metoclopramide and lidocaine

metoclopramide has been researched along with lidocaine in 40 studies

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19902 (5.00)18.7374
1990's6 (15.00)18.2507
2000's19 (47.50)29.6817
2010's13 (32.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Ahman, M; Holmén, AG; Wan, H1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Chang, G; Di, L; Huang, Y; Lin, Z; Liston, TE; Scott, DO; Troutman, MD; Umland, JP1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Artursson, P; Mateus, A; Matsson, P1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Thomas, J1
Fee, JP; Ganta, R1
Roberts, RH; Sinclair, SW; Tan, ST1
Burke, M1
Prabhu, NV; Van den Berg, AA1
Mecklem, DW1
Kafle, SK1
Chang, DP; Hwang, MH; Liaw, WJ; Pang, WW1
Nieto, JE; Rakestraw, PC; Snyder, JR; Vatistas, NJ1
Fujii, Y; Numazaki, M1
Hassannasab, B; Khan, ZH; Majedi, H; Rabiee, M1
Ayuso, MA; Fernández, J; Gomar, C; Luis, M; Sala, X1
Fujii, Y; Nakayama, M2
Cripps, PJ; Dallap, BL; Edwards, GB; Proudman, CJ; Smith, MA1
Fujii, Y; Itakura, M1
Inokuma, H; Okamura, K; Sasaki, N; Yamada, H; Yamada, M1
Chaudhary, K; Gogia, AR; Gupta, P1
Aktay, M; Ozlü, O; Polat, R1
Buyuktimkin, T; Wurster, DE1
Bafuma, PJ; Nandi, A; Weisberg, M1
Akalın, LE; Alyeşil, C; Avcu, N; Doğan, NÖ; Pekdemir, M; Yaka, E; Yılmaz, S1

Reviews

2 review(s) available for metoclopramide and lidocaine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Incidence of pain upon injection of a new formula of propofol in a fat emulsion of medium- and long-chain triglycerides].
    Revista espanola de anestesiologia y reanimacion, 2004, Volume: 51, Issue:9

    Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Emulsions; Female; Humans; Incidence; Lidocaine; Male; Metoclopramide; Midazolam; Middle Aged; Molecular Weight; Pain; Premedication; Propofol; Prospective Studies; Triglycerides

2004

Trials

15 trial(s) available for metoclopramide and lidocaine

ArticleYear
Pain on injection of propofol: comparison of lignocaine with metoclopramide.
    British journal of anaesthesia, 1992, Volume: 69, Issue:3

    Topics: Adolescent; Adult; Aged; Double-Blind Method; Female; Humans; Injections, Intravenous; Lidocaine; Male; Metoclopramide; Middle Aged; Pain; Preanesthetic Medication; Propofol; Thrombophlebitis

1992
Lignocaine vs bupivacaine in prominent ear correction: a controlled trial.
    British journal of plastic surgery, 1992, Volume: 45, Issue:7

    Topics: Acetaminophen; Adolescent; Adult; Anesthesia, General; Anesthesia, Local; Bupivacaine; Child; Child, Preschool; Double-Blind Method; Ear, External; Female; Humans; Lidocaine; Male; Metoclopramide; Morphine; Pain, Postoperative; Vomiting

1992
Rationalizing venepuncture pain: comparison of lignocaine injection, Butterfly (21 gauge and 23 gauge) and Venflon (20 gauge).
    Anaesthesia and intensive care, 1995, Volume: 23, Issue:2

    Topics: Adolescent; Adult; Bloodletting; Catheterization, Peripheral; Diazepam; Equipment Design; Female; Humans; Injections, Subcutaneous; Lidocaine; Male; Metoclopramide; Middle Aged; Needles; Pain; Pain Measurement; Preanesthetic Medication; Sex Factors

1995
Propofol injection pain: comparing the addition of lignocaine or metoclopramide.
    Anaesthesia and intensive care, 1994, Volume: 22, Issue:5

    Topics: Adult; Anesthesia Recovery Period; Anesthesia, Intravenous; Blood Pressure; Extrapyramidal Tracts; Female; Heart Rate; Humans; Incidence; Injections, Intravenous; Lidocaine; Male; Metoclopramide; Nausea; Pain; Propofol; Prospective Studies; Pulse; Single-Blind Method; Vomiting

1994
Intrathecal meperidine for elective caesarean section: a comparison with lidocaine.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1993, Volume: 40, Issue:8

    Topics: Adult; Analgesia, Obstetrical; Anesthesia, Epidural; Apgar Score; Cesarean Section; Female; Humans; Hypotension; Infant, Newborn; Injections, Spinal; Intraoperative Complications; Lidocaine; Meperidine; Metoclopramide; Muscles; Pregnancy; Pruritus; Sensation; Sleep Stages; Time Factors

1993
Pain on injection of propofol: the mitigating influence of metoclopramide using different techniques.
    Acta anaesthesiologica Scandinavica, 1999, Volume: 43, Issue:1

    Topics: Adult; Analgesics; Analysis of Variance; Anesthetics, Intravenous; Anesthetics, Local; Chi-Square Distribution; Dopamine Antagonists; Double-Blind Method; Drug Combinations; Female; Humans; Incidence; Injections, Intravenous; Lidocaine; Male; Metoclopramide; Pain; Pain Measurement; Placebos; Propofol; Sodium Chloride; Time Factors; Tourniquets

1999
Subhypnotic dose of propofol for the prevention of nausea and vomiting during spinal anaesthesia for caesarean section.
    Anaesthesia and intensive care, 2000, Volume: 28, Issue:3

    Topics: Adult; Analysis of Variance; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Intravenous; Anesthetics, Local; Antiemetics; Cesarean Section; Double-Blind Method; Female; Humans; Incidence; Injections, Intravenous; Intraoperative Care; Lidocaine; Metoclopramide; Placebos; Postoperative Nausea and Vomiting; Pregnancy; Propofol; Safety

2000
A comparison of metoclopramide and lidocaine for preventing pain on injection of diazepam.
    Anesthesia and analgesia, 2002, Volume: 95, Issue:5

    Topics: Adjuvants, Anesthesia; Adult; Aged; Anesthetics, Local; Diazepam; Double-Blind Method; Female; Humans; Injections, Intravenous; Lidocaine; Male; Metoclopramide; Middle Aged; Pain; Prospective Studies

2002
[Incidence of pain upon injection of a new formula of propofol in a fat emulsion of medium- and long-chain triglycerides].
    Revista espanola de anestesiologia y reanimacion, 2004, Volume: 51, Issue:9

    Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Emulsions; Female; Humans; Incidence; Lidocaine; Male; Metoclopramide; Midazolam; Middle Aged; Molecular Weight; Pain; Premedication; Propofol; Prospective Studies; Triglycerides

2004
A lidocaine/metoclopramide combination decreases pain on injection of propofol.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2005, Volume: 52, Issue:5

    Topics: Adult; Anesthetics, Intravenous; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Lidocaine; Male; Metoclopramide; Middle Aged; Pain; Propofol

2005
Prevention of pain due to injection of propofol with IV administration of lidocaine 40 mg + metoclopramide 2.5, 5, or 10 mg or saline: a randomized, double-blind study in Japanese adult surgical patients.
    Clinical therapeutics, 2007, Volume: 29, Issue:5

    Topics: Adult; Aged; Anesthetics, Intravenous; Anesthetics, Local; Antiemetics; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Injections, Intravenous; Japan; Lidocaine; Male; Metoclopramide; Middle Aged; Pain; Propofol

2007
Comparison of lidocaine, metoclopramide, and flurbiprofen axetil for reducing pain on injection of propofol in Japanese adult surgical patients: a prospective, randomized, double-blind, parallel-group, placebo-controlled study.
    Clinical therapeutics, 2008, Volume: 30, Issue:2

    Topics: Adult; Aged; Analgesics; Anesthetics, Intravenous; Anesthetics, Local; Double-Blind Method; Female; Flurbiprofen; Humans; Injections, Intravenous; Japan; Lidocaine; Male; Metoclopramide; Middle Aged; Pain; Pain Measurement; Propofol; Prospective Studies; Surgical Procedures, Operative; Treatment Outcome; Young Adult

2008
A prospective, randomized, double-blind study to compare the efficacy of lidocaine + metoclopramide and lidocaine + ketamine combinations in preventing pain on propofol injection.
    Journal of anesthesia, 2013, Volume: 27, Issue:3

    Topics: Adult; Anesthetics, Combined; Anesthetics, Dissociative; Anesthetics, Intravenous; Anesthetics, Local; Antiemetics; Double-Blind Method; Female; Humans; Ketamine; Lidocaine; Male; Metoclopramide; Pain; Pain Measurement; Propofol; Prospective Studies

2013
The effects of remifentanil, lidocaine, metoclopramide, or ketamine pretreatment on propofol injection pain.
    Middle East journal of anaesthesiology, 2012, Volume: 21, Issue:5

    Topics: Adult; Aged; Analgesics; Double-Blind Method; Female; Humans; Injections, Intravenous; Ketamine; Lidocaine; Male; Metoclopramide; Middle Aged; Pain; Piperidines; Propofol; Prospective Studies; Remifentanil

2012
Intranasal Lidocaine in Acute Treatment of Migraine: A Randomized Controlled Trial.
    Annals of emergency medicine, 2017, Volume: 69, Issue:6

    Topics: Acute Disease; Administration, Intranasal; Adult; Anesthetics, Local; Antiemetics; Double-Blind Method; Emergency Medical Services; Female; Humans; Lidocaine; Male; Metoclopramide; Migraine Disorders; Pain Measurement; Prospective Studies; Severity of Illness Index; Time Factors; Treatment Outcome

2017

Other Studies

24 other study(ies) available for metoclopramide and lidocaine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Species independence in brain tissue binding using brain homogenates.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7

    Topics: Animals; Brain; Dogs; Guinea Pigs; Humans; Macaca fascicularis; Mice; Rats; Species Specificity

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
    Journal of medicinal chemistry, 2014, Apr-10, Volume: 57, Issue:7

    Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2014
Bioavailability of drugs administered intramuscularly.
    Australian family physician, 1977, Volume: 6, Issue:8

    Topics: Absorption; Administration, Oral; Biological Availability; Biopharmaceutics; Chlordiazepoxide; Diazepam; Diffusion; Female; Humans; Injections, Intramuscular; Injections, Intravenous; Lidocaine; Male; Metoclopramide; Phenytoin; Preanesthetic Medication

1977
Intravenous lignocaine for migraine headache.
    Australian family physician, 1989, Volume: 18, Issue:12

    Topics: Aspirin; Humans; Injections, Intravenous; Lidocaine; Metoclopramide; Migraine Disorders

1989
In vitro effects of erythromycin, lidocaine, and metoclopramide on smooth muscle from the pyloric antrum, proximal portion of the duodenum, and middle portion of the jejunum of horses.
    American journal of veterinary research, 2000, Volume: 61, Issue:4

    Topics: Animals; Anti-Arrhythmia Agents; Dopamine Antagonists; Duodenum; Erythromycin; Gastrointestinal Agents; Horse Diseases; Horses; In Vitro Techniques; Intestinal Obstruction; Jejunum; Lidocaine; Metoclopramide; Muscle Contraction; Muscle, Smooth; Postoperative Complications; Pyloric Antrum

2000
Evaluation of the clinical efficacy of prokinetic drugs in the management of post-operative ileus: can retrospective data help us?
    Veterinary journal (London, England : 1997), 2005, Volume: 170, Issue:2

    Topics: Animals; Cisapride; Digestive System Surgical Procedures; Erythromycin; Gastrointestinal Agents; Horse Diseases; Horses; Ileus; Lidocaine; Metoclopramide; Retrospective Studies; Risk Factors

2005
Effects of mosapride citrate, metoclopramide hydrochloride, lidocaine hydrochloride, and cisapride citrate on equine gastric emptying, small intestinal and caecal motility.
    Research in veterinary science, 2009, Volume: 86, Issue:2

    Topics: Animals; Benzamides; Breath Tests; Carbon Isotopes; Cisapride; Female; Gastric Emptying; Gastrointestinal Agents; Horses; Lidocaine; Male; Metoclopramide; Morpholines

2009
Quantitative Structure-Activity Relationship Analysis of the Effect of Metoclopramide and Related Compounds on the Surface Ionization of Fumed Silica.
    Journal of pharmaceutical sciences, 2015, Volume: 104, Issue:8

    Topics: Adsorption; Antiemetics; Benzamides; Dopamine D2 Receptor Antagonists; Drug Compounding; Excipients; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Kinetics; Lidocaine; Metoclopramide; Molecular Structure; Quantitative Structure-Activity Relationship; Silanes; Silicon Dioxide; Solubility; Surface Properties; Suspensions; Titrimetry; Voltage-Gated Sodium Channel Blockers

2015
Opiate refractory pain from an intestinal obstruction responsive to an intravenous lidocaine infusion.
    The American journal of emergency medicine, 2015, Volume: 33, Issue:10

    Topics: Abdominal Pain; Analgesics, Opioid; Anesthetics, Local; Antiemetics; Colostomy; Diagnosis, Differential; Emergency Service, Hospital; Female; Humans; Hydromorphone; Infusions, Intravenous; Intestinal Obstruction; Lidocaine; Metoclopramide; Oxycodone; Tomography, X-Ray Computed; Young Adult

2015