metoclopramide has been researched along with prazosin in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (34.78) | 18.7374 |
| 1990's | 1 (4.35) | 18.2507 |
| 2000's | 7 (30.43) | 29.6817 |
| 2010's | 6 (26.09) | 24.3611 |
| 2020's | 1 (4.35) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Esaki, T; Kawashima, H; Komura, H; Kuroda, M; Mizuguchi, K; Natsume-Kitatani, Y; Ohashi, R; Watanabe, R | 1 |
| Andries, LJ; Brutsaert, DL; Meulemans, AL; Shah, AM | 1 |
| Kaufman, JM; Kesner, JS; Knobil, E; Wilson, RC | 1 |
| Bockaert, J; Lafon-Cazal, M | 1 |
| Hall, N; Liebman, JM; Prowse, J | 1 |
| Borsini, F; Nowakowska, E; Samanin, R | 1 |
| Costall, B; Gunning, SJ; Naylor, RJ; Simpson, KH | 1 |
| Fenton, HM; Liebman, JM | 1 |
| Alander, T; Andén, NE; Grabowska-Andén, M | 1 |
| Kinoshita, K; Seki, H; Takai, Y | 1 |
| Chen, BM; Li, HD; Liu, XL; Yan, M; Zhu, YG | 1 |
1 review(s) available for metoclopramide and prazosin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for metoclopramide and prazosin
| Article | Year |
|---|---|
Determination of metoclopramide in human plasma by LC-ESI-MS and its application to bioequivalance studies.
Topics: Administration, Oral; Asian People; Calibration; Chromatography, Liquid; Drug Stability; Humans; Linear Models; Male; Metoclopramide; Prazosin; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Therapeutic Equivalency | 2010 |
21 other study(ies) available for metoclopramide and prazosin
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Development of an
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Cell Line; Computer Simulation; Endothelial Cells; Gene Knockout Techniques; Humans; Organic Chemicals; Rats, Transgenic | 2021 |
Endocardium modulates myocardial inotropic response to 5-hydroxytryptamine.
Topics: Animals; Cats; Endocardium; Endothelium, Vascular; In Vitro Techniques; Ketanserin; Kinetics; Metoclopramide; Microscopy, Electron, Scanning; Myocardial Contraction; Papillary Muscles; Prazosin; Propranolol; Serotonin; Ventricular Function | 1989 |
Electrophysiological manifestation of luteinizing hormone-releasing hormone pulse generator activity in the rhesus monkey: influence of alpha-adrenergic and dopaminergic blocking agents.
Topics: Adrenergic alpha-Antagonists; Animals; Dopamine Antagonists; Electrophysiology; Female; Gonadotropin-Releasing Hormone; Macaca; Macaca mulatta; Metoclopramide; Phenoxybenzamine; Phentolamine; Prazosin; Yohimbine | 1985 |
Pharmacological characterization of octopamine-sensitive adenylate cyclase in the flight muscle of Locusta migratoria L.
Topics: Adenylyl Cyclases; Adrenergic alpha-Agonists; Animals; Catecholamines; Chlorphenamidine; Chlorpromazine; Flight, Animal; Grasshoppers; In Vitro Techniques; Male; Metoclopramide; Mianserin; Muscles; Octopamine; Phentolamine; Prazosin; Receptors, Adrenergic; Receptors, Biogenic Amine; Serotonin; Synephrine; Tyramine | 1985 |
Effects of various catecholamine receptor antagonists, muscle relaxation and physical hindrance on shuttlebox self-stimulation.
Topics: Adrenergic alpha-Antagonists; Animals; Brain; Clozapine; Haloperidol; Male; Methocarbamol; Metoclopramide; Muscle Relaxants, Central; Prazosin; Rats; Rats, Inbred F344; Reaction Time; Receptors, Dopamine; Self Stimulation | 1982 |
Effect of repeated treatment with desipramine in the behavioral "despair" test in rats: antagonism by "atypical" but not "classical" neuroleptics or antiadrenergic drugs.
Topics: Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Butyrophenones; Chlorpromazine; Clonidine; Clozapine; Depressive Disorder; Desipramine; Dibenzazepines; Haloperidol; Humans; Male; Metoclopramide; Phentolamine; Prazosin; Propranolol; Rats; Sulpiride | 1984 |
A central site of action for benzamide facilitation of gastric emptying.
Topics: Animals; Apomorphine; Atropine; Benzamides; Female; Gastric Emptying; Guinea Pigs; Male; Metoclopramide; Prazosin; Propranolol | 1983 |
Self-stimulation response decrement patterns differentiate clonidine, baclofen and dopamine antagonists from drugs causing performance deficit.
Topics: Animals; Baclofen; Clonidine; Conditioning, Operant; Dopamine Antagonists; Extinction, Psychological; Haloperidol; Male; Methocarbamol; Metoclopramide; Prazosin; Rats; Rats, Inbred F344; Receptors, Dopamine; Self Stimulation | 1982 |
Metoclopramide and sulpiride as selective blocking agents of pre- and postsynaptic dopamine receptors.
Topics: Aminooxyacetic Acid; Animals; Apomorphine; Atropine; Corpus Striatum; Dopamine; Dopamine Antagonists; Male; Metoclopramide; Norepinephrine; Prazosin; Rats; Receptors, Dopamine; Rotation; Sulpiride | 1980 |
Pheochromocytoma in pregnancy manifesting hypertensive crisis induced by metoclopramide.
Topics: Adrenal Gland Neoplasms; Adrenergic alpha-Antagonists; Adult; Antiemetics; Female; Humans; Hypertension; Magnetic Resonance Imaging; Metoclopramide; Pheochromocytoma; Prazosin; Pregnancy; Pregnancy Complications, Neoplastic | 1997 |