metoclopramide has been researched along with prochlorperazine in 91 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (28.57) | 18.7374 |
| 1990's | 23 (25.27) | 18.2507 |
| 2000's | 10 (10.99) | 29.6817 |
| 2010's | 26 (28.57) | 24.3611 |
| 2020's | 6 (6.59) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Ekert, H; Jurk, IH; Loughnan, P; Mobilia, J; Waters, KD | 1 |
| Klepp, O | 1 |
| Stoddart, JC | 1 |
| de La Tour, J; Debray, C; Rozé, C; Souchard, M; Vaille, C | 1 |
| Bishop, JF; Buchanan, L; Cooper, IA; Laidlaw, C; Matthews, J; Olver, IN; Smith, R; Wolf, M | 1 |
| Rodgers, C | 1 |
| Beaulieu, R; Courchesne, Y; Latreille, J; Letendre, F; Lorange, A; Louvet, C; Monte, M; Neemeh, JA; Pretty, HM | 1 |
| Eisendrath, SJ; Ferrando, SJ | 1 |
| Akhtar, SS; Bano, ZA; Bhat, GM; Bhat, MA | 1 |
| Factor, SA; Matthews, MK | 1 |
| Christensen, CW; Deppe, G; Malone, JM; Malviya, VK; Yashinsky, D | 1 |
| Bateman, DN; Boys, R; Darling, WM; Rawlins, MD | 1 |
| Alroe, C; Bowen, P | 1 |
| Adams, L; Bradley, CJ; Cunningham, D; Forrest, GJ; Harding, M; Hutcheon, AW; Kaye, SB; Kerr, DJ; Sneddon, M; Soukop, M | 1 |
| Murakami, M; Ota, K | 1 |
| Newton-John, H | 1 |
| Tokola, RA | 1 |
| Eguchi, K; Inoue, I; Nino, S; Saijo, N; Sakurai, M; Sasaki, Y; Shinkai, T; Suemasu, K; Tamura, T; Umehara, H | 1 |
| Ackland, S; Bishop, JF; Cooper, IA; Hillcoat, BL; Matthews, JP; Morton, C; Scott, K; Wolf, M; Yuen, K | 1 |
| Laghari, NA; Lambourne, A; Van den Berg, AA; Yazji, NS | 1 |
| Lambourne, A; van den Berg, AA | 1 |
| Aasebø, U; Myhr, K | 1 |
| Chan, KK; Luesley, DM; Terry, PB | 1 |
| Bertrand, M; Browning, S; Carr, BI; Doroshow, JH; Hill, LR; Presant, C; Pulone, B | 1 |
| Ward, HW | 1 |
| Bakowski, MT | 1 |
| Boublik, JH; Funder, JW | 1 |
| Gabryś, K; Kotlarek-Haus, S; Orzechowska-Juzwenko, K | 1 |
| Bruera, ED; Chacón, RD; Roca, E | 1 |
| Chan, SC; Lo, JR; Wong, KC | 1 |
| Ayers, JL; Dawson, KP | 1 |
| Bordin, LA; Braun, DW; Braun, TJ; Gralla, RJ; Itri, LM; Kelsen, DP; Pisko, SE; Squillante, AE; Young, CW | 1 |
| Coppola, M; Leibold, RA; Yealy, DM | 1 |
| Anderson, RF; Hoffman, LG; Ornitz, RD; Scarantino, CW | 1 |
| Aitken, ME; Carey, MJ | 1 |
| Bishop, JF; Matthews, JP; Olver, IN; Smith, RA | 1 |
| Fanning, J; Hilgers, RD | 1 |
| Burrell, LM; Hutchins, AM; Johnston, CI; Phillips, PA; Risvanis, J; Stephenson, J | 1 |
| Fleishman, SB; Lavin, MR; Sattler, M; Szarka, H | 1 |
| Fitzgerald, AL; Grigdesby, CF; Maickel, RP; Sprague, JE; Suckow, MA; Uetrecht, RL | 1 |
| Gin, T | 1 |
| Beveridge, R; Ducharme, J | 1 |
| Gilbert, CJ; Ohly, KV; Peters, WP; Rosner, G | 1 |
| Chun, E; Jones, J; Pack, S | 1 |
| Ali, PB; Graham, SG | 1 |
| Priestman, TJ | 1 |
| Dolman, J; Frighetto, L; Loewen, PS; Marra, CA | 1 |
| Chaudhary, A; Sharma, DR; Singh, S | 1 |
| Endo, K; Inoue, S; Suzuki, H | 1 |
| MacGregor, EA | 1 |
| JUSTIN-BESANCON, L; LAVILLE, C | 1 |
| Bsat, FA; Hoffman, DE; Seubert, DE | 1 |
| Andrews, J; Braude, D; Crandall, C; Hendey, G; Soliz, T; Weichenthal, L | 1 |
| Roberge, RJ | 1 |
| Celik, Y | 1 |
| Aghera, A; Bijur, P; Campbell, C; Chang, E; Dua, N; Esses, D; Friedman, BW; Gallagher, EJ; Greenwald, P; Hochberg, M; Lipton, RB; Paternoster, J; Radulescu, R; Solorzano, C; Valentin, T | 1 |
| Amini, R; Hays, DP; Patanwala, AE; Rosen, P | 1 |
| Trepanier, L | 1 |
| Jean, WH; Lin, TY; Lu, CW; Shieh, JS; Wu, CC | 1 |
| Egerton-Warburton, D; Mee, MJ; Meek, R | 1 |
| Wickham, R | 1 |
| Haas, DM; Lehmann, AS; McCormick, CL; Renbarger, JL; Rouse, C; Topletz, AR | 1 |
| Choi, H; Parmar, N | 1 |
| Barlow-Savko, E; Carlson, JN; Forehand, B | 1 |
| Kanis, JM; Timm, NL | 1 |
| Lax, JW; Saguil, A | 1 |
| Furyk, JS; McKenzie, S; Meek, R | 1 |
| Bachur, RG; Monuteaux, MC; Neuman, MI | 1 |
| Byczkowski, T; Chan, S; Kurowski, B; Timm, N | 1 |
| Gray, R; Lopes, V; Matteson, KA; Mayhall, EA | 1 |
| Gerard, JM; Kaar, CR; Nakanishi, AK | 1 |
| Egerton-Warburton, D; Furyk, JS; Meek, RA | 1 |
| Ando, Y; Gyawali, B; Hasegawa, Y; Honda, K; Maeda, O; Matsumoto, M; Sugishita, M; Tsukuura, H; Urakawa, H | 1 |
| Azariah, F; Bettiol, S; Lavender, VT; Smith, LA; Stoner, NS | 1 |
| Baggstrom, MQ; Chitneni, P; Gao, F; Govindan, R; Mann, J; Morgensztern, D; Waqar, MA; Waqar, SN; Williams, K | 1 |
| Fu, R; Hansen, ML; Laurie, A; Ma, OJ; Meckler, GD; Pacheco, S; Sheridan, DC | 1 |
| Garra, G; Singer, AJ; Thode, HC | 1 |
| Cleves, C; Kirkpatrick, L; Sogawa, Y | 1 |
| Ahmad, U; Burkins, J; Cirone, M; Desai, D; Jaber, S; Kandil, M; Lomotan, N; McDowell, M; Nuñez Cruz, S | 1 |
| Gray, M; Kane-Gill, S; Kellum, JA; Priyanka, P; Wang, L | 1 |
| Body, R; Chu, KH; Graham, CA; Horner, D; Kamona, S; Karamercan, MA; Keijzers, G; Kelly, AM; Kinnear, FB; Klim, S; Kuan, WS; Laribi, S; Roberts, T; Wijeratne, T | 1 |
| Brunette, ND; Chinn, E; Cole, JB; DeVries, P; Driver, BE; Klein, LR; Miner, JR; Mojica, E; Raiter, A; Stang, JL | 1 |
| Abd-ElGawad, M; Abdelhay, HM; Abdelmonem, H; Abdelwadoud, GT; Ahmed, AE; Al-Dardery, NM; Alhosini, ANM; Kamel, MA; Mohamed, SW | 1 |
13 review(s) available for metoclopramide and prochlorperazine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Recent advances in the management of chemotherapy-induced emesis].
Topics: Antiemetics; Antineoplastic Agents; Cisplatin; Dexamethasone; Domperidone; Dronabinol; Drug Therapy, Combination; Haloperidol; Humans; Metoclopramide; Nausea; Neoplasms; Prochlorperazine; Vomiting | 1986 |
Advances in anti-emetic therapy.
Topics: Antiemetics; Antineoplastic Agents; Chemoreceptor Cells; Clinical Trials as Topic; Dexamethasone; Domperidone; Dronabinol; Humans; Metoclopramide; Nausea; Prochlorperazine; Random Allocation; Receptors, Neurotransmitter; Vomiting | 1984 |
Anti-emetics.
Topics: Antiemetics; Domperidone; Dopamine Antagonists; Humans; Metoclopramide; Migraine Disorders; Nausea; Prochlorperazine; Vomiting | 2001 |
Antiemetic therapy for nausea and vomiting in the emergency department.
Topics: Antiemetics; Droperidol; Emergency Service, Hospital; Humans; Metoclopramide; Nausea; Ondansetron; Prochlorperazine; Promethazine; Vomiting | 2010 |
Acute vomiting in cats: rational treatment selection.
Topics: Acute Disease; Animals; Antiemetics; Cat Diseases; Cats; Chlorpromazine; Diarrhea; Famotidine; Indoles; Metoclopramide; Nausea; Ondansetron; Prochlorperazine; Quinolizines; Quinuclidines; Ranitidine; Sucralfate; Vomiting; Weight Loss | 2010 |
Evolving treatment paradigms for chemotherapy-induced nausea and vomiting.
Topics: Antiemetics; Antineoplastic Agents; Humans; Metoclopramide; Nausea; Prochlorperazine; Vomiting | 2012 |
BET 1: Metoclopramide or prochlorperazine for headache in acute migraine?
Topics: Acute Disease; Adult; Benchmarking; Emergency Service, Hospital; Evidence-Based Medicine; Humans; Metoclopramide; Migraine Disorders; Prochlorperazine; Randomized Controlled Trials as Topic; Treatment Outcome | 2013 |
The use of intravenous magnesium sulphate for acute migraine: meta-analysis of randomized controlled trials.
Topics: Acute Disease; Adult; Dopamine Antagonists; Double-Blind Method; Humans; Magnesium Sulfate; Metoclopramide; Migraine Disorders; Pain Measurement; Prochlorperazine; Randomized Controlled Trials as Topic; Treatment Failure | 2014 |
Acute migraine treatment in emergency settings.
Topics: Acute Disease; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antipsychotic Agents; Dexamethasone; Dopamine Antagonists; Droperidol; Emergency Service, Hospital; Glucocorticoids; Humans; Metoclopramide; Migraine Disorders; Practice Guidelines as Topic; Prochlorperazine | 2014 |
Drugs for the treatment of nausea and vomiting in adults in the emergency department setting.
Topics: Adult; Antiemetics; Droperidol; Emergency Service, Hospital; Female; Humans; Male; Metoclopramide; Nausea; Ondansetron; Prochlorperazine; Promethazine; Randomized Controlled Trials as Topic; Visual Analog Scale; Vomiting | 2015 |
Cannabinoids for nausea and vomiting in adults with cancer receiving chemotherapy.
Topics: Adult; Antiemetics; Antineoplastic Agents; Cannabinoids; Chlorpromazine; Dizziness; Domperidone; Euphoria; Humans; Metoclopramide; Nausea; Neoplasms; Prochlorperazine; Randomized Controlled Trials as Topic; Vomiting | 2015 |
The efficacy and safety of metoclopramide in relieving acute migraine attacks compared with other anti-migraine drugs: a systematic review and network meta-analysis of randomized controlled trials.
Topics: Chlorpromazine; Granisetron; Headache; Humans; Ketorolac; Metoclopramide; Migraine Disorders; Nausea; Network Meta-Analysis; Prochlorperazine; Randomized Controlled Trials as Topic; Sumatriptan; Valproic Acid | 2023 |
27 trial(s) available for metoclopramide and prochlorperazine
| Article | Year |
|---|---|
Amelioration of cancer chemotherapy-induced nausea and vomiting by delta-9-tetrahydrocannabinol.
Topics: Antiemetics; Antineoplastic Agents; Child; Clinical Trials as Topic; Double-Blind Method; Dronabinol; Humans; Metoclopramide; Nausea; Prochlorperazine; Vomiting | 1979 |
A randomised double-blind study of high-dose intravenous prochlorperazine versus high-dose metoclopramide as antiemetics for cancer chemotherapy.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents; Cisplatin; Female; Humans; Male; Metoclopramide; Middle Aged; Nausea; Prochlorperazine; Vomiting | 1992 |
A double-blind randomized cross-over comparison of high-dose prochlorperazine with high-dose metoclopramide for cisplatin-induced emesis.
Topics: Adult; Cisplatin; Dexamethasone; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Metoclopramide; Middle Aged; Neoplasms; Prochlorperazine; Vomiting | 1991 |
Prochlorperazine and transdermal scopolamine added to a metoclopramide antiemetic regimen. A controlled comparison.
Topics: Administration, Cutaneous; Cisplatin; Female; Genital Neoplasms, Female; Humans; Infusions, Intravenous; Metoclopramide; Middle Aged; Nausea; Prochlorperazine; Scopolamine; Surveys and Questionnaires; Vomiting | 1990 |
A randomized trial of oral nabilone and prochlorperazine compared to intravenous metoclopramide and dexamethasone in the treatment of nausea and vomiting induced by chemotherapy regimens containing cisplatin or cisplatin analogues.
Topics: Adolescent; Adult; Aged; Antiemetics; Cisplatin; Clinical Trials as Topic; Dexamethasone; Dronabinol; Drug Therapy, Combination; Female; Humans; Male; Metoclopramide; Middle Aged; Nausea; Neoplasms; Prochlorperazine; Random Allocation; Vomiting | 1988 |
The effect of metoclopramide and prochlorperazine on the absorption of effervescent paracetamol in migraine.
Topics: Acetaminophen; Administration, Rectal; Adult; Antiemetics; Female; Humans; Metoclopramide; Middle Aged; Migraine Disorders; Prochlorperazine | 1988 |
[A randomized controlled trial of acute and delayed cisplatin-induced emesis with metoclopramide, dexamethasone and prochlorperazine].
Topics: Adult; Aged; Cisplatin; Clinical Trials as Topic; Dexamethasone; Drug Therapy, Combination; Female; Humans; Lung Neoplasms; Male; Metoclopramide; Middle Aged; Nausea; Prochlorperazine; Random Allocation; Vomiting | 1987 |
Randomized, double-blind, cross-over study comparing prochlorperazine and lorazepam with high-dose metoclopramide and lorazepam for the control of emesis in patients receiving cytotoxic chemotherapy.
Topics: Adult; Aged; Antineoplastic Agents; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Lorazepam; Male; Metoclopramide; Middle Aged; Nausea; Prochlorperazine; Random Allocation; Vomiting | 1987 |
A comparison of the antiemetic efficacy of prochlorperazine and metoclopramide for the treatment of cisplatin-induced emesis: a prospective, randomized, double-blind study.
Topics: Adolescent; Adult; Aged; Cisplatin; Double-Blind Method; Drug Administration Schedule; Drug Evaluation; Female; Humans; Injections, Intravenous; Male; Metoclopramide; Middle Aged; Nausea; Prochlorperazine; Random Allocation; Time Factors | 1985 |
Advances in anti-emetic therapy.
Topics: Antiemetics; Antineoplastic Agents; Chemoreceptor Cells; Clinical Trials as Topic; Dexamethasone; Domperidone; Dronabinol; Humans; Metoclopramide; Nausea; Prochlorperazine; Random Allocation; Receptors, Neurotransmitter; Vomiting | 1984 |
Vomiting after anaesthesia for termination of pregnancy in Chinese.
Topics: Abortion, Induced; Anesthesia, Obstetrical; China; Ethnicity; Female; Humans; Metoclopramide; Preanesthetic Medication; Pregnancy; Prochlorperazine; Singapore; Vomiting | 1983 |
Antiemetic efficacy of high-dose metoclopramide: randomized trials with placebo and prochlorperazine in patients with chemotherapy-induced nausea and vomiting.
Topics: Adult; Aged; Cisplatin; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Metoclopramide; Middle Aged; Nausea; Neoplasms; Prochlorperazine; Random Allocation; Vomiting | 1981 |
Randomized, placebo-controlled evaluation of prochlorperazine versus metoclopramide for emergency department treatment of migraine headache.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Dopamine Antagonists; Double-Blind Method; Emergency Service, Hospital; Humans; Injections, Intravenous; Metoclopramide; Middle Aged; Migraine Disorders; Pain Measurement; Patient Satisfaction; Prochlorperazine; Prospective Studies; Treatment Outcome | 1995 |
On the mechanism of radiation-induced emesis: the role of serotonin.
Topics: Dexamethasone; Drug Therapy, Combination; Female; Hemibody Irradiation; Humans; Hydroxyindoleacetic Acid; Male; Metoclopramide; Ondansetron; Prochlorperazine; Radiation Injuries; Serotonin; Vomiting | 1994 |
The roles of patient and observer assessments in anti-emetic trials.
Topics: Cross-Over Studies; Double-Blind Method; Humans; Lorazepam; Metoclopramide; Nurses; Observer Variation; Patients; Prochlorperazine; Time Factors; Treatment Outcome; Vomiting | 1994 |
Ondansetron and metoclopramide fail to prevent vomiting secondary to ultra-high-dose cisplatin-carboplatin chemotherapy.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cisplatin; Dexamethasone; Diphenhydramine; Drug Therapy, Combination; Endometrial Neoplasms; Female; Humans; Lorazepam; Metoclopramide; Ondansetron; Ovarian Neoplasms; Prochlorperazine; Severity of Illness Index; Single-Blind Method; Treatment Failure; Vomiting | 1994 |
Effects of anti-emetics on water excretion in humans.
Topics: Adult; Atrial Natriuretic Factor; Body Water; Double-Blind Method; Humans; Injections, Intravenous; Male; Metoclopramide; Osmolar Concentration; Prochlorperazine; Sodium; Thirst; Urination; Water-Electrolyte Balance | 1994 |
Randomized, double-blind comparison of a prochlorperazine-based versus a metoclopramide-based antiemetic regimen in patients undergoing autologous bone marrow transplantation.
Topics: Adult; Antiemetics; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carmustine; Cisplatin; Clinical Protocols; Cyclophosphamide; Diphenhydramine; Double-Blind Method; Dronabinol; Female; Humans; Injections, Intravenous; Lorazepam; Male; Metoclopramide; Middle Aged; Nausea; Placebos; Prochlorperazine; Transplantation, Autologous; Vomiting | 1995 |
Intramuscular prochlorperazine versus metoclopramide as single-agent therapy for the treatment of acute migraine headache.
Topics: Acute Disease; Adult; Analgesics, Opioid; Antiemetics; Double-Blind Method; Emergency Service, Hospital; Female; Humans; Injections, Intramuscular; Male; Metoclopramide; Migraine Disorders; Pain Measurement; Prochlorperazine; Prospective Studies | 1996 |
Metoclopramide and prochlorperazine do not decrease propofol hypnotic requirements.
Topics: Adult; Anesthetics, Intravenous; Antiemetics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Female; Humans; Male; Metoclopramide; Prochlorperazine; Propofol | 1995 |
Evaluation of prochlorperazine buccal tablets (Bukatel) and metoclopramide oral tablets in the treatment of acute emesis.
Topics: Administration, Buccal; Administration, Oral; Adolescent; Adult; Aged; Antiemetics; Cholecystectomy; Female; Humans; Male; Metoclopramide; Middle Aged; Postoperative Nausea and Vomiting; Prochlorperazine; Quality of Life; Recurrence; Retreatment; Severity of Illness Index; Treatment Outcome | 1999 |
[Anti-emetic treatment for patients with lung cancer after chemotherapy, and usefulness of prochlorperazine for psychiatric emesis].
Topics: Aged; Antiemetics; Cisplatin; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Female; Granisetron; Humans; Lung Neoplasms; Male; Methylprednisolone; Metoclopramide; Middle Aged; Prochlorperazine; Vomiting, Anticipatory | 2000 |
Comparison of three outpatient regimens in the management of nausea and vomiting in pregnancy.
Topics: Adult; Antiemetics; Drug Therapy, Combination; Female; Humans; Hyperemesis Gravidarum; Metoclopramide; Nausea; Pregnancy; Pregnancy Complications; Prochlorperazine; Promethazine; Prospective Studies; Pyridoxine; Treatment Outcome; Vomiting | 2003 |
Antiemetics in the ED: a randomized controlled trial comparing 3 common agents.
Topics: Adult; Antiemetics; Droperidol; Emergency Service, Hospital; Female; Humans; Male; Metoclopramide; Middle Aged; Nausea; Prochlorperazine; Prospective Studies | 2006 |
A randomized controlled trial of prochlorperazine versus metoclopramide for treatment of acute migraine.
Topics: Adult; Diphenhydramine; Dopamine Antagonists; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Emergency Service, Hospital; Female; Humans; Injections, Intravenous; Male; Metoclopramide; Migraine Disorders; Patient Satisfaction; Prochlorperazine; Severity of Illness Index; Time Factors | 2008 |
Antiemetic efficacy of metoclopramide and diphenhydramine added to patient-controlled morphine analgesia: a randomised controlled trial.
Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Antiemetics; Dexamethasone; Diphenhydramine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hysterectomy; Metoclopramide; Middle Aged; Morphine; Pain, Postoperative; Postoperative Nausea and Vomiting; Prochlorperazine | 2010 |
MAGraine: Magnesium compared to conventional therapy for treatment of migraines.
Topics: Administration, Intravenous; Adult; Double-Blind Method; Female; Humans; Magnesium; Male; Metoclopramide; Middle Aged; Migraine Disorders; Patient Satisfaction; Prochlorperazine; Prospective Studies; Severity of Illness Index; Time Factors | 2021 |
52 other study(ies) available for metoclopramide and prochlorperazine
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
[Cytostatic treatment and nausea-suppressing agents].
Topics: Antiemetics; Antineoplastic Agents; Humans; Metoclopramide; Nausea; Neoplasms; Prochlorperazine | 1979 |
Pseudotetanus.
Topics: Adolescent; Adult; Child; Diagnosis, Differential; Drug Hypersensitivity; Female; Humans; Male; Meningitis, Viral; Metoclopramide; Middle Aged; Muscle Hypertonia; Prochlorperazine; Tetanus | 1979 |
[Action of chlorpromazine, prochlorperazine, metoclopramide and imipramine on central vagal stimulation of pancreatic secretion induced by 2-deoxy-D-glucose (author's transl)].
Topics: Animals; Chlorpromazine; Deoxy Sugars; Deoxyglucose; Imipramine; Metoclopramide; Pancreas; Prochlorperazine; Psychotropic Drugs; Rats; Stimulation, Chemical; Vagus Nerve | 1978 |
Extrapyramidal side effects of antiemetics presenting as psychiatric illness.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Akathisia, Drug-Induced; Antiemetics; Anxiety Disorders; Basal Ganglia Diseases; Drug Therapy, Combination; Female; Humans; Male; Metoclopramide; Neurologic Examination; Parkinson Disease, Secondary; Prochlorperazine; Psychomotor Agitation; Substance-Related Disorders | 1992 |
Acute and delayed emesis after cisplatin-based regimen: description and prevention.
Topics: Acute Disease; Antiemetics; Cisplatin; Dexamethasone; Dose-Response Relationship, Drug; Humans; Lorazepam; Metoclopramide; Nausea; Prochlorperazine; Time Factors; Vomiting | 1991 |
Adverse neuropsychiatric effects of dopamine antagonist medications. Misdiagnosis in the medical setting.
Topics: Adult; Brain; Diagnostic Errors; Dopamine Antagonists; Female; Humans; Male; Metoclopramide; Prochlorperazine; Receptors, Dopamine; Substance-Related Disorders | 1991 |
Persistent extrapyramidal syndrome with dystonia and rigidity caused by combined metoclopramide and prochlorperazine therapy.
Topics: Basal Ganglia Diseases; Cerebral Palsy; Dystonia; Female; Humans; Intellectual Disability; Metoclopramide; Middle Aged; Prochlorperazine; Syndrome | 1991 |
Extrapyramidal reactions to metoclopramide and prochlorperazine.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Akathisia, Drug-Induced; Basal Ganglia Diseases; Child; Dyskinesia, Drug-Induced; Dystonia; Humans; Metoclopramide; Middle Aged; Parkinson Disease, Secondary; Prochlorperazine; Prospective Studies | 1989 |
Metoclopramide and prochlorperazine: "the blue-tongue sign".
Topics: Adult; Drug Interactions; Female; Humans; Metoclopramide; Pigmentation Disorders; Prochlorperazine; Tongue Diseases | 1989 |
Acute upper airway obstruction due to supraglottic dystonia induced by a neuroleptic.
Topics: Adolescent; Adult; Airway Obstruction; Benztropine; Dystonia; Epiglottis; Humans; Male; Metoclopramide; Prochlorperazine; Radiography | 1988 |
Vomiting after ophthalmic surgery. Effects of intra-operative antiemetics and postoperative oral fluid restriction.
Topics: Adult; Antiemetics; Drinking; Droperidol; Female; Humans; Male; Metoclopramide; Middle Aged; Ophthalmologic Surgical Procedures; Postoperative Complications; Postoperative Period; Prochlorperazine; Prospective Studies; Vomiting | 1987 |
Prochlorperazine and vomiting after eye surgery.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Droperidol; Drug Therapy, Combination; Humans; Infant; Infant, Newborn; Metoclopramide; Middle Aged; Ophthalmologic Surgical Procedures; Postoperative Complications; Prochlorperazine; Vomiting | 1987 |
[Cisplatin drug therapy. Antiemetic treatment. Experiences with the use of high-dose metoclopramide combined with chlopromazine and prochlorperazine].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorpromazine; Cisplatin; Dose-Response Relationship, Drug; Drug Therapy, Combination; Etoposide; Female; Humans; Lung Neoplasms; Male; Metoclopramide; Middle Aged; Nausea; Prochlorperazine; Vomiting | 1985 |
High-dose intravenous metoclopramide and intermittent intramuscular prochlorperazine and diazepam in the management of emesis induced by cis-dichlorodiammineplatinum.
Topics: Antiemetics; Cisplatin; Diazepam; Drug Therapy, Combination; Humans; Injections, Intramuscular; Metoclopramide; Prochlorperazine; Vomiting | 1985 |
Letter: Metaclopramide and prolactin.
Topics: Breast Neoplasms; Humans; Metoclopramide; Prochlorperazine; Prolactin | 1974 |
Interaction of dopamine receptor ligands with subtypes of the opiate receptor.
Topics: Animals; Binding, Competitive; Brain; Bromocriptine; Dopamine Antagonists; Drug Interactions; Haloperidol; In Vitro Techniques; Ligands; Male; Membranes; Metoclopramide; Naloxone; Pimozide; Prochlorperazine; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Opioid; Tritium | 1984 |
[Vomiting accompanying cytostatic treatment, and its control].
Topics: Antiemetics; Antineoplastic Agents; Dronabinol; Drug Evaluation; Histamine H1 Antagonists; Humans; Metoclopramide; Neoplasms; Prochlorperazine; Vomiting | 1984 |
[Emesis due to cytostatic drugs. Update and review of our experiences].
Topics: Antineoplastic Agents; Dexamethasone; Haloperidol; Humans; Metoclopramide; Prochlorperazine; Vomiting | 1983 |
Acute dystonic reactions in childhood to drugs.
Topics: Antiemetics; Child; Child, Preschool; Dystonia; Female; Humans; Infant; Male; Metoclopramide; Prochlorperazine | 1980 |
Diverse effects of antiemetics in children.
Topics: Antiemetics; Basal Ganglia Diseases; Child; Child, Preschool; Drug Overdose; Female; Gastroenteritis; Humans; Infant; Male; Metoclopramide; Phenothiazines; Prochlorperazine | 1994 |
Antiemetic-induced akathisia in cancer patients receiving chemotherapy.
Topics: Akathisia, Drug-Induced; Antineoplastic Agents; Drug Therapy, Combination; Female; Humans; Male; Metoclopramide; Middle Aged; Nausea; Neoplasms; Prochlorperazine; Prospective Studies; Surveys and Questionnaires; Telephone; Vomiting | 1994 |
Pharmacological studies of centrifugation-induced analgesia.
Topics: Analgesia; Animals; Endorphins; Male; Metoclopramide; Naloxone; Pain Measurement; Parasympathetic Nervous System; Prochlorperazine; Rats; Rats, Sprague-Dawley; Reaction Time; Rotation; Vestibule, Labyrinth | 1993 |
Anaesthesia and breast feeding.
Topics: Anesthesia, Obstetrical; Anesthetics; Atropine; Breast Feeding; Female; Humans; Infant, Newborn; Metoclopramide; Milk, Human; Neostigmine; Prochlorperazine | 1993 |
Prochlorperazine or metoclopramide?
Topics: Antiemetics; Humans; Metoclopramide; Migraine Disorders; Prochlorperazine; Research Design | 1996 |
Controlling the toxicity of palliative radiotherapy: the role of 5-HT3 antagonists.
Topics: Antiemetics; Clinical Trials as Topic; Dopamine Antagonists; Humans; Metoclopramide; Nausea; Neoplasms; Ondansetron; Palliative Care; Prochlorperazine; Quality of Life; Radiotherapy; Serotonin Antagonists; Vomiting | 1996 |
Cost-effectiveness of prophylactic dolasetron or droperidol vs rescue therapy in the prevention of PONV in ambulatory gynecologic surgery.
Topics: Ambulatory Surgical Procedures; Antiemetics; Canada; Cost-Benefit Analysis; Decision Support Techniques; Decision Trees; Droperidol; Drug Costs; Female; Forecasting; Gynecologic Surgical Procedures; Humans; Indoles; Injections, Intravenous; Intraoperative Care; Metoclopramide; Postoperative Nausea and Vomiting; Probability; Prochlorperazine; Quinolizines; Sensitivity and Specificity; Treatment Outcome | 1999 |
[ANTIEMETIC ACTION OF METOCLOPRAMIDE WITH RESPECT TO APOMORPHINE AND HYDERGINE].
Topics: Antiemetics; Apomorphine; Benzamides; Cardiovascular Agents; Chlorpromazine; Dihydroergotoxine; Diphenhydramine; Dogs; Ergoloid Mesylates; Ergot Alkaloids; Metoclopramide; Oxytocics; Pharmacology; Prochlorperazine; Research; Toxicology | 1964 |
Antiemetic-related dystonic reaction unmasked by removal of a scopolamine transdermal patch.
Topics: Administration, Topical; Adult; Antiemetics; Dexamethasone; Dopamine Antagonists; Dystonia; Emergency Service, Hospital; Female; Humans; Metoclopramide; Muscarinic Antagonists; Ondansetron; Postoperative Nausea and Vomiting; Prochlorperazine; Scopolamine | 2006 |
Antiemetics in the ED: a randomized controlled trial comparing 3 common agents.
Topics: Antiemetics; Droperidol; Emergency Service, Hospital; Humans; Metoclopramide; Nausea; Prochlorperazine; Randomized Controlled Trials as Topic; Reference Values | 2006 |
Treatment and assessment of emergency department nausea and vomiting in Australasia: a survey of anti-emetic management.
Topics: Antiemetics; Australia; Clinical Protocols; Cross-Sectional Studies; Dopamine Antagonists; Emergency Service, Hospital; Health Care Surveys; Humans; Metoclopramide; Nausea; Prochlorperazine; Vomiting | 2011 |
Pharmacogenetic predictors of nausea and vomiting of pregnancy severity and response to antiemetic therapy: a pilot study.
Topics: Adult; Antiemetics; Female; Humans; Metoclopramide; Morning Sickness; Ondansetron; Pilot Projects; Polymorphism, Single Nucleotide; Pregnancy; Pregnancy Trimester, First; Pregnancy Trimester, Second; Prochlorperazine; Promethazine; Receptors, Serotonin, 5-HT3; Severity of Illness Index; Treatment Outcome; Young Adult | 2013 |
Antiemetic use in US EDs.
Topics: Adolescent; Adult; Aged; Antiemetics; Emergency Service, Hospital; Female; Humans; Male; Metoclopramide; Middle Aged; Ondansetron; Practice Patterns, Physicians'; Prochlorperazine; Promethazine; United States; Young Adult | 2014 |
Chlorpromazine for the treatment of migraine in a pediatric emergency department.
Topics: Adolescent; Child; Chlorpromazine; Cohort Studies; Dopamine Antagonists; Emergency Service, Hospital; Female; Humans; Male; Metoclopramide; Migraine Disorders; Pain Measurement; Pediatrics; Prochlorperazine; Retrospective Studies; Treatment Failure; Treatment Outcome; Young Adult | 2014 |
Drug treatment of adults with nausea and vomiting in primary care.
Topics: Adult; Antiemetics; Domperidone; Droperidol; Female; Histamine Antagonists; Humans; Male; Metoclopramide; Morning Sickness; Muscarinic Antagonists; Nausea; Ondansetron; Pregnancy; Primary Health Care; Prochlorperazine; Promethazine; Scopolamine; Vomiting | 2014 |
A comparison of acute treatment regimens for migraine in the emergency department.
Topics: Adolescent; Analgesics; Analgesics, Opioid; Child; Comparative Effectiveness Research; Diphenhydramine; Dopamine Antagonists; Drug Therapy, Combination; Emergency Service, Hospital; Female; Humans; Male; Metoclopramide; Migraine Disorders; Odds Ratio; Ondansetron; Patient Readmission; Prochlorperazine; Recurrence; Retrospective Studies; Risk Assessment; Tryptamines | 2015 |
Intravenous migraine therapy in children with posttraumatic headache in the ED.
Topics: Adolescent; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Brain Injuries; Child; Chlorpromazine; Cross-Sectional Studies; Emergency Service, Hospital; Female; Hospitals, Pediatric; Humans; Injections, Intravenous; Ketorolac; Male; Metoclopramide; Migraine Disorders; Ondansetron; Pain Measurement; Prochlorperazine; Retrospective Studies; Tomography, X-Ray Computed; Treatment Outcome; Young Adult | 2015 |
Comparison of antiemetics for nausea and vomiting of pregnancy in an emergency department setting.
Topics: Adult; Antiemetics; Cohort Studies; Emergency Service, Hospital; Female; Humans; Hypotension, Orthostatic; Ketosis; Length of Stay; Metoclopramide; Morning Sickness; Ondansetron; Pregnancy; Pregnancy Trimester, First; Prochlorperazine; Promethazine; Retrospective Studies; Treatment Outcome; Young Adult | 2015 |
The Use of a Pediatric Migraine Practice Guideline in an Emergency Department Setting.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Dihydroergotamine; Diphenhydramine; Emergency Service, Hospital; Female; Guideline Adherence; Humans; Hypnotics and Sedatives; Ketorolac; Length of Stay; Male; Metoclopramide; Migraine Disorders; Pain Management; Pain Measurement; Practice Guidelines as Topic; Prochlorperazine; Treatment Outcome; Vasoconstrictor Agents | 2016 |
Prophylactic Use of Antiemetics for Prevention of Opioid-Induced Nausea and Vomiting: A Questionnaire Survey among Japanese Physicians.
Topics: Analgesics, Opioid; Antiemetics; Benzodiazepines; Chemoprevention; Domperidone; Health Care Surveys; Humans; Japan; Metoclopramide; Nausea; Neoplasms; Olanzapine; Pain; Practice Patterns, Physicians'; Prochlorperazine; Steroids; Vomiting | 2015 |
Delayed nausea and vomiting from carboplatin doublet chemotherapy.
Topics: Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Female; Humans; Lorazepam; Male; Metoclopramide; Middle Aged; Nausea; Neoplasms; Prochlorperazine; Prospective Studies; Surveys and Questionnaires; Vomiting | 2016 |
Relative Effectiveness of Dopamine Antagonists for Pediatric Migraine in the Emergency Department.
Topics: Adolescent; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Child; Cohort Studies; Dopamine Antagonists; Drug Therapy, Combination; Emergency Service, Hospital; Female; Humans; Ketorolac; Male; Metoclopramide; Migraine Disorders; Pain Measurement; Prochlorperazine; Promethazine; Retrospective Studies; Treatment Failure; Treatment Outcome | 2018 |
Oligoantiemesis or Inadequate Prescription of Antiemetics in the Emergency Department: A Local and National Perspective.
Topics: Adult; Antiemetics; Emergency Service, Hospital; Female; Humans; Logistic Models; Male; Metoclopramide; Nausea; Ondansetron; Prochlorperazine; Promethazine; Retrospective Studies; Vomiting | 2016 |
Acute Dystonic Reactions in Children Treated for Headache With Prochlorperazine or Metoclopramide.
Topics: Adolescent; Child; Dopamine Antagonists; Drug-Related Side Effects and Adverse Reactions; Dystonia; Female; Headache Disorders, Primary; Hospitals, Pediatric; Humans; Male; Metoclopramide; Prochlorperazine; Retrospective Studies; Tertiary Care Centers | 2020 |
Kidney and Mortality Outcomes Associated with Ondansetron in Critically Ill Patients.
Topics: Acute Kidney Injury; Antiemetics; Critical Illness; Humans; Intensive Care Units; Kidney; Metoclopramide; Ondansetron; Prochlorperazine | 2022 |
Migraine in the Emergency Department: A Prospective Multinational Study of Patient Characteristics, Management, and Outcomes.
Topics: Adult; Emergency Service, Hospital; Female; Humans; Metoclopramide; Migraine Disorders; Prochlorperazine; Prospective Studies | 2022 |
Comparison of efficacy and frequency of akathisia and dystonia between olanzapine, metoclopramide and prochlorperazine in ED headache patients.
Topics: Cohort Studies; Double-Blind Method; Dystonia; Emergency Service, Hospital; Headache; Humans; Metoclopramide; Migraine Disorders; Olanzapine; Prochlorperazine; Psychomotor Agitation | 2023 |