Compounds > methylthio-adp
Page last updated: 2024-09-03

methylthio-adp and uridine diphosphate

methylthio-adp has been researched along with uridine diphosphate in 8 studies

Compound Research Comparison

Studies
(methylthio-adp)		Trials
(methylthio-adp)		Recent Studies (post-2010)
(methylthio-adp)		Studies
(uridine diphosphate)		Trials
(uridine diphosphate)		Recent Studies (post-2010) (uridine diphosphate)
1462431,1644536

Protein Interaction Comparison

ProteinTaxonomymethylthio-adp (IC50)uridine diphosphate (IC50)
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunitHomo sapiens (human)1.8

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (62.50)29.6817
2010's2 (25.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Jacobson, KA; Jarvis, MF; Williams, M1
Camden, J; Eliahu, SE; Fischer, B; Gélinas, S; Lecka, J; Sévigny, J; Weisman, GA1
Camden, J; Fischer, B; Weisman, GA; Yelovitch, S1
Barnard, EA; Järv, J; Sak, K1
Edvinsson, L; Erlinge, D; Hou, M; Malmsjö, M; Pendergast, W1
Boarder, MR; Dixon, CJ; Hall, JF; Luo, Y; White, PJ1
Eilers, J; Kraft, R; Michaelis, M; Nieswandt, B; Stegner, D1
Chee, XW; Gunasinghe, KKJ; Harper, MT; Rahman, T; Vadlamani, VMK1

Reviews

1 review(s) available for methylthio-adp and uridine diphosphate

ArticleYear
Purine and pyrimidine (P2) receptors as drug targets.
    Journal of medicinal chemistry, 2002, Sep-12, Volume: 45, Issue:19

    Topics: Adenosine Triphosphate; Animals; Drug Design; Humans; Ligands; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyrimidines; Receptors, Purinergic P2; Uridine Triphosphate

2002

Other Studies

7 other study(ies) available for methylthio-adp and uridine diphosphate

ArticleYear
Identification of hydrolytically stable and selective P2Y(1) receptor agonists.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Adenosine Triphosphatases; Animals; Biomimetics; Cell Line, Tumor; Drug Design; Gastric Juice; Humans; Hydrogen-Ion Concentration; Hydrolysis; Nucleotides; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2Y1; Substrate Specificity; Temperature

2009
Boranophosphate isoster controls P2Y-receptor subtype selectivity and metabolic stability of dinucleoside polyphosphate analogues.
    Journal of medicinal chemistry, 2012, Jan-12, Volume: 55, Issue:1

    Topics: Animals; Boranes; Calcium; Cell Line, Tumor; Dinucleoside Phosphates; Drug Stability; Humans; Hydrolysis; Models, Molecular; Molecular Conformation; Phosphoric Diester Hydrolases; Purinergic P2Y Receptor Agonists; Pyrophosphatases; Receptors, Purinergic P2Y; Stereoisomerism; Structure-Activity Relationship; Turkey

2012
Dual effect of nucleotides on P2Y receptors.
    IUBMB life, 2000, Volume: 50, Issue:2

    Topics: Adenosine Diphosphate; Binding Sites; Calcium; Cell Line; Dose-Response Relationship, Drug; Humans; Hydrolysis; Inhibitory Concentration 50; Ions; Kinetics; Ligands; Magnesium; Nucleotides; Phosphatidylinositols; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Thionucleotides; Tumor Cells, Cultured; Uridine Diphosphate

2000
The stable pyrimidines UDPbetaS and UTPgammaS discriminate between contractile cerebrovascular P2 receptors.
    European journal of pharmacology, 2003, Jan-05, Volume: 458, Issue:3

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Basilar Artery; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; In Vitro Techniques; Potassium; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2X; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thionucleotides; Uridine Diphosphate; Uridine Triphosphate; Vasoconstriction

2003
A role for Akt in epidermal growth factor-stimulated cell cycle progression in cultured hepatocytes: generation of a hyperproliferative window after adenoviral expression of constitutively active Akt.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 321, Issue:3

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenoviridae; Animals; Cell Cycle; Cell Proliferation; Cell Survival; Epidermal Growth Factor; Glycogen Phosphorylase; Hepatocytes; Inositol Phosphates; Insulin; Male; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; S Phase; Thionucleotides; TOR Serine-Threonine Kinases; Transfection; Uridine Diphosphate; Uridine Triphosphate

2007
STIM1, STIM2, and Orai1 regulate store-operated calcium entry and purinergic activation of microglia.
    Glia, 2015, Volume: 63, Issue:4

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Calcium Channels; Calcium Signaling; Cell Culture Techniques; Indoles; Lipopolysaccharides; Membrane Glycoproteins; Mice; Mice, Knockout; Mice, Transgenic; Microglia; ORAI1 Protein; Phagocytosis; Stromal Interaction Molecule 1; Stromal Interaction Molecule 2; Thionucleotides; Uridine Diphosphate

2015
Human soluble CD39 displays substrate inhibition in a substrate-specific manner.
    Scientific reports, 2023, 06-02, Volume: 13, Issue:1

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Apyrase; Humans; Uridine Diphosphate

2023