metoclopramide and perphenazine

metoclopramide has been researched along with perphenazine in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19902 (10.53)18.7374
1990's4 (21.05)18.2507
2000's8 (42.11)29.6817
2010's5 (26.32)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Ahman, M; Holmén, AG; Wan, H1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Aebelholt, A; Olesen, J; Veilis, B1
Bernton, E; Bryant, H; Dave, J; Holaday, J1
Kawashima, S; Mori, T; Park, MK; Sakamoto, S; Singtripop, T1
Costall, B; Naylor, RJ1
Clark, K; Cronin, MK; Darvish, AH; Desilva, PH; McDonald, SM1
Freiberger, D; Gosnell, JL; Steinbrook, RA1
Davidson, A; Hunter, C; Jankovic, J; Kenney, C1

Reviews

1 review(s) available for metoclopramide and perphenazine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for metoclopramide and perphenazine

ArticleYear
The efficacy of prophylactic ondansetron, droperidol, perphenazine, and metoclopramide in the prevention of nausea and vomiting after major gynecologic surgery.
    Anesthesia and analgesia, 1995, Volume: 81, Issue:1

    Topics: Akathisia, Drug-Induced; Consciousness; Double-Blind Method; Droperidol; Female; Humans; Hypotension; Hysterectomy; Injections, Intravenous; Metoclopramide; Middle Aged; Nausea; Ondansetron; Perphenazine; Placebos; Postoperative Complications; Prospective Studies; Vomiting

1995
Prophylactic antiemetics for laparoscopic cholecystectomy: a comparison of perphenazine, droperidol plus ondansetron, and droperidol plus metoclopramide.
    Journal of clinical anesthesia, 1998, Volume: 10, Issue:6

    Topics: Adult; Aged; Antiemetics; Cholecystectomy, Laparoscopic; Double-Blind Method; Droperidol; Female; Humans; Male; Metoclopramide; Middle Aged; Nausea; Ondansetron; Perphenazine; Postoperative Complications; Prospective Studies; Vomiting

1998

Other Studies

16 other study(ies) available for metoclopramide and perphenazine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
The Copenhagen Acute Headache Clinic: organization, patient material and treatment results.
    Headache, 1979, Volume: 19, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Aged; Analgesics; Anti-Anxiety Agents; Biperiden; Denmark; Female; Headache; Humans; Male; Metoclopramide; Middle Aged; Migraine Disorders; Outpatient Clinics, Hospital; Perphenazine; Promazine

1979
Prolactin and prolactin secretagogues reverse immunosuppression in mice treated with cysteamine, glucocorticoids, or cyclosporin-A.
    Brain, behavior, and immunity, 1992, Volume: 6, Issue:4

    Topics: Adrenocorticotropic Hormone; Animals; Bromocriptine; Corticosterone; Cyclosporine; Cysteamine; Glucocorticoids; Hemolytic Plaque Technique; Lymphocyte Activation; Male; Metoclopramide; Mice; Mice, Inbred C3H; Mice, Inbred DBA; Perphenazine; Pituitary-Adrenal System; Prolactin; Spleen

1992
Development of uterine adenomyosis after treatment with dopamine antagonists in mice.
    Life sciences, 1991, Volume: 49, Issue:3

    Topics: Animals; Corpus Luteum; Dopamine Antagonists; Endometriosis; Estrus; Female; Metoclopramide; Mice; Perphenazine; Prolactin; Sulpiride; Uterine Neoplasms

1991
Is there a relationship between the involvement of extrapyramidal and mesolimbic brain areas with the cataleptic action of neuroleptic agents and their clinical antipsychotic effect?
    Psychopharmacologia, 1973, Volume: 32, Issue:2

    Topics: Animals; Aporphines; Benzoates; Butyrophenones; Catalepsy; Dioxoles; Extrapyramidal Tracts; Humans; Hypothalamus; Male; Metoclopramide; Perphenazine; Piperidines; Rats; Spiro Compounds; Thioridazine; Tranquilizing Agents

1973
Metoclopramide, an increasingly recognized cause of tardive dyskinesia.
    Journal of clinical pharmacology, 2008, Volume: 48, Issue:3

    Topics: Adverse Drug Reaction Reporting Systems; Aged; Amitriptyline; Dyskinesia, Drug-Induced; Haloperidol; Humans; Metoclopramide; Middle Aged; Perphenazine; Retrospective Studies; Texas; Thioridazine; Time Factors

2008