methylthioinosine has been researched along with fluorouracil in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (50.00) | 18.7374 |
| 1990's | 6 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Colofiore, JR; Koutcher, JA; Martin, DS; Nord, LD; Stolfi, RL | 1 |
| Colofiore, J; Comis, RL; Hoffman, J; Hudes, GR; LaCreta, FP; Martin, DS; O'Dwyer, PJ; Ozols, RF; Walczak, J | 1 |
| Calabresi, P; Crabtree, GW; Cummings, FJ; Murray, C; Spremulli, EN; Weitberg, AB; Wiemann, MC | 1 |
| Martin, DS | 1 |
| Kufe, DW; Peters, WP; Weiss, G | 1 |
| Martin, DS; Nayak, R; Sawyer, RC; Spiegelman, S; Stolfi, RL; Woodcock, T; Young, CW | 1 |
| Egan, EM; Kufe, DW; Major, PP; Sargent, L | 1 |
| Blechman, WJ; Kim, K; Pardee, AB; Riddle, VG | 1 |
| O'Dwyer, PJ | 1 |
| Green, F; Hoffman, JP; O'Dwyer, PJ; Redei, I; Scher, R; Weiner, LM | 1 |
| Brennan, J; Greene, F; Hageboutros, A; Hudes, GR; LaCreta, FP; O'Dwyer, PJ | 1 |
| Alfieri, AA; Koutcher, JA; Martin, DS; Matei, C; Thaler, H | 1 |
2 review(s) available for methylthioinosine and fluorouracil
| Article | Year |
|---|---|
An overview of thymidine.
Topics: Animals; Antineoplastic Agents; Bone Marrow; Clinical Trials as Topic; Cytarabine; DNA, Neoplasm; Drug Therapy, Combination; Fluorouracil; Humans; Methotrexate; Methylthioinosine; Mice; Neoplasms; Thymidine | 1980 |
Biochemical modulation as an approach to reversal of antimetabolite resistance.
Topics: Antimetabolites, Antineoplastic; Aspartic Acid; Clinical Trials as Topic; Colorectal Neoplasms; Drug Design; Drug Resistance, Multiple; Fluorouracil; Humans; Interferons; Methylthioinosine; Multicenter Studies as Topic; Phosphonoacetic Acid; Purines; Pyrimidines; Thymidylate Synthase; Tumor Cells, Cultured | 1994 |
4 trial(s) available for methylthioinosine and fluorouracil
| Article | Year |
|---|---|
Phase I trial of fluorouracil modulation by N-phosphonacetyl-L-aspartate and 6-methylmercaptopurine riboside: optimization of 6-methylmercaptopurine riboside dose and schedule through biochemical analysis of sequential tumor biopsy specimens.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Biopsy; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation; Drug Interactions; Female; Fluorouracil; Humans; Male; Methylthioinosine; Middle Aged; Neoplasms; Phosphonoacetic Acid; Phosphoribosyl Pyrophosphate | 1991 |
An overview of thymidine.
Topics: Animals; Antineoplastic Agents; Bone Marrow; Clinical Trials as Topic; Cytarabine; DNA, Neoplasm; Drug Therapy, Combination; Fluorouracil; Humans; Methotrexate; Methylthioinosine; Mice; Neoplasms; Thymidine | 1980 |
Phase II trial of PALA and 6-methylmercaptopurine riboside (MMPR) in combination with 5-fluorouracil in advanced pancreatic cancer.
Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartate Carbamoyltransferase; Aspartic Acid; Female; Fluorouracil; Humans; Male; Methylthioinosine; Middle Aged; Pancreatic Neoplasms; Phosphonoacetic Acid | 1994 |
Phase I trial of fluorouracil modulation by N-phosphonacetyl-L-aspartate and 6-methylmercaptopurine ribonucleoside (MMPR), and leucovorin in patients with advanced cancer.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Aspartic Acid; Colorectal Neoplasms; Drug Interactions; Female; Fluorouracil; Humans; Leucovorin; Male; Methylthioinosine; Middle Aged; Phosphonoacetic Acid | 1997 |
7 other study(ies) available for methylthioinosine and fluorouracil
| Article | Year |
|---|---|
Biochemical modulation of tumor cell energy: regression of advanced spontaneous murine breast tumors with a 5-fluorouracil-containing drug combination.
Topics: 6-Aminonicotinamide; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Female; Fluorouracil; Mammary Neoplasms, Experimental; Methylthioinosine; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Orotic Acid; Phosphonoacetic Acid; Phosphoribosyl Pyrophosphate | 1992 |
Phase I trial of the combination of 6-methylmercaptopurine riboside and 5-fluorouracil.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Drug Evaluation; Drug Therapy, Combination; Female; Fluorouracil; Humans; Inosine; Male; Methylthioinosine; Middle Aged | 1988 |
Cancer chemotherapy: past is prologue.
Topics: 6-Aminonicotinamide; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Female; Fluorouracil; Humans; Male; Mammary Neoplasms, Experimental; Methotrexate; Methylthioinosine; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Phosphonoacetic Acid | 1985 |
Phase-I trial of combination therapy with continuous-infusion MMPR and continuous-infusion 5-FU.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Drug Evaluation; Female; Fluorouracil; Humans; Inosine; Male; Methylthioinosine; Middle Aged; Neoplasms; Phosphoribosyl Pyrophosphate; RNA, Neoplasm | 1984 |
Modulation of 5-FU metabolism in human MCF-7 breast carcinoma cells.
Topics: Breast Neoplasms; Cells, Cultured; Female; Fluorouracil; Humans; Methotrexate; Methylthioinosine; RNA, Neoplasm | 1982 |
Basis of observed resistance of L1210 leukemia in mice: methotrexate, 6-thioguanine, 6-methylmercaptopurine riboside, 6-mercaptopurine, 5-fluorouracil, and 1-beta-D-arabinofuranosylcytosine administered in different combinations.
Topics: Animals; Antineoplastic Agents; Biotransformation; Cell Line; Cytarabine; Drug Evaluation, Preclinical; Drug Interactions; Drug Resistance; Drug Therapy, Combination; Fluorouracil; Leukemia L1210; Male; Mercaptopurine; Methotrexate; Methylthioinosine; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Thioguanine | 1981 |
Radiation enhancement by biochemical modulation and 5-fluorouracil.
Topics: 6-Aminonicotinamide; Animals; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Cell Division; Combined Modality Therapy; Fluorouracil; Mammary Neoplasms, Animal; Methylthioinosine; Mice; Radiation-Sensitizing Agents; Radiotherapy Dosage; Time Factors | 1997 |