methylthio-adp has been researched along with suramin in 11 studies
| Studies (methylthio-adp) | Trials (methylthio-adp) | Recent Studies (post-2010) (methylthio-adp) | Studies (suramin) | Trials (suramin) | Recent Studies (post-2010) (suramin) |
|---|---|---|---|---|---|
| 146 | 2 | 43 | 3,023 | 92 | 431 |
| Protein | Taxonomy | methylthio-adp (IC50) | suramin (IC50) |
|---|---|---|---|
| ATP-dependent 6-phosphofructokinase | Trypanosoma brucei brucei | 3 | |
| Tyrosine-protein phosphatase non-receptor type 1 | Homo sapiens (human) | 9.76 | |
| P2X purinoceptor 2 | Rattus norvegicus (Norway rat) | 4 | |
| DNA-dependent protein kinase catalytic subunit | Homo sapiens (human) | 1.7 | |
| DNA primase | Mycobacterium tuberculosis CDC1551 | 8.2 | |
| RmtA | Aspergillus nidulans | 5.9 | |
| Reverse transcriptase/RNaseH | Human immunodeficiency virus 1 | 9.4 | |
| NAD-dependent protein deacetylase sirtuin-2 | Homo sapiens (human) | 1.15 | |
| NAD-dependent protein deacetylase sirtuin-1 | Homo sapiens (human) | 1.5667 | |
| Protein arginine N-methyltransferase 1 | Homo sapiens (human) | 5.33 | |
| NAD-dependent protein deacylase sirtuin-5, mitochondrial | Homo sapiens (human) | 2.5 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (36.36) | 18.2507 |
| 2000's | 7 (63.64) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Harden, TK; Schachter, JB | 1 |
| Jacobson, KA; Jarvis, MF; Williams, M | 1 |
| Boyer, JL; Corbitt, J; Harden, TK; Jacobson, KA; Ji, XD; Kim, HS; Lacy, J; Ravi, G; Waldo, GL | 1 |
| Boeynaems, JM; Communi, D; Gonzalez, NS; Labouret, C; Le Poul, E; Marteau, F; Savi, P | 1 |
| Balcar, VJ; Bennett, MR; Killinger, S; Li, Y | 1 |
| Barnard, EA; Burnstock, G; King, BF; Simon, J; Webb, TE | 1 |
| Hourani, SM; Park, HS | 1 |
| Chambers, JK; Emson, PC; Moore, DJ; Murdock, PR | 1 |
| Allen, DG; Barden, JA; Huang, W; Jiang, L; Ju, YK | 1 |
| Burnstock, G; Cowen, T; Knight, GE; Wallace, A | 1 |
| Baqi, Y; Glänzel, M; Hoffmann, K; Morena, MS; Müller, CE; von Kügelgen, I | 1 |
1 review(s) available for methylthio-adp and suramin
| Article | Year |
|---|---|
Purine and pyrimidine (P2) receptors as drug targets.
Topics: Adenosine Triphosphate; Animals; Drug Design; Humans; Ligands; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyrimidines; Receptors, Purinergic P2; Uridine Triphosphate | 2002 |
10 other study(ies) available for methylthio-adp and suramin
| Article | Year |
|---|---|
An examination of deoxyadenosine 5'(alpha-thio)triphosphate as a ligand to define P2Y receptors and its selectivity as a low potency partial agonist of the P2Y1 receptor.
Topics: Adenosine Triphosphate; Dose-Response Relationship, Drug; Humans; Radioligand Assay; Receptors, Purinergic P2; Receptors, Purinergic P2Y1 | 1997 |
Quantitation of the P2Y(1) receptor with a high affinity radiolabeled antagonist.
Topics: Adenosine Diphosphate; Animals; Cells, Cultured; Female; Humans; Insecta; Purinergic P2 Receptor Antagonists; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Tritium | 2002 |
Pharmacological characterization of the human P2Y13 receptor.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cell Membrane; CHO Cells; Cricetinae; Cyclic AMP; Female; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Inositol Phosphates; Kinetics; Receptors, Purinergic P2; Thionucleotides | 2003 |
Autoradiography of P2x ATP receptors in the rat brain.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Autoradiography; Binding, Competitive; Brain; Brain Stem; Cerebellum; Cerebral Cortex; Dilazep; Female; Hippocampus; Ligands; Male; Ouabain; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Structure-Activity Relationship; Suramin; Thalamus; Thionucleotides | 1995 |
Characterisation of a recombinant P2Y purinoceptor.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Animals; Brain; Cell Line; Electrophysiology; Inositol Phosphates; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Recombinant Proteins; Suramin; Thionucleotides; Triazines; Uridine Triphosphate; Xenopus | 1995 |
Differential effects of adenine nucleotide analogues on shape change and aggregation induced by adnosine 5-diphosphate (ADP) in human platelets.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Blood Platelets; Cell Size; Dose-Response Relationship, Drug; Humans; Platelet Aggregation; Suramin; Thionucleotides; Trypanocidal Agents; Uridine Triphosphate | 1999 |
Human Ntera-2/D1 neuronal progenitor cells endogenously express a functional P2Y1 receptor.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Antineoplastic Agents; Blotting, Western; Calcium; Cell Membrane; Cells, Cultured; Cyclic AMP; Fluorescence; GTP-Binding Protein alpha Subunits, Gq-G11; Heterotrimeric GTP-Binding Proteins; Humans; Membrane Proteins; Mitogen-Activated Protein Kinases; Neurons; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Receptors, Purinergic P2Y2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stem Cells; Suramin; Thionucleotides; Uridine Triphosphate | 2002 |
ATP modulates intracellular Ca2+ and firing rate through a P2Y1 purinoceptor in cane toad pacemaker cells.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Biological Clocks; Blotting, Western; Bufo marinus; Calcium; Electrophysiology; Heart; Immunohistochemistry; Intracellular Membranes; Myocardium; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Sarcoplasmic Reticulum; Suramin; Thionucleotides; Type C Phospholipases | 2003 |
Changes in purinergic signalling in developing and ageing rat tail artery: importance for temperature control.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Aging; Animals; Arteries; Dose-Response Relationship, Drug; Electric Stimulation; Immunohistochemistry; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Norepinephrine; Prazosin; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Regional Blood Flow; Signal Transduction; Suramin; Tail; Thionucleotides; Uridine Triphosphate | 2006 |
Interaction of new, very potent non-nucleotide antagonists with Arg256 of the human platelet P2Y12 receptor.
Topics: Adenosine Diphosphate; Animals; Arginine; Binding, Competitive; CHO Cells; Cloning, Molecular; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Cyclic AMP Response Element Modulator; Humans; Isomerism; Luciferases; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Sulfonic Acids; Suramin; Thionucleotides; Triazines | 2009 |