metoclopramide and theophylline

metoclopramide has been researched along with theophylline in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19903 (13.64)18.7374
1990's2 (9.09)18.2507
2000's10 (45.45)29.6817
2010's7 (31.82)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, HL; Metz, G; Pindell, MH1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Hamilton, JT; Okwuasaba, FK1
Grimbeek, RJ; Meyer, EC; Moncrieff, J; Snyman, JR; Sommers, DK; Van Wyk, M1
Henderson, A; Pond, SM; Wright, DM1
Bryson, JC; Dukes, GE; Heizer, WD; Kirby, MG; Powell, JR1
Bellon, A; Chacko, RC; Coverdale, JH; Perez-Garcia, G1
Baszyńska-Wachowiak, H; Buczkowski, P; Jemielity, M; Pawłowska, M; Perek, B; Straburzyńska-Migaj, E; Urbanowicz, T1

Reviews

2 review(s) available for metoclopramide and theophylline

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Seizures associated with levofloxacin: case presentation and literature review.
    European journal of clinical pharmacology, 2009, Volume: 65, Issue:10

    Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteremia; Cytochrome P-450 CYP1A2; Dopamine Antagonists; Drug Administration Schedule; Drug Synergism; Female; Humans; Klebsiella Infections; Levofloxacin; Male; Metoclopramide; Mianserin; Middle Aged; Mirtazapine; Ofloxacin; Phosphodiesterase Inhibitors; Seizures; Theophylline

2009

Trials

2 trial(s) available for metoclopramide and theophylline

ArticleYear
The influence of codeine, propantheline and metoclopramide on small bowel transit and theophylline absorption from a sustained-release formulation.
    British journal of clinical pharmacology, 1992, Volume: 33, Issue:3

    Topics: Adult; Codeine; Female; Gastrointestinal Transit; Humans; Male; Metoclopramide; Propantheline; Reference Values; Theophylline

1992
Effect of altering small bowel transit time on sustained release theophylline absorption.
    Journal of clinical pharmacology, 1989, Volume: 29, Issue:8

    Topics: Adult; Delayed-Action Preparations; Gastrointestinal Transit; Humans; Intestinal Absorption; Intestine, Small; Loperamide; Male; Metoclopramide; Theophylline

1989

Other Studies

18 other study(ies) available for metoclopramide and theophylline

ArticleYear
Cloxacepride and related compounds: a new series of orally active antiallergic compounds.
    Journal of medicinal chemistry, 1983, Volume: 26, Issue:7

    Topics: Administration, Oral; Anaphylaxis; Animals; Benzamides; Female; Histamine H1 Antagonists; Indicators and Reagents; Rats; Structure-Activity Relationship; Theophylline

1983
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
The effect of metoclopramide on inhibition induced by purine nucleotides, noradrenaline, and theophylline ethylenediamine on intestinal muscle and on peristalsis in vitro.
    Canadian journal of physiology and pharmacology, 1975, Volume: 53, Issue:5

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Colon; Duodenum; Ethylenediamines; Gastrointestinal Motility; Guinea Pigs; Ileum; Male; Metoclopramide; Muscle, Smooth; Norepinephrine; Organ Specificity; Peristalsis; Purine Nucleotides; Rabbits; Rats; Species Specificity; Theophylline

1975
Management of theophylline overdose patients in the intensive care unit.
    Anaesthesia and intensive care, 1992, Volume: 20, Issue:1

    Topics: Absorption; Adolescent; Adult; Arrhythmias, Cardiac; Charcoal; Critical Care; Drug Overdose; Female; Gastric Lavage; Hemoperfusion; Humans; Length of Stay; Male; Metoclopramide; Middle Aged; Potassium; Retrospective Studies; Seizures; Survival Rate; Theophylline; Vomiting

1992
Seizures after heart transplantation--two cases of non-immunosuppressant drug interactions in young patients.
    Annals of transplantation, 2014, Aug-22, Volume: 19

    Topics: Adult; Antiemetics; Bradycardia; Brain; Dopamine D2 Receptor Antagonists; Drug Interactions; Epilepsy, Tonic-Clonic; Female; Heart Transplantation; Humans; Magnetic Resonance Imaging; Male; Metoclopramide; Phosphodiesterase Inhibitors; Postoperative Complications; Theophylline

2014