Page last updated: 2024-08-22

metoprine and trimethoprim

metoprine has been researched along with trimethoprim in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19903 (42.86)18.7374
1990's3 (42.86)18.2507
2000's0 (0.00)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Coats, EA; Genther, CS; Hansch, C; Selassie, CD; Strong, CD1
Andrews, PR; Craik, DJ; Martin, JL1
Dias, CB; Hansch, C; Khwaja, TA; Pentecost, S; Selassie, CD1
Baccanari, DP; Boytos, CM; Caddell, JM; Comley, JC; Friedman, HS; Hunter, RN; Jones, ML; Joyner, SS; Knick, V; Kuyper, LF; Rudolph, SK; Stables, JN; Tansik, RL; Wilson, HR1
Boesche, M; Crowther, GJ; Dasari, KS; Drewes, G; El Bakkouri, M; Fox, AM; Ghidelli-Disse, S; He, P; Hillesland, HK; Hui, R; Jones, JC; Keyloun, KR; Krahn, MM; Lafuente-Monasterio, MJ; Leonard, SE; Leroy, D; Maly, DJ; Mo, JS; Ojo, KK; Reid, MC; Rivas, KL; Van Voorhis, WC1
Gorrod, JW; Watkins, PJ1
Assaraf, YG; Slotky, JI1

Other Studies

7 other study(ies) available for metoprine and trimethoprim

ArticleYear
Quantitative structure-activity relationship of antifolate inhibition of bacteria cell cultures resistant and sensitive to methotrexate.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:12

    Topics: Biological Transport, Active; Chemical Phenomena; Chemistry; Drug Resistance, Microbial; Escherichia coli; Folic Acid Antagonists; Lacticaseibacillus casei; Mathematics; Methotrexate; Pyrimethamine; Pyrimidines; Structure-Activity Relationship; Triazines

1985
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Comparative structure-activity relationships of antifolate triazines inhibiting murine tumor cells sensitive and resistant to methotrexate.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:3

    Topics: Animals; Chemical Phenomena; Chemistry, Physical; Chickens; Drug Resistance; Folic Acid Antagonists; Humans; Leukemia L5178; Leukemia, Experimental; Mathematics; Methotrexate; Mice; Structure-Activity Relationship; Triazines

1984
High-affinity inhibitors of dihydrofolate reductase: antimicrobial and anticancer activities of 7,8-dialkyl-1,3-diaminopyrrolo[3,2-f]quinazolines with small molecular size.
    Journal of medicinal chemistry, 1996, Feb-16, Volume: 39, Issue:4

    Topics: Animals; Anti-Infective Agents; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain Neoplasms; Candidiasis; Cell Division; Cell Line; Crystallography, X-Ray; Drug Design; Drug Resistance, Multiple; Enzyme Inhibitors; Folic Acid Antagonists; Humans; Lung Neoplasms; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Mice, Nude; Mice, SCID; Models, Molecular; Molecular Conformation; Molecular Structure; Molecular Weight; Pneumonia, Pneumocystis; Protein Structure, Secondary; Quinazolines; Structure-Activity Relationship; Toxoplasma; Tumor Cells, Cultured

1996
Biochemical Screening of Five Protein Kinases from Plasmodium falciparum against 14,000 Cell-Active Compounds.
    PloS one, 2016, Volume: 11, Issue:3

    Topics: Antimalarials; Calcium; Cell Line, Tumor; Hep G2 Cells; Humans; Malaria, Falciparum; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase Kinases; Plasmodium falciparum; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protozoan Proteins

2016
Determination of isomeric N-oxide metabolites of some substituted 2,4-diaminopyrimidines by reversed-phase ion-pair high-performance liquid chromatography.
    Journal of chromatography, 1993, Jun-23, Volume: 616, Issue:1

    Topics: Animals; Antineoplastic Agents; Chromatography, High Pressure Liquid; Cricetinae; Dioctyl Sulfosuccinic Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Indicators and Reagents; Isomerism; Microsomes, Liver; Oxides; Pyrimethamine; Pyrimidines; Surface-Active Agents; Trimethoprim

1993
Characterization of a lipophilic antifolate resistance provoked by treatment of mammalian cells with the antiparasitic agent pyrimethamine.
    The Journal of biological chemistry, 1993, Feb-25, Volume: 268, Issue:6

    Topics: Animals; Cell Survival; CHO Cells; Cricetinae; Drug Resistance; Flow Cytometry; Folic Acid Antagonists; Leucovorin; Pyrimethamine; RNA, Messenger; Tetrahydrofolate Dehydrogenase; Trimethoprim

1993