metolazone and bumetanide

metolazone has been researched along with bumetanide in 14 studies

Research

Studies (14)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (14.29)	18.7374
1990's	0 (0.00)	18.2507
2000's	5 (35.71)	29.6817
2010's	6 (42.86)	24.3611
2020's	1 (7.14)	2.80

Authors

Authors	Studies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Cecchi, A; Scozzafava, A; Supuran, CT; Temperini, C	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Campillo, NE; Guerra, A; Páez, JA	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Anderson, SA; Brater, DC; Pressley, RH	1
Galatius, S; Gustafsson, F; Hildebrandt, PR; Rosenberg, J	1
Elkayam, U; Han, SY; Hshieh, S; Hyderi, AF; Jeng, AI; Kim, BJ; Konopka, E; Lou, M; Ng, TM; Phan, DH; Tsuji, Y	1
Hildebrandt, KR; Kemnic, T; Srivastava, S	1

Reviews

1 review(s) available for metolazone and bumetanide

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

2 trial(s) available for metolazone and bumetanide

Article	Year
New diuretics - bumetanide and metolazone. Drug and therapeutics bulletin, 1974, Jun-21, Volume: 12, Issue:13 Topics: Bumetanide; Clinical Trials as Topic; Diuretics; Edema; Humans; Metolazone	1974
Combination therapy with metolazone and loop diuretics in outpatients with refractory heart failure: an observational study and review of the literature. Cardiovascular drugs and therapy, 2005, Volume: 19, Issue:4 Topics: Aged; Aged, 80 and over; Blood Pressure; Body Weight; Bumetanide; Diuretics; Drug Therapy, Combination; Female; Furosemide; Heart Failure; Humans; Male; Metolazone; Outpatients; Potassium; Randomized Controlled Trials as Topic; Sodium; Water-Electrolyte Balance	2005

Article

Year

New diuretics - bumetanide and metolazone.

Drug and therapeutics bulletin, 1974, Jun-21, Volume: 12, Issue:13

Topics: Bumetanide; Clinical Trials as Topic; Diuretics; Edema; Humans; Metolazone

1974

Combination therapy with metolazone and loop diuretics in outpatients with refractory heart failure: an observational study and review of the literature.

Cardiovascular drugs and therapy, 2005, Volume: 19, Issue:4

Topics: Aged; Aged, 80 and over; Blood Pressure; Body Weight; Bumetanide; Diuretics; Drug Therapy, Combination; Female; Furosemide; Heart Failure; Humans; Male; Metolazone; Outpatients; Potassium; Randomized Controlled Trials as Topic; Sodium; Water-Electrolyte Balance

2005

Other Studies

11 other study(ies) available for metolazone and bumetanide

Article	Year
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Carbonic anhydrase inhibitors. Interaction of indapamide and related diuretics with 12 mammalian isozymes and X-ray crystallographic studies for the indapamide-isozyme II adduct. Bioorganic & medicinal chemistry letters, 2008, Apr-15, Volume: 18, Issue:8 Topics: Animals; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Computer Simulation; Crystallography, X-Ray; Humans; Indapamide; Isoenzymes; Mice; Models, Molecular; Molecular Structure	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Mechanisms of the synergistic combination of metolazone and bumetanide. The Journal of pharmacology and experimental therapeutics, 1985, Volume: 233, Issue:1 Topics: Adult; Biological Transport; Bumetanide; Chlorides; Diuretics; Drug Synergism; Humans; Kidney Tubules; Male; Metolazone; Phosphates; Sodium; Water-Electrolyte Balance	1985
Comparison of bumetanide- and metolazone-based diuretic regimens to furosemide in acute heart failure. Journal of cardiovascular pharmacology and therapeutics, 2013, Volume: 18, Issue:4 Topics: Acute Disease; Adult; Aged; Blood Urea Nitrogen; Bumetanide; Cohort Studies; Diuretics; Drug Therapy, Combination; Female; Furosemide; Heart Failure; Humans; Hyponatremia; Incidence; Male; Metolazone; Middle Aged; Regression Analysis; Retrospective Studies; Treatment Outcome; Urine	2013
BRASH syndrome. BMJ case reports, 2020, Feb-23, Volume: 13, Issue:2 Topics: Antihypertensive Agents; Atrioventricular Block; Bradycardia; Bumetanide; Carvedilol; Female; Humans; Hyperkalemia; Metolazone; Middle Aged; Renal Insufficiency; Shock; Syndrome; Vasoconstrictor Agents	2020