metoclopramide and caffeine

metoclopramide has been researched along with caffeine in 33 studies

Research

Studies (33)

Timeframe	Studies, this research(%)	All Research%
pre-1990	6 (18.18)	18.7374
1990's	5 (15.15)	18.2507
2000's	12 (36.36)	29.6817
2010's	8 (24.24)	24.3611
2020's	2 (6.06)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	2
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Ahman, M; Holmén, AG; Wan, H	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Peitersen, E; Vesterhauge, S	1
Saadah, HA	1
Manno, BR; Manno, JE; Mims, ME; Stewart, JJ; Wood, CD; Wood, MJ	1
Wilkinson, M	1
Kangasniemi, P; Neuvonen, PJ; Tokola, O; Tokola, RA	1
Boston, PF	1
Cunningham, B; Dougall, JR; Nimmo, WS	1
Gothoni, G; Hakkarainen, H; Parantainen, J; Vapaatalo, H	1
Anaya Ordóñez, S; Matas Hoces, A	1
Lessem, P; Wenokur, B	1
Geraud, G; Gómez, JP; Henry, P; Joffroy, A; Lainez, JM; Le Jeunne, C; Liaño, H; Pradalier, A; Titus i Albareda, F	1
Kozubski, W; Stepień, A	1
Chen, Y; Detre, JA; Fernández-Seara, MA; Wang, DJ	1
Alshehri, MM; Alzoman, NZ; Elshahed, MS; Maher, HM; Olah, IV; Rizk, MS; Sultan, MA	1
Abdelhamid, NS; Anwar, BH; Farid, NF; Magdy, MA; Naguib, IA	1
Abu Bakar, MA; Baharuddin, KA; Norhayati, MN; Nurathirah, MN; Yazid, MB	1

Reviews

2 review(s) available for metoclopramide and caffeine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Efficacy of ketorolac in the treatment of acute migraine attack: A systematic review and meta-analysis. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2022, Volume: 29, Issue:9 Topics: Caffeine; Dexamethasone; Diclofenac; Humans; Ketorolac; Metoclopramide; Migraine Disorders; Pain; Phenothiazines; Sumatriptan; Valproic Acid	2022

Trials

7 trial(s) available for metoclopramide and caffeine

Article	Year
Therapeutic effects of antimotion sickness medications on the secondary symptoms of motion sickness. Aviation, space, and environmental medicine, 1990, Volume: 61, Issue:2 Topics: Adolescent; Adult; Arousal; Caffeine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electroencephalography; Female; Gastric Emptying; Glucagon; Humans; Male; Metoclopramide; Motion Sickness; Randomized Controlled Trials as Topic; Scopolamine; Signal Processing, Computer-Assisted; Space Flight; Syndrome	1990
Tolfenamic acid, metoclopramide, caffeine and their combinations in the treatment of migraine attacks. Cephalalgia : an international journal of headache, 1984, Volume: 4, Issue:4 Topics: Adult; Analgesics; Caffeine; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Metoclopramide; Middle Aged; Migraine Disorders; ortho-Aminobenzoates	1984
Paracetamol absorption from Paramax, Panadol and Solpadeine. British journal of clinical pharmacology, 1983, Volume: 15, Issue:4 Topics: Acetaminophen; Administration, Oral; Adult; Caffeine; Codeine; Drug Combinations; Humans; Male; Metoclopramide	1983
Tolfenamic acid and caffeine: a useful combination in migraine. Cephalalgia : an international journal of headache, 1982, Volume: 2, Issue:4 Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Drug Combinations; Female; Humans; Metoclopramide; Middle Aged; Migraine Disorders; ortho-Aminobenzoates; Prostaglandin Antagonists; Pyridoxine; Random Allocation	1982
[Sumatriptan in the treatment of acute migraine: its role in primary health care]. Atencion primaria, 1994, Apr-30, Volume: 13, Issue:7 Topics: Acute Disease; Administration, Oral; Algorithms; Aspirin; Caffeine; Double-Blind Method; Drug Therapy, Combination; Ergotamine; Humans; Injections, Subcutaneous; Metoclopramide; Migraine Disorders; Recurrence; Sumatriptan	1994
Comparative efficacy and safety of calcium carbasalate plus metoclopramide versus ergotamine tartrate plus caffeine in the treatment of acute migraine attacks. European neurology, 1999, Volume: 41, Issue:1 Topics: Abdominal Pain; Adolescent; Adult; Aged; Analgesics; Aspirin; Caffeine; Double-Blind Method; Drug Therapy, Combination; Ergotamine; Female; Humans; Male; Metoclopramide; Middle Aged; Migraine Disorders; Nausea; Patient Acceptance of Health Care; Safety; Sleep Stages; Treatment Outcome; Urea	1999
[Comparison of the effectiveness of lysine acetylsalicylate and metoclopramide combination with ergotamine plus caffeine in the treatment of migraine attacks]. Wiadomosci lekarskie (Warsaw, Poland : 1960), 2004, Volume: 57, Issue:3-4 Topics: Adult; Aged; Analgesics, Non-Narcotic; Aspirin; Caffeine; Central Nervous System Stimulants; Dopamine Antagonists; Drug Therapy, Combination; Ergotamine; Female; Humans; Lysine; Male; Metoclopramide; Middle Aged; Migraine Disorders; Poland; Time Factors; Treatment Outcome	2004

Other Studies

24 other study(ies) available for metoclopramide and caffeine

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds. Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water	2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data. Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13 Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding	2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs. Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6 Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry	2009
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2 Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution	2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
The effects of some drugs on the caloric induced nystagmus. Advances in oto-rhino-laryngology, 1979, Volume: 25 Topics: Amphetamine; Atropine; Caffeine; Caloric Tests; Cyclizine; Eye Movements; Humans; Metoclopramide; Promethazine; Scopolamine; Thiethylperazine; Vestibule, Labyrinth	1979
Abortive migraine therapy with oral naproxen sodium plus metoclopramide plus ergotamine tartrate with caffeine. Headache, 1992, Volume: 32, Issue:2 Topics: Adult; Caffeine; Drug Combinations; Ergotamine; Humans; Metoclopramide; Middle Aged; Migraine Disorders; Naproxen; Retrospective Studies	1992
Migraine--treatment of acute attack. Scottish medical journal, 1985, Volume: 30, Issue:4 Topics: Acetaminophen; Acute Disease; Aspirin; Caffeine; Ergotamine; Ergotamines; Humans; Metoclopramide; Migraine Disorders; Sleep; Time Factors	1985
Paracetamol absorption from Paramax, Panadol and Solpadeine. British journal of clinical pharmacology, 1983, Volume: 16, Issue:5 Topics: Absorption; Acetaminophen; Caffeine; Codeine; Drug Combinations; Humans; Metoclopramide	1983
Caffeine withdrawal, metoclopramide, and depression. The American journal of gastroenterology, 1993, Volume: 88, Issue:9 Topics: Adult; Caffeine; Depressive Disorder; Drug Interactions; Humans; Male; Metoclopramide; Substance Withdrawal Syndrome	1993
Potentials and challenges for arterial spin labeling in pharmacological magnetic resonance imaging. The Journal of pharmacology and experimental therapeutics, 2011, Volume: 337, Issue:2 Topics: Antiemetics; Arteries; Caffeine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Humans; Hypnotics and Sedatives; Magnetic Resonance Imaging; Metoclopramide; Oxygen; Perfusion; Piperidines; Remifentanil; Spin Labels	2011
Capillary electrophoretic determination of antimigraine formulations containing caffeine, ergotamine, paracetamol and domperidone or metoclopramide. Journal of chromatographic science, 2013, Volume: 51, Issue:6 Topics: Acetaminophen; Caffeine; Domperidone; Drug Combinations; Drug Stability; Electrophoresis, Capillary; Ergotamine; Hydrogen-Ion Concentration; Limit of Detection; Linear Models; Metoclopramide; Migraine Disorders; Osmolar Concentration; Reproducibility of Results; Tablets; Tartrates; Temperature	2013
Validated ecofriendly chromatographic method for quantitative determination of anti-migraine quaternary mixture. Journal of separation science, 2020, Volume: 43, Issue:12 Topics: Acetaminophen; Caffeine; Chromatography, Thin Layer; Drug Compounding; Ergotamine; Metoclopramide; Molecular Structure	2020