metoprolol and amiloride

metoprolol has been researched along with amiloride in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19905 (27.78)18.7374
1990's3 (16.67)18.2507
2000's6 (33.33)29.6817
2010's4 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Faller, B; Wohnsland, F1
Artursson, P; Luthman, K; Norinder, U; Stenberg, P1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Avdeef, A; Tam, KY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Simpson, FO; Waal-Manning, HJ1
Dahlöf, B; Ekbom, T; Hansson, L; Lindholm, LH; Scherstén, B; Wester, PO1
Angioni, L; Botta, G; Capra, A; Leonetti, G; Mazzola, C; Pasotti, C; Vaccarella, A; Zanchetti, A2
Dahlöf, B; Hansson, L; Lindholm, L; Råstam, L; Scherstén, B; Wester, PO1
Hardarson, T; Ragnarsson, J; Snorrason, SP1
Thomas, JP; Thomson, WH1
Polonský, J; Sádecká, J1

Reviews

1 review(s) available for metoprolol and amiloride

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

7 trial(s) available for metoprolol and amiloride

ArticleYear
One year follow-up of hyperuricaemic hypertensive patients treated with tienilic acid or a diuretic with or without uric acid-lowering drugs.
    Clinical science (London, England : 1979), 1979, Volume: 57 Suppl 5

    Topics: Alkaline Phosphatase; Amiloride; Aspartate Aminotransferases; Bilirubin; Blood Pressure; Clinical Trials as Topic; Cyclopenthiazide; Diuretics; Female; Follow-Up Studies; Glycolates; Heart Rate; Humans; Hypertension; Male; Metoprolol; Middle Aged; Propanolamines; Pyrazines; Sodium Chloride Symporter Inhibitors; Ticrynafen; Uric Acid

1979
Antihypertensive efficacy and side effects of three beta-blockers and a diuretic in elderly hypertensives: a report from the STOP-Hypertension study.
    Journal of hypertension, 1992, Volume: 10, Issue:12

    Topics: Aged; Aged, 80 and over; Amiloride; Atenolol; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Metoprolol; Pindolol; Prospective Studies; Treatment Outcome

1992
Treatment of hypertension in the elderly: effects on blood pressure, heart rate, and physical fitness.
    The American journal of medicine, 1991, Volume: 90, Issue:3A

    Topics: Aged; Amiloride; Antihypertensive Agents; Blood Pressure; Captopril; Female; Heart Rate; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Male; Metoprolol; Middle Aged; Physical Endurance; Physical Fitness

1991
Antihypertensive efficacy and influence on physical activity of three different treatments in elderly hypertensive patients.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1989, Volume: 7, Issue:6

    Topics: Aged; Amiloride; Antihypertensive Agents; Captopril; Drug Evaluation; Drug Therapy, Combination; Drug Tolerance; Female; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Male; Metoprolol; Middle Aged; Physical Endurance

1989
Swedish trial in old patients with hypertension. A prospective multicentre study in Swedish primary health care.
    Scandinavian journal of primary health care, 1986, Volume: 4, Issue:3

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Amiloride; Atenolol; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Metoprolol; Pindolol; Prospective Studies; Random Allocation; Sweden

1986
Ventricular dysrhythmias in middle-aged hypertensive men treated either with a diuretic agent or a beta-blocker.
    Acta medica Scandinavica, 1987, Volume: 221, Issue:2

    Topics: Aged; Amiloride; Arrhythmias, Cardiac; Bendroflumethiazide; Clinical Trials as Topic; Drug Combinations; Heart Ventricles; Humans; Hydrochlorothiazide; Hypertension; Magnesium; Male; Metoprolol; Middle Aged; Potassium; Propranolol; Random Allocation

1987
Comparison of thiazides and amiloride in treatment of moderate hypertension.
    British medical journal (Clinical research ed.), 1983, Jun-25, Volume: 286, Issue:6383

    Topics: Adult; Aged; Amiloride; Drug Combinations; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Metoprolol; Middle Aged; Potassium; Pyrazines

1983

Other Studies

10 other study(ies) available for metoprolol and amiloride

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.
    Journal of medicinal chemistry, 2001, Mar-15, Volume: 44, Issue:6

    Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water

2001
Experimental and computational screening models for the prediction of intestinal drug absorption.
    Journal of medicinal chemistry, 2001, Jun-07, Volume: 44, Issue:12

    Topics: Biological Transport; Carbon Radioisotopes; Cell Line; Cell Membrane; Cell Membrane Permeability; Ciprofloxacin; Computational Biology; Drug Design; Foscarnet; Humans; Hydrogen Bonding; Intestinal Absorption; Intestinal Mucosa; Lactulose; Mannitol; Models, Biological; Raffinose; Surface Properties; Tritium; Verapamil

2001
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis

2010
Determination of some cardiovascular drugs in serum and urine by capillary isotachophoresis.
    Journal of chromatography. A, 1996, May-31, Volume: 735, Issue:1-2

    Topics: Adrenergic beta-Antagonists; Amiloride; Cardiovascular Agents; Electrophoresis, Capillary; Furosemide; Humans; Hydrogen-Ion Concentration; Labetalol; Metipranolol; Metoprolol; Reproducibility of Results

1996