metoclopramide and loperamide

metoclopramide has been researched along with loperamide in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19903 (25.00)18.7374
1990's3 (25.00)18.2507
2000's1 (8.33)29.6817
2010's4 (33.33)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Artursson, P; Mateus, A; Matsson, P1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Moncrieff, J; Sommers, DK; van Wyk, M1
Bryson, JC; Dukes, GE; Heizer, WD; Kirby, MG; Powell, JR2
Sommers, DK; Steyn, AG; Van Wyk, M1
Berthold, HK; Heine, WE; Klein, PD1
Barbhaiya, RH; Knupp, CA; Milbrath, RL1
Castagné, V; Goineau, S; Guillaume, P1
Anoshchenko, O; Storelli, F; Unadkat, JD1

Reviews

1 review(s) available for metoclopramide and loperamide

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

3 trial(s) available for metoclopramide and loperamide

ArticleYear
Effect of altering small bowel transit time on sustained release theophylline absorption.
    Journal of clinical pharmacology, 1989, Volume: 29, Issue:8

    Topics: Adult; Delayed-Action Preparations; Gastrointestinal Transit; Humans; Intestinal Absorption; Intestine, Small; Loperamide; Male; Metoclopramide; Theophylline

1989
A novel stable isotope breath test: 13C-labeled glycosyl ureides used as noninvasive markers of intestinal transit time.
    The American journal of gastroenterology, 1995, Volume: 90, Issue:1

    Topics: Adolescent; Adult; Breath Tests; Carbon Dioxide; Carbon Radioisotopes; Feasibility Studies; Female; Gastrointestinal Transit; Glycosylation; Humans; Loperamide; Male; Mass Spectrometry; Metoclopramide; Middle Aged; Urea

1995
Effect of metoclopramide and loperamide on the pharmacokinetics of didanosine in HIV seropositive asymptomatic male and female patients.
    European journal of clinical pharmacology, 1993, Volume: 45, Issue:5

    Topics: Administration, Oral; Didanosine; Female; HIV Seropositivity; Humans; Loperamide; Male; Metoclopramide

1993

Other Studies

8 other study(ies) available for metoclopramide and loperamide

ArticleYear
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
    Journal of medicinal chemistry, 2014, Apr-10, Volume: 57, Issue:7

    Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2014
Influence of cisapride, metoclopramide and loperamide on gastric emptying of normal volunteers as measured by means of the area under the curve of the cumulative fraction absorbed-time profiles of paracetamol.
    Methods and findings in experimental and clinical pharmacology, 1992, Volume: 14, Issue:5

    Topics: Acetaminophen; Adult; Biological Availability; Cisapride; Gastric Emptying; Humans; Loperamide; Male; Metoclopramide; Piperidines; Serotonin Antagonists

1992
Effect of metoclopramide, bethanechol, and loperamide on gastric residence time, gastric emptying, and mouth-to-cecum transit time.
    Pharmacotherapy, 1989, Volume: 9, Issue:4

    Topics: Adolescent; Adult; Bethanechol Compounds; Gastric Emptying; Gastrointestinal Motility; Gastrointestinal Transit; Humans; Loperamide; Male; Metoclopramide; Piperidines

1989
Evaluation of gastrointestinal motility using the hydrogen breath test.
    British journal of clinical pharmacology, 1985, Volume: 20, Issue:5

    Topics: Adult; Breath Tests; Cisapride; Diphenoxylate; Female; Gastric Emptying; Gastrointestinal Motility; Humans; Hydrogen; Lactulose; Loperamide; Male; Metoclopramide; Piperidines; Random Allocation

1985
Comparison of the effects of clonidine, loperamide and metoclopramide in two models of gastric emptying in the rat.
    Fundamental & clinical pharmacology, 2015, Volume: 29, Issue:1

    Topics: Acetaminophen; Animals; Clonidine; Gastric Emptying; Gastric Mucosa; Intestine, Small; Loperamide; Male; Metoclopramide; Phenolsulfonphthalein; Rats; Rats, Wistar

2015
Successful Prediction of Human Steady-State Unbound Brain-to-Plasma Concentration Ratio of P-gp Substrates Using the Proteomics-Informed Relative Expression Factor Approach.
    Clinical pharmacology and therapeutics, 2021, Volume: 110, Issue:2

    Topics: Algorithms; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain; Brain Chemistry; Dogs; Endothelial Cells; Extracellular Fluid; Forecasting; Gene Expression Regulation; Humans; Loperamide; Madin Darby Canine Kidney Cells; Metoclopramide; Positron-Emission Tomography; Proteomics; Verapamil

2021