Page last updated: 2024-08-21

methylthioinosine and azathioprine

methylthioinosine has been researched along with azathioprine in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (15.38)18.2507
2000's5 (38.46)29.6817
2010's4 (30.77)24.3611
2020's2 (15.38)2.80

Authors

AuthorsStudies
Sandborn, WJ1
Aarbakke, J; Bergan, S; Giverhaug, T; Loennechen, T; Rugstad, HE1
Dubinsky, MC1
Griffiths, AM1
Dejaco, C; Harrer, M; Mantl, M; Miehsler, W; Reinisch, W; Schaeffeler, E; Schneider, B; Schwab, M; Teml, A; Vogelsang, H1
Gisbert, JP; González-Lama, Y; Maté, J1
Hoover, S; Striker, R1
Greenley, RN; Hommel, KA; Kunz, JH1
Angelberger, S; Heinkele, G; Hofmann, U; Jaeger, S; Lichtenberger, C; Reinisch, W; Schaeffeler, E; Schwab, M1
Adriani, A; Agnesod, D; Astegiano, M; Canaparo, R; D'Avolio, A; De Nicolò, A; Di Perri, G; Riganò, D; Rizzetto, M; Simiele, M1
Almer, S; Andersson, D; Hindorf, U; Peterson, C; Vikingsson, S1
Bai, YJ; Li, Y; Miao, Q; Su, ZZ; Wang, LL; Yan, L; Zhang, JL; Zou, YG1
Andrews, JM; Bampton, P; Barnes, A; Bishara, M; Connor, S; Gounder, M; Grafton, R; Leach, P; Lynch, KD; Mountifield, R; Ng, W; Ooi, SJ; Parthasarathy, N; Sechi, A; van Langenberg, D1

Reviews

1 review(s) available for methylthioinosine and azathioprine

ArticleYear
[Monitoring of thiopurine methyltransferase and thiopurine metabolites to optimize azathioprine therapy in inflammatory bowel disease].
    Gastroenterologia y hepatologia, 2006, Volume: 29, Issue:9

    Topics: Antimetabolites; Azathioprine; Drug Monitoring; Genotype; Humans; Immunosuppressive Agents; Mercaptopurine; Methylthioinosine; Methyltransferases; Phenotype; Thioguanine

2006

Trials

1 trial(s) available for methylthioinosine and azathioprine

ArticleYear
A prospective, open-label trial of 6-thioguanine in patients with ulcerative or indeterminate colitis.
    Scandinavian journal of gastroenterology, 2005, Volume: 40, Issue:10

    Topics: Adult; Aged; Anti-Inflammatory Agents; Azathioprine; Biomarkers; C-Reactive Protein; Colitis, Ulcerative; Dose-Response Relationship, Drug; Endoscopy, Gastrointestinal; Female; Genotype; Guanine Nucleotides; Humans; Male; Mercaptopurine; Methylthioinosine; Methyltransferases; Middle Aged; Orosomucoid; Patient Compliance; Prospective Studies; Quality of Life; Thioguanine; Thionucleotides; Treatment Outcome

2005

Other Studies

11 other study(ies) available for methylthioinosine and azathioprine

ArticleYear
6-MP metabolite levels: a potential guide to Crohn's disease therapy.
    Gastroenterology, 1997, Volume: 113, Issue:2

    Topics: Antimetabolites; Antimetabolites, Antineoplastic; Azathioprine; Chromatography, High Pressure Liquid; Crohn Disease; Humans; Mercaptopurine; Methylthioinosine; Thioguanine

1997
Analysis of methylated 6-mercaptopurine metabolites in human red blood cells: comparison of two methods.
    Therapeutic drug monitoring, 1997, Volume: 19, Issue:6

    Topics: Azathioprine; Chromatography, High Pressure Liquid; Erythrocytes; Humans; Hydrolysis; Kidney Transplantation; Mercaptopurine; Methylation; Methylthioinosine

1997
Monitoring of AZA/6-MP treatment in children with IBD is necessary.
    Inflammatory bowel diseases, 2003, Volume: 9, Issue:6

    Topics: Azathioprine; Child; Drug Monitoring; Guanine Nucleotides; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mercaptopurine; Methylthioinosine; Methyltransferases; Polymorphism, Genetic; Thionucleotides

2003
Monitoring of azathioprine/6-mercaptopurine treatment in children with IBD is not necessary.
    Inflammatory bowel diseases, 2003, Volume: 9, Issue:6

    Topics: Azathioprine; Child; Drug Monitoring; Guanine Nucleotides; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mercaptopurine; Methylthioinosine; Methyltransferases; Polymorphism, Genetic; Thionucleotides

2003
Thiopurines inhibit bovine viral diarrhea virus production in a thiopurine methyltransferase-dependent manner.
    The Journal of general virology, 2008, Volume: 89, Issue:Pt 4

    Topics: Adenosine; Animals; Antiviral Agents; Azathioprine; Bovine Virus Diarrhea-Mucosal Disease; Cattle; Cell Line; Diarrhea Viruses, Bovine Viral; Methylthioinosine; Methyltransferases; Virus Replication

2008
Health-related quality of life of youth with inflammatory bowel disease: a comparison with published data using the PedsQL 4.0 generic core scales.
    Inflammatory bowel diseases, 2010, Volume: 16, Issue:6

    Topics: Adolescent; Adult; Child; Female; Humans; Inflammatory Bowel Diseases; Interpersonal Relations; Male; Mercaptopurine; Mesalamine; Methylthioinosine; Middle Aged; Parents; Quality of Life; Self Concept; Severity of Illness Index; Sickness Impact Profile; Social Adjustment; Thioguanine

2010
Simultaneous quantification of eleven thiopurine nucleotides by liquid chromatography-tandem mass spectrometry.
    Analytical chemistry, 2012, Feb-07, Volume: 84, Issue:3

    Topics: Azathioprine; Chromatography, High Pressure Liquid; Crohn Disease; Erythrocytes; Guanine Nucleotides; Humans; Immunosuppressive Agents; Isotope Labeling; Mercaptopurine; Methylthioinosine; Tandem Mass Spectrometry; Thionucleotides

2012
UPLC-MS/MS method for quantification of the azathioprine metabolites 6-mercaptoguanosine and 6-methylmercaptopurine riboside in peripheral blood mononuclear cells.
    Journal of pharmaceutical and biomedical analysis, 2014, Volume: 98

    Topics: Azathioprine; Chromatography, High Pressure Liquid; Guanosine; Humans; Inflammatory Bowel Diseases; Leukocytes, Mononuclear; Methylthioinosine; Tandem Mass Spectrometry; Thionucleosides

2014
Novel assay to improve therapeutic drug monitoring of thiopurines in inflammatory bowel disease.
    Journal of Crohn's & colitis, 2014, Volume: 8, Issue:12

    Topics: Adolescent; Adult; Aged; Azathioprine; Cross-Sectional Studies; Drug Monitoring; Erythrocytes; Female; GTP Phosphohydrolases; Guanine Nucleotides; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Male; Mercaptopurine; Methylthioinosine; Middle Aged; Thioguanine; Thioinosine; Thionucleotides; Young Adult

2014
Highly sensitive and rapid determination of azathioprine metabolites in whole blood lysate by liquid chromatography-tandem mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2020, Jan-01, Volume: 1136

    Topics: Adult; Azathioprine; Chromatography, High Pressure Liquid; Drug Monitoring; Female; Guanine Nucleotides; Humans; Limit of Detection; Linear Models; Male; Methylthioinosine; Middle Aged; Reproducibility of Results; Tandem Mass Spectrometry; Thionucleotides

2020
Proactive Metabolite Testing in Patients on Thiopurine May Yield Long-Term Clinical Benefits in Inflammatory Bowel Disease.
    Digestive diseases and sciences, 2023, Volume: 68, Issue:3

    Topics: Azathioprine; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mercaptopurine; Methylthioinosine; Retrospective Studies

2023