metoprolol has been researched along with felodipine in 103 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (21.36) | 18.7374 |
| 1990's | 41 (39.81) | 18.2507 |
| 2000's | 19 (18.45) | 29.6817 |
| 2010's | 19 (18.45) | 24.3611 |
| 2020's | 2 (1.94) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Holliwell, DL; Leenen, FH | 1 |
| Garanin, G; Hoffmann, J; Klaus, D; Lohr, E; Wetzchewald, D | 2 |
| Havu, N; Nordlander, M | 1 |
| Bengtsson, C; Brun, J; Fröberg, L; Kronmann, P; Olsson, LB; Scherstén, B; Skoog, P; Tibblin, G; Tygesen, G | 1 |
| Littler, WA | 1 |
| Dahlöf, B; Hosie, J | 2 |
| Dimenäs, E; Svärdsudd, K; Wallander, MA; Wiklund, I | 2 |
| Strauer, BE | 1 |
| Aberg, J; Gelin, A; Karlberg, BE; Larsson, R; Regårdh, CG | 1 |
| Bengtsson, C; Bengtsson, L; Lapidus, L; Lundgren, H | 1 |
| Horton, R; Nordlander, M; Thalén, P | 1 |
| Bengtsson-Hasselgren, B; Elmfeldt, D; Moberg, L; Rönn, O | 1 |
| Nordborg, C | 3 |
| Chow, J | 1 |
| Groom, P; Peers, E; Richardson, PD; Simpson, RJ; Singh, B; Ward, DE | 1 |
| Burton, RH; Davis, RH; Freeling, P; Goves, JR; Orme-Smith, EA | 1 |
| Burton, RH; Davis, RH; Freeling, P; Goves, JR; Graham-Evans, JN; Orne-Smith, EA; Osborne, CJ; Ward, DE | 1 |
| Amery, A; De Schaepdryver, A; Fagard, R; Lijnen, P; Moerman, E; Staessen, J | 1 |
| Friberg, P; Nordlander, M; Wåhlander, H | 1 |
| Hardebo, JE; Kåhrström, J; Nordborg, C | 1 |
| Amery, A; Fagard, R; Lijnen, P; Moerman, E; Staessen, J | 1 |
| Amery, A; Fagard, R; Staessen, J | 1 |
| Friberg, P; Nordlander, M | 1 |
| Jack, DB; Kendall, MJ; Laugher, S; Smith, SR; Wilkins, MR | 1 |
| Barbour, MP; Forret, EA; Hill, TW; Lawrie, TD; Lorimer, AR; McAlpine, HM; Rae, AP; Simpson, IA | 1 |
| Clement, DL; De Pue, NY | 1 |
| Bengtsson, B; Edgar, B; Raner, S; Rönn, O | 1 |
| Been, M; de Vane, PJ; Hillis, WS; Hornung, RS; Jamieson, RR; Jones, CR; Rae, AP | 1 |
| Hallbäck-Nordlander, MI; Lundin, SA | 1 |
| Ahlström, P; Angman, K; Emanuelsson, H; Kujacic, V; Lundkvist, L; Rosenqvist, U; Tisell, A | 1 |
| Elmfeldt, D; Trenkwalder, P | 1 |
| Andersson, OK; Dahlöf, B | 1 |
| Jennings, GL; Korner, P; Laufer, E; Reid, C; Sudhir, K | 1 |
| Bergstrand, R; Eriksson, M; Lidman, K; Nyberg, G; Olofsson, B | 1 |
| Janssen, BJ; Oosting, J; Struyker-Boudier, HA; Tyssen, CM | 1 |
| Abrahamsson, B; Edgar, B; Lidman, K; Wingstrand, K | 1 |
| Hoffmann, J | 1 |
| Borgholst, O; Dahlöf, B; Ekblad, G; Engstrand, C; Grundestam, I; Jönsson, L; Lindh, A | 1 |
| Dahlöf, B; Hosie, J; Klein, G | 1 |
| Bune, AJ; Chalmers, JP; Russell, AE; Tonkin, AL; West, MJ; Wing, LM | 1 |
| Kendall, MJ | 1 |
| Elmfeldt, DB; Gordon, RD; Klemm, SA; Tunny, TJ; Wicks, JR | 1 |
| Afonso, LC; Bedford-Rice, K; Raman, BB; Sowers, JR; Standley, PR | 1 |
| Lähteenmäki, TA; Sievi, E; Vapaatalo, H | 1 |
| Karppanen, H; Laakso, J; Malmberg, L; Mervaala, EM; Pörsti, I; Teräväinen, TL; Vapaatalo, H | 1 |
| Sawicki, PT | 1 |
| Aberg, J; Abrahamsson, B; Grind, M; Nyberg, G; Olofsson, B | 1 |
| Bernink, P; Bosma, A; Dunselman, P; Kragten, H; Liem, AH; Verdel, G | 1 |
| Bossi, M; Tiberti, G | 1 |
| Andersson, F; Andersson, OK; Kartman, B | 1 |
| Andersson, OK | 1 |
| Airaksinen, KE; Huikuri, HV; Sellin, L; Ylitalo, A | 1 |
| Egstrup, K; Ellström, J; Emanuelsson, H; Forsby, M; Glud, T; Nikus, K; Pater, C; Scheibel, M; Tisell, A; Tötterman, KJ | 1 |
| Klein, G | 1 |
| Boivin, JM; Zannad, F | 1 |
| Dahlöf, B; Detry, JM; Gundersen, T; Hosie, J; Januszewicz, W; Lindström, CJ; Magometschnigg, D; Puig, JG; Safar, M; Tanser, P; Toutouzas, P; Waeber, B | 1 |
| Adair, CT; Anderson, DC; Cameron, ME; Jones, DW; King, NS; Miller, ME; Willoughby, DL; Wofford, MR | 1 |
| Haria, M; Markham, A; Plosker, GL | 1 |
| Elliott, HL; Hosie, J; MacDonald, TM; McLay, JS | 1 |
| Khapaev, BA; Ol'binskaia, LI; Zheleznykh, EA | 1 |
| Gokce, N; Holbrook, M; Hunter, LM; Keaney, JF; Palmisano, J; Vigalok, E; Vita, JA | 1 |
| Dahlöf, B; Degl' Innocenti, A; Elmfeldt, D; Gundersen, T; Hosie, J; Januszewicz, W; Lindström, CJ; Magometschnigg, D; Puig, JG; Tanser, P; Toutouzas, P; Waeber, B; Wiklund, I | 1 |
| Frishman, WH; Hainer, JW; Sugg, J | 1 |
| Grimm, E; Herrmann, D; Kintscher, U; Scholze, J; Unger, T | 1 |
| Chen, YY; Liu, HL; Shen, FR; Sun, NL; Tao, J; Wu, HY; Xiang, XP; Yu, ZQ; Zhang, FC; Zhang, L; Zhang, WZ; Zhao, JA | 1 |
| Fu, GY; Liu, ZY; Wang, R; Wang, WG; Yun, LH | 1 |
| Borst, M; Braun, M; Edelmann, F; Knapp, M; Schön, S; Schwencke, C; Simonis, G; Strasser, RH; Weinbrenner, C | 1 |
| Bai, F; Chang, P; Chen, XH; Guo, XY; Hu, H; Li, XL; Liu, PJ; Shen, XP; Xu, D; Yu, J; Zhang, Y; Zhao, F | 1 |
| Andras, C; Csiki, Z; Garai, I; Papp, G; Shemirani, AH; Zeher, M; Zsori, KS | 1 |
| Bai, F; Lin, X; Ma, R; Xu, D; Yang, L; Yu, J; Zhao, F | 1 |
| Anyfanti, P; Doumas, M; Lazaridis, N | 1 |
| Kallem, RR; Ramesh, M; Seshagirirao, JV | 1 |
| Doumas, M; Papademetriou, V; Viigimaa, M | 1 |
| Bai, F; Hu, H; Lin, X; Liu, P; Ma, R; Yang, L; Yu, J; Zhao, F | 1 |
| Seftel, AD | 1 |
| Hammad, MA; Mohamed, AA; Mohamed, AM; Omar, MA | 1 |
| Di, Z; Li, Y; Li, Z; Liu, N; Liu, Y; Mei, X; Yan, K; Yang, Y; Yang, Z; Yu, F; Zhang, H; Zhao, S | 1 |
| Chen, M; Li, Y; Liu, Y; Mei, L; Mei, X; Xie, X; Yang, Y; Yu, F; Zhou, J | 1 |
| Abdelaleem, EA; Emam, AA; Hassan, ES; Naguib, IA | 1 |
| Tchernev, G | 1 |
5 review(s) available for metoprolol and felodipine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Improving the therapeutic balance between efficacy and tolerability in antihypertensive drugs--the rationale and benefits of combining felodipine and metoprolol.
Topics: Antihypertensive Agents; Drug Combinations; Drug Therapy, Combination; Felodipine; Humans; Metoprolol; Randomized Controlled Trials as Topic; Treatment Outcome | 1995 |
A felodipine-metoprolol extended-release tablet: its properties and clinical development.
Topics: Antihypertensive Agents; Chemistry, Pharmaceutical; Delayed-Action Preparations; Felodipine; Hemodynamics; Humans; Metoprolol; Tablets | 1995 |
Approaches to meeting the criteria for fixed dose antihypertensive combinations. Focus on metoprolol.
Topics: Dose-Response Relationship, Drug; Drug Combinations; Felodipine; Humans; Hypertension; Metoprolol | 1995 |
Felodipine/metoprolol: a review of the fixed dose controlled release formulation in the management of essential hypertension.
Topics: Drug Therapy, Combination; Felodipine; Hemodynamics; Humans; Hypertension; Kidney; Metoprolol; Quality of Life | 2000 |
44 trial(s) available for metoprolol and felodipine
| Article | Year |
|---|---|
Antihypertensive effect of felodipine associated with persistent sympathetic activation and minimal regression of left ventricular hypertrophy.
Topics: Adult; Aged; Analysis of Variance; Cardiomegaly; Double-Blind Method; Drug Therapy, Combination; Felodipine; Female; Heart Rate; Heart Ventricles; Humans; Hypertension; Male; Metoprolol; Middle Aged; Norepinephrine; Single-Blind Method; Sympathetic Nervous System; Ultrasonography; Vascular Resistance; Ventricular Function, Left | 1992 |
Regression of left ventricular hypertrophy during long-term antihypertensive treatment--a comparison between felodipine and the combination of felodipine and metoprolol.
Topics: Adult; Analysis of Variance; Blood Pressure; Cardiomegaly; Double-Blind Method; Drug Therapy, Combination; Felodipine; Female; Heart Rate; Heart Ventricles; Humans; Hypertension; Male; Metoprolol; Middle Aged; Ultrasonography | 1992 |
Optimal felodipine dose when combined with metoprolol in arterial hypertension: a Swedish multicenter study within primary health care. Swedish General Practitioner Felodipine Study Group.
Topics: Adult; Aged; Blood Pressure; Body Weight; Delayed-Action Preparations; Double-Blind Method; Drug Therapy, Combination; Felodipine; Female; Heart Rate; Humans; Hypertension; Male; Metoprolol; Middle Aged; Multicenter Studies as Topic; Patient Compliance; Randomized Controlled Trials as Topic; Sweden | 1990 |
Comparison of felodipine with nifedipine as additions to metoprolol in the treatment of hypertension. U.K. Multicentre Hospital Group.
Topics: Adult; Aged; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Felodipine; Heart Rate; Humans; Hypertension; Metoprolol; Middle Aged; Nifedipine; Randomized Controlled Trials as Topic | 1990 |
Antihypertensive efficacy and tolerability of a fixed combination of metoprolol and felodipine in comparison with the individual substances in monotherapy. The Swedish/United Kingdom Study Group.
Topics: Adult; Aged; Blood Pressure; Body Weight; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Felodipine; Female; Heart Rate; Humans; Hypertension; Male; Metoprolol; Middle Aged | 1990 |
Evaluation of three methods of symptom reporting in a clinical trial of felodipine.
Topics: Adult; Adverse Drug Reaction Reporting Systems; Aged; Felodipine; Female; Humans; Male; Metoprolol; Middle Aged; Surveys and Questionnaires | 1991 |
Aspects of quality of life on treatment with felodipine.
Topics: Adult; Aged; Analysis of Variance; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Felodipine; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Quality of Life; Single-Blind Method; Statistics as Topic; Surveys and Questionnaires | 1991 |
Antihypertensive drugs and glucose metabolism: comparison between a diuretic, a beta-blocker and felodipine, a new calcium antagonist in subjects with arterial hypertension and diabetes.
Topics: Aged; Blood Glucose; Diabetes Mellitus; Double-Blind Method; Felodipine; Female; Glucose Tolerance Test; Humans; Hydrochlorothiazide; Hypertension; Male; Metoprolol; Middle Aged | 1990 |
A double-blind comparison of felodipine and hydrochlorothiazide added to metoprolol to control hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Dizziness; Double-Blind Method; Drug Therapy, Combination; Felodipine; Female; Headache; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Metoprolol; Middle Aged; Nitrendipine; Random Allocation; Time Factors | 1988 |
Control of hypertension in elderly patients with felodipine and metoprolol: a double-blind, placebo-controlled clinical trial.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Felodipine; Heart Rate; Humans; Hypertension; Metoprolol; Nitrendipine; Random Allocation | 1987 |
Hypertension in the elderly. Its diagnosis in general practice and treatment with felodipine and metoprolol.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Felodipine; Heart Rate; Humans; Hypertension; Metoprolol; Nitrendipine; Random Allocation | 1987 |
Pharmacokinetic interactions between felodipine and metoprolol.
Topics: Adult; Double-Blind Method; Drug Interactions; Felodipine; Half-Life; Humans; Kinetics; Male; Metoprolol; Nitrendipine; Time Factors | 1987 |
Effects of felodipine on rest and exercise heart rate and blood pressure in hypertensive patients.
Topics: Adult; Antihypertensive Agents; Bendroflumethiazide; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Felodipine; Female; Heart Rate; Humans; Hypertension; Male; Metoprolol; Middle Aged; Nifedipine; Physical Exertion; Random Allocation | 1985 |
Acute haemodynamic effects of felodipine and verapamil in man, singly and with metoprolol.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Drug Interactions; Electrocardiography; Felodipine; Heart Rate; Hemodynamics; Humans; Male; Metoprolol; Nifedipine; Regional Blood Flow; Stroke Volume; Vascular Resistance; Verapamil | 1985 |
Felodipine versus placebo in stable effort-induced angina pectoris in patients inadequately controlled with metoprolol--a dose-finding study.
Topics: Aged; Angina Pectoris; Cross-Over Studies; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-Blind Method; Felodipine; Female; Humans; Male; Metoprolol; Middle Aged | 1994 |
Assessment of effects of two anti-hypertensive regimens on overall cardiovascular risk.
Topics: Adolescent; Adult; Aged; Blood Pressure; Cardiovascular Diseases; Cholesterol; Diuretics; Drug Therapy, Combination; Felodipine; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Metoprolol; Middle Aged; Prazosin; Risk Factors | 1995 |
Aiming for steady 24-hour plasma concentrations: a comparison of two calcium antagonist and beta-blocker combinations.
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Atenolol; Calcium Channel Blockers; Chromatography, Gas; Chromatography, Liquid; Delayed-Action Preparations; Drug Combinations; Electrocardiography; Felodipine; Humans; Male; Metoprolol; Nifedipine | 1993 |
Antihypertensive efficacy and tolerability of a new once-daily felodipine-metoprolol combination compared with each component alone. The Swedish/UK Study Group.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Body Weight; Delayed-Action Preparations; Double-Blind Method; Drug Combinations; Electrocardiography; Felodipine; Female; Heart Rate; Humans; Hypertension; Male; Metoprolol; Middle Aged; Patient Compliance | 1993 |
Comparison of a felodipine-metoprolol combination tablet vs each component alone as antihypertensive therapy. The German Multicentre Study Group.
Topics: Adult; Aged; Blood Pressure; Delayed-Action Preparations; Double-Blind Method; Drug Combinations; Felodipine; Female; Heart Rate; Humans; Hypertension; Male; Metoprolol; Middle Aged; Patient Compliance | 1993 |
Improved antihypertensive efficacy of the felodipine-metoprolol extended-release tablet compared with each drug alone.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Body Weight; Delayed-Action Preparations; Double-Blind Method; Drug Combinations; Electrocardiography; Felodipine; Female; Heart Rate; Humans; Hypertension; Male; Metoprolol; Middle Aged | 1993 |
The long-term antihypertensive efficacy and safety of a new felodipine-metoprolol combination tablet. The Swedish/UK and German Study Groups.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Body Weight; Delayed-Action Preparations; Double-Blind Method; Drug Combinations; Electrocardiography; Felodipine; Female; Heart Rate; Humans; Male; Metoprolol; Middle Aged | 1993 |
Felodipine, metoprolol and their combination compared with placebo in isolated systolic hypertension in the elderly.
Topics: Aged; Aged, 80 and over; Blood Pressure; Double-Blind Method; Drug Combinations; Felodipine; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Metoprolol; Middle Aged; Placebos; Systole | 1994 |
Effects of felodipine, metoprolol and their combination on blood pressure at rest and during exercise and on volume regulatory hormones in hypertensive patients.
Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Exercise; Exercise Test; Felodipine; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Renin | 1995 |
Stabilization of glomerular filtration rate over 2 years in patients with diabetic nephropathy under intensified therapy regimens. Diabetes Treatment and Teaching Programmes Working Group.
Topics: Adult; Antihypertensive Agents; Diabetic Nephropathies; Felodipine; Female; Follow-Up Studies; Glomerular Filtration Rate; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Inulin; Male; Metoprolol; Middle Aged; Prospective Studies; Ramipril; Time Factors | 1997 |
Addition of felodipine to metoprolol vs replacement of metoprolol by felodipine in patients with angina pectoris despite adequate beta-blockade. Results of the Felodipine ER and Metoprolol CR in Angina (FEMINA) Study. Working Group on Cardiovascular Resea
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Calcium Channel Blockers; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Electrocardiography; Exercise Test; Felodipine; Female; Humans; Male; Metoprolol; Middle Aged | 1997 |
Improved efficacy with maintained tolerability in the treatment of primary hypertension. Comparison between the felodipine-metoprolol combination tablet and monotherapy with enalapril. Swedish Multicentre Group.
Topics: Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Drug Combinations; Enalapril; Felodipine; Female; Humans; Hypertension; Metoprolol; Middle Aged; Tablets; Treatment Outcome | 1999 |
Effects of combination antihypertensive therapy on baroreflex sensitivity and heart rate variability in systemic hypertension.
Topics: Aged; Antihypertensive Agents; Baroreflex; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Echocardiography, Doppler, Color; Electrocardiography, Ambulatory; Enalapril; Felodipine; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Metoprolol; Middle Aged; Phenylephrine | 1999 |
Antianginal efficacy of the combination of felodipine-metoprolol 10/100 mg compared with each drug alone in patients with stable effort-induced angina pectoris: a multicenter parallel group study. The TRAFFIC Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Calcium Channel Blockers; Double-Blind Method; Drug Therapy, Combination; Exercise Test; Exercise Tolerance; Felodipine; Female; Follow-Up Studies; Humans; Male; Metoprolol; Middle Aged; Retrospective Studies; Treatment Outcome | 1999 |
Combination therapy with felodipine and metoprolol compared with captopril and hydrochlorothiazide. German MC Study Group.
Topics: Antihypertensive Agents; Calcium Channel Blockers; Captopril; Double-Blind Method; Drug Therapy, Combination; Felodipine; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Metoprolol; Middle Aged | 1998 |
Ambulatory 24-h blood pressure assessment of the felodipine-metoprolol combination versus amlodipine in mild to moderate hypertension. Lorraine General Physician Investigators Group.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Therapy, Combination; Felodipine; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged | 1999 |
Felodipine-metoprolol combination tablet: a valuable option to initiate antihypertensive therapy?
Topics: Administration, Oral; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Drug Therapy, Combination; Enalapril; Felodipine; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Tablets; Treatment Outcome | 1999 |
The effect of weight loss intervention on antihypertensive medication requirements in the hypertension Optimal Treatment (HOT) study.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Body Mass Index; Calcium Channel Blockers; Diet; Disease Progression; Drug Therapy, Combination; Enalapril; Felodipine; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Obesity; Risk Factors; Treatment Outcome; Weight Loss | 1999 |
The pharmacodynamic and pharmacokinetic profiles of controlled-release formulations of felodipine and metoprolol in free and fixed combinations in elderly hypertensive patients.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Circadian Rhythm; Cross-Over Studies; Delayed-Action Preparations; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Felodipine; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Placebos | 2000 |
[Prospects of use of the combined preparation logimax in patients with essential hypertension].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Calcium Channel Blockers; Delayed-Action Preparations; Drug Combinations; Felodipine; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged | 2002 |
Acute effects of vasoactive drug treatment on brachial artery reactivity.
Topics: Adult; Analysis of Variance; Brachial Artery; Cardiovascular Agents; Coronary Disease; Double-Blind Method; Enalapril; Endothelium, Vascular; Felodipine; Female; Humans; Male; Metoprolol; Models, Cardiovascular; Reference Values; Reproducibility of Results; Vasodilation | 2002 |
Felodipine-metoprolol combination tablet: maintained health-related quality of life in the presence of substantial blood pressure reduction.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Felodipine; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Patient Compliance; Quality of Life; Tablets; Treatment Outcome | 2005 |
A factorial study of combination hypertension treatment with metoprolol succinate extended release and felodipine extended release results of the Metoprolol Succinate-Felodipine Antihypertension Combination Trial (M-FACT).
Topics: Administration, Oral; Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Therapy, Combination; Felodipine; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged | 2006 |
Optimal treatment of obesity-related hypertension: the Hypertension-Obesity-Sibutramine (HOS) study.
Topics: Adult; Aged; Antihypertensive Agents; Appetite Depressants; Blood Pressure; Body Weight; Cyclobutanes; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Felodipine; Female; Humans; Hydrochlorothiazide; Hypertension; Indoles; Male; Metoprolol; Middle Aged; Obesity; Prospective Studies; Ramipril; Treatment Outcome; Verapamil | 2007 |
[Efficacy, safety and tolerance of Felodipine controlled release tablets and Felodipine controlled release tablets associated combination therapy in the treatment of mild to moderate essential hypertension in China].
Topics: Adult; Aged; Antihypertensive Agents; China; Delayed-Action Preparations; Drug Therapy, Combination; Felodipine; Female; Humans; Hydrochlorothiazide; Hypertension; Lisinopril; Male; Metoprolol; Middle Aged; Patient Compliance | 2007 |
The calcium channel blocker felodipine attenuates the positive hemodynamic effects of the beta-blocker metoprolol in severe dilated cardiomyopathy--a prospective, randomized, double-blind and placebo-controlled study with invasive hemodynamic assessment.
Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Cardiomyopathy, Dilated; Double-Blind Method; Felodipine; Female; Heart Failure; Hemodynamics; Humans; Male; Metoprolol; Middle Aged; Prospective Studies; Severity of Illness Index | 2009 |
[Effect between felodipine plus irbesartan and felodipine plus metoprolol regimen on the sexual function in young and middle-aged women with hypertension].
Topics: Adolescent; Adult; Antihypertensive Agents; Biphenyl Compounds; Felodipine; Female; Humans; Hypertension; Irbesartan; Metoprolol; Middle Aged; Prospective Studies; Sexual Dysfunction, Physiological; Tetrazoles; Young Adult | 2010 |
The effect of metoprolol alone and combined metoprolol-felodipin on the digital microcirculation of patients with primary Raynaud's syndrome.
Topics: Adult; Drug Therapy, Combination; Felodipine; Female; Fingers; Humans; Hyperemia; Hypertension; Laser-Doppler Flowmetry; Metoprolol; Microcirculation; Middle Aged; Raynaud Disease; Treatment Outcome | 2011 |
Effect of felodipine with irbesartan or metoprolol on sexual function and oxidative stress in women with essential hypertension.
Topics: Adolescent; Adult; Antihypertensive Agents; Biphenyl Compounds; Felodipine; Female; Humans; Hypertension; Irbesartan; Metoprolol; Middle Aged; Oxidative Stress; Prospective Studies; Sexuality; Tetrazoles | 2012 |
The effect of combined antihypertensive treatment (felodipine with either irbesartan or metoprolol) on erectile function: a randomized controlled trial.
Topics: Adult; Antihypertensive Agents; Biphenyl Compounds; Drug Therapy, Combination; Erectile Dysfunction; Felodipine; Humans; Hypertension; Irbesartan; Libido; Male; Metoprolol; Middle Aged; Prospective Studies; Tetrazoles; Treatment Outcome | 2013 |
54 other study(ies) available for metoprolol and felodipine
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols | 2012 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Effects of chronic felodipine treatment on renal function and morphology in SHR.
Topics: Animals; Blood Pressure; Creatinine; Drug Synergism; Felodipine; Female; Glomerulosclerosis, Focal Segmental; Hypertension; Kidney; Kidney Failure, Chronic; Metoprolol; Proteinuria; Rats; Rats, Inbred SHR; Water-Electrolyte Balance | 1992 |
Regression of left ventricular hypertrophy by felodipine or a combination of felodipine and metoprolol.
Topics: Cardiomegaly; Drug Therapy, Combination; Felodipine; Female; Humans; Male; Metoprolol; Middle Aged | 1990 |
Significance of coronary circulation in hypertensive heart disease for development and prevention of heart failure.
Topics: Adult; Animals; Cardiac Output, Low; Cardiomegaly; Coronary Circulation; Coronary Disease; Coronary Vessels; Felodipine; Humans; Hydralazine; Hypertension; Metoprolol; Nifedipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vascular Resistance | 1990 |
Acute and steady-state pharmacokinetics and antihypertensive effects of felodipine in patients with normal and impaired renal function.
Topics: Adult; Aged; Biological Availability; Blood Pressure; Felodipine; Female; Furosemide; Glomerular Filtration Rate; Half-Life; Heart Rate; Homeostasis; Humans; Hypertension; Kidney Diseases; Male; Metoprolol; Middle Aged; Time Factors | 1990 |
Baroreflex control of heart rate and renin release in SHR following administration of felodipine, an antihypertensive Ca2+ antagonist.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Felodipine; Heart Rate; Hypertension; Metoprolol; Nitrendipine; Pressoreceptors; Rats; Rats, Inbred SHR; Renin | 1987 |
Haemodynamic effects and pharmacokinetics of felodipine at rest and during exercise in hypertensive patients treated with metoprolol or atenolol.
Topics: Aged; Atenolol; Blood Pressure; Calcium Channel Blockers; Exercise; Exercise Test; Felodipine; Female; Half-Life; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Metoprolol; Middle Aged | 1989 |
The influence of antihypertensive treatment on the mesenteric arterial structure in spontaneously hypertensive rats. A morphometric study.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Felodipine; Heart Rate; Male; Mesenteric Arteries; Metoprolol; Muscle, Smooth, Vascular; Nitrendipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1989 |
The effects of combining felodipine and metoprolol in moderate to severe hypertension--a one year study.
Topics: Adult; Aged; Antihypertensive Agents; Drug Therapy, Combination; Felodipine; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Nitrendipine | 1988 |
Effects of felodipine and metoprolol on blood pressure, plasma renin, angiotensin II, aldosterone and catecholamines in hypertensive patients.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Blood Pressure; Catecholamines; Electrocardiography; Felodipine; Humans; Hypertension; Male; Metoprolol; Nitrendipine; Renin; Time Factors | 1987 |
Influence of antihypertensive treatment on basal cerebral arteries in spontaneously hypertensive rats. A morphometric study.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Cerebral Arteries; Drug Therapy, Combination; Felodipine; Heart Rate; Hypertension; Metoprolol; Nitrendipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1988 |
Structural and functional adaptations within the myocardium and coronary vessels after antihypertensive therapy in spontaneously hypertensive rats.
Topics: Animals; Coronary Circulation; Coronary Vessels; Felodipine; Hypertension; Metoprolol; Myocardium; Nitrendipine; Oxygen Consumption; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Vascular Resistance | 1986 |
Does sympathectomy or antihypertensive treatment affect the morphometry of basal cerebral arteries in spontaneously hypertensive rats?
Topics: Age Factors; Animals; Blood Pressure; Cerebral Arteries; Felodipine; Ganglia, Sympathetic; Hypertension; Metoprolol; Nitrendipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sympathectomy | 1986 |
Acute haemodynamic and humoral responses to felodipine and metoprolol in mild hypertension.
Topics: Adult; Aldosterone; Antihypertensive Agents; Calcium Channel Blockers; Catecholamines; Drug Therapy, Combination; Felodipine; Hemodynamics; Humans; Hypertension; Male; Metoprolol; Nitrendipine; Pulmonary Circulation; Renin-Angiotensin System; Vasodilator Agents | 1987 |
The use of Doppler echocardiography to assess the acute haemodynamic response to felodipine and metoprolol in hypertensive patients.
Topics: Adult; Antihypertensive Agents; Cardiac Output; Echocardiography; Felodipine; Hemodynamics; Humans; Hypertension; Male; Metoprolol; Nitrendipine; Stroke Volume; Vascular Resistance | 1987 |
The influence of antihypertensive treatment on the renal arterial structure in spontaneously hypertensive rats. A morphometric study.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Felodipine; Heart Rate; Hypertension; Male; Metoprolol; Nitrendipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Artery | 1987 |
Influence of long-term antihypertensive therapy on cardiac function, coronary flow and myocardial oxygen consumption in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Coronary Circulation; Felodipine; Heart; Heart Rate; Hypertension; Male; Metoprolol; Myocardium; Nifedipine; Oxygen Consumption; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Stroke Volume; Time Factors; Vascular Resistance | 1986 |
Effect of felodipine and metoprolol on muscle and skin arteries in hypertensive patients.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Felodipine; Female; Heart Rate; Humans; Hyperemia; Hypertension; Male; Metoprolol; Middle Aged; Muscle, Smooth, Vascular; Muscles; Nifedipine; Physical Exertion; Posture; Regional Blood Flow; Skin; Vascular Resistance | 1985 |
Electrophysiological effects of felodipine in combination with metoprolol.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Antihypertensive Agents; Arrhythmias, Cardiac; Blood Pressure; Drug Synergism; Electrocardiography; Electrophysiology; Felodipine; Female; Heart Conduction System; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Nifedipine; Purkinje Fibers; Vasodilator Agents | 1985 |
Regression of structural cardiovascular changes by antihypertensive therapy in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Cardiovascular System; Circadian Rhythm; Felodipine; Heart Rate; Hypertension; Methyldopa; Metoprolol; Nifedipine; Rats; Rats, Inbred SHR; Time Factors | 1984 |
Time-dependent efficacy of antihypertensive agents in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Circadian Rhythm; Clonidine; Felodipine; Heart Rate; Hypertension; Labetalol; Male; Metoprolol; Oxazoles; Prazosin; Propanolamines; Propranolol; Rats; Rats, Inbred SHR; Rilmenidine; Thiophenes | 1993 |
Design and pharmacokinetics of Logimax, a new extended-release combination tablet of felodipine and metoprolol.
Topics: Adult; Aged; Aging; Biological Availability; Delayed-Action Preparations; Drug Combinations; Felodipine; Food; Humans; Metoprolol | 1993 |
Effects of antihypertensive therapy on platelet cytosolic calcium responses to low density lipoprotein cholesterol.
Topics: Aged; Aged, 80 and over; Blood Platelets; Calcium; Cholesterol, LDL; Cytosol; Diltiazem; Drug Therapy, Combination; Enalapril; Felodipine; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Prospective Studies | 1996 |
Antihypertensive drugs reduce noradrenaline-induced hypertrophy of cultured myocardial cells.
Topics: Animals; Antihypertensive Agents; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Felodipine; Heart; Leucine; Metoprolol; Myocardium; Norepinephrine; Propranolol; Protein Biosynthesis; Rats | 1996 |
Cardiovascular and renal effects of the combination of felodipine and metoprolol during a high-salt and a moderate-salt diet in spontaneously hypertensive rats.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Calcium Channel Blockers; Drug Therapy, Combination; Felodipine; Heart Rate; Hypertension; Hypertrophy; Hypertrophy, Left Ventricular; In Vitro Techniques; Kidney; Male; Mesenteric Arteries; Metoprolol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium Chloride, Dietary; Vasodilator Agents | 1997 |
Bioequivalence, pharmacokinetic and pharmacodynamic response to combined extended release formulations of felodipine and metoprolol in healthy volunteers.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Area Under Curve; Blood Pressure; Calcium Channel Blockers; Delayed-Action Preparations; Drug Interactions; Felodipine; Female; Heart Rate; Humans; Male; Metabolic Clearance Rate; Metoprolol; Middle Aged; Therapeutic Equivalency | 1997 |
[Stable angina pectoris: what is the role of calcium antagonists?].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Atenolol; Calcium Channel Blockers; Clinical Trials as Topic; Dihydropyridines; Diltiazem; Drug Therapy, Combination; Felodipine; Humans; Metoprolol; Multicenter Studies as Topic; Nifedipine; Randomized Controlled Trials as Topic; Verapamil | 1997 |
Cost-effectiveness of felodipine-metoprolol (Logimax) and enalapril in the treatment of hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Cost-Benefit Analysis; Drug Combinations; Enalapril; Felodipine; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Retrospective Studies; Sweden | 1998 |
[Preparation of transdermal drug delivery system of felodipine-metoprolol and its bioavailability in rabbits].
Topics: Administration, Cutaneous; Animals; Antihypertensive Agents; Area Under Curve; Azepines; Biological Availability; Cyclohexanols; Delayed-Action Preparations; Drug Delivery Systems; Drug Stability; Eucalyptol; Felodipine; Female; Male; Metoprolol; Monoterpenes; Propylene Glycols; Rabbits; Skin Absorption | 2007 |
Effects of antihypertensive therapy on female sexual dysfunction: clinically meaningful?
Topics: Antihypertensive Agents; Biphenyl Compounds; Felodipine; Female; Humans; Hypertension; Metoprolol; Oxidative Stress; Sexuality; Tetrazoles | 2012 |
Validated LC-ESI-MS/MS method for simultaneous quantitation of felodipine and metoprolol in rat plasma: application to a pharmacokinetic study in rats.
Topics: Acetonitriles; Animals; Chromatography, High Pressure Liquid; Drug Stability; Felodipine; Formates; Linear Models; Male; Metoprolol; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2013 |
Combined antihypertensive therapy and sexual dysfunction: terra incognita.
Topics: Antihypertensive Agents; Biphenyl Compounds; Erectile Dysfunction; Felodipine; Humans; Irbesartan; Male; Metoprolol; Tetrazoles | 2013 |
Re: the effect of combined antihypertensive treatment (felodipine with either irbesartan or metoprolol) on erectile function: a randomized controlled trial.
Topics: Antihypertensive Agents; Biphenyl Compounds; Erectile Dysfunction; Felodipine; Humans; Male; Metoprolol; Tetrazoles | 2014 |
Development and validation of TLC-densitometric method for simultaneous determination of two binary antihypertensive mixtures containing felodipine in fixed dose combinations.
Topics: Antihypertensive Agents; Chromatography, Thin Layer; Densitometry; Drug Stability; Felodipine; Limit of Detection; Linear Models; Metoprolol; Ramipril; Reproducibility of Results | 2016 |
Synchronous delivery of felodipine and metoprolol tartrate using monolithic osmotic pump technology.
Topics: Animals; Antihypertensive Agents; Delayed-Action Preparations; Dogs; Drug Delivery Systems; Felodipine; Humans; Metoprolol; Osmosis; Solubility; Tablets | 2016 |
Simultaneous Determination of Felodipine and Metoprolol in Beagle Dog Plasma by Online SPE-LC-MS/MS and Its Application in a Pharmacokinetic Study.
Topics: Animals; Chromatography, Liquid; Dogs; Felodipine; Internet; Male; Metoprolol; Solid Phase Extraction; Tandem Mass Spectrometry | 2017 |
Development and Validation of RP-HPLC and an Ecofriendly HPTLC Method for Simultaneous Determination of Felodipine and Metoprolol Succinate, and their Major Metabolites in Human Spiked Plasma.
Topics: Chromatography, High Pressure Liquid; Felodipine; Humans; Metoprolol; Reproducibility of Results; Tablets | 2020 |
THE NITROSAMINE CONTAMINATION IN BETA BLOCKERS (BISOPROLOL/METOPROLOL), ACE INHIBITORS (LISINOPRIL/PERINDOPRIL), THIAZIDES DIURETICS (HCT), CALCIUM CHANNEL BLOCKERS (AMLODIPINE/FELODIPINE), SARTANS (CANDESARTAN) AND ТHE SUBSEQUENT SKIN CANCER DEVELOPMENT
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Bisoprolol; Calcium; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Felodipine; Humans; Lisinopril; Melanoma; Metoprolol; Nitrosamines; Perindopril; Prospective Studies; Skin Neoplasms; Sodium Chloride Symporter Inhibitors; Thiazides | 2023 |