Page last updated: 2024-08-21

methylthioinosine and methotrexate

methylthioinosine has been researched along with methotrexate in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19906 (75.00)18.7374
1990's2 (25.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Henderson, JF; Lowe, JK1
Christopherson, RI; Lyons, SD; Phillips, L; Sant, ME1
Martin, DS1
Martin, DS; Nayak, R; Sawyer, RC; Spiegelman, S; Stolfi, RL; Woodcock, T; Young, CW1
Egan, EM; Kufe, DW; Major, PP; Sargent, L1
Blechman, WJ; Kim, K; Pardee, AB; Riddle, VG1
Fox, M; McMillan, S1
Aarbakke, J; Fuskevaag, OM; Giverhaug, T1

Reviews

1 review(s) available for methylthioinosine and methotrexate

ArticleYear
An overview of thymidine.
    Cancer, 1980, Mar-15, Volume: 45, Issue:5 Suppl

    Topics: Animals; Antineoplastic Agents; Bone Marrow; Clinical Trials as Topic; Cytarabine; DNA, Neoplasm; Drug Therapy, Combination; Fluorouracil; Humans; Methotrexate; Methylthioinosine; Mice; Neoplasms; Thymidine

1980

Trials

1 trial(s) available for methylthioinosine and methotrexate

ArticleYear
An overview of thymidine.
    Cancer, 1980, Mar-15, Volume: 45, Issue:5 Suppl

    Topics: Animals; Antineoplastic Agents; Bone Marrow; Clinical Trials as Topic; Cytarabine; DNA, Neoplasm; Drug Therapy, Combination; Fluorouracil; Humans; Methotrexate; Methylthioinosine; Mice; Neoplasms; Thymidine

1980

Other Studies

7 other study(ies) available for methylthioinosine and methotrexate

ArticleYear
Enhancement by caffeine of the growth inhibitory effects of antimetabolites in lymphoma L5178Y cells.
    Biochemical pharmacology, 1977, Aug-15, Volume: 26, Issue:16

    Topics: Antimetabolites; Caffeine; Cell Division; Cells, Cultured; Deoxyadenosines; Drug Synergism; Hydroxyurea; In Vitro Techniques; Lymphoma; Methotrexate; Methylthioinosine; Mycophenolic Acid; Neoplasms, Experimental; Time Factors

1977
Antifolates induce inhibition of amido phosphoribosyltransferase in leukemia cells.
    The Journal of biological chemistry, 1992, Jun-05, Volume: 267, Issue:16

    Topics: Amidophosphoribosyltransferase; Aminoimidazole Carboxamide; Animals; Azaserine; Folic Acid Antagonists; Leukemia, Experimental; Methotrexate; Methylthioinosine; Mice; Purines; Pyrimidines; Ribonucleotides; Tumor Cells, Cultured

1992
Cancer chemotherapy: past is prologue.
    The Mount Sinai journal of medicine, New York, 1985, Volume: 52, Issue:6

    Topics: 6-Aminonicotinamide; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Female; Fluorouracil; Humans; Male; Mammary Neoplasms, Experimental; Methotrexate; Methylthioinosine; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Phosphonoacetic Acid

1985
Modulation of 5-FU metabolism in human MCF-7 breast carcinoma cells.
    Cancer chemotherapy and pharmacology, 1982, Volume: 8, Issue:1

    Topics: Breast Neoplasms; Cells, Cultured; Female; Fluorouracil; Humans; Methotrexate; Methylthioinosine; RNA, Neoplasm

1982
Basis of observed resistance of L1210 leukemia in mice: methotrexate, 6-thioguanine, 6-methylmercaptopurine riboside, 6-mercaptopurine, 5-fluorouracil, and 1-beta-D-arabinofuranosylcytosine administered in different combinations.
    Cancer research, 1981, Volume: 41, Issue:11 Pt 1

    Topics: Animals; Antineoplastic Agents; Biotransformation; Cell Line; Cytarabine; Drug Evaluation, Preclinical; Drug Interactions; Drug Resistance; Drug Therapy, Combination; Fluorouracil; Leukemia L1210; Male; Mercaptopurine; Methotrexate; Methylthioinosine; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Thioguanine

1981
Effects of metabolic inhibitors on cell lethality and mutation induction in Chinese hamster cells. I. Inhibitors of de novo purine synthesis and a comparison with the effects of caffeine.
    Chemico-biological interactions, 1981, Volume: 36, Issue:1

    Topics: Animals; Azaserine; Caffeine; Cell Line; Cricetinae; Cricetulus; Ethyl Methanesulfonate; Lung; Methotrexate; Methylthioinosine; Mutation; Purines; Ultraviolet Rays

1981
Methotrexate increases red blood cell concentrations of 6-methylmercaptopurine ribonucleotide in rats in vivo.
    Cancer chemotherapy and pharmacology, 1997, Volume: 40, Issue:4

    Topics: Animals; Erythrocytes; Guanine Nucleotides; Male; Mercaptopurine; Methotrexate; Methylthioinosine; Methyltransferases; Nucleic Acid Synthesis Inhibitors; Rats; Rats, Wistar; Thionucleotides

1997