methylthio-adp has been researched along with cangrelor in 8 studies
| Studies (methylthio-adp) | Trials (methylthio-adp) | Recent Studies (post-2010) (methylthio-adp) | Studies (cangrelor) | Trials (cangrelor) | Recent Studies (post-2010) (cangrelor) |
|---|---|---|---|---|---|
| 146 | 2 | 43 | 418 | 54 | 286 |
| Protein | Taxonomy | methylthio-adp (IC50) | cangrelor (IC50) |
|---|---|---|---|
| Ornithine decarboxylase | Rattus norvegicus (Norway rat) | 0.0004 | |
| P2Y purinoceptor 12 | Homo sapiens (human) | 0.0043 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (75.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Furuichi, K; Kamohara, M; Matsumoto, M; Matsumoto, S; Matsushime, H; Ohishi, T; Saito, T; Soga, T; Takasaki, J | 1 |
| Jacobson, KA; Jarvis, MF; Williams, M | 1 |
| Boeynaems, JM; Communi, D; Gonzalez, NS; Labouret, C; Le Poul, E; Marteau, F; Savi, P | 1 |
| Chen, B; Danon, JJ; Kassiou, M; Ma, BB; Montgomery, AP | 1 |
| Slegers, H; Van Kolen, K | 1 |
| Gerevich, Z; Illes, P; Müller, C | 1 |
| Di Pasquale, F; Hoffmann, K; Sixel, U; von Kügelgen, I | 1 |
| Cinalli, AR; Fernández, V; Guarracino, JF; Losavio, AS; Roquel, LI | 1 |
2 review(s) available for methylthio-adp and cangrelor
| Article | Year |
|---|---|
Purine and pyrimidine (P2) receptors as drug targets.
Topics: Adenosine Triphosphate; Animals; Drug Design; Humans; Ligands; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyrimidines; Receptors, Purinergic P2; Uridine Triphosphate | 2002 |
Strategies for targeting the P2Y
Topics: Central Nervous System; Ligands; Microglia; Platelet Aggregation; Receptors, Purinergic P2Y12; Signal Transduction | 2022 |
6 other study(ies) available for methylthio-adp and cangrelor
| Article | Year |
|---|---|
Molecular cloning of the platelet P2T(AC) ADP receptor: pharmacological comparison with another ADP receptor, the P2Y(1) receptor.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Binding, Competitive; Cells, Cultured; Cloning, Molecular; Humans; Membrane Proteins; Molecular Sequence Data; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Sequence Homology, Amino Acid; Thionucleotides; Tissue Distribution; Tritium | 2001 |
Pharmacological characterization of the human P2Y13 receptor.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cell Membrane; CHO Cells; Cricetinae; Cyclic AMP; Female; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Inositol Phosphates; Kinetics; Receptors, Purinergic P2; Thionucleotides | 2003 |
P2Y12 receptor stimulation inhibits beta-adrenergic receptor-induced differentiation by reversing the cyclic AMP-dependent inhibition of protein kinase B.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenylyl Cyclase Inhibitors; Adrenergic beta-Agonists; Animals; Cell Differentiation; Cell Division; Cell Line, Tumor; Cyclic AMP; Enzyme Inhibitors; Glial Fibrillary Acidic Protein; Glioma; GTP-Binding Protein alpha Subunits, Gi-Go; Membrane Proteins; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rats; Receptors, Adrenergic, beta; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Thionucleotides | 2004 |
Metabotropic P2Y1 receptors inhibit P2X3 receptor-channels in rat dorsal root ganglion neurons.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Animals, Newborn; Cells, Cultured; Dose-Response Relationship, Drug; Ganglia, Spinal; Guanosine 5'-O-(3-Thiotriphosphate); Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Pertussis Toxin; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2X3; Receptors, Purinergic P2Y1; Thionucleotides | 2005 |
Involvement of basic amino acid residues in transmembrane regions 6 and 7 in agonist and antagonist recognition of the human platelet P2Y(12)-receptor.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Amino Acid Motifs; Animals; Binding Sites; Cell Line, Tumor; CHO Cells; Cricetinae; Cricetulus; Humans; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Thionucleotides | 2008 |
P2Y13 receptors mediate presynaptic inhibition of acetylcholine release induced by adenine nucleotides at the mouse neuromuscular junction.
Topics: Acetylcholine; Adenosine Diphosphate; Adenosine Monophosphate; Animals; Female; Male; Mice; Miniature Postsynaptic Potentials; Neuromuscular Junction; Purinergic P2 Receptor Agonists; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y12; Thionucleotides | 2016 |