methylthio-adp has been researched along with uridine triphosphate in 19 studies
| Studies (methylthio-adp) | Trials (methylthio-adp) | Recent Studies (post-2010) (methylthio-adp) | Studies (uridine triphosphate) | Trials (uridine triphosphate) | Recent Studies (post-2010) (uridine triphosphate) |
|---|---|---|---|---|---|
| 146 | 2 | 43 | 2,423 | 20 | 331 |
| Protein | Taxonomy | methylthio-adp (IC50) | uridine triphosphate (IC50) |
|---|---|---|---|
| P2Y purinoceptor 2 | Mus musculus (house mouse) | 1.51 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (15.79) | 18.2507 |
| 2000's | 13 (68.42) | 29.6817 |
| 2010's | 2 (10.53) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Jacobson, KA; Jarvis, MF; Williams, M | 1 |
| Fischer, B; Lévesque, SA; Nahum, V; Reiser, G; Sévigny, J; Tulapurkar, M | 1 |
| Greve, H; Kassack, MU; Kehraus, S; König, GM; Krick, A; Meis, S; Wright, AD | 1 |
| Camden, J; Eliahu, SE; Fischer, B; Gélinas, S; Lecka, J; Sévigny, J; Weisman, GA | 1 |
| Camden, J; Fischer, B; Weisman, GA; Yelovitch, S | 1 |
| Baqi, Y; Malik, EM; Müller, CE; Namasivayam, V; Neumann, A; Rafehi, M; Wiese, M | 1 |
| Barnard, EA; Burnstock, G; King, BF; Simon, J; Webb, TE | 1 |
| Duchêne, AD; Takeda, K | 1 |
| Hourani, SM; Park, HS | 1 |
| Fam, SR; Gallagher, CJ; Salter, MW | 1 |
| Dixon, CJ | 1 |
| Chambers, JK; Emson, PC; Moore, DJ; Murdock, PR | 1 |
| Edvinsson, L; Erlinge, D; Hou, M; Malmsjö, M; Pendergast, W | 1 |
| Fam, SR; Gallagher, CJ; Kalia, LV; Salter, MW | 1 |
| Giron, R; Mizumura, K; Nakamura, R; Sato, J; Yajima, H | 1 |
| Burnstock, G; Cowen, T; Knight, GE; Wallace, A | 1 |
| Burnstock, G; Chiaravalli, AM; Frigo, G; Giaroni, C; Knight, GE; Lecchini, S; Zanetti, E | 1 |
| Boarder, MR; Dixon, CJ; Hall, JF; Luo, Y; White, PJ | 1 |
| Delicado, EG; Gil-Redondo, JC; Iturri, J; Miras-Portugal, MT; Ortega, F; Pérez-Sen, R; Toca-Herrera, JL; Weber, A | 1 |
1 review(s) available for methylthio-adp and uridine triphosphate
| Article | Year |
|---|---|
Purine and pyrimidine (P2) receptors as drug targets.
Topics: Adenosine Triphosphate; Animals; Drug Design; Humans; Ligands; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyrimidines; Receptors, Purinergic P2; Uridine Triphosphate | 2002 |
18 other study(ies) available for methylthio-adp and uridine triphosphate
| Article | Year |
|---|---|
Diadenosine and diuridine poly(borano)phosphate analogues: synthesis, chemical and enzymatic stability, and activity at P2Y1 and P2Y2 receptors.
Topics: Adenosine; Animals; Boranes; Cell Line; Chlorocebus aethiops; Crystallography, X-Ray; Dinucleoside Phosphates; Drug Stability; Humans; Hydrolysis; Phosphoric Diester Hydrolases; Purinergic P2 Receptor Agonists; Pyrophosphatases; Rats; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y2; Uridine | 2006 |
New iantherans from the marine sponge Ianthella quadrangulata: novel agonists of the P2Y(11) receptor.
Topics: Animals; Benzofurans; Calcium; Cell Line, Tumor; Humans; Ligands; Models, Molecular; Porifera; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2; Structure-Activity Relationship; Sulfuric Acid Esters; Tyrosine | 2007 |
Identification of hydrolytically stable and selective P2Y(1) receptor agonists.
Topics: Adenosine Triphosphatases; Animals; Biomimetics; Cell Line, Tumor; Drug Design; Gastric Juice; Humans; Hydrogen-Ion Concentration; Hydrolysis; Nucleotides; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2Y1; Substrate Specificity; Temperature | 2009 |
Boranophosphate isoster controls P2Y-receptor subtype selectivity and metabolic stability of dinucleoside polyphosphate analogues.
Topics: Animals; Boranes; Calcium; Cell Line, Tumor; Dinucleoside Phosphates; Drug Stability; Humans; Hydrolysis; Models, Molecular; Molecular Conformation; Phosphoric Diester Hydrolases; Purinergic P2Y Receptor Agonists; Pyrophosphatases; Receptors, Purinergic P2Y; Stereoisomerism; Structure-Activity Relationship; Turkey | 2012 |
Molecular Recognition of Agonists and Antagonists by the Nucleotide-Activated G Protein-Coupled P2Y
Topics: Cell Line, Tumor; Crystallography, X-Ray; Humans; Models, Molecular; Mutagenesis, Site-Directed; Purinergic P2Y Receptor Agonists; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y2; Sequence Homology, Amino Acid; Spectrum Analysis | 2017 |
Characterisation of a recombinant P2Y purinoceptor.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Animals; Brain; Cell Line; Electrophysiology; Inositol Phosphates; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Recombinant Proteins; Suramin; Thionucleotides; Triazines; Uridine Triphosphate; Xenopus | 1995 |
P2Y- and P2U-mediated increases in internal calcium in single bovine aortic endothelial cells in primary culture.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Cattle; Cells, Cultured; Ion Transport; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Thionucleotides; Uridine Triphosphate | 1997 |
Differential effects of adenine nucleotide analogues on shape change and aggregation induced by adnosine 5-diphosphate (ADP) in human platelets.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Blood Platelets; Cell Size; Dose-Response Relationship, Drug; Humans; Platelet Aggregation; Suramin; Thionucleotides; Trypanocidal Agents; Uridine Triphosphate | 1999 |
P2Y(1) purinoceptor-mediated Ca(2+) signaling and Ca(2+) wave propagation in dorsal spinal cord astrocytes.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Astrocytes; Calcium; Calcium Signaling; Cells, Cultured; Embryo, Mammalian; Female; Posterior Horn Cells; Pregnancy; Rats; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; RNA, Messenger; Thionucleotides; Uridine Triphosphate | 2000 |
Evidence that 2-methylthioATP and 2-methylthioADP are both agonists at the rat hepatocyte P2Y(1) receptor.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium Signaling; Liver; Male; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P2Y1; Thionucleotides; Uridine Triphosphate | 2000 |
Human Ntera-2/D1 neuronal progenitor cells endogenously express a functional P2Y1 receptor.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Antineoplastic Agents; Blotting, Western; Calcium; Cell Membrane; Cells, Cultured; Cyclic AMP; Fluorescence; GTP-Binding Protein alpha Subunits, Gq-G11; Heterotrimeric GTP-Binding Proteins; Humans; Membrane Proteins; Mitogen-Activated Protein Kinases; Neurons; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Receptors, Purinergic P2Y2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stem Cells; Suramin; Thionucleotides; Uridine Triphosphate | 2002 |
The stable pyrimidines UDPbetaS and UTPgammaS discriminate between contractile cerebrovascular P2 receptors.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Basilar Artery; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; In Vitro Techniques; Potassium; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2X; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thionucleotides; Uridine Diphosphate; Uridine Triphosphate; Vasoconstriction | 2003 |
Differential frequency dependence of P2Y1- and P2Y2- mediated Ca 2+ signaling in astrocytes.
Topics: Adenosine Diphosphate; Animals; Astrocytes; Astrocytoma; Biological Clocks; Calcium; Calcium Signaling; Cells, Cultured; Feedback, Physiological; Fluorescent Dyes; Humans; Mutagenesis, Site-Directed; Protein Kinase C; Purinergic P2 Receptor Agonists; Rats; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y2; Spectrometry, Fluorescence; Structure-Activity Relationship; Thionucleotides; Uridine Triphosphate | 2003 |
Inhibitory, facilitatory, and excitatory effects of ATP and purinergic receptor agonists on the activity of rat cutaneous nociceptors in vitro.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antineoplastic Agents; Electric Stimulation; Female; Hot Temperature; Nerve Fibers, Unmyelinated; Nociceptors; Organ Culture Techniques; Purinergic Agonists; Rats; Rats, Inbred Lew; Skin; Stimulation, Chemical; Thionucleotides; Uridine Triphosphate | 2005 |
Changes in purinergic signalling in developing and ageing rat tail artery: importance for temperature control.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Aging; Animals; Arteries; Dose-Response Relationship, Drug; Electric Stimulation; Immunohistochemistry; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Norepinephrine; Prazosin; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Regional Blood Flow; Signal Transduction; Suramin; Tail; Thionucleotides; Uridine Triphosphate | 2006 |
Postnatal development of P2 receptors in the murine gastrointestinal tract.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Age Factors; Analysis of Variance; Animals; Animals, Newborn; Blotting, Western; Dose-Response Relationship, Drug; Female; Gastrointestinal Tract; Gene Expression Regulation, Developmental; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Muscle, Smooth; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Thionucleotides; Uridine Triphosphate | 2006 |
A role for Akt in epidermal growth factor-stimulated cell cycle progression in cultured hepatocytes: generation of a hyperproliferative window after adenoviral expression of constitutively active Akt.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenoviridae; Animals; Cell Cycle; Cell Proliferation; Cell Survival; Epidermal Growth Factor; Glycogen Phosphorylase; Hepatocytes; Inositol Phosphates; Insulin; Male; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; S Phase; Thionucleotides; TOR Serine-Threonine Kinases; Transfection; Uridine Diphosphate; Uridine Triphosphate | 2007 |
Nucleotides-Induced Changes in the Mechanical Properties of Living Endothelial Cells and Astrocytes, Analyzed by Atomic Force Microscopy.
Topics: Adenosine Diphosphate; Astrocytes; Human Umbilical Vein Endothelial Cells; Humans; Microscopy, Atomic Force; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Signal Transduction; Thionucleotides; Uridine Triphosphate | 2021 |