Page last updated: 2024-09-03

methylthio-adp and ticagrelor

methylthio-adp has been researched along with ticagrelor in 3 studies

Compound Research Comparison

Studies
(methylthio-adp)
Trials
(methylthio-adp)
Recent Studies (post-2010)
(methylthio-adp)
Studies
(ticagrelor)
Trials
(ticagrelor)
Recent Studies (post-2010) (ticagrelor)
1462432,4255942,246

Protein Interaction Comparison

ProteinTaxonomymethylthio-adp (IC50)ticagrelor (IC50)
P2Y purinoceptor 13Homo sapiens (human)1.398
P2Y purinoceptor 12Homo sapiens (human)1.1028

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's2 (66.67)2.80

Authors

AuthorsStudies
Chen, B; Danon, JJ; Kassiou, M; Ma, BB; Montgomery, AP1
Baqi, Y; Hoffmann, K; Lutz, DA; Müller, CE; Straßburger, J; von Kügelgen, I1
Amaradasa, K; Bancroft, S; Dimofte, T; Hindle, MS; Hutchinson, JL; Johnson, T; Keith, M; Khalil, J; Mundell, SJ; Naseem, K; Roberts, T1

Reviews

1 review(s) available for methylthio-adp and ticagrelor

ArticleYear
Strategies for targeting the P2Y
    Bioorganic & medicinal chemistry letters, 2022, 09-01, Volume: 71

    Topics: Central Nervous System; Ligands; Microglia; Platelet Aggregation; Receptors, Purinergic P2Y12; Signal Transduction

2022

Other Studies

2 other study(ies) available for methylthio-adp and ticagrelor

ArticleYear
Competitive mode and site of interaction of ticagrelor at the human platelet P2Y12 -receptor.
    Journal of thrombosis and haemostasis : JTH, 2014, Volume: 12, Issue:11

    Topics: Adenosine; Adenosine Diphosphate; Animals; Binding Sites; Binding, Competitive; CHO Cells; Colforsin; Cricetulus; Cyclic AMP; Dose-Response Relationship, Drug; Gene Expression Regulation; Genes, Reporter; Humans; Luciferases; Mutation; Platelet Aggregation Inhibitors; Protein Binding; Purinergic P2Y Receptor Agonists; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Response Elements; Thionucleotides; Ticagrelor; Transfection

2014
Ticagrelor inverse agonist activity at the P2Y
    British journal of pharmacology, 2024, Volume: 181, Issue:1

    Topics: Acute Coronary Syndrome; Adenosine; Adenosine Diphosphate; Blood Platelets; Diphosphates; Drug Inverse Agonism; Humans; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Ticagrelor

2024