metoprolol and isosorbide dinitrate

metoprolol has been researched along with isosorbide dinitrate in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199011 (33.33)18.7374
1990's10 (30.30)18.2507
2000's6 (18.18)29.6817
2010's6 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jolivette, LJ; Ward, KW1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Lydtin, H; Trenkwalder, P1
Julínek, J; Meluzín, J; Novák, M; Simek, P; Spinarová, L; Stejfa, M; Toman, J; Zeman, K1
Beyerle, A; Lehmann, G; Reiniger, G; Rudolph, W; Wolf, H1
Katsenovich, RA; Kostko, SZ1
Metelitsa, VI1
Dusleag, J; Eber, B; Fluch, N; Gasser, R; Klein, W; Kronberger-Schaffer, E; Rotman, B; Weinrauch, V1
Greenblatt, DJ; Labedzki, L; Neugebauer, G; Ochs, HR1
Cocco, C; Franceschini, L; Menegatti, G; Nidasio, GP; Rizzotti, P; Vassanelli, C1
Andreoli, C; Cioni, G; Mattioli, G1
Hugenholtz, PG; Michels, R; Serruys, PW; Simoons, ML1
Hesse, B; Jensen, G; Rasmussen, S; Trautner, F2
Hagemeijer, F; Santoso, T; van Mechelen, R1
Blasini, R; Brügmann, U; Froer, KL; Hall, D; Mannes, A; Rudolph, W1
Asakuma, S; Iwasaki, T; Ohyanagi, M1
Forfang, K; Gullestad, L1
Fujii, H; Kikuta, K; Miyagi, H; Nakamura, N; Ogawa, H; Yasue, H1
Buser, GA; Gold, MR; Kim, HJ; Peters, RW1
Hjalmarson, A; Johansson, M; Lomsky, M; Lurje, L; Vahisalo, R; Wennerblom, B; Westberg, S1
Dakik, HA; Farmer, JA; He, ZX; Kleiman, NS; Mahmarian, JJ; Pratt, CM; Verani, MS; Wendt, JA1
Bertschinger, P; Bühler, H; Kuhn, M; Meyer, MI1
Karlsson, T; Lurje, L; Tygesen, H; Vahisalo, R; Wennerblom, B1
Kopff, A; Kopff, M; Kowalczyk, E1
Barnett, PG; Boden, WE; Bowen, J; Deaton, C; Dunbar, SB; Goeree, R; Hartigan, PM; Jurkovitz, C; Kaufman, S; Kolm, P; Lewis, C; Mancini, GB; Maron, DJ; O'Rourke, RA; Spertus, JA; Teo, KK; Veledar, E; Weintraub, WS; Zhang, W; Zhang, Z1
Guo, WZ; Ji, H; Li, D; Lu, CL; Yan, ZH1
Shimosawa, T; Shintani-Ishida, K; Tsushima, K; Ueyama, T; Unuma, K; Yahagi, N; Yoshida, K1
Hayashi, H1
Dong, YM; Li, CL; Li, N; Lu, NW1

Reviews

1 review(s) available for metoprolol and isosorbide dinitrate

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

12 trial(s) available for metoprolol and isosorbide dinitrate

ArticleYear
Amlodipine in patients with stable angina pectoris treated with nitrates and beta-blockers. The influence on exercise tolerance, systolic and diastolic functions of the left ventricle.
    International journal of cardiology, 1992, Volume: 37, Issue:1

    Topics: Amlodipine; Angina Pectoris; Diastole; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Electrocardiography; Exercise Test; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Metipranolol; Metoprolol; Myocardial Infarction; Nitroglycerin; Systole; Ventricular Function, Left

1992
[Effectiveness of various combination therapies in patients with coronary heart disease].
    Herz, 1990, Volume: 15, Issue:6

    Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Coronary Disease; Diltiazem; Double-Blind Method; Drug Therapy, Combination; Hemodynamics; Humans; Isosorbide Dinitrate; Metoprolol; Nisoldipine; Nitrates

1990
[Ways of individualizing use of anti-anginal preparations].
    Kardiologiia, 1989, Volume: 29, Issue:2

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Clinical Trials as Topic; Dose-Response Relationship, Drug; Exercise Test; Humans; Isosorbide Dinitrate; Metoprolol; Nifedipine; Placebos; Propranolol; Vasodilator Agents

1989
[Do thrombocyte aggregation inhibitors modify silent episodes of unstable angina pectoris in combined anti-angina therapy?].
    Zeitschrift fur Kardiologie, 1989, Volume: 78 Suppl 2

    Topics: Aged; Angina Pectoris; Angina, Unstable; Aspirin; Coronary Circulation; Diltiazem; Drug Therapy, Combination; Electrocardiography, Ambulatory; Female; Humans; Isosorbide Dinitrate; Male; Metoprolol; Middle Aged; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic

1989
Time sequence of anginal pain.
    Clinical cardiology, 1986, Volume: 9, Issue:4

    Topics: Adult; Aged; Angina Pectoris; Circadian Rhythm; Female; Humans; Isosorbide Dinitrate; Male; Metoprolol; Middle Aged; Nifedipine; Pain; Seasons; Time

1986
[Isosorbide dinitrate in exercise induced angina pectoris despite use of beta-blocking treatment. Clinical and hematological effects assessed by isotope angiocardiography].
    Ugeskrift for laeger, 1982, Nov-01, Volume: 144, Issue:44

    Topics: Adult; Aged; Angina Pectoris; Angiocardiography; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Isosorbide Dinitrate; Male; Metoprolol; Middle Aged; Physical Exertion; Propanolamines; Radionuclide Imaging

1982
Haemodynamic and clinical effects of isosorbide-dinitrate in patients with severe effort angina on beta-blocking treatment.
    European journal of clinical pharmacology, 1983, Volume: 24, Issue:2

    Topics: Adult; Aged; Angina Pectoris; Drug Therapy, Combination; Female; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Metoprolol; Middle Aged; Propanolamines

1983
Comparison of efficacy of nisoldipine, metoprolol, and isosorbide dinitrate in patients with stable exertional angina: a randomized, cross-over, placebo-controlled study.
    International journal of cardiology, 1995, Volume: 48, Issue:2

    Topics: Administration, Oral; Aged; Angina Pectoris; Blood Pressure; Cross-Over Studies; Exercise Test; Exercise Tolerance; Female; Heart Rate; Humans; Isosorbide Dinitrate; Male; Metoprolol; Middle Aged; Nisoldipine; Physical Exertion; Rest; Treatment Outcome

1995
Effects on heart rate variability of isosorbide-5-mononitrate and metoprolol in patients with recent onset of angina pectoris.
    Cardiology, 1998, Volume: 89, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Angina Pectoris; Electrocardiography, Ambulatory; Female; Heart Rate; Humans; Isosorbide Dinitrate; Male; Metoprolol; Middle Aged; Vasodilator Agents

1998
Intensive medical therapy versus coronary angioplasty for suppression of myocardial ischemia in survivors of acute myocardial infarction: a prospective, randomized pilot study.
    Circulation, 1998, Nov-10, Volume: 98, Issue:19

    Topics: Adrenergic beta-Antagonists; Adult; Angioplasty, Balloon, Coronary; Diltiazem; Female; Humans; Isosorbide Dinitrate; Male; Metoprolol; Middle Aged; Myocardial Infarction; Myocardial Ischemia; Pilot Projects; Prospective Studies; Tomography, Emission-Computed, Single-Photon; Vasodilator Agents

1998
Circadian variation of heart rate variability and the rate of autonomic change in the morning hours in healthy subjects and angina patients.
    International journal of cardiology, 2001, Volume: 79, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Angina Pectoris; Aortic Bodies; Autonomic Nervous System; Circadian Rhythm; Electrocardiography, Ambulatory; Female; Heart Rate; Humans; Isosorbide Dinitrate; Male; Metoprolol; Middle Aged; Reference Values; Vasodilator Agents

2001
Effect of PCI on quality of life in patients with stable coronary disease.
    The New England journal of medicine, 2008, Aug-14, Volume: 359, Issue:7

    Topics: Adrenergic beta-Antagonists; Amlodipine; Angina Pectoris; Angioplasty, Balloon, Coronary; Aspirin; Calcium Channel Blockers; Clopidogrel; Combined Modality Therapy; Coronary Disease; Cross-Over Studies; Drug Therapy, Combination; Female; Health Status; Humans; Isosorbide Dinitrate; Male; Metoprolol; Middle Aged; Patient Satisfaction; Platelet Aggregation Inhibitors; Quality of Life; Stents; Surveys and Questionnaires; Ticlopidine; Vasodilator Agents

2008

Other Studies

20 other study(ies) available for metoprolol and isosorbide dinitrate

ArticleYear
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure.
    Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7

    Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution

2005
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
[Therapy of coronary disease].
    Deutsche medizinische Wochenschrift (1946), 1992, Jan-03, Volume: 117, Issue:1

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Aspirin; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Diltiazem; Dipyridamole; Drug Therapy, Combination; Humans; Isosorbide Dinitrate; Metoprolol; Nitrates; Smoking; Verapamil

1992
[Drugs in secondary prevention of ischemic heart disease: achievements, problems and prospects].
    Kardiologiia, 1989, Volume: 29, Issue:11

    Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Coronary Disease; Female; Humans; Isosorbide Dinitrate; Male; Metoprolol; Nadolol; Nifedipine; Nitrates; Nitroglycerin; Propranolol; Verapamil

1989
Influence of beta-blocker coadministration on the kinetics of isosorbide mononitrate and dinitrate.
    Klinische Wochenschrift, 1986, Dec-01, Volume: 64, Issue:23

    Topics: Adrenergic beta-Antagonists; Adult; Drug Interactions; Female; Humans; Isosorbide Dinitrate; Male; Metipranolol; Metoprolol; Propranolol

1986
Comparison of different pharmacological interventions on enzymatic parameters during acute myocardial infarction.
    Clinical biochemistry, 1987, Volume: 20, Issue:6

    Topics: Adult; Aged; Clinical Enzyme Tests; Creatine Kinase; Dipyridamole; Female; Heart; Heparin; Humans; Isoenzymes; Isosorbide Dinitrate; Male; Metoprolol; Middle Aged; Myocardial Infarction; Myocardium; Necrosis; Nifedipine; Nitroglycerin; Streptokinase; Verapamil

1987
Treatment of unstable angina with emphasis on calcium antagonists.
    Giornale italiano di cardiologia, 1984, Volume: 14, Issue:11

    Topics: Angina Pectoris; Angina, Unstable; Anticoagulants; Coronary Circulation; Coronary Disease; Electrocardiography; Humans; Isosorbide Dinitrate; Metoprolol; Nifedipine; Nitroglycerin; Oxygen Consumption; Propranolol; Verapamil

1984
Benefits from adding nifedipine to the treatment of unstable angina when beta-blockade and isosorbide dinitrate have proved inadequate.
    Herz, 1982, Volume: 7, Issue:2

    Topics: Aged; Angina Pectoris, Variant; Coronary Disease; Coronary Vasospasm; Drug Therapy, Combination; Female; Humans; Isosorbide Dinitrate; Male; Metoprolol; Nifedipine; Nitroglycerin; Physical Exertion; Propanolamines; Pyridines

1982
[Disparate efficacy of isosorbide dinitrate, in sustained-release form, during acute and chronic administration (author's transl)].
    Herz, 1980, Volume: 5, Issue:5

    Topics: Angina Pectoris; Blood Pressure; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-Blind Method; Exercise Test; Heart Rate; Humans; Isosorbide Dinitrate; Metoprolol; Placebos; Random Allocation

1980
The effects of antianginal drugs on energy expenditure during exercise in normal subjects.
    Japanese circulation journal, 1995, Volume: 59, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Calcium Channel Blockers; Energy Metabolism; Ethanolamines; Exercise; Humans; Isosorbide Dinitrate; Male; Metoprolol; Middle Aged; Nicardipine; Propranolol

1995
[Drug therapy of angina pectoris. Are the possibilities exploited well enough?].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1995, Aug-10, Volume: 115, Issue:18

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Angina, Unstable; Female; Humans; Isosorbide Dinitrate; Male; Metoprolol; Middle Aged; Propranolol; Retrospective Studies; Timolol

1995
Ischemically mediated sustained monomorphic ventricular tachycardia. Resolution with anti-ischemic therapy.
    Chest, 1993, Volume: 104, Issue:5

    Topics: Coronary Angiography; Diltiazem; Drug Therapy, Combination; Electrocardiography; Humans; Isosorbide Dinitrate; Male; Metoprolol; Middle Aged; Myocardial Ischemia; Procainamide; Tachycardia, Ventricular

1993
[Ticlopidine-induced cholestasis].
    Schweizerische medizinische Wochenschrift, 1999, Oct-02, Volume: 129, Issue:39

    Topics: Aged; Aged, 80 and over; Angina Pectoris; Aspirin; Chemical and Drug Induced Liver Injury; Cholestasis; Drug Therapy, Combination; Humans; Incidence; Isosorbide Dinitrate; Liver Function Tests; Male; Metoprolol; Myocardial Infarction; Platelet Aggregation Inhibitors; Stents; Ticlopidine

1999
[Inhibition of adenosine deaminase activity by drugs influencing the cardiovascular system].
    Polskie Archiwum Medycyny Wewnetrznej, 2004, Volume: 111, Issue:6

    Topics: Adenosine; Adenosine Deaminase Inhibitors; Animals; Aspirin; Cardiovascular Agents; Cardiovascular System; Deoxyadenosines; Female; Fibrinolytic Agents; Isoenzymes; Isosorbide Dinitrate; Male; Metoprolol; Molsidomine; Rabbits; Random Allocation; Simvastatin; Vasodilator Agents; Vasomotor System

2004
Influence of drug treatment on glucocorticoid receptor levels in patients with coronary heart disease.
    Chinese medical journal, 2010, Volume: 123, Issue:13

    Topics: Aged; Blotting, Western; Coronary Disease; Female; Humans; Isosorbide Dinitrate; Lovastatin; Male; Metoprolol; Middle Aged; Nifedipine; Receptors, Glucocorticoid

2010
Restraint stress induces connexin-43 translocation via α-adrenoceptors in rat heart.
    Circulation journal : official journal of the Japanese Circulation Society, 2010, Volume: 74, Issue:12

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-1 Receptor Antagonists; Animals; Connexin 43; Gap Junctions; Isosorbide Dinitrate; Male; Metoprolol; Myocardial Ischemia; Myocardium; Nitric Oxide Donors; Propranolol; Protein Transport; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Restraint, Physical; Stress, Physiological

2010
Does remodeling of gap junctions and connexin expression contribute to arrhythmogenesis? Study in an immobilization rat model.
    Circulation journal : official journal of the Japanese Circulation Society, 2010, Volume: 74, Issue:12

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-1 Receptor Antagonists; Animals; Arrhythmias, Cardiac; Connexin 43; Gap Junctions; Isosorbide Dinitrate; Male; Metoprolol; Myocardial Ischemia; Myocardium; Nitric Oxide Donors; Propranolol; Protein Transport; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Restraint, Physical; Stress, Physiological

2010
A novel micellar per aqueous liquid chromatographic method for simultaneous determination of diltiazem hydrochloride, metoprolol tartrate and isosorbide mononitrate in human serum.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2014, Sep-15, Volume: 967

    Topics: Chromatography, Liquid; Diltiazem; Drug Stability; Humans; Hydrogen-Ion Concentration; Isosorbide Dinitrate; Linear Models; Metoprolol; Micelles; Reproducibility of Results; Sensitivity and Specificity

2014