Page last updated: 2024-08-23

metipranolol and timolol

metipranolol has been researched along with timolol in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199020 (57.14)18.7374
1990's8 (22.86)18.2507
2000's6 (17.14)29.6817
2010's1 (2.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bard, B; Carrupt, PA; Martel, S1
Bellman, K; Knegtel, RM; Settimo, L1
Bleckmann, H; Kessler, C; Kleintges, G1
Bacon, PJ; Brazier, DJ; Smith, R; Smith, SE1
Bringer, L; Dufier, JL; Hugues, FC; Le Jeunne, CL; Munera, Y1
James, IM1
De Heer, LJ; De Keizer, RJ; Maas, S; Ros, FE1
Brozek, B; Krejcí, L; Zobanová, A1
Boguszaková, J; Dientsbier, E; Dubská, Z; Hendl, J1
Mills, KB; Wright, G1
Strempel, I3
Bleckmann, H; Dorow, P1
Berlin, I; Le Hoang, P; Marcel, P; Millon, D; Puech, AJ; Uzzan, B1
Demailly, P; Ecoffet, M1
Böhm, E; Fabel, H1
Schnarr, KD1
Hugues, FC; Le Jeunne, C; Munera, Y; Teillet, L1
Draeger, J; Schneider, B; Winter, R1
Merté, HJ; Mertz, M; Stryz, JR1
Kruse, W1
Brettschneider, I; Brozek, B; Krejcí, L1
Hendrickson, JR; Weiss, MA1
Zimmerman, TJ1
Frishman, WH; Fuksbrumer, MS; Tannenbaum, M1
Hodes, BL; Watanabe, TM1
Drago, F; Emmi, I; Marino, V1
Bellone, A; Boles Carenini, B; Brogliatti, B; Dorigo, MT; Protti, R; Vadalà, G1
Bruynzeel, DP; Conemans, JM; de Groot, AC; Smeenk, G; van Ginkel, CJ1
Karaküçük, S; Mirza, GE; Temel, E1
Kijlstra, A; Mulder, M; van Beek, LM; van Haeringen, NJ1
Allmeier, H; Chidlow, G; Melena, J; Osborne, NN; Schmidt, KG; Wood, JP1
Allmeier, H; Djanani, A; Dunzendorfer, S; Kaneider, NC; Meierhofer, C; Sturn, D; Wiedermann, CJ1

Reviews

3 review(s) available for metipranolol and timolol

ArticleYear
Pharmacologic effects of beta-blocking agents used in the management of glaucoma.
    Survey of ophthalmology, 1989, Volume: 33 Suppl

    Topics: Adrenergic beta-Antagonists; Betaxolol; Carteolol; Glaucoma; Heart Rate; Humans; Intraocular Pressure; Levobunolol; Metipranolol; Propanolamines; Solubility; Timolol

1989
Topical ophthalmic beta blockers: a comparative review.
    Journal of ocular pharmacology, 1993,Winter, Volume: 9, Issue:4

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Betaxolol; Carteolol; Drug Tolerance; Glaucoma; Humans; Intraocular Pressure; Levobunolol; Metipranolol; Ophthalmic Solutions; Timolol

1993
Topical ophthalmic beta-adrenergic blockade for the treatment of glaucoma and ocular hypertension.
    Journal of clinical pharmacology, 1994, Volume: 34, Issue:8

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Betaxolol; Carteolol; Glaucoma; Humans; Levobunolol; Metipranolol; Ocular Hypertension; Timolol

1994

Trials

14 trial(s) available for metipranolol and timolol

ArticleYear
Cardiovascular responses to metipranolol and timolol eyedrops in healthy volunteers.
    British journal of clinical pharmacology, 1989, Volume: 27, Issue:1

    Topics: Adult; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Intraocular Pressure; Male; Metipranolol; Middle Aged; Ophthalmic Solutions; Physical Exertion; Propanolamines; Timolol

1989
Efficacy and safety of the combination therapy Pilogel/beta-blocker: interim results.
    Documenta ophthalmologica. Advances in ophthalmology, 1989, Volume: 72, Issue:3-4

    Topics: Adrenergic beta-Antagonists; Aged; Betaxolol; Circadian Rhythm; Clinical Trials as Topic; Drug Therapy, Combination; Female; Gels; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Metipranolol; Middle Aged; Multicenter Studies as Topic; Ocular Hypertension; Pilocarpine; Pupil; Refraction, Ocular; Timolol

1989
A blind randomised cross-over trial comparing metipranolol 0.3% with timolol 0.25% in open-angle glaucoma: a pilot study.
    The British journal of ophthalmology, 1986, Volume: 70, Issue:1

    Topics: Aged; Clinical Trials as Topic; Double-Blind Method; Female; Glaucoma; Humans; Intraocular Pressure; Male; Metipranolol; Middle Aged; Propanolamines; Timolol

1986
[Immediate effect of a topical beta-blocker on breakup time].
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1986, Volume: 192, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Female; Humans; Intraocular Pressure; Levobunolol; Male; Metipranolol; Pindolol; Tears; Timolol

1986
[Therapeutic consequences of glaucoma treatment with different beta blockers in patients with obstructive respiratory tract diseases].
    Klinische Monatsblatter fur Augenheilkunde, 1986, Volume: 188, Issue:6

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Airway Resistance; Clinical Trials as Topic; Female; Glaucoma; Humans; Lung Diseases, Obstructive; Lung Volume Measurements; Male; Metipranolol; Middle Aged; Ophthalmic Solutions; Random Allocation; Timolol

1986
A single dose of three different ophthalmic beta-blockers antagonizes the chronotropic effect of isoproterenol in healthy volunteers.
    Clinical pharmacology and therapeutics, 1987, Volume: 41, Issue:6

    Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Carteolol; Double-Blind Method; Heart Rate; Humans; Intraocular Pressure; Isoproterenol; Male; Metipranolol; Ophthalmic Solutions; Random Allocation; Timolol

1987
[Mid-term results of a double-blind study comparing metipranolol to timolol in the treatment of primary open-angle glaucoma].
    Journal francais d'ophtalmologie, 1987, Volume: 10, Issue:6-7

    Topics: Double-Blind Method; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Metipranolol; Ophthalmic Solutions; Propanolamines; Time Factors; Timolol

1987
[Changes in lung function following administration of eyedrops containing timolol, metipranolol, pindolol and pilocarpine in healthy probands and patients with mild bronchial asthma].
    Klinische Wochenschrift, 1987, Oct-01, Volume: 65, Issue:19

    Topics: Airway Resistance; Asthma; Bronchial Spasm; Clinical Trials as Topic; Double-Blind Method; Humans; Lung Volume Measurements; Metipranolol; Ophthalmic Solutions; Pilocarpine; Pindolol; Propanolamines; Random Allocation; Timolol

1987
[Local anesthetic action of metipranolol as compared to timolol].
    Klinische Monatsblatter fur Augenheilkunde, 1983, Volume: 182, Issue:3

    Topics: Adult; Anesthetics, Local; Chemical Phenomena; Chemistry; Cornea; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Metipranolol; Middle Aged; Ophthalmology; Propanolamines; Random Allocation; Timolol

1983
[Comparative studies of initial pressure reduction using 0.3% metipranolol and 0.25% timolol in eyes with wide-angle glaucoma].
    Klinische Monatsblatter fur Augenheilkunde, 1983, Volume: 182, Issue:4

    Topics: Adult; Aged; Clinical Trials as Topic; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Metipranolol; Middle Aged; Propanolamines; Time Factors; Timolol

1983
[Metipranolol--a new beta-blocker].
    Klinische Monatsblatter fur Augenheilkunde, 1983, Volume: 182, Issue:6

    Topics: Adrenergic beta-Antagonists; Aged; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Metipranolol; Propanolamines; Timolol

1983
The influence of topical beta-blockers on the breakup time.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1984, Volume: 189, Issue:3

    Topics: Adult; Double-Blind Method; Glaucoma; Humans; Metipranolol; Ophthalmic Solutions; Propanolamines; Tears; Timolol

1984
Prepared association of metipranolol 0.1% + pilocarpine 2% and of timolol 0.5% + pilocarpine 2%. Comparison of clinical efficacy and topical tolerability in the treatment of patients affected by POAG tonometrically uncontrolled with beta-blocker alone (tw
    Acta ophthalmologica Scandinavica. Supplement, 1997, Issue:224

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Blood Pressure; Chronic Disease; Drug Therapy, Combination; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Metipranolol; Miotics; Ophthalmic Solutions; Pilocarpine; Timolol; Tonometry, Ocular; Treatment Outcome

1997
Comparison of the effects of 0.5% timolol maleate, 2% carteolol hydrochloride, and 0.3% metipranolol on intraocular pressure and perimetry findings and evaluation of their ocular and systemic effects.
    Journal of glaucoma, 2000, Volume: 9, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Carteolol; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Lipids; Male; Metipranolol; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Timolol; Treatment Outcome; Visual Field Tests; Visual Fields

2000

Other Studies

18 other study(ies) available for metipranolol and timolol

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Lipophilicity of basic drugs measured by hydrophilic interaction chromatography.
    Journal of medicinal chemistry, 2009, May-28, Volume: 52, Issue:10

    Topics: Chemistry, Pharmaceutical; Chromatography; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Pharmaceutical Preparations; Solubility; Technology, Pharmaceutical

2009
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Influence of the concentration of metipranolol eye drops on the drug concentration in human aqueous humour.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1991, Volume: 229, Issue:5

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Aqueous Humor; Cataract Extraction; Cornea; Dosage Forms; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Metipranolol; Middle Aged; Ophthalmic Solutions; Timolol

1991
Bronchial and cardiovascular effects of ocular topical B-antagonists in asthmatic subjects: comparison of timolol, carteolol, and metipranolol.
    Journal of clinical pharmacology, 1989, Volume: 29, Issue:2

    Topics: Adrenergic beta-Antagonists; Asthma; Carteolol; Female; Forced Expiratory Volume; Hemodynamics; Humans; Male; Metipranolol; Ophthalmic Solutions; Timolol; Vital Capacity

1989
[Effect of locally administered beta blockers in congenital and secondary glaucoma in childhood].
    Ceskoslovenska oftalmologie, 1985, Volume: 41, Issue:4

    Topics: Adolescent; Child; Child, Preschool; Female; Glaucoma; Humans; Infant; Male; Metipranolol; Propanolamines; Timolol

1985
[The effect of long-term administration of beta blockers and pilocarpine on the permeability of blood vessels in the iris as seen in fluoroangiography].
    Ceskoslovenska oftalmologie, 1985, Volume: 41, Issue:5

    Topics: Adult; Aged; Capillary Permeability; Female; Fluorescein Angiography; Glaucoma, Open-Angle; Humans; Iris; Male; Metipranolol; Middle Aged; Pilocarpine; Propanolamines; Time Factors; Timolol

1985
[Effect of commercial beta blockers and their combination with artificial tears on the duration of tear film stability].
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1987, Volume: 195, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Drug Combinations; Drug Stability; Humans; Levobunolol; Metipranolol; Polyvinyl Alcohol; Tears; Time Factors; Timolol

1987
[Comparative multicenter study of carteolol eyedrops with other beta blockers in 768 patients under normal conditions].
    Klinische Monatsblatter fur Augenheilkunde, 1988, Volume: 192, Issue:2

    Topics: Adrenergic beta-Antagonists; Carteolol; Drug Evaluation; Glaucoma; Humans; Intraocular Pressure; Metipranolol; Ophthalmic Solutions; Pindolol; Propanolamines; Time Factors; Timolol

1988
[Asthma and beta-blocker eye drops (timolol, metipranolol, carteolol). Inhibition of chronotropic effects of isoprenaline].
    Allergie et immunologie, 1988, Volume: 20, Issue:7

    Topics: Adult; Asthma; Blood Pressure; Carteolol; Heart Rate; Humans; Isoproterenol; Metipranolol; Middle Aged; Ophthalmic Solutions; Propanolamines; Respiration; Timolol

1988
[Comparison of the effect of timolol and metipranolol on axoplasmic transport in the optic nerve].
    Ceskoslovenska oftalmologie, 1984, Volume: 40, Issue:5

    Topics: Animals; Axonal Transport; Metipranolol; Optic Nerve; Propanolamines; Rats; Timolol

1984
Information on drop size needs to be eyed closely.
    American journal of hospital pharmacy, 1994, Dec-01, Volume: 51, Issue:23

    Topics: Cost Savings; Glaucoma; Humans; Metipranolol; Ophthalmic Solutions; Timolol

1994
Bilateral anterior uveitis associated with a brand of metipranolol.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1997, Volume: 115, Issue:3

    Topics: Adrenergic beta-Antagonists; Aged; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Metipranolol; Recurrence; Timolol; Uveitis, Anterior

1997
Effects of beta-blockers association with pilocarpine on rabbit intraocular pressure and heart rate.
    Pharmacological research, 1997, Volume: 35, Issue:4

    Topics: Adrenergic beta-Antagonists; Animals; Drug Combinations; Heart Rate; Intraocular Pressure; Male; Metipranolol; Muscarinic Agonists; Ophthalmic Solutions; Pilocarpine; Rabbits; Timolol

1997
[Contact allergy to eyedrops containing beta-blockers].
    Nederlands tijdschrift voor geneeskunde, 1998, May-02, Volume: 142, Issue:18

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Dermatitis, Allergic Contact; False Negative Reactions; Female; Glaucoma; Humans; Levobunolol; Male; Metipranolol; Middle Aged; Ophthalmic Solutions; Skin Tests; Timolol

1998
Topical ophthalmic beta blockers may cause release of histamine through cytotoxic effects on inflammatory cells.
    The British journal of ophthalmology, 2000, Volume: 84, Issue:9

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Basophils; Betaxolol; Carteolol; Cells, Cultured; Dose-Response Relationship, Drug; Histamine Release; Humans; L-Lactate Dehydrogenase; Leukocytes; Metipranolol; Timolol

2000
The beta-adrenoceptor antagonists metipranolol and timolol are retinal neuroprotectants: comparison with betaxolol.
    Experimental eye research, 2003, Volume: 76, Issue:4

    Topics: Adrenergic beta-Antagonists; Animals; Betaxolol; Calcium; Cell Hypoxia; Cell Survival; Cells, Cultured; Electroretinography; Metipranolol; Neuroprotective Agents; Rats; Rats, Wistar; Reperfusion Injury; Retina; Retinal Vessels; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium; Thy-1 Antigens; Timolol

2003
Inhibition of neutrophil migration and oxygen free radical release by metipranolol and timolol.
    Pharmacology, 2003, Volume: 68, Issue:4

    Topics: Adrenergic beta-Antagonists; Cell Survival; Cells, Cultured; Chemotaxis, Leukocyte; Free Radical Scavengers; Free Radicals; Humans; Metipranolol; Neutrophils; Oxygen; Respiratory Burst; Timolol

2003