methyltestosterone and flutamide

methyltestosterone has been researched along with flutamide in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19903 (17.65)18.7374
1990's0 (0.00)18.2507
2000's8 (47.06)29.6817
2010's5 (29.41)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brugmans, M; DaVanzo, JP; Greenslade, FC; Heilman, RD1
Shaw, CJ; Snyder, BW; Wagner, MM; Winneker, RC1
Fukata, J; Martin, JB1
Ashby, J; Lefevre, PA; Owens, W1
Clark, AS; Kelton, MC; Whitney, AC1
Brown, KM; Goering, PL; Papaconstantinou, AD; Umbreit, TH1
Kim, YC; Lee, BJ; Nam, SY; Yu, WJ; Yun, YW1
Ahn, B; Do, JC; Hong, JT; Kim, YC; Lee, BJ; Lee, YS; Nam, SY; Yu, WJ; Yun, YW1
Choi, SH; Kim, YU; Kwon, HC; Kwon, JY; Son, SO1
Hurst, MR; James, JD; Katsiadaki, I; Morris, S; Scott, AP; Squires, C1
Bottero, S; Cevasco, A; Kloas, W; Mandich, A; Massari, A; Pedemonte, F; Urbatzka, R1
Denslow, N; Hirakawa, I; Iguchi, T; Inohaya, K; Miyagawa, S; Ogino, Y; Sumiya, E; Tatarazako, N; Yamada, G1
Golan, M; Levavi-Sivan, B1
Honda, H; Ito, Y; Kawamoto, T; Morita, O1
Lawless, J; Wang, S; Zheng, Z1

Reviews

1 review(s) available for methyltestosterone and flutamide

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

16 other study(ies) available for methyltestosterone and flutamide

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Resistance of androgen-mediated aggressive behavior in mice to flutamide, an antiandrogen.
    Psychopharmacology, 1976, May-05, Volume: 47, Issue:1

    Topics: Aggression; Anilides; Animals; Castration; Flutamide; Humans; Male; Methyltestosterone; Mice; Organ Size; Prostate; Seminal Vesicles; Social Isolation

1976
Antiandrogens do not reverse androgen-induced inhibition of sex hormone-binding globulin levels in adult female rhesus monkeys.
    Endocrinology, 1989, Volume: 125, Issue:2

    Topics: Androgen Antagonists; Androgens; Animals; Biomarkers; Cyproterone; Cyproterone Acetate; Female; Flutamide; Macaca; Macaca mulatta; Methyltestosterone; Ovariectomy; Pregnanes; Pyrazoles; Sex Hormone-Binding Globulin

1989
Influence of sex steroid hormones on rat growth hormone-releasing factor and somatostatin in dispersed pituitary cells.
    Endocrinology, 1986, Volume: 119, Issue:5

    Topics: Animals; Dexamethasone; Dihydrotestosterone; Estradiol; Female; Flutamide; Gonadal Steroid Hormones; Growth Hormone-Releasing Hormone; Methyltestosterone; Norethindrone; Pituitary Gland; Progesterone; Rats; Rats, Inbred Strains; Somatostatin; Testosterone

1986
Concept evaluation: androgen-stimulated immature intact male rats as an assay for antiandrogens.
    Regulatory toxicology and pharmacology : RTP, 2002, Volume: 35, Issue:2 Pt 1

    Topics: Administration, Oral; Androgen Antagonists; Androgens; Animals; Clinical Protocols; Dichlorodiphenyl Dichloroethylene; Dose-Response Relationship, Drug; Drug Therapy, Combination; Flutamide; Genitalia, Male; Male; Methyltestosterone; Rats; Rats, Inbred Strains; Sexual Maturation

2002
Chronic administration of anabolic steroids disrupts pubertal onset and estrous cyclicity in rats.
    Biology of reproduction, 2003, Volume: 68, Issue:2

    Topics: Anabolic Agents; Androgen Antagonists; Androgen Receptor Antagonists; Animals; Body Weight; Drug Administration Schedule; Drug Combinations; Estrus; Female; Flutamide; Methandrostenolone; Methyltestosterone; Pregnancy; Rats; Rats, Long-Evans; Receptors, Androgen; Sexual Maturation; Stanozolol; Time Factors; Vagina

2003
Effects of 17 alpha-methyltestosterone on uterine morphology and heat shock protein expression are mediated through estrogen and androgen receptors.
    The Journal of steroid biochemistry and molecular biology, 2002, Volume: 82, Issue:4-5

    Topics: Androgen Antagonists; Animals; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Estradiol; Estrogen Antagonists; Female; Flutamide; Fulvestrant; Heat-Shock Proteins; HSP70 Heat-Shock Proteins; HSP72 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Immunoenzyme Techniques; Membrane Proteins; Methyltestosterone; Mice; Organ Size; Ovariectomy; Receptors, Androgen; Receptors, Estrogen; Testosterone Congeners; Uterus

2002
Effects of tributyltin chloride on the reproductive system in pubertal male rats.
    Journal of veterinary science, 2003, Volume: 4, Issue:1

    Topics: Animals; Body Weight; Epididymis; Flutamide; Genitalia, Male; Male; Methyltestosterone; Organ Size; Prostate; Rats; Rats, Sprague-Dawley; Seminal Vesicles; Sexual Maturation; Testis; Trialkyltin Compounds

2003
Reproductive disorders in pubertal and adult phase of the male rats exposed to vinclozolin during puberty.
    The Journal of veterinary medical science, 2004, Volume: 66, Issue:7

    Topics: Administration, Oral; Androgen Antagonists; Animals; Flutamide; Fungicides, Industrial; Male; Methyltestosterone; Oxazoles; Rats; Rats, Sprague-Dawley; Seminal Vesicles; Sperm Count; Sperm Motility; Spermatozoa; Testis; Testosterone

2004
Androgen action on hepatic vitellogenin synthesis in the eel, Anguilla japonica is suppressed by an androgen receptor antagonist.
    The Journal of steroid biochemistry and molecular biology, 2005, Volume: 96, Issue:2

    Topics: Androgen Receptor Antagonists; Anguilla; Animals; Estradiol; Female; Flutamide; Growth Hormone; Hepatocytes; Liver; Male; Methyltestosterone; Tamoxifen; Vitellogenins

2005
Use of the three-spined stickleback (Gasterosteus aculeatus) as a sensitive in vivo test for detection of environmental antiandrogens.
    Environmental health perspectives, 2006, Volume: 114 Suppl 1

    Topics: Angiogenesis Inhibitors; Animals; Dihydrotestosterone; Environmental Exposure; Ethinyl Estradiol; Female; Fish Proteins; Flutamide; Kidney; Male; Methyltestosterone; Models, Animal; Osmolar Concentration; Seasons; Smegmamorpha

2006
Endocrine disrupting chemicals (EDC) with (anti)estrogenic and (anti)androgenic modes of action affecting reproductive biology of Xenopus laevis: II. Effects on gonad histomorphology.
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2008, Volume: 147, Issue:2

    Topics: Animals; Endocrine Disruptors; Environmental Monitoring; Ethinyl Estradiol; Female; Flutamide; Male; Methyltestosterone; Ovary; Tamoxifen; Testis; Xenopus laevis

2008
Bmp7 and Lef1 are the downstream effectors of androgen signaling in androgen-induced sex characteristics development in medaka.
    Endocrinology, 2014, Volume: 155, Issue:2

    Topics: Androgen Antagonists; Androgens; Animals; Bone Morphogenetic Protein 7; Female; Flutamide; Lymphoid Enhancer-Binding Factor 1; Male; Methyltestosterone; Oryzias; Receptors, Androgen; Sex Differentiation; Signal Transduction

2014
Artificial masculinization in tilapia involves androgen receptor activation.
    General and comparative endocrinology, 2014, Oct-01, Volume: 207

    Topics: Androgen Antagonists; Androgens; Animals; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Dihydrotestosterone; Fadrozole; Female; Flutamide; Gonads; Humans; Male; Methyltestosterone; Receptors, Androgen; Sex Differentiation; Tilapia

2014
Mechanism-based risk assessment strategy for drug-induced cholestasis using the transcriptional benchmark dose derived by toxicogenomics.
    The Journal of toxicological sciences, 2017, Volume: 42, Issue:4

    Topics: Administration, Oral; Animals; Chlorpromazine; Cholestasis; Cholesterol; Cyclosporine; Diclofenac; Dose-Response Relationship, Drug; Flutamide; Gene Expression; Humans; Imipramine; Inflammation; Ketoconazole; Liver; Methyltestosterone; Oxidative Stress; Rats; Risk Assessment; Sulindac; Tamoxifen; Toxicogenetics

2017
Prenatal low-dose methyltestosterone, but not dihydrotestosterone, treatment induces penile formation in female mice and guinea pigsā€ .
    Biology of reproduction, 2020, 05-26, Volume: 102, Issue:6

    Topics: Active Transport, Cell Nucleus; Androgen Antagonists; Animals; Animals, Newborn; Cell Death; Cell Proliferation; Dihydrotestosterone; Drug Therapy, Combination; Female; Flutamide; Genitalia, Female; Guinea Pigs; Male; Methyltestosterone; Mice; Penis; Pregnancy; Receptors, Androgen; Sex Determination Analysis; Testosterone

2020