Page last updated: 2024-08-22

metoprine and deoxyuridine

metoprine has been researched along with deoxyuridine in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19908 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brown, O; Fyfe, MJ; Laszlo, J; Lee, L; Swedwick, D1
Brown, OE; Frazer, T; Kutler, M; Laszlo, J; Sedwick, WD1
Brown, OE; Frazer, TA; Fyfe, MJ; Kutler, M; Laszlo, J; Sedwick, WD1
Galivan, J; Nimec, Z; Rhee, M1
Brown, OE; Fyfe, MJ; Laszlo, J; Sedwick, WD1
Browman, GP; Calvert, AH; Harrap, KR; Hart, LI; Taylor, GA1
Brown, OE; Hamrell, M; Laszlo, J; Sedwick, WD1
Laszlo, J; Sedwick, WD1

Other Studies

8 other study(ies) available for metoprine and deoxyuridine

ArticleYear
Comparison of metoprine (DDMP) and etoprine (DDEP) by measuring the inhibition of deoxyuridine incorporation into the DNA of human leukemic cells 1,2,3.
    Cancer treatment reports, 1978, Volume: 62, Issue:3

    Topics: Antineoplastic Agents; Cells, Cultured; Deoxyuridine; Depression, Chemical; DNA, Neoplasm; Humans; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Pyrimethamine; Time Factors

1978
New dose-time relationships of folate antagonists to sustain inhibition of human lymphoblasts and leukemic cells in vitro.
    Cancer research, 1979, Volume: 39, Issue:9

    Topics: Cell Line; Cell Survival; Deoxyuridine; Dose-Response Relationship, Drug; Folic Acid Antagonists; Humans; Leucovorin; Leukemia; Methotrexate; Pyrimethamine; Time Factors

1979
Deoxyuridine incorporation as a useful measure of methotrexate and metoprine uptake and metabolic effectiveness.
    Molecular pharmacology, 1979, Volume: 16, Issue:2

    Topics: Deoxyuridine; Folic Acid Antagonists; Humans; Kinetics; Methotrexate; Pyrimethamine; Time Factors

1979
Synergistic growth inhibition of rat hepatoma cells exposed in vitro to N10-propargyl-5,8-dideazafolate with methotrexate or the lipophilic antifolates trimetrexate or metoprine.
    Cancer research, 1987, Oct-15, Volume: 47, Issue:20

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Deoxyuridine; Folic Acid; Folic Acid Antagonists; Liver Neoplasms, Experimental; Methotrexate; Pyrimethamine; Quinazolines; Rats; Thymidine; Thymidylate Synthase; Trimetrexate

1987
Human plasma and amino acids as moderators of uptake and metabolic consequences of antifolates in WIL-2 and human leukemia cells.
    Journal of the National Cancer Institute, 1981, Volume: 66, Issue:3

    Topics: Amino Acids; Blood; Cell Line; Culture Media; Deoxyuridine; Folic Acid Antagonists; Glutamine; Humans; Kinetics; Leukemia; Lymphocytes; Methotrexate; Pyrimethamine

1981
The intracellular mechanism of action of metoprine (DDMP).
    European journal of cancer, 1980, Volume: 16, Issue:12

    Topics: Animals; Cell Survival; Cells, Cultured; Deoxyuridine; Dose-Response Relationship, Drug; Drug Resistance; Folic Acid Antagonists; Leucovorin; Leukemia L1210; Methotrexate; Mice; Purines; Pyrimethamine; Pyrimidines; Thymidine

1980
Toxicity of methotrexate and metoprine in a dihydrofolate reductase gene-amplified mouse cell line.
    Molecular pharmacology, 1981, Volume: 20, Issue:3

    Topics: Cell Line; Clone Cells; Deoxyuridine; Folic Acid Antagonists; Kinetics; Methotrexate; Phosphorus Radioisotopes; Pyrimethamine; Tetrahydrofolate Dehydrogenase

1981
An antifolate-induced lesion in newly synthesized DNA.
    Advances in enzyme regulation, 1980, Volume: 19

    Topics: Cell Line; Cell Survival; Deoxyuridine; DNA; Folic Acid Antagonists; Humans; Methotrexate; Molecular Weight; Pyrimethamine; Thymidine

1980