methylthio-adp has been researched along with clopidogrel in 13 studies
| Studies (methylthio-adp) | Trials (methylthio-adp) | Recent Studies (post-2010) (methylthio-adp) | Studies (clopidogrel) | Trials (clopidogrel) | Recent Studies (post-2010) (clopidogrel) |
|---|---|---|---|---|---|
| 146 | 2 | 43 | 10,221 | 1,918 | 5,951 |
| Protein | Taxonomy | methylthio-adp (IC50) | clopidogrel (IC50) |
|---|---|---|---|
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.562 | |
| P2Y purinoceptor 12 | Homo sapiens (human) | 2.4 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (38.46) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 4 (30.77) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, B; Danon, JJ; Kassiou, M; Ma, BB; Montgomery, AP | 1 |
| Colman, RF; Colman, RW; Freedman, MD; Grana, G; Hu, CJ; Mills, DC; Minniti, C; Puri, R | 1 |
| Aït-Chek, L; Bernat, A; Dumas, A; Herbert, JM; Savi, P | 1 |
| Herbert, JM; Laplace, MC; Maffrand, JP; Savi, P | 1 |
| Cassel, D; Cattaneo, M; Cazenave, JP; Chevalier, J; Gachet, C; Hechler, B; Lecchi, A; Mannucci, PM; Ohlmann, P | 1 |
| Artçanuthurry, V; Bornia, J; Grelac, F; Herbert, JM; Levy-Toledano, S; Maclouf, J; Savi, P | 1 |
| Asai, F; Inoue, T; Koike, H; Ogawa, T; Sugidachi, A | 1 |
| Bryckaert, M; Contreres, JO; Dupuy, E; Habib, A; Herbert, JM; Job, B; Levy-Toledano, S; Rosa, JP; Savi, P; Simoneau, G | 1 |
| Crain, EJ; Hua, J; Rehfuss, R; Schumacher, WA; Watson, CA; Wong, PC | 1 |
| Carneiro, FS; Giachini, FR; Inscho, EW; Lima, VV; Osmond, DA; Tostes, RC; Webb, RC; Zhang, S | 1 |
| Bal Dit Sollier, C; Berge, N; Boval, B; Drouet, L; Dubar, M | 1 |
| Brasseur, D; Bremond, N; Delesque Touchard, N; Hurbin, F; Lavisse, M; Rouchon, MC; Roy, S; Savi, P; Schofield, J; Sultan, E; Tuffal, G | 1 |
| Giachini, FR; Inscho, EW; Leite, R; Lima, VV; Osmond, DA; Tostes, RC; Webb, RC | 1 |
1 review(s) available for methylthio-adp and clopidogrel
| Article | Year |
|---|---|
Strategies for targeting the P2Y
Topics: Central Nervous System; Ligands; Microglia; Platelet Aggregation; Receptors, Purinergic P2Y12; Signal Transduction | 2022 |
2 trial(s) available for methylthio-adp and clopidogrel
| Article | Year |
|---|---|
Clopidogrel inhibits the binding of ADP analogues to the receptor mediating inhibition of platelet adenylate cyclase.
Topics: Adenosine; Adenosine Diphosphate; Adenylyl Cyclase Inhibitors; Adult; Binding Sites; Blood Platelets; Clopidogrel; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Receptors, Purinergic; Thionucleotides; Thrombin; Ticlopidine | 1992 |
Differential sensitivity and kinetics of response of different ex vivo tests monitoring functional variability of platelet response to clopidogrel.
Topics: Adenosine Diphosphate; Adult; Blood Platelets; Cell Adhesion Molecules; Clopidogrel; Double-Blind Method; Flow Cytometry; Humans; Kinetics; Male; Microfilament Proteins; Nephelometry and Turbidimetry; P-Selectin; Phosphoproteins; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Receptors, Purinergic P2Y12; Sensitivity and Specificity; Thionucleotides; Thrombelastography; Ticlopidine; Young Adult | 2010 |
10 other study(ies) available for methylthio-adp and clopidogrel
| Article | Year |
|---|---|
Effect of aspirin and clopidogrel on platelet-dependent tissue factor expression in endothelial cells.
Topics: Adenosine Diphosphate; Animals; Aorta; Aspirin; Blood Platelets; Cattle; Clopidogrel; Endothelium, Vascular; Female; Ligation; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Thionucleotides; Thrombin; Thromboplastin; Thrombosis; Ticlopidine; Vena Cava, Inferior | 1994 |
Binding of [3H]-2-methylthio ADP to rat platelets--effect of clopidogrel and ticlopidine.
Topics: Adenosine Diphosphate; Adenylyl Cyclases; Animals; Binding Sites; Blood Platelets; Clopidogrel; Female; In Vitro Techniques; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Thionucleotides; Ticlopidine | 1994 |
Purinoceptors on blood platelets: further pharmacological and clinical evidence to suggest the presence of two ADP receptors.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Clopidogrel; Female; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Receptors, Purinergic P2; Thionucleotides; Ticlopidine | 1995 |
Effect of clopidogrel treatment on ADP-induced phosphorylations in rat platelets.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Clopidogrel; Female; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Thionucleotides; Ticlopidine | 1997 |
The in vivo pharmacological profile of CS-747, a novel antiplatelet agent with platelet ADP receptor antagonist properties.
Topics: Adenosine Diphosphate; Administration, Oral; Animals; Arteriovenous Shunt, Surgical; Binding, Competitive; Bleeding Time; Blood Platelets; Clopidogrel; Collagen; Cyclic AMP; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrinolytic Agents; Male; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Thionucleotides; Thiophenes; Thrombin; Thrombosis; Ticlopidine; Time Factors; Tritium | 2000 |
Effect of clopidogrel administration to healthy volunteers on platelet phosphorylation events triggered by ADP.
Topics: Adenosine Diphosphate; Adolescent; Adult; Benzylamines; Blood Platelets; Clopidogrel; Electrophoresis, Polyacrylamide Gel; Humans; Male; Membrane Proteins; Phosphorylation; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Serine; Signal Transduction; Thiazoles; Thionucleotides; Threonine; Ticlopidine; Tyrosine | 2003 |
Clopidogrel versus prasugrel in rabbits. Effects on thrombosis, haemostasis, platelet function and response variability.
Topics: Adenosine Diphosphate; Administration, Oral; Animals; Binding, Competitive; Bleeding Time; Clopidogrel; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrinolytic Agents; Hemorrhage; Hemostasis; Male; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prasugrel Hydrochloride; Purinergic P2 Receptor Antagonists; Rabbits; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Thionucleotides; Thiophenes; Thrombosis; Ticlopidine | 2009 |
Clopidogrel, independent of the vascular P2Y12 receptor, improves arterial function in small mesenteric arteries from AngII-hypertensive rats.
Topics: Acetylcholine; Adenosine Diphosphate; Angiotensin II; Animals; Blotting, Western; Clopidogrel; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Hypertension; In Vitro Techniques; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Purinergic P2Y Receptor Antagonists; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Thionucleotides; Ticlopidine; Vasodilation; Vasodilator Agents | 2010 |
An improved method for specific and quantitative determination of the clopidogrel active metabolite isomers in human plasma.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; CHO Cells; Chromatography, High Pressure Liquid; Clopidogrel; Cricetinae; Cricetulus; Humans; Mass Spectrometry; Phosphorus Isotopes; Plasma; Product Surveillance, Postmarketing; Protein Binding; Receptors, Purinergic P2Y12; Sensitivity and Specificity; Stereoisomerism; Thionucleotides; Ticlopidine; Transgenes | 2011 |
Anti-platelet therapy with clopidogrel prevents endothelial dysfunction and vascular remodeling in aortas from hypertensive rats.
Topics: Adenosine Diphosphate; Animals; Aorta; Blood Pressure; Clopidogrel; Disease Models, Animal; Endothelium, Vascular; Gene Expression; Hypertension; Male; Platelet Aggregation Inhibitors; Purinergic P2Y Receptor Antagonists; Rats; Receptors, Purinergic P2Y; Thionucleotides; Ticlopidine; Vascular Remodeling; Vasoconstriction; Vasodilation | 2014 |