Page last updated: 2024-08-21

methysergide and clozapine

methysergide has been researched along with clozapine in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19902 (8.33)18.7374
1990's11 (45.83)18.2507
2000's5 (20.83)29.6817
2010's5 (20.83)24.3611
2020's1 (4.17)2.80

Authors

AuthorsStudies
Hamblin, MW; Monsma, FJ; Shen, Y; Sibley, DR; Ward, RP1
Bull, D; den Daas, I; Foord, S; Goodson, S; Kilpatrick, G; Lee, M; Rees, S1
Hamblin, MW; Jose, PA; Metcalf, MA; Monsma, FJ; Shen, Y; Sibley, DR1
Amlaiky, N; Hen, R; Plassat, JL1
Druck, T; Hamblin, MW; Huebner, K; Khan, N; Kohen, R; Lachowicz, JE; Meltzer, HY; Metcalf, MA; Roth, BL; Sibley, DR1
Boess, FG; Meyer, V; Monsma, FJ; Sleight, AJ; Zwingelstein, C1
Baez, M; Kursar, JD; Lucaites, VL; Nelson, DL; Sasso, DA; Wainscott, DB1
Egan, CT; Herrick-Davis, K; Teitler, M1
Bentley, J; Boess, FG; Bös, M; Bourson, A; Riemer, C; Sleight, AJ1
Boess, FG; Monsma, FJ; Sleight, AJ1
Bach, T; Krobert, KA; Kvingedal, AM; Levy, FO; Syversveen, T1
Benwell, K; Bickerdike, M; Kennett, G; Knight, AR; Misra, A; Quirk, K; Revell, D1
Bandyopadhyaya, A; Rajagopalan, DR; Rajagopalan, P; Rajagopalan, R1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Jadhav, A; Kerns, E; Nguyen, K; Shah, P; Sun, H; Xu, X; Yan, Z; Yu, KR1
Kabir, M; Kerns, E; Nguyen, K; Shah, P; Sun, H; Wang, Y; Xu, X; Yu, KR1
Kabir, M; Kerns, E; Neyra, J; Nguyen, K; Nguyễn, ÐT; Shah, P; Siramshetty, VB; Southall, N; Williams, J; Xu, X; Yu, KR1
Barrett, JE; Mansbach, RS1
Dourish, CT1
Hietala, J; Kuoppamäki, M; Syvälahti, E1
Ling, L; McGuire, M; White, DP; Zhang, Y1
Huggins, JT; Sahn, SA1
Centurión, D; Gupta, S; MaassenVanDenBrink, A; Mehotra, S; Sánchez-López, A; Villalón, CM1
Adney, SK; Albizu, L; Baki, L; Brezina, V; Eltit, JM; Fabiato, A; Filizola, M; Fribourg, M; González-Maeso, J; Hatcher, C; Holloway, T; Li, Z; Logothetis, DE; MacKerell, AD; Mahajan, R; Moreno, JL; Park, G; Provasi, D; Ruta, JD; Sealfon, SC; Shim, J; Umali, A1

Reviews

1 review(s) available for methysergide and clozapine

ArticleYear
Drug-induced pleural disease.
    Clinics in chest medicine, 2004, Volume: 25, Issue:1

    Topics: Anti-Infective Agents, Urinary; Antimetabolites, Antineoplastic; Bleomycin; Cardiovascular Agents; Clozapine; Cyclophosphamide; Eosinophilia; Humans; Immunosuppressive Agents; Interleukin-2; Methotrexate; Methysergide; Nitrofurantoin; Penicillamine; Pleural Diseases; Pleural Effusion; Serotonin Antagonists

2004

Other Studies

23 other study(ies) available for methysergide and clozapine

ArticleYear
Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs.
    Molecular pharmacology, 1993, Volume: 43, Issue:3

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Blotting, Northern; Brain Chemistry; Cell Line; Cloning, Molecular; DNA; GTP-Binding Proteins; Lysergic Acid Diethylamide; Molecular Sequence Data; Polymerase Chain Reaction; Psychotropic Drugs; Rats; Receptors, Serotonin; RNA; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Transfection

1993
Cloning and characterisation of the human 5-HT5A serotonin receptor.
    FEBS letters, 1994, Dec-05, Volume: 355, Issue:3

    Topics: Amino Acid Sequence; Animals; Base Sequence; Brain Chemistry; Cloning, Molecular; Genome, Human; GTP-Binding Proteins; Humans; Mice; Molecular Sequence Data; Radioligand Assay; Receptors, Serotonin; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Serotonin; Tissue Distribution; Transfection

1994
Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype.
    The Journal of biological chemistry, 1993, Aug-25, Volume: 268, Issue:24

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Cell Line; Cell Membrane; Cloning, Molecular; Cyclic AMP; Gene Expression; Kidney Tubules, Proximal; Lysergic Acid Diethylamide; Molecular Sequence Data; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Radioligand Assay; Rats; Receptors, Serotonin; Recombinant Proteins; Serotonin; Transfection

1993
Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase.
    Molecular pharmacology, 1993, Volume: 44, Issue:2

    Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Base Sequence; Brain; Cloning, Molecular; Cyclic AMP; DNA; Drosophila; Enzyme Activation; Humans; Intestinal Mucosa; Mice; Molecular Sequence Data; Myocardium; Receptors, Serotonin; Sequence Homology, Amino Acid; Serotonin Antagonists; Serotonin Receptor Agonists

1993
Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor.
    Journal of neurochemistry, 1996, Volume: 66, Issue:1

    Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Antipsychotic Agents; Base Sequence; Brain Chemistry; Cell Line, Transformed; Chlorocebus aethiops; Chromosome Mapping; Chromosomes, Human, Pair 1; Cloning, Molecular; Clozapine; DNA, Complementary; Genes; Humans; Kinetics; Molecular Sequence Data; Open Reading Frames; Protein Conformation; Rats; Receptors, Serotonin; Recombinant Proteins; Sequence Alignment; Sequence Homology, Nucleic Acid; Serotonin Agents; Signal Transduction; Species Specificity

1996
Interaction of tryptamine and ergoline compounds with threonine 196 in the ligand binding site of the 5-hydroxytryptamine6 receptor.
    Molecular pharmacology, 1997, Volume: 52, Issue:3

    Topics: Amino Acid Sequence; Animals; Binding Sites; Cells, Cultured; Cloning, Molecular; Cricetinae; Dogs; Drug Interactions; Ergolines; Guinea Pigs; Humans; Kidney; Ligands; Lysergic Acid Diethylamide; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Rats; Receptors, Serotonin; Sequence Homology, Amino Acid; Serotonin; Threonine; Tryptamines

1997
[3H]Rauwolscine: an antagonist radioligand for the cloned human 5-hydroxytryptamine2b (5-HT2B) receptor.
    Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 357, Issue:1

    Topics: Adrenergic alpha-Antagonists; Benzofurans; Binding, Competitive; Cell Line; Cloning, Molecular; Humans; Imidazoles; Radioligand Assay; Receptor, Serotonin, 5-HT2B; Receptors, Serotonin; Serotonin Antagonists; Transfection; Tritium; Yohimbine

1998
Creation of a constitutively activated state of the 5-hydroxytryptamine2A receptor by site-directed mutagenesis: inverse agonist activity of antipsychotic drugs.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 286, Issue:1

    Topics: Animals; Antipsychotic Agents; COS Cells; Mutagenesis, Site-Directed; Phosphatidylinositols; Protein Conformation; Rats; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Structure-Activity Relationship

1998
The 5-hydroxytryptamine6 receptor-selective radioligand [3H]Ro 63-0563 labels 5-hydroxytryptamine receptor binding sites in rat and porcine striatum.
    Molecular pharmacology, 1998, Volume: 54, Issue:3

    Topics: Aminopyridines; Animals; Binding Sites; Corpus Striatum; HeLa Cells; Humans; Radioligand Assay; Rats; Receptors, Serotonin; Serotonin Antagonists; Species Specificity; Swine; Tritium

1998
Identification of residues in transmembrane regions III and VI that contribute to the ligand binding site of the serotonin 5-HT6 receptor.
    Journal of neurochemistry, 1998, Volume: 71, Issue:5

    Topics: Adenylyl Cyclases; Amino Acid Substitution; Binding Sites; Binding, Competitive; Cell Line; Cyclic AMP; Humans; Ligands; Lysergic Acid Diethylamide; Mutagenesis, Site-Directed; Mutation; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists

1998
The cloned human 5-HT7 receptor splice variants: a comparative characterization of their pharmacology, function and distribution.
    Naunyn-Schmiedeberg's archives of pharmacology, 2001, Volume: 363, Issue:6

    Topics: Adenylyl Cyclases; Alternative Splicing; Binding, Competitive; Brain; Cell Line; Cloning, Organism; Genetic Variation; Humans; Radioligand Assay; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tissue Distribution

2001
Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors.
    Naunyn-Schmiedeberg's archives of pharmacology, 2004, Volume: 370, Issue:2

    Topics: Binding Sites; Binding, Competitive; Cell Line; Humans; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Recombinant Proteins; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists

2004
The synthesis and comparative receptor binding affinities of novel, isomeric pyridoindolobenzazepine scaffolds.
    Bioorganic & medicinal chemistry letters, 2014, Jan-15, Volume: 24, Issue:2

    Topics: Benzodiazepinones; Isomerism; Protein Binding; Protein Structure, Tertiary; Receptors, Cell Surface

2014
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Highly predictive and interpretable models for PAMPA permeability.
    Bioorganic & medicinal chemistry, 2017, 02-01, Volume: 25, Issue:3

    Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Humans; Models, Biological; Organic Chemicals; Regression Analysis; Support Vector Machine

2017
Predictive models of aqueous solubility of organic compounds built on A large dataset of high integrity.
    Bioorganic & medicinal chemistry, 2019, 07-15, Volume: 27, Issue:14

    Topics: Drug Discovery; Organic Chemicals; Pharmaceutical Preparations; Solubility

2019
Retrospective assessment of rat liver microsomal stability at NCATS: data and QSAR models.
    Scientific reports, 2020, 11-26, Volume: 10, Issue:1

    Topics: Animals; Computer Simulation; Databases, Factual; Drug Discovery; High-Throughput Screening Assays; Liver; Machine Learning; Male; Microsomes, Liver; National Center for Advancing Translational Sciences (U.S.); Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Rats; Rats, Sprague-Dawley; Retrospective Studies; United States

2020
Discriminative stimulus properties of buspirone in the pigeon.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 240, Issue:2

    Topics: Animals; Apomorphine; Buspirone; Clozapine; Columbidae; Discrimination Learning; Haloperidol; Methysergide; Midazolam; Pyrimidines; Serotonin

1987
Behavioural effects of acute and chronic beta-phenylethylamine administration in the rat: evidence for the involvement of 5-hydroxytryptamine.
    Neuropharmacology, 1981, Volume: 20, Issue:11

    Topics: Animals; Behavior, Animal; Clozapine; Crowding; Haloperidol; Male; Methysergide; Mianserin; Phenethylamines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Serotonin; Serotonin

1981
Clozapine and N-desmethylclozapine are potent 5-HT1C receptor antagonists.
    European journal of pharmacology, 1993, Apr-15, Volume: 245, Issue:2

    Topics: Animals; Choroid Plexus; Clozapine; In Vitro Techniques; Male; Methysergide; Phosphatidylinositols; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Serotonin Antagonists

1993
Serotonin receptor subtypes required for ventilatory long-term facilitation and its enhancement after chronic intermittent hypoxia in awake rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2004, Volume: 286, Issue:2

    Topics: Animals; Chronic Disease; Clozapine; Hypoxia; Ketanserin; Male; Methysergide; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Respiration; Respiratory Mechanics; Serotonin Antagonists

2004
Potential vascular alpha1-adrenoceptor blocking properties of an array of 5-HT receptor ligands in the rat.
    European journal of pharmacology, 2006, Mar-27, Volume: 535, Issue:1-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Buspirone; Clozapine; Decerebrate State; Dose-Response Relationship, Drug; Drug Interactions; Ergotamine; Heart Rate; Ketanserin; Lisuride; Male; Metergoline; Methiothepin; Methysergide; Phenylephrine; Piperazines; Pizotyline; Prazosin; Pyridines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Serotonin Antagonists; Serotonin Receptor Agonists; Yohimbine

2006
Decoding the signaling of a GPCR heteromeric complex reveals a unifying mechanism of action of antipsychotic drugs.
    Cell, 2011, Nov-23, Volume: 147, Issue:5

    Topics: Amphetamines; Animals; Antipsychotic Agents; Clozapine; Dimerization; Dose-Response Relationship, Drug; Frontal Lobe; Methysergide; Mice; Oocytes; Potassium Channels, Inwardly Rectifying; Receptors, Adrenergic, beta-2; Receptors, Metabotropic Glutamate; Signal Transduction; Xenopus

2011