
Ayer, A; Guittard, G; Khanna, S; Swanson, DR; Theeuwes, F1
Fara, JW; Myrback, RE; Swanson, DR1
Jutrin, I; Lang, R; Ravid, M1
Asano, Y; Hosoda, S; Kusano, E; Takeda, K1
Bloom, SR; Keen, H; Viberti, GC2
Bishop, H; Kendall, MJ; Quarterman, CP; Schneider, RE1
Hampton, JR; Wilcox, RG1
Coltart, DJ; Hearse, DJ; Manning, AS; Yellon, DM1
Lee, PS; Silke, B; Taylor, SH1
Brotelle, R; Colot, M; de Clavière, M; Heyndrickx, JP1
Lochan, R; Silke, B; Taylor, SH1
Day, JL; Metcalfe, J; Simpson, CN1
Alvares, RF; Goodwin, JF1
Amery, A; Bulpitt, C; Cattaert, A; Fagard, R; Staessen, J; Vanhees, L1
Hilal, A; Lee, PS; Silke, B; Taylor, SH1
Hatori, Y; Horii, M; Nakamura, Y; Nemoto, E; Otsuka, K; Sakai, T; Tsukiyama, H; Yamamoto, Y; Yamato, T; Yoshii, Y1
Auzépy, P; Boukara, N; Giudicelli, JF; Richard, C1
Ostman, J1
Weisswange, A1
Sandström, B1
Jack, DB; Kendall, MJ; Quarterman, CP; Smith, SR; Zaman, R1
Chung, DC; Laschuk, MJ1
Friedewald, WT; Frishman, WH; Furberg, CD1
Dow, RJ; Fee, WM1
Shanks, RG1
Ferrara, LA; Mancini, M; Marotta, T; Mastranzo, P; Scilla, A; Strazzullo, P1
Braakhekke, J; Folgering, H1
Jenkins, RM; Nagle, RE1
Leroux, F; Sandrenan, N; Sioufi, A1
Besterman, EM; Comerford, MB1
Caimi, G; Capobianco, D; Catania, A; Francavilla, G; Frazzetta, F; Sarno, A1
Mehta, AC1
Balasubramanian, V; Mann, S; Millar-Craig, MW; Raftery, EB1
Badia, A; Vila, E1
Hartonen, K; Riekkola, ML1
Fraudeau, C; Luck, G; Mangani, F; Vérette, E1
Caldwell, GW; Evangelisto, M; Masucci, JA; White, R1
Caldwell, GW; Demarest, K; Easlick, SM; Gunnet, J; Masucci, JA1
Hedeland, M; Isaksson, R; Jönsson, S; Pettersson, C1
Banga, AK; Betageri, GV; Chaturvedula, A; Conjeevaram, R; Sunkara, G1
D'Orazio, G; Fanali, S1
Mizogami, M; Takakura, K; Tsuchiya, H1
Jiang, X; Sun, N; Xi, Y; Zhang, Y1
Esler, M; Grassi, G; Kjeldsen, SE; Kreutz, R; Mancia, G; Pathak, A1
Chen, YW; Chou, AK1

Reviews

10 review(s) available for metoprolol and oxprenolol

ArticleYear
[Comparative pharmacokinetics of beta-blockers].
    La Nouvelle presse medicale, 1978, Sep-20, Volume: 7, Issue:31

    Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Half-Life; Humans; Metoprolol; Oxprenolol; Pindolol; Practolol; Propranolol; Sotalol; Timolol

1978
[Beta-blockaders in the treatment of hypertension in pregnancy].
    Kardiologia polska, 1985, Volume: 28, Issue:5

    Topics: Adrenergic beta-Antagonists; Atenolol; Drug Evaluation; Female; Humans; Hypertension; Metoprolol; Oxprenolol; Pindolol; Pregnancy; Pregnancy Complications, Cardiovascular; Propranolol

1985
A toxicological review of beta-adrenergic blockers.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1986, Volume: 6, Issue:3

    Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Cocarcinogenesis; Ethanolamines; Female; Kinetics; Labetalol; Lethal Dose 50; Male; Metoprolol; Mice; Mutagens; Nadolol; Neoplasms, Experimental; Oxprenolol; Pindolol; Practolol; Propanolamines; Propranolol; Rats; Sotalol; Timolol

1986
[Effect of beta-adrenolytic drugs on the survival of patients after myocardial infarction].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1986, Jan-01, Volume: 39, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Aftercare; Aged; Clinical Trials as Topic; Follow-Up Studies; Humans; Metoprolol; Middle Aged; Myocardial Infarction; Oxprenolol; Propranolol; Time Factors; Timolol

1986
The gastrointestinal absorption of drugs in man: a review of current concepts and methods of investigation.
    British journal of clinical pharmacology, 1985, Volume: 19 Suppl 2

    Topics: Body Water; Gastric Emptying; Humans; Intestinal Absorption; Kinetics; Metoprolol; Oxprenolol; Pharmaceutical Preparations

1985
beta-adrenergic blockade and diabetes mellitus. A review.
    Acta medica Scandinavica. Supplementum, 1983, Volume: 672

    Topics: Adrenergic beta-Antagonists; Alprenolol; Blood Glucose; Catecholamines; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Drug Synergism; Fatty Acids, Nonesterified; Gluconeogenesis; Glucose Tolerance Test; Glycerol; Glycogen; Humans; Hypertension; Hypoglycemia; Insulin; Lactates; Lactic Acid; Metoprolol; Oxprenolol; Propranolol

1983
The new beta-adrenergic antagonists.
    Canadian Anaesthetists' Society journal, 1984, Volume: 31, Issue:4

    Topics: Adrenergic beta-Antagonists; Atenolol; Humans; Labetalol; Metoprolol; Nadolol; Oxprenolol; Pindolol; Propanolamines; Timolol

1984
The use of beta-adrenergic blocking drugs in patients with myocardial infarction.
    Current problems in cardiology, 1984, Volume: 9, Issue:3

    Topics: Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Atenolol; Clinical Trials as Topic; Humans; Hypertension; Metoprolol; Myocardial Infarction; Oxprenolol; Pindolol; Practolol; Propranolol; Receptors, Adrenergic, beta; Risk; Sotalol; Timolol

1984
Comparative efficacy of β-blockers on mortality and cardiovascular outcomes in patients with hypertension: a systematic review and network meta-analysis.
    Journal of the American Society of Hypertension : JASH, 2017, Volume: 11, Issue:7

    Topics: Adrenergic beta-Antagonists; Age Factors; Antihypertensive Agents; Atenolol; Coronary Disease; Humans; Hydrophobic and Hydrophilic Interactions; Hypertension; Incidence; Metoprolol; Network Meta-Analysis; Oxprenolol; Propranolol; Stroke; Treatment Outcome

2017
Diverse pharmacological properties, trial results, comorbidity prescribing and neural pathophysiology suggest European hypertension guideline downgrading of beta-blockers is not justified.
    Blood pressure, 2022, Volume: 31, Issue:1

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Atenolol; Cardiovascular Diseases; Comorbidity; Heart Failure; Humans; Hypertension; Metoprolol; Oxprenolol; Propranolol

2022

Trials

26 trial(s) available for metoprolol and oxprenolol

ArticleYear
Acute influence of different beta-blocking agents upon left heart hemodynamics at rest and during exercise in patients with coronary artery disease.
    European journal of cardiology, 1979, Volume: 9, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Coronary Disease; Exercise Test; Female; Hemodynamics; Humans; Male; Metoprolol; Middle Aged; Oxprenolol; Propanolamines

1979
A comparison between metroprolol, alprenolol and oxprenolol in the treatment of hypertension.
    Acta medica Scandinavica. Supplementum, 1979, Volume: 625

    Topics: Alprenolol; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Drug Evaluation; Follow-Up Studies; Humans; Hypertension; Metoprolol; Oxprenolol; Placebos; Propanolamines; Time Factors

1979
Double-blind comparison of metoprolol, alprenolol, and oxprenolol in hypertension.
    European journal of clinical pharmacology, 1979, Volume: 16, Issue:6

    Topics: Adult; Aged; Alprenolol; Blood Pressure; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Male; Metoprolol; Middle Aged; Oxprenolol; Propanolamines

1979
Comparison of the immediate effects of five beta-adrenoreceptor-blocking drugs with different ancillary properties in angina pectoris.
    The New England journal of medicine, 1979, Apr-05, Volume: 300, Issue:14

    Topics: Adult; Angina Pectoris; Blood Pressure; Dose-Response Relationship, Drug; Drug Evaluation; Electrocardiography; Exercise Test; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Oxprenolol; Practolol; Propanolamines; Propranolol

1979
Comparison of plasma and saliva levels of metoprolol and oxprenolol.
    British journal of clinical pharmacology, 1978, Volume: 5, Issue:3

    Topics: Adolescent; Adult; Amylases; Humans; Male; Metoprolol; Oxprenolol; Propanolamines; Saliva; Salivary Proteins and Peptides; Salivation; Time Factors

1978
[Potential possibilities of using adrenergic beta blockers in chronic heart failure].
    Kardiologiia, 1992, Volume: 32, Issue:3

    Topics: Adolescent; Adult; Aged; Chronic Disease; Female; Heart Failure; Hemodynamics; Humans; Male; Metoprolol; Middle Aged; Oxprenolol; Prognosis; Propranolol

1992
A nonsteady-state agonist antagonist interaction model using plasma potassium concentrations to quantify the beta-2 selectivity of beta blockers.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 249, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Female; Humans; Male; Metoprolol; Models, Biological; Oxprenolol; Potassium; Receptors, Adrenergic, beta; Terbutaline

1989
Ramp work tests with three different beta-blockers in normal human subjects.
    European journal of applied physiology and occupational physiology, 1989, Volume: 58, Issue:7

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Heart Rate; Humans; Lactates; Male; Metoprolol; Oxprenolol; Oxygen Consumption; Physical Exertion; Propranolol

1989
[Effect of beta-adrenolytic drugs on the survival of patients after myocardial infarction].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1986, Jan-01, Volume: 39, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Aftercare; Aged; Clinical Trials as Topic; Follow-Up Studies; Humans; Metoprolol; Middle Aged; Myocardial Infarction; Oxprenolol; Propranolol; Time Factors; Timolol

1986
Respiratory effects of four adrenergic blocking agents combined with a diuretic in treating hypertension with concurrent chronic obstructive lung disease.
    International journal of clinical pharmacology research, 1986, Volume: 6, Issue:4

    Topics: Adrenergic beta-Antagonists; Airway Resistance; Atenolol; Chlorthalidone; Drug Therapy, Combination; Forced Expiratory Volume; Humans; Hypertension; Labetalol; Lung Diseases, Obstructive; Male; Maximal Midexpiratory Flow Rate; Metoprolol; Oxprenolol; Random Allocation

1986
The relative antihypertensive potency of propranolol, oxprenolol, atenolol, and metoprolol given once daily. A double-blind, crossover, placebo-controlled study in ambulatory patients.
    Archives of internal medicine, 1985, Volume: 145, Issue:7

    Topics: Adult; Aged; Analysis of Variance; Atenolol; Blood Pressure; Body Weight; Delayed-Action Preparations; Double-Blind Method; Drug Evaluation; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Oxprenolol; Physical Exertion; Propranolol; Prospective Studies; Pulse

1985
Comparison of five beta-adrenoreceptor antagonists with different ancillary properties during sustained twice daily therapy in angina pectoris.
    The American journal of medicine, 1980, Volume: 68, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Angina Pectoris; Blood Pressure; Double-Blind Method; Exercise Test; Female; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Oxprenolol; Physical Exertion; Placebos; Practolol; Propanolamines; Propranolol; Time Factors

1980
Beta blockade and diabetes mellitus: effect of oxprenolol and metoprolol on the metabolic, cardiovascular, and hormonal response to insulin-induced hypoglycemia in normal subjects.
    Metabolism: clinical and experimental, 1980, Volume: 29, Issue:9

    Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Diabetes Mellitus; Fatty Acids, Nonesterified; Female; Glucagon; Humans; Hydrocortisone; Hypoglycemia; Insulin; Kinetics; Male; Metoprolol; Middle Aged; Oxprenolol; Propanolamines; Pulse

1980
Beta blockade and diabetes mellitus: effect of oxprenolol and metoprolol on the metabolic, cardiovascular, and hormonal response to insulin-induced hypoglycemia in insulin-dependent diabetics.
    Metabolism: clinical and experimental, 1980, Volume: 29, Issue:9

    Topics: Adrenergic beta-Antagonists; Adult; Blood Glucose; Blood Pressure; Diabetes Mellitus; Fatty Acids, Nonesterified; Female; Glucagon; Humans; Hydrocortisone; Hypoglycemia; Insulin; Kinetics; Male; Metoprolol; Middle Aged; Oxprenolol; Propanolamines; Pulse

1980
Comparative study of atenolol, metoprolol, metoprolol durules, and slow-release oxprenolol in essential hypertension.
    British heart journal, 1981, Volume: 46, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Blood Pressure; Clinical Trials as Topic; Delayed-Action Preparations; Female; Heart Rate; Humans; Hypertension; Male; Metoprolol; Middle Aged; Oxprenolol; Physical Exertion; Random Allocation

1981
Intravenous beta-blockade in coronary heart disease: is cardioselectivity or intrinsic sympathomimetic activity hemodynamically useful?
    The New England journal of medicine, 1982, Mar-18, Volume: 306, Issue:11

    Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Clinical Trials as Topic; Coronary Disease; Heart; Heart Rate; Heart Ventricles; Hemodynamics; Humans; Metoprolol; Middle Aged; Oxprenolol; Practolol; Propranolol; Random Allocation; Sympathetic Nervous System; Vascular Resistance

1982
Speed of onset of pharmacodynamic activity of propranolol, practolol, oxprenolol and metoprolol after intravenous infection in man.
    British journal of clinical pharmacology, 1981, Volume: 12, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Female; Heart Rate; Humans; Injections, Intravenous; Male; Metoprolol; Middle Aged; Oxprenolol; Practolol; Propranolol; Time Factors

1981
Adrenergic mechanisms in control of plasma lipid concentrations.
    British medical journal (Clinical research ed.), 1982, Apr-17, Volume: 284, Issue:6323

    Topics: Adrenergic beta-Antagonists; Atenolol; Cholesterol; Cholesterol, HDL; Clinical Trials as Topic; Fatty Acids, Nonesterified; Female; Humans; Hypertension; Lipids; Lipoproteins, HDL; Lipoproteins, VLDL; Male; Metoprolol; Oxprenolol; Propranolol; Random Allocation; Triglycerides

1982
Secondary prevention with beta-adrenoceptor blockers in post-myocardial infarction patients.
    American heart journal, 1982, Volume: 104, Issue:6

    Topics: Adrenergic beta-Antagonists; Clinical Trials as Topic; Double-Blind Method; Humans; Metoprolol; Myocardial Infarction; Oxprenolol; Practolol; Propranolol; Recurrence; Sotalol; Timolol

1982
[Improved prognosis using beta blockers after myocardial infarct?].
    Lebensversicherungs Medizin, 1984, Jan-01, Volume: 36, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Clinical Trials as Topic; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Oxprenolol; Prognosis; Propranolol; Sotalol; Timolol

1984
The use of beta-adrenergic blocking drugs in patients with myocardial infarction.
    Current problems in cardiology, 1984, Volume: 9, Issue:3

    Topics: Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Atenolol; Clinical Trials as Topic; Humans; Hypertension; Metoprolol; Myocardial Infarction; Oxprenolol; Pindolol; Practolol; Propranolol; Receptors, Adrenergic, beta; Risk; Sotalol; Timolol

1984
Use of beta-blocking agents with group therapy in a smoking withdrawal clinic.
    Journal of the Royal Society of Medicine, 1984, Volume: 77, Issue:8

    Topics: Adult; Clinical Trials as Topic; Combined Modality Therapy; Double-Blind Method; Female; Humans; Male; Metoprolol; Middle Aged; Oxprenolol; Psychotherapy, Group; Smoking; Substance Withdrawal Syndrome

1984
Effect of oxprenolol and metoprolol on serum lipid concentration.
    European journal of clinical pharmacology, 1984, Volume: 26, Issue:3

    Topics: Adult; Blood Pressure; Cholesterol; Female; Heart Rate; Humans; Lipids; Male; Metoprolol; Middle Aged; Oxprenolol; Triglycerides

1984
The symptomatic and objective effects of nifedipine in combination with beta-blocker therapy in severe angina pectoris.
    Postgraduate medical journal, 1982, Volume: 58, Issue:685

    Topics: Adult; Angina Pectoris; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Humans; Male; Metoprolol; Middle Aged; Nifedipine; Nitroglycerin; Oxprenolol; Propanolamines; Pyridines

1982
A comparison of the effects of the slow release formulations of metoprolol and oxprenolol in hypertension.
    Annals of clinical research, 1982, Volume: 14, Issue:1

    Topics: Adult; Delayed-Action Preparations; Female; Heart Rate; Humans; Hypertension; Male; Metoprolol; Middle Aged; Oxprenolol; Propanolamines; Systole; Time Factors

1982
Detection of beta-blockers in urine by solid-phase extraction-supercritical fluid extraction and gas chromatography-mass spectrometry.
    Journal of chromatography. B, Biomedical applications, 1996, Feb-09, Volume: 676, Issue:1

    Topics: Acetic Anhydrides; Acetylation; Adrenergic beta-Antagonists; Adult; Gas Chromatography-Mass Spectrometry; Humans; Hydrogen-Ion Concentration; Indicators and Reagents; Metoprolol; Oxprenolol; Propranolol; Pyridines

1996

Other Studies

75 other study(ies) available for metoprolol and oxprenolol

ArticleYear
Binding of arylpiperazines, (aryloxy)propanolamines, and tetrahydropyridylindoles to the 5-HT1A receptor: contribution of the molecular lipophilicity potential to three-dimensional quantitative structure-affinity relationship models.
    Journal of medicinal chemistry, 1996, Jan-05, Volume: 39, Issue:1

    Topics: Indoles; Ligands; Models, Molecular; Molecular Conformation; Molecular Structure; Piperazines; Propanolamines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Structure-Activity Relationship; Tetrahydronaphthalenes

1996
Evaluation of dynamic polar molecular surface area as predictor of drug absorption: comparison with other computational and experimental predictors.
    Journal of medicinal chemistry, 1998, Dec-31, Volume: 41, Issue:27

    Topics: Adrenergic beta-Antagonists; Amides; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Drug Design; Epithelial Cells; Formamides; Humans; Intestinal Absorption; Liposomes; Models, Molecular; Molecular Conformation; Monte Carlo Method; Permeability; Propanolamines; Structure-Activity Relationship

1998
Molecular hashkeys: a novel method for molecular characterization and its application for predicting important pharmaceutical properties of molecules.
    Journal of medicinal chemistry, 1999, May-20, Volume: 42, Issue:10

    Topics: Drug Design; Intestinal Absorption; Models, Molecular; Pharmaceutical Preparations; Structure-Activity Relationship

1999
SPR biosensor studies of the direct interaction between 27 drugs and a liposome surface: correlation with fraction absorbed in humans.
    Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11

    Topics: Humans; Intestinal Absorption; Liposomes; Pharmaceutical Preparations; Pharmacokinetics; Predictive Value of Tests; Surface Plasmon Resonance

2000
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
The organic cation transporter OCT2 mediates the uptake of beta-adrenoceptor antagonists across the apical membrane of renal LLC-PK(1) cell monolayers.
    British journal of pharmacology, 2000, Volume: 131, Issue:1

    Topics: Adrenergic beta-Antagonists; Biological Transport; Carrier Proteins; Cells, Cultured; Cimetidine; Hydrogen-Ion Concentration; Kidney; Metoprolol; Organic Cation Transport Proteins; Organic Cation Transporter 2; Propranolol; Quinolines

2000
Fast calculation of molecular polar surface area as a sum of fragment-based contributions and its application to the prediction of drug transport properties.
    Journal of medicinal chemistry, 2000, Oct-05, Volume: 43, Issue:20

    Topics: Biological Availability; Biological Transport; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Reproducibility of Results

2000
Experimental and computational screening models for the prediction of intestinal drug absorption.
    Journal of medicinal chemistry, 2001, Jun-07, Volume: 44, Issue:12

    Topics: Biological Transport; Carbon Radioisotopes; Cell Line; Cell Membrane; Cell Membrane Permeability; Ciprofloxacin; Computational Biology; Drug Design; Foscarnet; Humans; Hydrogen Bonding; Intestinal Absorption; Intestinal Mucosa; Lactulose; Mannitol; Models, Biological; Raffinose; Surface Properties; Tritium; Verapamil

2001
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
QSAR study on permeability of hydrophobic compounds with artificial membranes.
    Bioorganic & medicinal chemistry, 2007, Jun-01, Volume: 15, Issue:11

    Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship

2007
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:3

    Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization

2008
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
High-throughput log P determination by ultraperformance liquid chromatography: a convenient tool for medicinal chemists.
    Journal of medicinal chemistry, 2008, Feb-14, Volume: 51, Issue:3

    Topics: Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Chromatography, Liquid; Mathematics; Pharmaceutical Preparations; Software

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Lipophilicity of basic drugs measured by hydrophilic interaction chromatography.
    Journal of medicinal chemistry, 2009, May-28, Volume: 52, Issue:10

    Topics: Chemistry, Pharmaceutical; Chromatography; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Pharmaceutical Preparations; Solubility; Technology, Pharmaceutical

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Structure-brain exposure relationships in rat and human using a novel data set of unbound drug concentrations in brain interstitial and cerebrospinal fluids.
    Journal of medicinal chemistry, 2009, Oct-22, Volume: 52, Issue:20

    Topics: Animals; Blood-Brain Barrier; Brain; Extracellular Fluid; Humans; Linear Models; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Importance of physicochemical properties for the design of new pesticides.
    Journal of agricultural and food chemistry, 2011, Apr-13, Volume: 59, Issue:7

    Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic

2011
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Beta-adrenergic receptor blocking drugs in spontaneous hypertension.
    The American journal of medicine, 1976, Volume: 61, Issue:5

    Topics: Adrenergic beta-Antagonists; Aging; Alprenolol; Animals; Blood Pressure; Hypertension; Male; Metoprolol; Oxprenolol; Pindolol; Practolol; Propanolamines; Propranolol; Pulse; Rats; Rats, Inbred Strains; Sodium Chloride; Sotalol; Stereoisomerism; Time Factors

1976
Pindolol: a pharmacokinetic comparison with other beta-adrenoceptor blocking agents.
    Acta medica Scandinavica. Supplementum, 1977, Volume: 606

    Topics: Adrenergic beta-Antagonists; Alprenolol; Biological Availability; Half-Life; Humans; Metoprolol; Oxprenolol; Pindolol; Practolol; Propranolol; Protein Binding; Sotalol; Timolol

1977
[Properties of beta-adrenergic receptors of heart and lung--studies with "cardioselective" beta-receptor blocking substances].
    Verhandlungen der Deutschen Gesellschaft fur Kreislaufforschung, 1977, Volume: 43

    Topics: Adrenergic beta-Antagonists; Alprenolol; Atenolol; Binding, Competitive; Heart; Lung; Metoprolol; Oxprenolol; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta

1977
Comparison of the effects of nine beta-adrenergic blocking agents on intraocular pressure in rabbits.
    Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1979, Mar-05, Volume: 210, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Drug Tolerance; Ethanolamines; Intraocular Pressure; Metoprolol; Oxprenolol; Pindolol; Practolol; Propranolol; Rabbits; Sotalol; Timolol

1979
Persistent asthma after treatment with beta-blocking agents.
    British journal of diseases of the chest, 1979, Volume: 73, Issue:4

    Topics: Adrenergic beta-Antagonists; Aged; Asthma; Female; Humans; Male; Metoprolol; Middle Aged; Oxprenolol

1979
Effect of metoprolol and oxprenolol on delayed differentiation behaviour in the monkey (Macaca mulatta) [proceedings].
    British journal of pharmacology, 1977, Volume: 59, Issue:3

    Topics: Animals; Discrimination, Psychological; Haplorhini; Macaca mulatta; Male; Metoprolol; Oxprenolol; Propanolamines; Time Factors

1977
Fluorimetric determination of oxprenolol in plasma by direct evaluation of thin-layer chromatograms.
    Journal of chromatography, 1979, Oct-11, Volume: 164, Issue:2

    Topics: Chromatography, Thin Layer; Fluorometry; Humans; Metoprolol; Oxprenolol

1979
Formation of the N-nitroso derivatives of six beta-adrenergic-blocking agents and their genotoxic effects in rat and human hepatocytes.
    Cancer research, 1991, May-01, Volume: 51, Issue:9

    Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Cell Survival; DNA; DNA Damage; DNA Repair; Humans; Liver; Male; Metoprolol; Nadolol; Nitrosamines; Nitrosation; Oxprenolol; Propranolol; Rats; Rats, Inbred Strains; Sodium Nitrite; Sotalol

1991
The effect of beta-adrenergic blockade on leg blood flow with repeated maximal contractions of the triceps surae muscle group in man.
    European journal of applied physiology and occupational physiology, 1990, Volume: 60, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Heart Rate; Humans; Leg; Male; Metoprolol; Muscle Contraction; Oxprenolol; Propranolol; Regional Blood Flow

1990
Separation of the enantiomers of beta-receptor blocking agents and other cationic drugs using a CHIRAL-AGP column. Binding properties and characterization of immobilized alpha 1-acid glycoprotein.
    Journal of chromatography, 1990, Nov-02, Volume: 519, Issue:2

    Topics: Adrenergic beta-Antagonists; Adsorption; Alprenolol; Atenolol; Binding Sites; Butylamines; Chromatography; Metoprolol; Molecular Structure; Orosomucoid; Oxprenolol; Pindolol; Propranolol; Protein Conformation; Spectrometry, Fluorescence; Stereoisomerism

1990
Acute effect of thyroid hormone on insulin secretion in rats.
    Biochemical pharmacology, 1990, Oct-15, Volume: 40, Issue:8

    Topics: Animals; Antithyroid Agents; Blood Glucose; Glucagon; In Vitro Techniques; Insulin; Male; Metoprolol; Oxprenolol; Pancreas; Rats; Rats, Inbred Strains; Thyroid Hormones

1990
Influence of topical and systemic beta-blockers on tear production.
    International ophthalmology, 1989, Volume: 13, Issue:1-2

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Betaxolol; Butoxamine; Drug Administration Routes; Injections, Intramuscular; Lacrimal Apparatus; Male; Metoprolol; Oxprenolol; Propanolamines; Propranolol; Rabbits; Time Factors; Timolol

1989
Side-effects of beta-adrenoceptor blocking drugs assessed by visual analogue scales.
    British journal of clinical pharmacology, 1985, Volume: 19, Issue:2

    Topics: Adrenergic beta-Antagonists; Atenolol; Humans; Metoprolol; Oxprenolol; Propranolol; Surveys and Questionnaires

1985
Beta-blocker brain concentrations in man.
    European journal of clinical pharmacology, 1985, Volume: 28 Suppl

    Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Brain Chemistry; Cats; Humans; Lipid Metabolism; Metoprolol; Oxprenolol; Propranolol; Rats; Solubility; Species Specificity; Subarachnoid Hemorrhage; Tissue Distribution

1985
Side-effects of beta-blockers assessed using visual analogue scales.
    European journal of clinical pharmacology, 1985, Volume: 28 Suppl

    Topics: Acebutolol; Adrenergic beta-Antagonists; Analysis of Variance; Atenolol; Dreams; Fatigue; Humans; Hypertension; Metoprolol; Oxprenolol; Propranolol

1985
A comparison of the pharmacokinetics of atenolol, metoprolol, oxprenolol and propranolol in elderly hypertensive and young healthy subjects.
    British journal of clinical pharmacology, 1985, Volume: 20, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Atenolol; Blood Proteins; Female; Half-Life; Humans; Hypertension; Kinetics; Male; Metoprolol; Oxprenolol; Propranolol; Protein Binding

1985
[Effect of 3-month treatment with propranolol, oxprenolol, metoprolol and pindolol on plasma lipids and lipoproteins in patients with primary arterial hypertension].
    Kardiologia polska, 1985, Volume: 28, Issue:7

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Female; Humans; Hypertension; Lipids; Male; Metoprolol; Middle Aged; Oxprenolol; Pindolol; Propranolol; Time Factors

1985
Antihypertensive effects of 12 beta adrenoceptor antagonists in conscious spontaneously hypertensive rats: relationship to changes in plasma renin activity, heart rate and sympathetic nerve function.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 238, Issue:1

    Topics: Acebutolol; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Blood Pressure; Decerebrate State; Heart; Heart Rate; Hypertension; Isoproterenol; Levobunolol; Male; Metoprolol; Oxprenolol; Propranolol; Rats; Rats, Inbred SHR; Renin; Sympathetic Nervous System; Sympathomimetics; Time Factors

1986
Binding to serum alpha 1-acid glycoprotein and effect of beta-adrenoceptor antagonists in rats with inflammation.
    British journal of pharmacology, 1986, Volume: 88, Issue:3

    Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Heart Rate; Inflammation; Injections, Intravenous; Male; Metoprolol; Orosomucoid; Oxprenolol; Portal Vein; Propranolol; Protein Binding; Rats; Rats, Inbred Strains

1986
Subsidiary class III effects of beta blockers? A comparison of atenolol, metoprolol, nadolol, oxprenolol and sotalol.
    Cardiovascular research, 1986, Volume: 20, Issue:10

    Topics: Action Potentials; Adrenergic beta-Antagonists; Animals; Atenolol; Dose-Response Relationship, Drug; Isomerism; Metoprolol; Muscle Contraction; Nadolol; Oxprenolol; Papillary Muscles; Rabbits; Refractory Period, Electrophysiological; Sotalol

1986
Adsorption of antihypertensives by suspensoids. Part 2. The adsorption of acebutolol, metoprolol, nadolol, oxprenolol, and timolol by attapulgite, charcoal, kaolin and magnesium trisilicate.
    Pharmaceutica acta Helvetiae, 1988, Volume: 63, Issue:1

    Topics: Acebutolol; Adsorption; Antihypertensive Agents; Charcoal; Kaolin; Magnesium; Magnesium Compounds; Magnesium Silicates; Metoprolol; Nadolol; Oxprenolol; Silicic Acid; Silicon; Silicon Compounds; Timolol

1988
Rapid determination of the enantiomers of metoprolol, oxprenolol and propranolol in urine.
    Journal of chromatography, 1987, May-15, Volume: 416, Issue:2

    Topics: Biotransformation; Chromatography, Thin Layer; Humans; Indicators and Reagents; Metoprolol; Oxprenolol; Propranolol; Spectrometry, Fluorescence; Stereoisomerism

1987
Gastrointestinal transit of Oros drug delivery systems in healthy volunteers: a short report.
    British journal of clinical pharmacology, 1985, Volume: 19 Suppl 2

    Topics: Delayed-Action Preparations; Digestive System; Humans; Metoprolol; Oxprenolol

1985
Oros drug delivery systems for the beta-adrenoreceptor antagonists oxprenolol and metoprolol.
    British journal of clinical pharmacology, 1985, Volume: 19 Suppl 2

    Topics: Animals; Delayed-Action Preparations; Humans; Metoprolol; Oxprenolol

1985
Osmotic delivery systems for the beta-adrenoceptor antagonists metoprolol and oxprenolol: design and evaluation of systems for once-daily administration.
    British journal of clinical pharmacology, 1985, Volume: 19 Suppl 2

    Topics: Delayed-Action Preparations; Drug Compounding; Drug Stability; Humans; Hydrogen-Ion Concentration; Kinetics; Metoprolol; Models, Theoretical; Osmosis; Oxprenolol; Solubility

1985
Evaluation of oxprenolol and metoprolol Oros systems in the dog: comparison of in vivo and in vitro drug release, and of drug absorption from duodenal and colonic infusion sites.
    British journal of clinical pharmacology, 1985, Volume: 19 Suppl 2

    Topics: Animals; Colon; Delayed-Action Preparations; Dogs; Duodenum; Female; Intestinal Absorption; Kinetics; Male; Metoprolol; Oxprenolol

1985
Beta-antagonist and secondary hyperparathyroidism in chronic renal failure.
    Nihon Jinzo Gakkai shi, 1985, Volume: 27, Issue:9

    Topics: Adult; Female; Humans; Hyperparathyroidism, Secondary; Kidney Failure, Chronic; Male; Metoprolol; Middle Aged; Oxprenolol

1985
Effect of inflammatory disease on plasma concentrations of three beta-adrenoceptor blocking agents.
    International journal of clinical pharmacology, therapy, and toxicology, 1981, Volume: 19, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Proteins; Blood Sedimentation; Female; Humans; Inflammation; Liver; Male; Metoprolol; Middle Aged; Oxprenolol; Propranolol; Protein Binding

1981
Abrupt withdrawal of chronic beta-blockade: adaptive changes in cyclic AMP and contractility.
    Journal of molecular and cellular cardiology, 1981, Volume: 13, Issue:11

    Topics: Adaptation, Physiological; Adrenergic beta-Antagonists; Animals; Cyclic AMP; Heart; Heart Rate; Humans; Isoproterenol; Male; Metoprolol; Myocardial Contraction; Myocardium; Oxprenolol; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome

1981
Variability in the preventive action of the B-blockers on genetic hypertension in the rat.
    Paroi arterielle, 1980, Volume: 6, Issue:4

    Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Blood Pressure; Dose-Response Relationship, Drug; Hypertension; Male; Metoprolol; Oxprenolol; Pindolol; Practolol; Propranolol; Rats; Rats, Inbred Strains; Species Specificity; Time Factors

1980
Non-invasive assessment of diastolic function in hypertrophic cardiomyopathy on and off beta adrenergic blocking drugs.
    British heart journal, 1982, Volume: 48, Issue:3

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Cardiomyopathy, Hypertrophic; Diastole; Female; Heart; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Oxprenolol; Propranolol

1982
Haemodynamic dose-response effects of intravenous beta-blocking drugs with different ancillary properties in patients with coronary heart disease.
    European heart journal, 1982, Volume: 3, Issue:6

    Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Cardiac Output; Coronary Disease; Dose-Response Relationship, Drug; Heart Rate; Hemodynamics; Humans; Injections, Intravenous; Male; Metoprolol; Middle Aged; Oxprenolol; Practolol; Propranolol; Pulmonary Wedge Pressure

1982
Possible significance of the pharmacological differentiation of beta-blocking agents in hemodynamic effects in essential hypertension.
    Japanese circulation journal, 1983, Volume: 47, Issue:3

    Topics: Acebutolol; Adrenergic beta-Antagonists; Atenolol; Carteolol; Hemodynamics; Humans; Hypertension; Metoprolol; Oxprenolol; Propranolol

1983
[Acute poisoning caused by beta blockers in the adult. Apropos of 7 cases].
    Annales de cardiologie et d'angeiologie, 1983, Volume: 32, Issue:4

    Topics: Acebutolol; Adolescent; Adrenergic beta-Antagonists; Adult; Alcohol Drinking; Bradycardia; Coma; Dose-Response Relationship, Drug; Female; Humans; Male; Metoprolol; Middle Aged; Oxprenolol; Propranolol; Seizures

1983
Clinical trials of adrenergic antagonists in pregnancy hypertension.
    Acta obstetricia et gynecologica Scandinavica. Supplement, 1984, Volume: 118

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Apgar Score; Birth Weight; Female; Fetal Growth Retardation; Humans; Hydralazine; Hypertension; Infant, Newborn; Methyldopa; Metoprolol; Oxprenolol; Pregnancy; Pregnancy Complications, Cardiovascular; Respiratory Distress Syndrome, Newborn

1984
Beta-adrenoceptor blocker pharmacokinetics and the oral contraceptive pill.
    British journal of clinical pharmacology, 1984, Volume: 17 Suppl 1

    Topics: Acebutolol; Adrenergic beta-Antagonists; Contraceptives, Oral; Contraceptives, Oral, Hormonal; Drug Interactions; Female; Humans; Kinetics; Metoprolol; Oxprenolol; Propranolol; Time Factors

1984
Studies with long acting propranolol.
    Postgraduate medical journal, 1984, Volume: 60 Suppl 2

    Topics: Angina Pectoris; Arrhythmias, Cardiac; Delayed-Action Preparations; Half-Life; Heart Rate; Humans; Hypertension; Metoprolol; Oxprenolol; Physical Exertion; Propranolol

1984
Ventilatory response to hypercapnia in normal subjects after propranolol, metoprolol and oxprenolol.
    Respiration; international review of thoracic diseases, 1980, Volume: 39, Issue:3

    Topics: Adult; Carbon Dioxide; Dose-Response Relationship, Drug; Double-Blind Method; Female; Heart Rate; Humans; Hypercapnia; Male; Maximal Expiratory Flow Rate; Metoprolol; Oxprenolol; Propanolamines; Propranolol; Respiration

1980
Gas chromatographic determination of metoprolol in human plasma.
    Journal of chromatography, 1983, Jan-14, Volume: 272, Issue:1

    Topics: Biological Availability; Chromatography, Gas; Humans; Metoprolol; Oxprenolol; Propanolamines

1983
[Behavior of the hemorrheological pattern in subjects with essential hypertension treated with beta-blocking agents. II. Metoprolol and oxprenolol].
    La Clinica terapeutica, 1982, Nov-30, Volume: 103, Issue:4

    Topics: Adult; Blood Flow Velocity; Blood Viscosity; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Oxprenolol; Propanolamines

1982
High-performance liquid chromatographic determination of oxprenolol hydrochloride and metoprolol tartrate in tablets and injections.
    The Analyst, 1982, Volume: 107, Issue:1280

    Topics: Chromatography, High Pressure Liquid; Injections; Metoprolol; Oxprenolol; Propanolamines; Solutions; Tablets

1982
Effects of treatment on circadian rhythms of blood pressure.
    Biotelemetry and patient monitoring, 1981, Volume: 8, Issue:1-2

    Topics: Antihypertensive Agents; Atenolol; Blood Pressure; Circadian Rhythm; Heart Rate; Humans; Hypertension; Labetalol; Metoprolol; Oxprenolol

1981
Chronic administration of oxprenolol and metoprolol attenuate sympathetic cardiovascular responses only in non-adrenalectomized pithed rats.
    Journal of autonomic pharmacology, 1995, Volume: 15, Issue:5

    Topics: Adrenalectomy; Adrenergic beta-Antagonists; Animals; Electric Stimulation; Epinephrine; Hemodynamics; Metoprolol; Norepinephrine; Oxprenolol; Rats; Rats, Sprague-Dawley

1995
On-line column-switching high-performance liquid chromatography analysis of cardiovascular drugs in serum with automated sample clean-up and zone-cutting technique to perform chiral separation.
    Journal of chromatography. A, 1997, Feb-21, Volume: 762, Issue:1-2

    Topics: Cardiovascular Agents; Chromatography, High Pressure Liquid; Diltiazem; Lidocaine; Linear Models; Metoprolol; Online Systems; Oxprenolol; Pindolol; Sensitivity and Specificity; Stereoisomerism; Verapamil

1997
Evaluation of the immobilized artificial membrane phosphatidylcholine. Drug discovery column for high-performance liquid chromatographic screening of drug-membrane interactions.
    Journal of chromatography. A, 1998, Mar-27, Volume: 800, Issue:2

    Topics: Acebutolol; Acetonitriles; Adrenergic beta-Antagonists; Alprenolol; Aniline Compounds; Atenolol; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Membranes, Artificial; Metoprolol; Models, Chemical; Osmolar Concentration; Oxprenolol; Phosphatidylcholines; Pindolol; Propranolol; Reproducibility of Results; Timolol

1998
In vitro permeability of eight beta-blockers through Caco-2 monolayers utilizing liquid chromatography/electrospray ionization mass spectrometry.
    Journal of mass spectrometry : JMS, 1998, Volume: 33, Issue:7

    Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Atenolol; Biological Availability; Caco-2 Cells; Cell Membrane Permeability; Chromatography, Liquid; Epithelial Cells; Humans; Intestinal Absorption; Intestinal Mucosa; Mass Spectrometry; Metoprolol; Molecular Structure; Oxprenolol; Pindolol; Propranolol; Research Design; Timolol

1998
Unexpected difference in enantioselective retention on cellulase (CHB I) silica stationary phase caused by exchange of potassium for sodium ion in the mobile phase.
    Chirality, 1998, Volume: 10, Issue:6

    Topics: Adrenergic beta-Antagonists; Buffers; Cellulase; Metoprolol; Oxprenolol; Potassium; Silicon Dioxide; Sodium; Spectrophotometry, Ultraviolet; Stereoisomerism; Temperature

1998
Iontophoretic in vivo transdermal delivery of beta-blockers in hairless rats and reduced skin irritation by liposomal formulation.
    Pharmaceutical research, 2003, Volume: 20, Issue:9

    Topics: Administration, Cutaneous; Adrenergic beta-Antagonists; Animals; Biological Transport; Chromatography, High Pressure Liquid; Drug Carriers; Injections, Intravenous; Iontophoresis; Irritants; Liposomes; Metoprolol; Oxprenolol; Propranolol; Rats; Skin; Skin Absorption; Sotalol; Stereoisomerism; Timolol

2003
Enantiomeric separation by using nano-liquid chromatography with on-column focusing.
    Journal of separation science, 2008, Volume: 31, Issue:14

    Topics: Adrenergic beta-Antagonists; Alprenolol; Calibration; Chromatography, Liquid; Metoprolol; Nanotechnology; Oxprenolol; Particle Size; Propranolol; Reproducibility of Results; Silicon Dioxide; Stereoisomerism; Time Factors; Vancomycin

2008
The interactivities with lipid membranes differentially characterize selective and nonselective beta1-blockers.
    European journal of anaesthesiology, 2010, Volume: 27, Issue:9

    Topics: Adrenergic beta-Antagonists; Alprenolol; Anesthesia; Anesthetics; Atenolol; Biomimetics; Lipid Bilayers; Lipids; Liposomes; Membranes, Artificial; Metoprolol; Oxprenolol; Propanolamines; Propranolol; Receptors, Adrenergic, beta

2010
Beta-blocker carteolol and oxprenolol produce cutaneous analgesia in response to needle pinpricks in the rat.
    Neurological research, 2023, Volume: 45, Issue:4

    Topics: Acebutolol; Analgesia; Anesthetics, Local; Animals; Bupivacaine; Butoxamine; Carteolol; Dose-Response Relationship, Drug; Epinephrine; Metoprolol; Oxprenolol; Pain; Rats; Rats, Sprague-Dawley

2023