methylthio-adp has been researched along with 2-methylthio-atp in 20 studies
| Studies (methylthio-adp) | Trials (methylthio-adp) | Recent Studies (post-2010) (methylthio-adp) | Studies (2-methylthio-atp) | Trials (2-methylthio-atp) | Recent Studies (post-2010) (2-methylthio-atp) |
|---|---|---|---|---|---|
| 146 | 2 | 43 | 265 | 0 | 16 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (40.00) | 18.2507 |
| 2000's | 8 (40.00) | 29.6817 |
| 2010's | 4 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boyer, JL; Brizzolara, AL; Burnstock, G; Fischer, B; Harden, TK; Hoyle, CH; Jacobson, KA; Knight, GE; Ziganshin, AU; Zimmet, J | 1 |
| Harden, TK; Schachter, JB | 1 |
| Boyer, JL; Harden, TK; Jacobson, KA; Kim, HS; Lee, K; Maddileti, S; Ravi, RG; Servos, J; Zimmermann, H | 1 |
| Jacobson, KA; Jarvis, MF; Williams, M | 1 |
| Boyer, JL; Corbitt, J; Harden, TK; Jacobson, KA; Ji, XD; Kim, HS; Lacy, J; Ravi, G; Waldo, GL | 1 |
| Boeynaems, JM; Communi, D; Gonzalez, NS; Labouret, C; Le Poul, E; Marteau, F; Savi, P | 1 |
| Baqi, Y; Malik, EM; Müller, CE; Namasivayam, V; Neumann, A; Rafehi, M; Wiese, M | 1 |
| Lee, SY; Müller, CE | 1 |
| Balcar, VJ; Bennett, MR; Killinger, S; Li, Y | 1 |
| Barnard, EA; Burnstock, G; King, BF; Simon, J; Webb, TE | 1 |
| Harden, TK; Nicholas, RA; Schachter, JB; Sromek, SM | 1 |
| Duchêne, AD; Takeda, K | 1 |
| Boyer, JL; Harden, TK; Nicholas, RA; Palmer, RK; Schachter, JB | 1 |
| Ias'ko, MV; Skoblov, IuS; Skoblov, MIu | 1 |
| Fam, SR; Gallagher, CJ; Salter, MW | 1 |
| Dixon, CJ | 1 |
| Chambers, JK; Emson, PC; Moore, DJ; Murdock, PR | 1 |
| Fraga, S; Gonçalves, J; Queiroz, G; Quintas, C | 1 |
| Boehm, S; Chandaka, GK; Drobny, H; Salzer, I; Schicker, KW | 1 |
| Cherezov, V; Gao, ZG; Han, GW; Jacobson, KA; Jiang, H; Katritch, V; Li, T; Ma, L; Müller, CE; Paoletta, S; Stevens, RC; Wu, B; Yang, H; Zhang, D; Zhang, J; Zhang, K; Zhang, W; Zhao, Q | 1 |
2 review(s) available for methylthio-adp and 2-methylthio-atp
| Article | Year |
|---|---|
Purine and pyrimidine (P2) receptors as drug targets.
Topics: Adenosine Triphosphate; Animals; Drug Design; Humans; Ligands; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyrimidines; Receptors, Purinergic P2; Uridine Triphosphate | 2002 |
Nucleotide pyrophosphatase/phosphodiesterase 1 (NPP1) and its inhibitors.
Topics: | 2017 |
18 other study(ies) available for methylthio-adp and 2-methylthio-atp
| Article | Year |
|---|---|
Identification of potent, selective P2Y-purinoceptor agonists: structure-activity relationships for 2-thioether derivatives of adenosine 5'-triphosphate.
Topics: Adenine Nucleotides; Animals; Aorta; Colon; Enzyme Activation; Erythrocyte Membrane; Guinea Pigs; Male; Mesenteric Arteries; Muscle Relaxation; Muscle, Smooth; Rabbits; Receptors, Purinergic P2; Structure-Activity Relationship; Sulfides; Turkeys; Type C Phospholipases; Vas Deferens | 1993 |
An examination of deoxyadenosine 5'(alpha-thio)triphosphate as a ligand to define P2Y receptors and its selectivity as a low potency partial agonist of the P2Y1 receptor.
Topics: Adenosine Triphosphate; Dose-Response Relationship, Drug; Humans; Radioligand Assay; Receptors, Purinergic P2; Receptors, Purinergic P2Y1 | 1997 |
Adenine nucleotide analogues locked in a Northern methanocarba conformation: enhanced stability and potency as P2Y(1) receptor agonists.
Topics: Adenine Nucleotides; Adenosine Triphosphatases; Animals; Antigens, CD; Apyrase; CHO Cells; Cricetinae; Erythrocyte Membrane; Humans; Hydrolysis; In Vitro Techniques; Inositol Phosphates; Molecular Conformation; Purinergic P2 Receptor Agonists; Rats; Receptors, Purinergic P2Y1; Recombinant Proteins; Structure-Activity Relationship; Transfection; Tumor Cells, Cultured; Turkey; Type C Phospholipases | 2002 |
Quantitation of the P2Y(1) receptor with a high affinity radiolabeled antagonist.
Topics: Adenosine Diphosphate; Animals; Cells, Cultured; Female; Humans; Insecta; Purinergic P2 Receptor Antagonists; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Tritium | 2002 |
Pharmacological characterization of the human P2Y13 receptor.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cell Membrane; CHO Cells; Cricetinae; Cyclic AMP; Female; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Inositol Phosphates; Kinetics; Receptors, Purinergic P2; Thionucleotides | 2003 |
Molecular Recognition of Agonists and Antagonists by the Nucleotide-Activated G Protein-Coupled P2Y
Topics: Cell Line, Tumor; Crystallography, X-Ray; Humans; Models, Molecular; Mutagenesis, Site-Directed; Purinergic P2Y Receptor Agonists; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y2; Sequence Homology, Amino Acid; Spectrum Analysis | 2017 |
Autoradiography of P2x ATP receptors in the rat brain.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Autoradiography; Binding, Competitive; Brain; Brain Stem; Cerebellum; Cerebral Cortex; Dilazep; Female; Hippocampus; Ligands; Male; Ouabain; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Structure-Activity Relationship; Suramin; Thalamus; Thionucleotides | 1995 |
Characterisation of a recombinant P2Y purinoceptor.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Animals; Brain; Cell Line; Electrophysiology; Inositol Phosphates; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Recombinant Proteins; Suramin; Thionucleotides; Triazines; Uridine Triphosphate; Xenopus | 1995 |
HEK293 human embryonic kidney cells endogenously express the P2Y1 and P2Y2 receptors.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cell Line; Cricetinae; Humans; In Vitro Techniques; Inositol Phosphates; Kidney; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y2; Stimulation, Chemical; Thionucleotides | 1997 |
P2Y- and P2U-mediated increases in internal calcium in single bovine aortic endothelial cells in primary culture.
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Calcium; Cattle; Cells, Cultured; Ion Transport; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Thionucleotides; Uridine Triphosphate | 1997 |
Agonist action of adenosine triphosphates at the human P2Y1 receptor.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Calcium; Cell Line; Dose-Response Relationship, Drug; Humans; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2Y1; Thionucleotides; Tumor Cells, Cultured | 1998 |
[Preparation of 32P-labelled 2-methylthioadenosine di- and triphosphates].
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Chromatography, High Pressure Liquid; Phosphorus Radioisotopes; Phosphorylation; Radiochemistry; Thionucleotides | 1999 |
P2Y(1) purinoceptor-mediated Ca(2+) signaling and Ca(2+) wave propagation in dorsal spinal cord astrocytes.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Astrocytes; Calcium; Calcium Signaling; Cells, Cultured; Embryo, Mammalian; Female; Posterior Horn Cells; Pregnancy; Rats; Rats, Wistar; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; RNA, Messenger; Thionucleotides; Uridine Triphosphate | 2000 |
Evidence that 2-methylthioATP and 2-methylthioADP are both agonists at the rat hepatocyte P2Y(1) receptor.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium Signaling; Liver; Male; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P2Y1; Thionucleotides; Uridine Triphosphate | 2000 |
Human Ntera-2/D1 neuronal progenitor cells endogenously express a functional P2Y1 receptor.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Antineoplastic Agents; Blotting, Western; Calcium; Cell Membrane; Cells, Cultured; Cyclic AMP; Fluorescence; GTP-Binding Protein alpha Subunits, Gq-G11; Heterotrimeric GTP-Binding Proteins; Humans; Membrane Proteins; Mitogen-Activated Protein Kinases; Neurons; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Receptors, Purinergic P2Y2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stem Cells; Suramin; Thionucleotides; Uridine Triphosphate | 2002 |
The P2Y(1) and P2Y(12) receptors mediate autoinhibition of transmitter release in sympathetic innervated tissues.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antidepressive Agents, Tricyclic; Arteries; Blotting, Western; Desipramine; Epididymis; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Neurotransmitter Agents; Norepinephrine; Rats; Rats, Wistar; Receptor Cross-Talk; Receptor, Adenosine A1; Receptors, Adrenergic, alpha-2; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y12; Signal Transduction; Sympathetic Nervous System; Thionucleotides; Vas Deferens | 2009 |
Facilitation of transmitter release from rat sympathetic neurons via presynaptic P2Y(1) receptors.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Animals, Newborn; Cell Culture Techniques; Cloning, Molecular; Electric Stimulation; Green Fluorescent Proteins; KCNQ Potassium Channels; Maximum Tolerated Dose; Neurons; Neurotransmitter Agents; Norepinephrine; Patch-Clamp Techniques; PC12 Cells; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Receptors, Presynaptic; Receptors, Purinergic P2Y1; Superior Cervical Ganglion; Synaptic Transmission; Thionucleotides | 2011 |
Agonist-bound structure of the human P2Y12 receptor.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Binding Sites; Crystallography, X-Ray; Humans; Ligands; Models, Molecular; Niacin; Protein Conformation; Purinergic P2Y Receptor Agonists; Purinergic P2Y Receptor Antagonists; Receptors, Purinergic P2Y12; Substrate Specificity; Sulfonamides; Thionucleotides | 2014 |