Page last updated: 2024-08-22

metoprine and etoprine

metoprine has been researched along with etoprine in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19906 (85.71)18.7374
1990's1 (14.29)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hansch, C; Khwaja, TA; Selassie, CD1
Levin, VA1
Brown, O; Fyfe, MJ; Laszlo, J; Lee, L; Swedwick, D1
Cavallito, JC; Nichol, CA; Sigel, CW; Woolley, JL1
Levin, EM; Levin, VA; Meyer, RB1
Ganeshaguru, K; Hoffbrand, AV1
Bigner, DD; Nichol, CA; Serano, RD; Sigel, CW1

Other Studies

7 other study(ies) available for metoprine and etoprine

ArticleYear
Structure-activity relationships of antineoplastic agents in multidrug resistance.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:7

    Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Dactinomycin; Drug Resistance; Leukemia L1210; Mice; Regression Analysis; Structure-Activity Relationship; Tumor Cells, Cultured

1990
Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeability.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:6

    Topics: Animals; Blood-Brain Barrier; Brain; Capillary Permeability; Male; Models, Biological; Molecular Weight; Rats; Rats, Inbred F344; Solubility; Structure-Activity Relationship

1980
Comparison of metoprine (DDMP) and etoprine (DDEP) by measuring the inhibition of deoxyuridine incorporation into the DNA of human leukemic cells 1,2,3.
    Cancer treatment reports, 1978, Volume: 62, Issue:3

    Topics: Antineoplastic Agents; Cells, Cultured; Deoxyuridine; Depression, Chemical; DNA, Neoplasm; Humans; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Pyrimethamine; Time Factors

1978
Lipid-soluble diaminopyrimidine inhibitors of dihydrofolate reductase.
    Cancer treatment reports, 1977, Volume: 61, Issue:4

    Topics: Administration, Oral; Animals; Brain; Brain Neoplasms; Dogs; Folic Acid; Folic Acid Antagonists; Half-Life; Humans; Leucovorin; Lipid Metabolism; Male; Models, Biological; Pyrimethamine; Pyrimidines; Rats; Solubility; Species Specificity

1977
Quantitative high-pressure liquid chromatographic procedure for the determination of plasma and tissue levels of 2,4-diamino-5-(3,4-dichlorophenyl)-6-methylpyrimidine (metoprine) and its application to the measurement of brain capillary permeability coeff
    Journal of chromatography, 1978, Aug-21, Volume: 156, Issue:1

    Topics: Animals; Antineoplastic Agents; Brain; Capillary Permeability; Chromatography, High Pressure Liquid; Pyrimethamine; Rats

1978
Effects of DDMP and DDEP on the deoxyribonucleoside triphosphate concentrations in human cells.
    Biochemical pharmacology, 1977, Mar-15, Volume: 26, Issue:6

    Topics: Chlorobenzenes; Deoxyribonucleotides; Humans; Kinetics; Lectins; Lymphocyte Activation; Lymphocytes; Methotrexate; Pyrimethamine; Pyrimidines; Tetrahydrofolates

1977
Evaluation of the lipid-soluble diaminopyrimidines, metoprine and etoprine, in the avian sarcoma virus rat glioma model.
    Cancer treatment reports, 1982, Volume: 66, Issue:1

    Topics: Animals; Antineoplastic Agents; Avian Sarcoma Viruses; Carmustine; Drug Therapy, Combination; Glioma; Lipids; Neoplasms, Experimental; Pyrimethamine; Rats; Rats, Inbred F344; Solubility; Tissue Distribution

1982