metoclopramide and procainamide

metoclopramide has been researched along with procainamide in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19908 (26.67)18.7374
1990's4 (13.33)18.2507
2000's11 (36.67)29.6817
2010's7 (23.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Erhardt, PW; Hanna, RG; Lampe, JW; Lumma, WC; Sullivan, ME; Wong, SS1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Alagna, S; Delitala, G; Devilla, L; Masala, A1
Cheymol, G; Mouillé, P1
Bateman, DN1
Angrist, BM1
Fontaine, J; Reuse, J1
Brambilla, G; Campart, GB; Canonero, R; Martelli, A; Mattioli, F1
Allavena, A; Brambilla, G; Ghia, M; Martelli, A; Mereto, E; Robbiano, L1
Hua, J; Pero, RW1
Hua, J; Kane, R; Pero, RW1
Leanderson, T; Lindgren, H; Olsson, AR; Pero, RW1
CASTERA, R; CORNET, A; ECOIFFIER, J; GRIVAUX, M; GUERRE, J; JUSTIN-BESANCON, L; WATTEZ, E1
BOISSIER, JR; FICHELLE-PAGNY, J; LWOFF, JM; SIMON, P1

Reviews

2 review(s) available for metoclopramide and procainamide

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Pharmacokinetics and metabolism of the benzamides.
    Advances in biochemical psychopharmacology, 1982, Volume: 35

    Topics: Acecainide; Animals; Benzamides; Disease; Half-Life; Humans; Kinetics; Metoclopramide; Procainamide; Sulpiride

1982

Other Studies

28 other study(ies) available for metoclopramide and procainamide

ArticleYear
Heterocyclic analogues of benzamide antiarrhythmic agents.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:3

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Benzamides; Chemical Phenomena; Chemistry; Dogs; Electrophysiology; In Vitro Techniques; Papillary Muscles; Purkinje Fibers; Structure-Activity Relationship

1989
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Plasma prolactin response to L-dopa TRH and metaclopramide in thyrotoxicosis.
    Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1976, Volume: 25, Issue:5

    Topics: Female; Humans; Hyperthyroidism; Injections, Intravenous; Levodopa; Male; Metoclopramide; Procainamide; Prolactin

1976
[Cardiovascular and hemodynamic effects of derivatives of metoclopramide].
    Archives internationales de pharmacodynamie et de therapie, 1975, Volume: 215, Issue:1

    Topics: Animals; Blood Pressure; Cholinesterase Inhibitors; Dogs; Electrocardiography; Female; Heart Rate; Hemodynamics; Male; Metoclopramide; Myocardial Contraction; Procainamide; Respiration; Vascular Resistance

1975
The neurobiologically active benzamides and related compounds: some historical aspects.
    Advances in biochemical psychopharmacology, 1982, Volume: 35

    Topics: Benzamides; Chlorpromazine; Haloperidol; History, 20th Century; Humans; Metoclopramide; Nervous System; Procainamide; Sulpiride

1982
The effects of substituted benzamides on frog rectus abdominis.
    European journal of pharmacology, 1980, Nov-07, Volume: 68, Issue:1

    Topics: Amisulpride; Animals; Benzamides; Cholinesterase Inhibitors; In Vitro Techniques; Metoclopramide; Muscles; Procainamide; Rana esculenta; Sulpiride; Tiapamil Hydrochloride

1980
Testing of metoclopramide and procainamide for their ability to induce genotoxic effects in cultured mammalian cells.
    Toxicology and applied pharmacology, 1995, Volume: 131, Issue:2

    Topics: Animals; Autoradiography; Cells, Cultured; Cricetinae; Cricetulus; DNA Repair; DNA, Single-Stranded; Humans; Liver; Lung; Lymphocytes; Male; Metoclopramide; Micronuclei, Chromosome-Defective; Mutagenicity Tests; Mutagens; Procainamide; Rats; Rats, Sprague-Dawley

1995
Evaluation of DNA-damaging, clastogenic, and promoting activities of metoclopramide and procainamide in rats.
    Toxicology and applied pharmacology, 1995, Volume: 131, Issue:2

    Topics: Administration, Oral; Animals; Carcinogens; DNA; Liver; Male; Metoclopramide; Micronucleus Tests; Mutagens; Nitroso Compounds; Procainamide; Rats; Rats, Sprague-Dawley

1995
Toxicity, antitumor and chemosensitizing effects of 3-chloroprocainamide.
    Acta oncologica (Stockholm, Sweden), 1997, Volume: 36, Issue:8

    Topics: Animals; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Cisplatin; Dose-Response Relationship, Drug; Drug Interactions; Drug Screening Assays, Antitumor; Female; Humans; Male; Metoclopramide; Mice; Mice, SCID; Neoplasm Transplantation; Procainamide; Transplantation, Heterologous

1997
Pharmacokinetics and central nervous system toxicity of declopramide (3-chloroprocainamide) in rats and mice.
    Anti-cancer drugs, 1999, Volume: 10, Issue:1

    Topics: Administration, Oral; Animals; Antiemetics; Biological Availability; Central Nervous System; Dopamine Antagonists; Dose-Response Relationship, Drug; Female; Metoclopramide; Mice; Mice, SCID; Procainamide; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Sleep Stages; Tissue Distribution

1999
Mechanism of action for N-substituted benzamide-induced apoptosis.
    British journal of cancer, 2002, Mar-18, Volume: 86, Issue:6

    Topics: Apoptosis; Benzamides; Caspase 9; Caspases; Cytochrome c Group; Enzyme Activation; G2 Phase; HL-60 Cells; Humans; Metoclopramide; Mitosis; Procainamide; Proto-Oncogene Proteins c-bcl-2; Tumor Suppressor Protein p53

2002
[SENSORIMOTOR DISTURBANCES IN DUODENAL ULCER. RADIOLOGIC TEST AND COURSE UNDER METOCLOPRAMIDE].
    Archives des maladies de l'appareil digestif et des maladies de la nutrition, 1964, Volume: 53

    Topics: Antiemetics; Atropine; Drug Therapy; Duodenal Ulcer; Gastrointestinal Motility; Humans; Metoclopramide; Procainamide; Radiography

1964
[PSYCHOLEPTIC ACTION OF METOCLOPRAMIDE].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1964, Volume: 158

    Topics: Acetylcholine; Antiemetics; Apomorphine; Barbiturates; Behavior, Animal; Blood Pressure; Blood Pressure Determination; Dogs; Epinephrine; Humans; Male; Metoclopramide; Mice; Norepinephrine; Pharmacology; Procainamide; Psychopharmacology; Rats; Research; Seminal Vesicles; Toxicology

1964