methylprednisolone hemisuccinate has been researched along with methylprednisolone in 190 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 150 (78.95) | 18.7374 |
| 1990's | 25 (13.16) | 18.2507 |
| 2000's | 8 (4.21) | 29.6817 |
| 2010's | 2 (1.05) | 24.3611 |
| 2020's | 5 (2.63) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Archer, LT; Beller, BK; Flournoy, DJ; Hinshaw, LB; Phillips, RW; White, GL | 1 |
| Varesi, M | 1 |
| Geelhoed, GW | 1 |
| Machiedo, GW; Rush, BF | 1 |
| Joyce, LD; Lillehei, RC; Mauer, HG; Smith, JM | 1 |
| Machiedo, GW; Rush, BF; Slotman, GJ; Tesoriero, R | 1 |
| Archer, LT; Elmore, OF; Hinshaw, LB; White, GL | 1 |
| Baylis, EM; Chakraborty, J; Dumasia, MC; Lawson, GJ | 1 |
| Camara, DS; Dunn, TE; Jusko, WJ; Ludwig, EA; Slaughter, RL | 1 |
| Jusko, WJ; Kong, AN | 1 |
| Cabanillas, F | 1 |
| Esclamado, RM; Larrabee, WF; Zel, GE | 1 |
| Hammerschmidt, DE; Jacob, HS; Knabe, AC; Lamche, HR; Silberstein, PT; Thomas, DD | 1 |
| Beam, TR; Jungbluth, GL; Jusko, WJ; Kong, AN; Pasko, MT | 1 |
| Argenta, LC; Kaiser, DG; Morykwas, MJ; Oneal, RM | 1 |
| Byrick, RJ; Kay, JC; Mullen, JB; Wigglesworth, D; Wong, PY | 1 |
| Farber, BF; Kaplan, MH; Schiff, MJ | 1 |
| Aasen, AO; Lium, B; Pillgram-Larsen, J; Ruud, TE; Røise, O; Stadaas, JO | 1 |
| Jynge, P; Sellevold, OF | 2 |
| Carroll, DJ; Catz, I; Warren, KG | 1 |
| Giongo, F; Lucchi, R; Popiela, T | 1 |
| Alvinerie, M; Galtier, P; Houin, G; Toutain, PL; Tufenkji, AE | 1 |
| Dyste, GN; Girton, RA; Hansen, T; Hitchon, PW; McKay, TC; Wilkinson, TT | 1 |
| Harisdangkul, V; Myers, A; Rockhold, L | 1 |
| Balk, RA; Bone, RC; Clemmer, TP; Fisher, CJ; Metz, CA; Slotman, GJ | 1 |
| Al-Habet, SM; Rogers, HJ | 2 |
| Dreiling, DA; Huang, G; Papp, M; Premus, G; Robert, JH; Toledano, AE; Toth, LS | 2 |
| Ochudło, S | 1 |
| Hall, ED; Yonkers, PA | 1 |
| DeMasi, J; DiStefano, PM; Jusko, WJ; Kong, AN; Ludwig, EA; Middleton, E; Slaughter, RL | 1 |
| Della Cuna, GR; Pellegrini, A; Piazzi, M | 1 |
| Anderson, DK; Means, ED | 1 |
| Fukuda, T; Maeda, H; Mori, K; Ohmiya, A; Ohtsuka, Y; Toku, Y; Tsuji, Y; Yanai, M | 1 |
| Brooks, HL; Gross, GJ; Preuss, KC; Warltier, DC; Wynsen, JC | 1 |
| Brigden, ML; Erlichman, C; Geggie, P; Osoba, D; Pater, JL; Rusthoven, JJ; Willan, AR; Wilson, KS | 1 |
| Koyama, A; Shigematsu, H | 1 |
| Jusko, WJ; Kong, AN; Slaughter, RL | 1 |
| Dreiling, DA; Premus, G; Robert, JH; Toledano, AE; Toth, LS | 1 |
| Barth, J; Derendorf, H; Möllmann, C; Möllmann, H; Rohdewald, P; Verho, M | 1 |
| Mata, R; Muniain, MA; Pérez, JJ; Pozuelo, F; Rodríguez, MC; Rodríguez, MD; Romero, A | 1 |
| Bruno, A; Caiazza, A; Casadei, CL; Micheletti, G; Salzano de Luna, F; Santaniello, W; Zotti, GC | 1 |
| Murray, M; Slutsky, RA | 1 |
| Fiel, SB; Hoffman, IB | 1 |
| Brock-Utne, JG; Gaffin, SL; Gathiram, P; Wells, MT | 2 |
| Björkman, S; Idvall, J; Jonung, M | 1 |
| Honda, H; Jyoichi, T; Miyahara, T; Noda, Y; Shmojo, S | 1 |
| Cohen, IA; Johnson, CE; McMahon, RE; Michelini, TJ | 1 |
| Brass, C; Jusko, WJ; Kandrotas, RJ; Slaughter, RL | 1 |
| Alvinerie, M; Autefage, A; Oukessou, M; Toutain, PL | 1 |
| Izumi, M; Kakezono, F; Kiriyama, T; Morimoto, I; Morita, S; Nagataki, S; Nagayama, Y; Ohtakara, S; Okamoto, S; Yokoyama, N | 1 |
| Baethge, BA; Lidsky, MD | 1 |
| Flombaum, CD; Schroy, P; Vanamee, P; Watson, R | 1 |
| Alvinerie, M; Fayolle, PM; Koritz, GD; Toutain, PL | 1 |
| Oliver, RP | 1 |
| Zarro, VJ | 1 |
| Iizuka, H; Iwasaki, Y; Kadoya, S; Yamamoto, T | 1 |
| Cohen, IA; Craft, DA; Johnson, CE; Lizer, MH | 1 |
| Hearron, MS; Metz, CA; Stubbs, DF | 1 |
| Haverly, RW; Mansfield, LE; Ting, S | 1 |
| Rosen, M; Swai, EA | 1 |
| Brooks, PA; Chandrasena, LG; Cleek, JL; Fettman, MJ; Hand, MS; Mason, RA; Phillips, RW | 1 |
| Koyama, S | 1 |
| Erlichman, C; Levitt, M; Osoba, D; Pater, JL; Willan, AR | 1 |
| McNamara, RM | 1 |
| Doezema, D | 1 |
| Arnold, PI; Bergman, R; Duncan, RC; Marcial, EH; Schein, RM; Schultz, D; Sprung, CL | 1 |
| Louw, AF; Schoeman, HS; van der Merwe, CJ; Welthagen, D | 1 |
| Bäckstrand, B; Jansson, I; Lennquist, S; Rammer, L | 2 |
| Derendorf, H; Möllmann, H; Rehder, J; Rohdewald, P; Schmidt, EW | 1 |
| Anderson, BD; Conradi, RA; Forbes, AD; Spilman, CH | 1 |
| Baylis, EM; Chakraborty, J; Lawson, G; Lee, HA; Marks, V; Searle, M | 1 |
| Mathews, J; Rosenberg, RJ; Spencer, RP; Sziklas, JJ | 1 |
| Lawson, GJ | 1 |
| Niizuma, H; Shirane, R; Suzuki, J | 1 |
| Cowled, PA; Forbes, IJ; Mackenzie, L | 1 |
| Kitamura, F; Nishioka, K; Shimada, K; Suzuki, T | 1 |
| Shah, JA; Weber, DJ | 1 |
| Aasen, AO; Pillgram-Larsen, J; Röise, O; Ruud, TE; Stadaas, J | 1 |
| Fujimoto, S; Kishida, K; Nakamura, E; Ohya, M; Sasaki, M; Shirakawa, M; Taketomi, A | 1 |
| Furman, BL; McKechnie, K; Parratt, JR | 1 |
| Dahl, MV; Jacob, HS; Swanson, DL | 1 |
| Baylis, EM; Shipley, ME; Williams, IA | 1 |
| Gillick, JS | 1 |
| Bird, CC; Dyson, JE; McLaughlin, JB; Quirke, P; Surrey, CR | 1 |
| Lenoir, G; Pecquinot, MA; Perignon, F | 1 |
| Wyllie, AH | 1 |
| Braughler, JM; Hall, ED | 3 |
| DeLustro, F; LeRoy, EC; Lurie, DP | 1 |
| Ahmed, T; King, MM; Krainson, JP | 1 |
| Abbott, AC; Bird, CC; Blewitt, RW | 1 |
| Archer, LT; Beller, BK; Flournoy, DJ; Hinshaw, LB | 1 |
| Creighton, MO; Sanwal, M; Stewart-DeHaan, PJ; Trevithick, JR | 1 |
| Brackett, DJ; Schaefer, CF; Wilson, MF | 1 |
| Archer, LT; Beller, BK; Hinshaw, LB; Kosanke, SD; Passey, RB | 1 |
| Buddenhagen, JD; Hsu, LC; Pyter, RA | 1 |
| O'Keeffe, PJ | 1 |
| Cheney, FW; Gates, S; Huang, T | 1 |
| Archer, LT; Beller, BK; Flournoy, DJ; Hinshaw, LB; Passey, RB | 1 |
| Magnani, B; Maresta, A; Melandri, G; Tartagni, F | 2 |
| Ebling, WF; Jusko, WJ; Szefler, SJ | 1 |
| Abraham, WM; Ahmed, T; Delehunt, JC; Yerger, L | 1 |
| Braughler, JM; Hall, ED; Wolf, DL | 1 |
| Anderson, BD; Conradi, RA; Lambert, WJ | 1 |
| Chiu, CC; Imataka, K; Isobe, M; Nagai, R; Ohuchi, Y; Ueda, S; Yamaoki, K; Yazaki, Y | 1 |
| Birkeland, S; Bugge-Asperheim, B; Geiran, O; Svennevig, JL; Vaage, J | 1 |
| Coulson, A | 1 |
| Boghossian, SH; Isenberg, DA; Segal, AW; Snaith, ML; Wright, G | 1 |
| Hughes, GS | 1 |
| Ajao, A; Ajao, OG; Johnson, T | 1 |
| Nakagawa, H; Oikawa, S; Sagae, Y; Tomabechi, N; Tsurufuji, S | 1 |
| Klaustermeyer, WB; Kuhn, GJ; Santiago, SM; Tanaka, RM; Williams, RE | 1 |
| Cucin, RL; Graham, M; Guthrie, RH | 1 |
| Packard, BD; Weiler, JM | 1 |
| Archer, LT; Beller-Todd, BK; Hinshaw, LB | 1 |
| Carini, GC; Franchi, R; Magnani, B; Maresta, A; Melandri, G; Monetti, N; Tartagni, F | 1 |
| Almazan Enríquez, A; Gómez Alonso, A; Lozano Sánchez, F; Ramos Boyero, M | 1 |
| Barcelo, R; Bastien, E; Beaudry, C; Cardinal, J; Carriere, S; Dandavino, R; Friborg, J; Girard, R; Houde, M; Laplante, L; Ouimet, D | 1 |
| Archer, LT; Beller-Todd, BK; Benjamin, B; Coalson, JJ; Flournoy, DJ; Hinshaw, LB; Passey, R; White, GL | 1 |
| Hattori, K; Nakajima, E; Oshima, T | 1 |
| Becker, H; Carlson, RW; Henning, RJ; Kalter, ES; Thijs, L; Vincent, JL; Weil, MH | 1 |
| Bellingham, AJ; Brada, M; Robinson, LA | 1 |
| Bate, LR; Wentworth, P | 1 |
| Bowen, JC; Payne, JG | 1 |
| Altman, LC; Hairfield, WM; Hill, JS; Mullarkey, MF | 1 |
| Chapel, N; Freedman, MD; Gerber, JG; Schocket, AL | 1 |
| Ewert, A; MacDonald, E; Reitmeyer, JC | 1 |
| Birkeland, S; Bjørgo, S; Bugge-Asperheim, B; Svennevig, JL | 1 |
| Epstein, N; Hood, DC; Ransohoff, J | 1 |
| Connors, RH; Coran, AG; Drongowski, RA; Weintraub, WH; Wesley, JR | 1 |
| Anderson, BD; Taphouse, V | 1 |
| Hashimoto, H; Nakamura, R; Sakuma, S; Tsutaho, K | 1 |
| De Pablo, P; Monreal, I; Pérez Afonso, F; Rodríguez de la Nuez, AL; Sierrasesúmaga, L; Villa Elízaga, I | 1 |
| Baylis, EM; English, J; Williams, IA | 1 |
| Archer, LT; Beller-Todd, BK; Benjamin, B; Flournoy, DJ; Hinshaw, LB; Passey, R | 1 |
| Ayabe, H; Cooper, JD; Goldberg, M; Lima, O; Luk, SC; Peters, WJ; Townsend, E | 1 |
| Anderson, GG; Kaiser, DG; Rotchell, Y | 1 |
| Nail, SL; Puchala, AH; Townsend, RJ | 1 |
| Kaplan, JE | 1 |
| Andersen, RC; O'Brien, TJ; Rao, KV | 1 |
| Johnson, RB; Lazarus, GS | 1 |
| El-Mofty, SK; Eratalay, YK; Halberg, F; Haus, E; Nelson, W; Rosenberg, GD; Simmons, DJ | 1 |
| Connell, RS; Minnear, FL | 1 |
| Argenta, LC; Oneal, RM | 1 |
| Baylis, EM; Chakraborty, J; English, J; Marks, V; Williams, IA | 1 |
| Beckman, CB; Dietzman, RH; Lillehei, RC; Romero, LH; Shatney, CH | 1 |
| Frater, RW; Lin, Yt; Oka, Y; Sklar, G | 1 |
| Hashimoto, M; Katori, M; Shinozaki, Y | 1 |
| Guiraud, MP; Saint-André, JP; Tuchais, E; Vidal, JF | 1 |
| Della-Coletta, AA; Ferry, JJ; VanderLugt, JT; Weber, DJ | 1 |
| Cabanillas, F; Hagemeister, FB; Hill, D; McLaughlin, P; Moore, DF; Rodriguez, MA; Romaguera, JE; Sarris, AH; Swan, F; Younes, A | 1 |
| Camara, DS; Jusko, WJ; Kong, AN; Ludwig, EA | 1 |
| Delashaw, JB; Fessler, RG; Glasser, RS; Knego, RS | 1 |
| Horrocks, LA; Murphy, EJ; Rosenberger, TA; Slivka, AP | 1 |
| Godard, PH; Harry, JD; Leophonte, P; Muir, JF; Racineux, JL | 1 |
| Aoki, M; Iwata, H; Kato, F; Mimatsu, K | 1 |
| Daley-Yates, PT; Parker, TJ; Wood, SA | 1 |
| Brooks, CD; Daley-Yates, PT; Gregory, AJ | 1 |
| Cabanillas, F; Rodriguez-Monge, EJ | 1 |
| Jongen, PJ; Lagerwerf, AJ; Maes, RA; Maljers, L; Nibbering, NM; Van den Borg, N; Verwey-van Wissen, CP; Vree, TB | 1 |
| Mehvar, R | 1 |
| Dann, RO; Hoganson, DA; Mehvar, R | 1 |
| BOTHIER, F; BRUNAT, M; CROIZAT, P; PALIARD, P; REVOL, L | 1 |
| FUNCK, FW; ZICHA, L | 1 |
| GIGNOUX, M; POMMATAU, E; REVILLARD, JP | 1 |
| COOK, AW; LIN, TH; SPARACIO, RR | 1 |
| Chan, SC; Dmitrovic, J; Metz, LM; Morrow, SA; Stoian, CA | 1 |
| Balbach, S; Barth, J; Derendorf, H; Madabushi, R; Möllenhoff, G; Möllmann, H; Nagaraja, NV; Schumann, R; Winkler, J | 1 |
| Gordeladze, JO; Holten, T; Sellevold, OF | 1 |
| Aydin, S; Dührsen, U; Nückel, H | 1 |
| Sibille, Y; Sohy, C; Vandenplas, O | 1 |
| Paparella, S | 1 |
| Dawley, JD; Moeller-Bertram, T; Patel, PM; Wallace, MS | 1 |
| Altuntaş, F; Bozdağ, SC; Demiriz, IŞ; Durgun, G; Koçubaba, S; Sarıca, A; Tekgündüz, E | 1 |
| Chourdakis, E; Koniari, I; Kounis, NG; Soufras, GD | 1 |
| Desai, CS; Szempruch, KR; Vonderau, JS | 1 |
| Jie, C; Li-Po, H; Yu, Z; Yuan-da, Z | 1 |
| Lan, L; Ma, B; Ren, G; Xu, J; Zhang, Q | 1 |
| Bai, Y; Chen, K; Fan, Z; Jiao, K; Li, B; Li, J; Li, M; Liu, C; Wang, H; Wei, X; Wu, J; Yang, H; Zhai, X; Zhang, H; Zhou, T | 1 |
| Al-Hakkani, MF | 1 |
3 review(s) available for methylprednisolone hemisuccinate and methylprednisolone
| Article | Year |
|---|---|
Steroids after spinal cord injury.
Topics: Acute Disease; Brain Injuries; Clinical Trials as Topic; Drug Administration Schedule; Humans; Methylprednisolone; Methylprednisolone Hemisuccinate; Naloxone; Spinal Cord Injuries; Time Factors | 1990 |
Effects of high-to-mega-dose synthetic corticosteroids on multiple sclerosis patients with special reference to cerebrospinal fluid antibodies to myelin basic protein.
Topics: Antibodies; Dose-Response Relationship, Drug; Humans; Methylprednisolone; Methylprednisolone Hemisuccinate; Multiple Sclerosis; Myelin Basic Protein; Prednisone | 1987 |
Pulse therapy. Therapeutic efficacy in the treatment of pyoderma gangrenosum.
Topics: Adolescent; Adult; Female; Humans; Immunoglobulins; Infusions, Parenteral; Lymphocytes; Macrophages; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Middle Aged; Monocytes; Neutrophils; Pyoderma; Skin Ulcer | 1982 |
31 trial(s) available for methylprednisolone hemisuccinate and methylprednisolone
| Article | Year |
|---|---|
Pharmacokinetics and pharmacodynamics of methylprednisolone in obesity.
Topics: Adult; Basophils; Circadian Rhythm; Drug Evaluation; Histamine; Humans; Hydrocortisone; Leukocyte Count; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Obesity; Regression Analysis; T-Lymphocytes, Helper-Inducer | 1991 |
Steroids after spinal cord injury.
Topics: Acute Disease; Brain Injuries; Clinical Trials as Topic; Drug Administration Schedule; Humans; Methylprednisolone; Methylprednisolone Hemisuccinate; Naloxone; Spinal Cord Injuries; Time Factors | 1990 |
Methylprednisolone as palliative therapy for female terminal cancer patients. The Methylprednisolone Female Preterminal Cancer Study Group.
Topics: Double-Blind Method; Female; Humans; Methylprednisolone; Methylprednisolone Hemisuccinate; Multicenter Studies as Topic; Neoplasms; Palliative Care; Quality of Life; Randomized Controlled Trials as Topic; Terminal Care | 1989 |
Lupus nephritis: efficacy of monthly pulse therapy with intravenous methylprednisolone.
Topics: Acute Disease; Adolescent; Adult; Child; Creatinine; Drug Administration Schedule; Drug Evaluation; Female; Humans; Infusions, Intravenous; Lupus Nephritis; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Middle Aged; Random Allocation; Time Factors | 1989 |
Methylprednisolone pharmacokinetics after intravenous and oral administration.
Topics: Administration, Oral; Adult; Biological Availability; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Female; Humans; Injections, Intravenous; Male; Methylprednisolone; Methylprednisolone Hemisuccinate | 1989 |
[Effect of treatment with Encorton (Polfa), Solu-Medrol and Encorton and Cyclophosphamide and Encorton on the production of immunoglobulin G in the central nervous system in multiple sclerosis].
Topics: Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Humans; Immunoglobulin G; Methylprednisolone; Methylprednisolone Hemisuccinate; Multiple Sclerosis; Poland; Prednisone | 1989 |
Effect of methylprednisolone sodium succinate on quality of life in preterminal cancer patients: a placebo-controlled, multicenter study. The Methylprednisolone Preterminal Cancer Study Group.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Double-Blind Method; Female; Humans; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Middle Aged; Multicenter Studies as Topic; Neoplasms; Quality of Life; Randomized Controlled Trials as Topic | 1989 |
Methylprednisolone as an intervention following myocardial infarction. The Solu-Medrol Sterile Powder AMI Studies Group.
Topics: Arrhythmias, Cardiac; Clinical Trials as Topic; Double-Blind Method; Female; Follow-Up Studies; Heart Arrest; Humans; Injections, Intravenous; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Middle Aged; Myocardial Infarction; Regression Analysis | 1986 |
Failure of methylprednisolone acetate to prolong the antinauseant effect of intravenous methylprednisolone sodium succinate in patients receiving chemotherapy.
Topics: Adult; Antineoplastic Agents; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Humans; Methylprednisolone; Methylprednisolone Acetate; Methylprednisolone Hemisuccinate; Nausea; Random Allocation; Vomiting | 1988 |
Prevention of pulmonary complications by 6-methylprednisolone in major abdominal surgery.
Topics: Abdomen; Bicarbonates; Carbon Dioxide; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Middle Aged; Oxygen; Postoperative Complications; Random Allocation; Respiratory Tract Diseases | 1988 |
Ketoconazole effects on methylprednisolone disposition and their joint suppression of endogenous cortisol.
Topics: Adult; Analysis of Variance; Clinical Trials as Topic; Humans; Hydrocortisone; Ketoconazole; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Random Allocation; Time Factors | 1987 |
Treatment of Graves' ophthalmopathy with high-dose intravenous methylprednisolone pulse therapy.
Topics: Adult; Aged; Clinical Trials as Topic; Female; Graves Disease; Humans; Infusions, Intravenous; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Middle Aged; Oculomotor Muscles; Orbit; Tomography, X-Ray Computed; Vision Tests | 1987 |
Significance of infarct site and methylprednisolone on survival following acute myocardial infarction.
Topics: Clinical Trials as Topic; Double-Blind Method; Follow-Up Studies; Heart Failure; Humans; Methylprednisolone; Methylprednisolone Hemisuccinate; Myocardial Infarction; Myocardium | 1986 |
Superiority of methylprednisolone sodium succinate over low dose metoclopramide hydrochloride in the prevention of nausea and vomiting produced by cancer chemotherapy.
Topics: Antineoplastic Agents; Anxiety; Gastrointestinal Diseases; Humans; Methylprednisolone; Methylprednisolone Hemisuccinate; Metoclopramide; Nausea; Sleep Stages; Vomiting | 1986 |
A double-blind placebo-controlled trial of methylprednisolone pulse therapy in active rheumatoid disease.
Topics: Adult; Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Infusions, Parenteral; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Middle Aged; Random Allocation | 1982 |
Naloxone and methylprednisolone sodium succinate enhance sympathomedullary discharge in patients with septic shock.
Topics: Bacteria; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Epinephrine; Heart Rate; Hemodynamics; Humans; Methylprednisolone; Methylprednisolone Hemisuccinate; Naloxone; Norepinephrine; Shock, Septic; Stroke Volume; Vascular Resistance | 1984 |
Methylprednisolone sodium succinate (Solu-Medrol) in the treatment of typhoid perforation (a preliminary report).
Topics: Adolescent; Adult; Child; Child, Preschool; Clinical Trials as Topic; Female; Humans; Ileal Diseases; Intestinal Perforation; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Random Allocation; Sepsis; Shock, Septic; Typhoid Fever | 1984 |
Intravenous methylprednisolone in adults in status asthmaticus. Comparison of two dosages.
Topics: Adult; Asthma; Clinical Trials as Topic; Double-Blind Method; Humans; Infusions, Parenteral; Methylprednisolone; Methylprednisolone Hemisuccinate; Middle Aged; Prospective Studies; Random Allocation; Respiratory Function Tests | 1982 |
Effects of methylprednisolone on P50, 2,3 diphosphoglycerate and arteriovenous oxygen difference in acute myocardial infarction.
Topics: Adult; Aged; Diphosphoglyceric Acids; Double-Blind Method; Female; Hemoglobins; Humans; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Middle Aged; Myocardial Infarction; Oxygen; Placebos | 1980 |
Efficacy of steroids in the treatment of lung contusion.
Topics: Clinical Trials as Topic; Hemodynamics; Humans; Lung Injury; Methylprednisolone; Methylprednisolone Hemisuccinate; Oxygen Consumption; Random Allocation; Thoracic Injuries; Wounds, Nonpenetrating | 1980 |
Gastrointestinal bleeding in patients with spinal cord trauma. Effects of steroids, cimetidine, and mini-dose heparin.
Topics: Adrenal Cortex Hormones; Cimetidine; Gastrointestinal Hemorrhage; Guanidines; Heparin; Humans; Methylprednisolone; Methylprednisolone Hemisuccinate; Spinal Cord Injuries | 1981 |
Attenuation of stress and hemodynamic stability.
Topics: Adult; Aged; Clinical Trials as Topic; Female; Heart Valve Diseases; Hemodynamics; Humans; Hypertension; Intraoperative Complications; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Middle Aged; Tachycardia | 1982 |
Pilot study of the pharmacokinetics of methylprednisolone after single and multiple intravenous doses of methylprednisolone sodium succinate and methylprednisolone suleptanate to healthy volunteers.
Topics: Adult; Humans; Injections, Intravenous; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Pilot Projects; Prodrugs; Single-Blind Method | 1994 |
A phase II trial of oral etoposide with mitoxantrone and ifosfamide/mesna consolidated with intravenous etoposide, methylprednisolone, high-dose arabinoside, and cisplatin as salvage therapy for relapsing and/or refractory lymphomas.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cross-Over Studies; Cytarabine; Etoposide; Female; Humans; Ifosfamide; Lymphoma; Male; Mesna; Methylprednisolone; Methylprednisolone Hemisuccinate; Middle Aged; Mitoxantrone; Prednisone; Salvage Therapy | 1994 |
Seventy-two hour comparison of methylprednisolone suleptanate and methylprednisolone sodium succinate in patients with acute asthma.
Topics: Acute Disease; Adolescent; Adult; Anti-Inflammatory Agents; Asthma; Double-Blind Method; Female; Humans; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Middle Aged; Prodrugs; Respiratory Function Tests | 1996 |
A comparative population pharmacokinetic analysis for methylprednisolone following multiple dosing of two prodrugs in patients with acute asthma.
Topics: Area Under Curve; Asthma; Bayes Theorem; Body Weight; Chromatography, High Pressure Liquid; Double-Blind Method; Female; Glucocorticoids; Half-Life; Humans; Injections, Intravenous; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Prodrugs; Sex Factors; Smoking | 1997 |
Pharmacokinetic and pharmacodynamic assessment of bioavailability for two prodrugs of methylprednisolone.
Topics: Adolescent; Adult; Analysis of Variance; Area Under Curve; Basophils; Biological Availability; Blood Glucose; Chromatography, High Pressure Liquid; Cross-Over Studies; Glucocorticoids; Histamine; Humans; Leukocyte Count; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Middle Aged; Prodrugs; Radioimmunoassay; Single-Blind Method; Therapeutic Equivalency | 1997 |
High-performance liquid-chromatographic-atmospheric-pressure chemical-ionization ion-trap mass-spectrometric identification of isomeric C6-hydroxy and C20-hydroxy metabolites of methylprednisolone in the urine of patients receiving high-dose pulse therapy
Topics: Anti-Inflammatory Agents; Chromatography, High Pressure Liquid; Glucuronates; Humans; Mass Spectrometry; Methylprednisolone; Methylprednisolone Hemisuccinate; Oxidation-Reduction; Prodrugs; Stereoisomerism; Water | 1999 |
The bioavailability of IV methylprednisolone and oral prednisone in multiple sclerosis.
Topics: Administration, Oral; Adult; Anti-Inflammatory Agents; Area Under Curve; Biological Availability; Biotransformation; Female; Humans; Immunosuppressive Agents; Infusions, Intravenous; Liver; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Middle Aged; Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting; Prednisolone; Prednisone | 2004 |
Rituximab plus ASHAP for the treatment of patients with relapsed or refractory aggressive non-Hodgkin's lymphoma: a single-centre study of 20 patients.
Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cytarabine; Disease-Free Survival; Doxorubicin; Drug Resistance, Neoplasm; Female; Humans; Lymphoma, Non-Hodgkin; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Middle Aged; Nausea; Neoplasm Recurrence, Local; Neutropenia; Prognosis; Retrospective Studies; Rituximab; Salvage Therapy; Thrombocytopenia; Treatment Outcome | 2007 |
Usefulness of oral macrogol challenge in anaphylaxis after intra-articular injection of corticosteroid preparation.
Topics: Administration, Oral; Adrenal Cortex Hormones; Adult; Anaphylaxis; Anti-Inflammatory Agents; Female; Histamine H1 Antagonists; Humans; Injections, Intra-Articular; Methylprednisolone; Methylprednisolone Acetate; Methylprednisolone Hemisuccinate; Polyethylene Glycols; Skin Tests | 2008 |
157 other study(ies) available for methylprednisolone hemisuccinate and methylprednisolone
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Recovery from lethal Escherichia coli shock in dogs.
Topics: Animals; Blood Glucose; Carbon Dioxide; Dogs; Drug Therapy, Combination; Escherichia coli Infections; Female; Gentamicins; Hematocrit; Hydrogen-Ion Concentration; Insulin; Lactates; Leukocyte Count; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Oxygen; Shock, Septic | 1979 |
[Study of 4 cases of massive acute interstitial pathology of the lungs (adult respiratory distress syndrome or ARDS)].
Topics: Adult; Anti-Bacterial Agents; Blood Transfusion; Dextrans; Female; Humans; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Positive-Pressure Respiration; Respiratory Distress Syndrome | 1979 |
Protection of primate lung from stored-blood perfusion by peptidase inhibition and target membrane stabilization.
Topics: Animals; Aprotinin; Hemodynamics; Male; Membranes; Methylprednisolone; Methylprednisolone Hemisuccinate; Papio; Perfusion; Pulmonary Edema; Respiratory Distress Syndrome; Transfusion Reaction | 1978 |
Comparison of corticosteroids and prostaglandins in treatment of hemorrhagic shock.
Topics: Animals; Cardiac Output; Dogs; Methylprednisolone; Methylprednisolone Hemisuccinate; Microcirculation; Prostaglandins E; Shock, Hemorrhagic; Vascular Resistance | 1979 |
Reduction of experimental myocardial infarct size by combined treatment with methylprednisolone sodium succinate and betahistine hydrochloride.
Topics: Animals; Betahistine; Blood Gas Analysis; Coronary Vessels; Dogs; Hemodynamics; L-Lactate Dehydrogenase; Methylprednisolone; Methylprednisolone Hemisuccinate; Myocardial Infarction; Organ Size; Pyridines | 1978 |
Effect of prostaglandin E1 and steroid combination in the treatment of hemorrhagic shock.
Topics: Animals; Cathepsins; Dogs; Hemodynamics; Methylprednisolone; Methylprednisolone Hemisuccinate; Prostaglandins E; Shock, Hemorrhagic; Splenectomy | 1978 |
Effects of methylprednisolone sodium succinate on clearance of live E coli from the peripheral blood of dogs.
Topics: Animals; Blood; Blood Glucose; Body Temperature; Dogs; Escherichia coli; Hematocrit; Leukocyte Count; Methylprednisolone; Methylprednisolone Hemisuccinate; Time Factors | 1979 |
Methylprednisolone hemisuccinate and metabolites in urine from patients receiving high-dose corticosteroid therapy.
Topics: Arthritis, Rheumatoid; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Humans; Hydrolysis; Methylprednisolone; Methylprednisolone Hemisuccinate; Spectrophotometry, Ultraviolet | 1992 |
Disposition of methylprednisolone and its sodium succinate prodrug in vivo and in perfused liver of rats: nonlinear and sequential first-pass elimination.
Topics: Animals; In Vitro Techniques; Liver; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Models, Biological; Perfusion; Prodrugs; Rats; Rats, Inbred Strains | 1991 |
Experience with salvage regimens at M.D. Anderson Hospital.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cytarabine; Drug Evaluation; Etoposide; Follow-Up Studies; Humans; Ifosfamide; Lymphoma; Lymphoma, Non-Hodgkin; Mesna; Methotrexate; Methylprednisolone; Methylprednisolone Hemisuccinate; Mitoguazone; Mitoxantrone; Remission Induction; Survival Rate | 1991 |
Efficacy of steroids and hyperbaric oxygen on survival of dorsal skin flaps in rats.
Topics: Animals; Graft Survival; Hyperbaric Oxygenation; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Rats; Rats, Inbred Strains; Surgical Flaps | 1990 |
Steroids decrease granulocyte membrane fluidity, while phorbol ester increases membrane fluidity. Studies using electron paramagnetic resonance.
Topics: Electron Spin Resonance Spectroscopy; Estrogens, Conjugated (USP); Granulocytes; Humans; Ibuprofen; In Vitro Techniques; Membrane Fluidity; Methylprednisolone; Methylprednisolone Hemisuccinate; Tetradecanoylphorbol Acetate | 1990 |
Pharmacokinetics of methylprednisolone sodium succinate and methylprednisolone in patients undergoing cardiopulmonary bypass.
Topics: Adult; Aged; Cardiopulmonary Bypass; Chromatography, High Pressure Liquid; Half-Life; Humans; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Middle Aged; Time Factors | 1990 |
The fate of soluble steroids within breast prostheses in humans.
Topics: Breast; Diffusion; Female; Humans; Hydrolysis; Methylprednisolone; Methylprednisolone Hemisuccinate; Prostheses and Implants; Prosthesis Design; Surgery, Plastic; Wound Healing | 1990 |
Corticosteroids do not inhibit acute pulmonary response to fat embolism.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cardiac Output; Dogs; Embolism, Fat; Methylprednisolone; Methylprednisolone Hemisuccinate; Premedication; Pulmonary Circulation; Pulmonary Embolism; Thromboxane B2; Vascular Resistance | 1990 |
Steroids for Pneumocystis carinii pneumonia and respiratory failure in the acquired immunodeficiency syndrome. A reassessment.
Topics: Acquired Immunodeficiency Syndrome; Drug Therapy, Combination; Female; Humans; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Pentamidine; Pneumonia, Pneumocystis; Recurrence; Respiratory Insufficiency; Trimethoprim, Sulfamethoxazole Drug Combination | 1990 |
Effects on peritoneal proteolysis and hemodynamics by high doses of methyl-prednisolone in experimental acute pancreatitis.
Topics: Acute Disease; Amylases; Animals; Hemodynamics; Kallikreins; Kinins; Methylprednisolone; Methylprednisolone Hemisuccinate; Pancreas; Pancreatitis; Peritoneum; Swine; Trypsin | 1986 |
Steroids and cardioplegia: effects of glucocorticoids upon vascular resistance during cardioplegic perfusion.
Topics: Animals; Cardioplegic Solutions; Coronary Circulation; Coronary Vasospasm; Dose-Response Relationship, Drug; Filtration; Heart Arrest, Induced; In Vitro Techniques; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Myocardium; Perfusion; Rats; Rats, Inbred Strains; Vascular Resistance | 1987 |
Comparative incidence of experimental fascioliasis on corticosteroid pharmacokinetics in sheep.
Topics: Animals; Fascioliasis; Male; Metabolic Clearance Rate; Methylprednisolone; Methylprednisolone Hemisuccinate; Prednisone; Sheep; Sheep Diseases | 1989 |
Methylprednisolone in spinal cord compression.
Topics: Animals; Evoked Potentials, Somatosensory; Female; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Regional Blood Flow; Sheep; Spinal Cord; Spinal Cord Compression | 1989 |
Bell-shaped concentration-response curve for myocardial stimulation by glucocorticoids. An experimental study in the rat.
Topics: Animals; Coronary Circulation; Dose-Response Relationship, Drug; Energy Metabolism; Heart; Heart Rate; In Vitro Techniques; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Myocardial Contraction; Myocardium; Rats; Rats, Inbred Strains; Stimulation, Chemical | 1989 |
Sepsis syndrome: a valid clinical entity. Methylprednisolone Severe Sepsis Study Group.
Topics: Body Temperature; Double-Blind Method; Hemodynamics; Humans; Hypotension; Methylprednisolone; Methylprednisolone Hemisuccinate; Middle Aged; Prospective Studies; Random Allocation; Respiratory Distress Syndrome; Sepsis; Shock, Septic; Syndrome | 1989 |
The pancreas and oxygen consumption (Part 2). Steroids do not modify resting pancreatic oxygen consumption in dogs: a preliminary report.
Topics: Animals; Dogs; Female; Methylprednisolone; Methylprednisolone Hemisuccinate; Oxygen Consumption; Pancreas; Shock | 1989 |
Two chromatographic methods for the determination of corticosteroids in human biological fluids: pharmacokinetic applications.
Topics: Adrenal Cortex Hormones; Adult; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Female; Humans; Hydrolysis; Injections, Intravenous; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Prednisolone; Saliva; Spectrophotometry, Ultraviolet; Temperature | 1989 |
Comparison of two ester prodrugs of methylprednisolone on early neurologic recovery in a murine closed head injury model.
Topics: Animals; Brain Concussion; Craniocerebral Trauma; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Mice; Mice, Inbred Strains; Prodrugs | 1989 |
Pharmacokinetics and pharmacodynamic modeling of direct suppression effects of methylprednisolone on serum cortisol and blood histamine in human subjects.
Topics: Adult; Analysis of Variance; Basophils; Blood Proteins; Chromatography, High Pressure Liquid; Circadian Rhythm; Histamine; Humans; Hydrocortisone; Least-Squares Analysis; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Models, Biological; Protein Binding; Radioimmunoassay | 1989 |
Iron-induced lipid peroxidation in spinal cord: protection with mannitol and methylprednisolone.
Topics: Animals; Cats; Female; Ferrous Compounds; Hydroxides; Hydroxyl Radical; Iron; Lipid Peroxides; Male; Malondialdehyde; Mannitol; Methylprednisolone; Methylprednisolone Hemisuccinate; Sodium Chloride; Sodium-Potassium-Exchanging ATPase; Spinal Cord | 1985 |
[Pulse methylprednisolone therapy in children with idiopathic thrombocytopenic purpura].
Topics: Adolescent; Child; Child, Preschool; Drug Administration Schedule; Female; Humans; Infant; Infusions, Intravenous; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Purpura, Thrombocytopenic | 1988 |
Steroid-induced enhancement of functional recovery of postischemic, reperfused myocardium in conscious dogs.
Topics: Animals; Consciousness; Coronary Disease; Dogs; Hemodynamics; Methylprednisolone; Methylprednisolone Hemisuccinate; Myocardial Contraction; Myocardial Reperfusion; Time Factors | 1988 |
Therapeutic effect of cyclosporin A and steroid on serum sickness type nephritis in the rat. 2. Suppressive effect on full-blown proliferative glomerulonephritis.
Topics: Animals; Complement C3; Cyclosporins; Glomerulonephritis; Immunoglobulin G; Kidney Glomerulus; Methylprednisolone; Methylprednisolone Hemisuccinate; Rats; Rats, Inbred F344; Serum Sickness | 1988 |
The pancreas and oxygen consumption: 3. Do steroids improve pancreatic O2 consumption response to hypovolemia? Final Report.
Topics: Animals; Disease Models, Animal; Dogs; Female; Humans; Methylprednisolone; Methylprednisolone Hemisuccinate; Oxygen Consumption; Pancreas; Pancreatic Diseases; Shock | 1988 |
Simultaneous analysis of methylprednisolone hemisuccinate, cortisol and methylprednisolone by normal-phase high-performance liquid chromatography in human plasma.
Topics: Adult; Chromatography, High Pressure Liquid; Humans; Hydrocortisone; Indicators and Reagents; Male; Methylprednisolone; Methylprednisolone Hemisuccinate | 1988 |
Steroids do not alter pancreatic blood supply in hypovolemic dogs: implications on steroid action in acute pancreatitis.
Topics: Acute Disease; Animals; Dogs; Methylprednisolone; Methylprednisolone Hemisuccinate; Pancreas; Pancreatitis; Shock; Splanchnic Circulation | 1988 |
Comparative pharmacokinetics of methylprednisolone phosphate and hemisuccinate in high doses.
Topics: Adolescent; Adult; Humans; Hydrocortisone; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Saliva | 1988 |
[Effect of corticosteroids, quinacrine and L-652, 731 on experimental aggregation of polymorphonuclear leukocytes induced by complement and platelet activating factor (PAF)].
Topics: Agranulocytosis; Animals; Cell Aggregation; Complement System Proteins; Furans; Methylprednisolone; Methylprednisolone Hemisuccinate; Neutropenia; Platelet Activating Factor; Quinacrine; Rabbits; Zymosan | 1988 |
Computed tomographic analysis of the effects of hyperosmolar mannitol and methylprednisolone on myocardial infarct size.
Topics: Animals; Cardiomegaly; Dogs; Dose-Response Relationship, Drug; Hemodynamics; Mannitol; Methylprednisolone; Methylprednisolone Hemisuccinate; Myocardial Infarction; Osmolar Concentration; Perfusion; Time Factors; Tomography, X-Ray Computed | 1985 |
Oral vs repository corticosteroid therapy in acute asthma.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Asthma; Female; Humans; Injections, Intramuscular; Injections, Intravenous; Male; Methylprednisolone; Methylprednisolone Acetate; Methylprednisolone Hemisuccinate; Middle Aged; Patient Compliance; Peak Expiratory Flow Rate; Recurrence | 1988 |
Prophylactic corticosteroid suppresses endotoxemia in heat-stressed primates.
Topics: Animals; Blood Pressure; Body Temperature; Chlorocebus aethiops; Endotoxins; Female; Heart Rate; Heat Exhaustion; Lipopolysaccharides; Male; Methylprednisolone; Methylprednisolone Hemisuccinate | 1988 |
Prophylactic corticosteroid increases survival in experimental heat stroke in primates.
Topics: Animals; Chlorocebus aethiops; Female; Heat Exhaustion; Immunoglobulin G; Lipopolysaccharides; Male; Methylprednisolone; Methylprednisolone Hemisuccinate | 1988 |
Determination of methylprednisolone in rat tissue by high-performance liquid chromatography.
Topics: Animals; Chromatography, High Pressure Liquid; Dexamethasone; Indicators and Reagents; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Rats; Rats, Inbred Strains; Subtilisins; Tissue Distribution | 1987 |
[Plasmapheresis-pulse therapy in chronic stage of Guillain-Barré syndrome--controlled study].
Topics: Activities of Daily Living; Adult; Chronic Disease; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Middle Aged; Plasmapheresis; Polyradiculoneuropathy | 1987 |
Compatibility of premixed theophylline and methylprednisolone sodium succinate intravenous admixtures.
Topics: Chromatography, High Pressure Liquid; Drug Combinations; Drug Incompatibility; Drug Stability; Infusions, Intravenous; Methylprednisolone; Methylprednisolone Hemisuccinate; Theophylline | 1987 |
Pharmacokinetics of methylprednisolone succinate, methylprednisolone, and lidocaine in the normal dog and during hemorrhagic shock.
Topics: Animals; Biological Availability; Dogs; Kinetics; Lidocaine; Liver Circulation; Metabolic Clearance Rate; Methylprednisolone; Methylprednisolone Hemisuccinate; Shock, Hemorrhagic | 1987 |
Intractable hiccups associated with high-dose intravenous methylprednisolone therapy.
Topics: Adult; Hiccup; Humans; Infusions, Parenteral; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Metoclopramide; Middle Aged | 1986 |
Treatment of acute obstructive renal failure with high-dose methylprednisolone.
Topics: Acute Kidney Injury; Aged; Edema; Female; Hodgkin Disease; Humans; Injections, Intravenous; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Ureteral Obstruction; Uterine Cervical Neoplasms | 1986 |
Pharmacokinetics of methylprednisolone, methylprednisolone sodium succinate, and methylprednisolone acetate in dogs.
Topics: Animals; Biological Availability; Dogs; Half-Life; Injections, Intramuscular; Injections, Intravenous; Kinetics; Male; Methylprednisolone; Methylprednisolone Acetate; Methylprednisolone Hemisuccinate; Models, Biological | 1986 |
Chronic lymphocytic leukemia following treatment of status asthmaticus with systemic steroids.
Topics: Aged; Asthma; Humans; Leukemia, Lymphoid; Lung Diseases, Obstructive; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Status Asthmaticus | 1986 |
Steroid pulse therapy.
Topics: Anemia, Aplastic; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Drug Administration Schedule; Humans; Lupus Erythematosus, Systemic; Methylprednisolone; Methylprednisolone Hemisuccinate; Purpura, Thrombocytopenic; Skin Diseases | 1986 |
Morphometric assessment of drug effects in experimental spinal cord injury.
Topics: Animals; Axons; Leucine; Leupeptins; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Rats; Rats, Inbred Strains; Spinal Cord Injuries | 1986 |
Compatibility of aminophylline and methylprednisolone sodium succinate intravenous admixtures.
Topics: Aminophylline; Drug Incompatibility; Drug Stability; Hydrogen-Ion Concentration; Infusions, Parenteral; Methylprednisolone; Methylprednisolone Hemisuccinate; Solutions | 1986 |
Anaphylaxis caused by the sodium succinate ester of hydrocortisone and methylprednisolone.
Topics: Anaphylaxis; Asthma; Drug Interactions; Female; Humans; Hydrocortisone; Methylprednisolone; Methylprednisolone Hemisuccinate; Middle Aged; Status Asthmaticus | 1986 |
An attempt to develop a model to study the effects of intrathecal steroids.
Topics: Animals; Arachnoiditis; Cefoxitin; Desoxycorticosterone; Disease Models, Animal; Drug Interactions; Injections, Spinal; Male; Meningitis; Meningitis, Aseptic; Methylprednisolone; Methylprednisolone Hemisuccinate; Rats; Rats, Inbred Strains; Spinal Cord Diseases; Triamcinolone Acetonide | 1986 |
Methylprednisolone and gentamicin effects on hepatosplanchnic blood flow and carbohydrate metabolism in endotoxemic Yucatan miniature pigs.
Topics: Animals; Blood Flow Velocity; Blood Pressure; Drug Therapy, Combination; Female; Gentamicins; Glucose; Insulin; Lactates; Liver; Liver Circulation; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Oxygen; Shock, Septic; Splanchnic Circulation; Swine; Swine Diseases; Swine, Miniature | 1986 |
Effects of methylprednisolone on renal nerve response to stimulation of medullary pressor area in endotoxin-induced hypotension.
Topics: Animals; Blood Pressure; Electric Stimulation; Kidney; Male; Medulla Oblongata; Methylprednisolone; Methylprednisolone Hemisuccinate; Neural Pathways; Rabbits; Shock, Septic; Sympathetic Nervous System; Thoracic Nerves | 1986 |
Anaphylaxis after intravenous corticosteroid administration.
Topics: Aged; Anaphylaxis; Asthma; Drug Hypersensitivity; Emergencies; Female; Humans; Infusions, Intravenous; Methylprednisolone; Methylprednisolone Hemisuccinate | 1986 |
Anaphylaxis following administration of intravenous methylprednisolone sodium succinate.
Topics: Adult; Anaphylaxis; Asthma; Humans; Injections, Intravenous; Male; Methylprednisolone; Methylprednisolone Hemisuccinate | 1987 |
Complement activation and corticosteroid therapy in the development of the adult respiratory distress syndrome.
Topics: Complement Activation; Dexamethasone; Humans; Methylprednisolone; Methylprednisolone Hemisuccinate; Middle Aged; Respiratory Distress Syndrome; Shock, Septic | 1987 |
Adult respiratory distress syndrome in cases of severe trauma--the prophylactic value of methylprednisolone sodium succinate.
Topics: Adult; Humans; Methylprednisolone; Methylprednisolone Hemisuccinate; Middle Aged; Prospective Studies; Respiratory Distress Syndrome; Steroids; Wounds and Injuries | 1985 |
Experimental posttraumatic pulmonary microembolism. Effects of methylprednisolone on its development.
Topics: Animals; Blood Platelets; Disease Models, Animal; Female; Fibrinogen; Lung; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Platelet Count; Pulmonary Embolism; Swine; Time Factors; Wounds and Injuries | 1985 |
Kinetics of methylprednisolone and its hemisuccinate ester.
Topics: Absorption; Administration, Oral; Adult; Biological Availability; Chromatography, High Pressure Liquid; Female; Half-Life; Humans; Injections, Intravenous; Kinetics; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Middle Aged; Saliva | 1985 |
Strategies in the design of solution-stable, water-soluble prodrugs III: influence of the pro-moiety on the bioconversion of 21-esters of corticosteroids.
Topics: Adrenal Cortex Hormones; Animals; Biological Availability; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Female; Half-Life; Humans; Hydrolysis; Kinetics; Macaca mulatta; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Solubility | 1985 |
High-dose methylprednisolone sodium succinate (pulse therapy) in the treatment of renal disease: plasma and urine concentrations.
Topics: Adult; Creatinine; Glomerulonephritis; Humans; Kidney Diseases; Kidney Transplantation; Methylprednisolone; Methylprednisolone Hemisuccinate; Middle Aged | 1985 |
Rapid response of intrasplenic lesions to steroids in non-Hodgkin's lymphoma.
Topics: Aged; Female; Gallium Radioisotopes; Humans; Lymphoma; Methylprednisolone; Methylprednisolone Hemisuccinate; Radionuclide Imaging; Splenic Neoplasms; Technetium Tc 99m Sulfur Colloid | 1985 |
Rapid method for the measurement of methylprednisolone and its hemisuccinate in plasma and urine following "pulse therapy" by high-performance liquid chromatography.
Topics: Acute Kidney Injury; Arthritis, Rheumatoid; Chromatography, High Pressure Liquid; Humans; Infusions, Parenteral; Kinetics; Methylprednisolone; Methylprednisolone Hemisuccinate | 1985 |
[A study of the optimum dose of a glucocorticoid, methylprednisolone sodium succinate, before and after neurosurgical major operations--relationship between beta-glucuronidase level and post operative brain edema].
Topics: Adolescent; Adult; Aged; Brain; Brain Edema; Craniotomy; Female; Glucocorticoids; Glucuronidase; Humans; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Middle Aged; Postoperative Complications; Preoperative Care | 1985 |
Potentiation of photodynamic therapy with haematoporphyrin derivatives by glucocorticoids.
Topics: Animals; Cell Line; Drug Interactions; Glucocorticoids; Hematoporphyrin Photoradiation; Hydrocortisone; Lung Neoplasms; Melanoma; Methylprednisolone; Methylprednisolone Acetate; Methylprednisolone Hemisuccinate; Mice; Mice, Inbred C57BL; Neoplasm Recurrence, Local; Photochemotherapy; Photosensitivity Disorders; Time Factors | 1985 |
A simplified method for the preparation of EAC14 intermediate cells using human serum treated with methylprednisolone.
Topics: Animals; Complement C1; Complement C4; Complement Inactivator Proteins; Complement Pathway, Classical; Complement System Proteins; Erythrocytes; Humans; Methylprednisolone; Methylprednisolone Hemisuccinate; Sheep | 1985 |
High-performance liquid chromatographic assay for methylprednisolone and its soluble prodrug esters in dog plasma.
Topics: Animals; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Dogs; Kinetics; Methylprednisolone; Methylprednisolone Hemisuccinate; Spectrophotometry, Ultraviolet | 1985 |
Posttraumatic respiratory distress syndrome and high-dose corticosteroids.
Topics: Animals; Drug Administration Schedule; Female; Fibrin; Fibrinogen; Hemodynamics; Lung; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Oxygen; Oxygen Consumption; Platelet Count; Pulmonary Embolism; Respiratory Distress Syndrome; Shock, Traumatic; Swine | 1985 |
Modulation of the proteolytic cascade systems by high dose corticosteroids.
Topics: alpha-2-Antiplasmin; Animals; Antithrombin III; Ascitic Fluid; Blood Coagulation Factors; Fibrinolysis; Hemodynamics; Humans; In Vitro Techniques; Kallikreins; Kinins; Methylprednisolone; Methylprednisolone Hemisuccinate; Pancreatitis; Plasminogen; Prekallikrein; Prothrombin; Swine; Trypsin | 1985 |
["Pulse" methylprednisolone therapy in children with idiopathic thrombocytopenic purpura].
Topics: Adolescent; Child; Child, Preschool; Drug Administration Schedule; Female; Humans; Infusions, Parenteral; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Platelet Count; Purpura, Thrombocytopenic | 1985 |
Metabolic and cardiovascular effects of endotoxin infusion in conscious unrestrained rats: effects of methylprednisolone and BW755C.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 6-Ketoprostaglandin F1 alpha; Animals; Antimetabolites; Arachidonic Acids; Blood Pressure; Heart Rate; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Pyrazoles; Rats; Rats, Inbred Strains; Shock, Septic; Thromboxane B2 | 1985 |
A dermatitis-eosinophilia syndrome. Treatment with methylprednisolone pulse therapy.
Topics: Adrenocorticotropic Hormone; Dermatitis; Eosinophilia; Humans; Hydrocortisone; Insect Bites and Stings; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Middle Aged; Skin; Syndrome; Triamcinolone Acetonide; Wasps | 1984 |
Allergic reactions--the roles of corticosteroids, ibuprofen, H2 antagonists.
Topics: Drug Hypersensitivity; Drug Interactions; Histamine H2 Antagonists; Humans; Ibuprofen; Methylprednisolone; Methylprednisolone Hemisuccinate | 1983 |
Relationship between cell ploidy and glucocorticoid induced death in human lymphoid cell lines.
Topics: Cell Line; Cell Survival; Clone Cells; DNA; Flow Cytometry; Humans; Kinetics; Lymphocytes; Methylprednisolone; Methylprednisolone Hemisuccinate; Ploidies; Staining and Labeling; Time Factors | 1984 |
[Plasma assays in bolus injections of methylprednisolone in children].
Topics: Adolescent; Child; Child, Preschool; Humans; Methylprednisolone; Methylprednisolone Hemisuccinate | 1984 |
Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation.
Topics: Animals; Chromatin; Deoxyribonucleases; Endonucleases; Methylprednisolone; Methylprednisolone Hemisuccinate; Molecular Weight; Nucleosomes; Rats; Thymus Gland | 1980 |
Correlation of methylprednisolone levels in cat spinal cord with its effects on (Na+ + K+)-ATPase, lipid peroxidation, and alpha motor neuron function.
Topics: Animals; Cats; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Lipid Peroxides; Male; Malondialdehyde; Membrane Potentials; Methylprednisolone; Methylprednisolone Hemisuccinate; Motor Neurons; Sodium-Potassium-Exchanging ATPase; Spinal Cord; Spinal Cord Injuries | 1982 |
Effects of intravenous methylprednisolone on spinal cord lipid peroxidation and Na+ + K+)-ATPase activity. Dose-response analysis during 1st hour after contusion injury in the cat.
Topics: Animals; Blood Pressure; Cats; Cyclic GMP; Dose-Response Relationship, Drug; Female; Free Radicals; Injections, Intravenous; Lipid Peroxides; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Sodium-Potassium-Exchanging ATPase; Spinal Cord Injuries; Time Factors | 1982 |
Neutrophil response to LIF: lack of glucocorticoid effect despite enhanced chemokinesis.
Topics: Arachidonic Acid; Arachidonic Acids; Chemotaxis, Leukocyte; Humans; Inflammation; Leukocyte Migration-Inhibitory Factors; Leukotriene B4; Lymphokines; Methylprednisolone; Methylprednisolone Hemisuccinate; Neutrophils; Phytohemagglutinins | 1983 |
Modification of airway histamine-receptor function with methylprednisolone succinate.
Topics: Animals; Chlorpheniramine; Female; Histamine; Lung; Methylprednisolone; Methylprednisolone Hemisuccinate; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Respiratory Physiological Phenomena; Respiratory System; Sheep | 1983 |
Uptake and elimination of methylprednisolone from contused cat spinal cord following intravenous injection of the sodium succinate ester.
Topics: Animals; Cats; Contusions; Female; Injections, Intravenous; Kinetics; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Spinal Cord; Spinal Cord Injuries | 1983 |
Mode of cell death induced in human lymphoid cells by high and low doses of glucocorticoid.
Topics: Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance; Fibroblasts; Humans; Leukemia, Lymphoid; Lymphocytes; Methylprednisolone; Methylprednisolone Hemisuccinate; Microscopy, Electron; Steroids; Time Factors | 1983 |
Relationship of serum gentamicin levels and methylprednisolone sodium succinate treatment in baboons challenged with Escherichia coli LD100.
Topics: Animals; Drug Therapy, Combination; Escherichia coli Infections; Gentamicins; Methylprednisolone; Methylprednisolone Hemisuccinate; Papio | 1983 |
Modeling cortical cataractogenesis. V. Steroid cataracts induced by solumedrol partially prevented by vitamin E in vitro.
Topics: Animals; Cataract; Dose-Response Relationship, Drug; In Vitro Techniques; Lens Cortex, Crystalline; Lens, Crystalline; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Microscopy, Electron, Scanning; Rats; Rats, Inbred Strains; Vitamin E | 1983 |
The benefits of corticosteroid given after the onset of hypotension during endotoxin shock in the conscious rat.
Topics: Animals; Blood Gas Analysis; Blood Pressure; Gastrointestinal Hemorrhage; Heart Rate; Hypotension; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Rats; Rats, Inbred Strains; Respiration; Shock, Septic; Time Factors | 1983 |
Prevention or amelioration of morphologic lesions in LD100 E coli-shocked baboons with steroid/antibiotic therapy.
Topics: Adrenal Glands; Animals; Digestive System; Drug Therapy, Combination; Gentamicins; Kidney; Liver; Lung; Methylprednisolone; Methylprednisolone Hemisuccinate; Papio; Shock, Septic; Spleen | 1983 |
Stability of methylprednisolone sodium succinate in 5% dextrose and 0.9% sodium chloride injections.
Topics: Chromatography, High Pressure Liquid; Drug Stability; Glucose; Hydrogen-Ion Concentration; Methylprednisolone; Methylprednisolone Hemisuccinate; Nephelometry and Turbidimetry; Sodium Chloride; Time Factors | 1983 |
The injection-adjustable mammary implant.
Topics: Breast; Contracture; Female; Humans; Methylprednisolone; Methylprednisolone Hemisuccinate; Patient Compliance; Prostheses and Implants; Sodium Chloride | 1983 |
Effects of methylprednisolone on resolution of acid-aspiration pneumonitis.
Topics: Animals; Dogs; Gastric Acid; Lung; Methylprednisolone; Methylprednisolone Hemisuccinate; Pneumonia, Aspiration; Time Factors | 1983 |
Effectiveness of modified steroid-antibiotic therapies for lethal sepsis in the dog.
Topics: Animals; Blood Pressure; Dogs; Drug Evaluation; Drug Therapy, Combination; Escherichia coli Infections; Female; Gentamicins; Heart Rate; Infusions, Parenteral; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Netilmicin; Shock, Septic; Time Factors | 1983 |
[Methylprednisolone sodium succinate in acute myocardial infarct].
Topics: Adult; Aged; Drug Evaluation; Female; Humans; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Middle Aged; Myocardial Infarction | 1983 |
Analysis of cortisol, methylprednisolone, and methylprednisolone hemisuccinate. Absence of effects of troleandomycin on ester hydrolysis.
Topics: Adult; Child; Female; Humans; Hydrocortisone; Hydrolysis; Kinetics; Liver; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Troleandomycin | 1984 |
Inhibition of antigen-induced bronchoconstriction by methylprednisolone succinate.
Topics: Animals; Antigens; Ascaris; Bronchi; Constriction, Pathologic; Female; Methylprednisolone; Methylprednisolone Hemisuccinate; Respiratory Hypersensitivity; Sheep; Time Factors | 1984 |
Effects of a single large dose of methylprednisolone sodium succinate on experimental posttraumatic spinal cord ischemia. Dose-response and time-action analysis.
Topics: Animals; Cats; Female; Ischemia; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Spinal Cord; Spinal Cord Injuries | 1984 |
Carboxyl group catalysis of acyl transfer reactions in corticosteroid 17- and 21-monoesters.
Topics: Adrenal Cortex Hormones; Catalysis; Chemical Phenomena; Chemistry, Physical; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Methylprednisolone; Methylprednisolone Acetate; Methylprednisolone Hemisuccinate; Water | 1984 |
Effects of steroid treatment on release of cardiac myosin light chain II in acute myocardial infarction in dogs.
Topics: Acetylglucosaminidase; Animals; Creatine Kinase; Dogs; Methylprednisolone; Methylprednisolone Hemisuccinate; Myocardial Infarction; Myocardium; Myosins | 1984 |
Corticosteroids in the treatment of blunt injury of the chest.
Topics: Adult; Female; Hemodynamics; Humans; Lung; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Middle Aged; Oxygen Consumption; Prospective Studies; Pulmonary Gas Exchange; Thoracic Injuries; Vascular Resistance; Wounds, Nonpenetrating | 1984 |
Methylprednisolone.
Topics: Animals; Dogs; Humans; Methylprednisolone; Methylprednisolone Hemisuccinate; Vasoconstriction | 1984 |
Effect of high-dose methylprednisolone therapy on phagocyte function in systemic lupus erythematosus.
Topics: Adult; Cell Count; Cell Movement; Female; Humans; Lactoferrin; Lupus Erythematosus, Systemic; Methylprednisolone; Methylprednisolone Hemisuccinate; Middle Aged; Neutrophils; Phagocytes; Phagocytosis; Staphylococcus aureus; Streptococcus pneumoniae; Time Factors | 1984 |
Effect of methylprednisolone and "pulse" therapy with methylprednisolone sodium succinate on autologous immune complex nephritis in rats.
Topics: Animals; Blood Proteins; Immune Complex Diseases; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Nephritis; Proteinuria; Rats; Time Factors | 1980 |
Rate of diffusion of Solu-Medrol across the silastic membranes of breast prostheses-an in vitro study.
Topics: Breast; Diffusion; Female; Humans; In Vitro Techniques; Methylprednisolone; Methylprednisolone Hemisuccinate; Postoperative Complications; Prostheses and Implants; Silicone Elastomers; Steroids | 1982 |
Methylprednisolone inhibits the alternative and amplification pathways of complement.
Topics: Complement Activation; Complement C3b; Complement Factor B; Complement Factor D; Complement Pathway, Alternative; Enzyme Precursors; Humans; Lipopolysaccharides; Methylprednisolone; Methylprednisolone Hemisuccinate; Zymosan | 1982 |
Current management of the septic shock patient: experimental basis for treatment.
Topics: Animals; Blood Glucose; Dogs; Drug Therapy, Combination; Endotoxins; Escherichia coli; Gentamicins; Hemodynamics; Infusions, Parenteral; Insulin; Methylprednisolone; Methylprednisolone Hemisuccinate; Papio; Shock, Septic | 1982 |
[Aneurysmatic evolution of myocardial infarct treated in the acute phase with methylprednisolone. Angiocardioscintigraphic evaluation].
Topics: Adult; Aged; Angiocardiography; Female; Heart; Heart Aneurysm; Humans; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Middle Aged; Myocardial Infarction; Radionuclide Imaging | 1982 |
[Prevention of pulmonary structural changes in experimental peritonitis].
Topics: Animals; Female; Intestinal Perforation; Lung; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Peritonitis; Rats; Rats, Inbred Strains; Respiratory Distress Syndrome; Salicylates | 1982 |
[Evaluation of the effectiveness of methylprednisolone sodium succinate in reducing the infarct area].
Topics: Adult; Aged; Creatine Kinase; Drug Evaluation; Female; Follow-Up Studies; Hemodynamics; Humans; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Middle Aged; Myocardial Infarction | 1981 |
Cadaver kidney transplantation: a retrospective comparison of two immunosuppressive regimens.
Topics: Adult; Antilymphocyte Serum; Azathioprine; Cadaver; Drug Therapy, Combination; Female; Graft Survival; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Middle Aged; Prednisone; Retrospective Studies | 1982 |
Survival of primates in LD100 septic shock following steroid/antibiotic therapy.
Topics: Acid-Base Equilibrium; Animals; Anuria; Blood Cell Count; Blood Glucose; Blood Urea Nitrogen; Bone Marrow; Creatinine; Drug Therapy, Combination; Escherichia coli Infections; Female; Gentamicins; Haplorhini; Hemodynamics; Insulin; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Papio; Shock, Septic | 1980 |
Hydrolysis of methylprednisolone hemisuccinate to methylprednisolone by a nonspecific carboxylesterase.
Topics: Animals; Carboxylic Ester Hydrolases; Dogs; Female; Hydrolysis; In Vitro Techniques; Kinetics; Liver; Methylprednisolone; Methylprednisolone Hemisuccinate; Substrate Specificity; Swine | 1980 |
The effect of methylprednisolone sodium succinate on erythrocyte and haemoglobin function.
Topics: Cells, Cultured; Diphosphoglyceric Acids; Dose-Response Relationship, Drug; Erythrocytes; Hemoglobins; Humans; Hydrogen-Ion Concentration; Methylprednisolone; Methylprednisolone Hemisuccinate; Oxygen; Partial Pressure; Sodium Chloride | 1980 |
Acute hemolytic anemia secondary to infectious mononucleosis.
Topics: Adult; Anemia, Hemolytic; Humans; Infectious Mononucleosis; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Prednisone | 1980 |
Hypoxia of canine gastric mucosa caused by Escherichia coli sepsis and prevented with methylprednisolone therapy.
Topics: Animals; Dogs; Escherichia coli Infections; Female; Gastric Mucosa; Hemodynamics; Hypoxia; Male; Membrane Potentials; Methylprednisolone; Methylprednisolone Hemisuccinate; Microcirculation; Oxygen; Sepsis | 1981 |
Effects of corticosteroids on eosinophil chemotaxis and adherence.
Topics: Cell Adhesion; Chemotaxis, Leukocyte; Dose-Response Relationship, Drug; Eosinophils; Humans; Hydrocortisone; Methylprednisolone; Methylprednisolone Hemisuccinate; Prednisone | 1981 |
Anaphylaxis after intravenous methylprednisolone administration.
Topics: Adult; Anaphylaxis; Bronchial Spasm; Drug Hypersensitivity; Humans; Injections, Intravenous; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Skin Tests | 1981 |
Reappearance of Sporothrix schenckii lesions after administration of Solu-Medrol R to infected cats.
Topics: Animals; Cats; Disease Models, Animal; Female; Immunity; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Sporothrix; Sporotrichosis | 1980 |
Corticosteroid therapy in hemorrhagic and septic shock in puppies.
Topics: Acid Phosphatase; Animals; Disease Models, Animal; Dogs; Escherichia coli; Fatty Acids, Nonesterified; Glucose; Hemodynamics; Lactates; Methylprednisolone; Methylprednisolone Hemisuccinate; Shock, Hemorrhagic; Shock, Septic; Triglycerides | 1980 |
Initial rate studies of hydrolysis and acyl migration in methylprednisolone 21-hemisuccinate and 17-hemisuccinate.
Topics: Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Hydrolysis; Isomerism; Kinetics; Methylprednisolone; Methylprednisolone Hemisuccinate; Temperature | 1981 |
Influence of 6 alpha-methylprednisolone 21-sodium succinate on the pituitary, adrenal glands, and the gastrointestinal tract in rats. (Comparative toxicity study with hydrocortisone 21-sodium succinate).
Topics: Adrenal Glands; Animals; Corticosterone; Digestive System; Hydrocortisone; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Organ Size; Pituitary Gland; Rats | 1980 |
[Liver zinc uptake, influence of glucocorticoids and its chronology (author's transl)].
Topics: Animals; Biological Transport; Female; Glucocorticoids; Liver; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Rats; Time Factors; Zinc | 1980 |
High dose intravenous methyl prednisolone (pulse therapy) in the treatment of rheumatoid disease.
Topics: Adult; Aged; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Humans; Infusions, Parenteral; Methylprednisolone; Methylprednisolone Hemisuccinate; Middle Aged | 1981 |
Survival of primates in lethal septic shock following delayed treatment with steroid.
Topics: Animals; Drug Therapy, Combination; Female; Gentamicins; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Papio; Shock, Septic; Time Factors | 1981 |
Effects of methylprednisolone and azathioprine on bronchial healing following lung autotransplantation.
Topics: Animals; Azathioprine; Bronchi; Dogs; Lung Transplantation; Methylprednisolone; Methylprednisolone Hemisuccinate; Skin; Tensile Strength; Time Factors; Transplantation, Autologous; Wound Healing | 1981 |
Placental transfer of methylprednisolone following maternal intravenous administration.
Topics: Female; Humans; Injections, Intravenous; Maternal-Fetal Exchange; Methylprednisolone; Methylprednisolone Hemisuccinate; Pregnancy; Radioimmunoassay | 1981 |
Stability of methylprednisolone sodium succinate in small volumes of 5% dextrose and 0.9% sodium chloride injections.
Topics: Drug Packaging; Drug Stability; Glucose; Hydrogen-Ion Concentration; Injections; Methylprednisolone; Methylprednisolone Hemisuccinate; Nephelometry and Turbidimetry; Sodium Chloride | 1981 |
Influence of methylprednisolone on reticuloendothelial phagocytic and opsonic function during traumatic and septic shock.
Topics: Animals; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Mononuclear Phagocyte System; Opsonin Proteins; Phagocytosis; Rats; Rats, Inbred Strains; Shock, Septic; Shock, Traumatic | 1980 |
Successful renal transplantation in a patient with anaphylactic reaction to Solu-Medrol (methylprednisolone sodium succinate).
Topics: Adult; Anaphylaxis; Azathioprine; Dexamethasone; Humans; Kidney Failure, Chronic; Kidney Transplantation; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Skin Tests | 1982 |
Bone growth in the rat mandible following every-day or alternate-day methylprednisolone treatment schedules.
Topics: Animals; Circadian Rhythm; Drug Administration Schedule; Male; Mandible; Methylprednisolone; Methylprednisolone Hemisuccinate; Rats; Rats, Inbred Strains | 1981 |
Prevention of aconitine-induced neurogenic pulmonary edema (NPE) with hypovolemia or methylprednisolone.
Topics: Aconitine; Aconitum; Animals; Blood Pressure; Blood Volume; Female; Lung; Methylprednisolone; Methylprednisolone Hemisuccinate; Pulmonary Edema; Rats | 1982 |
Late side effects related to inflatable breast prostheses containing soluble steroids.
Topics: Atrophy; Breast; Contracture; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Isomerism; Methylprednisolone; Methylprednisolone Hemisuccinate; Prolapse; Prostheses and Implants; Surgery, Plastic | 1982 |
High dose intravenous methylprednisolone "pulse" therapy in patients with rheumatoid disease. Plasma methylprednisolone levels and adrenal function.
Topics: Adult; Aged; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Female; Humans; Hydrocortisone; Infusions, Parenteral; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Middle Aged; Radioimmunoassay | 1982 |
Influence of the salt moiety on the effectiveness of corticosteroid therapy in cardiogenic shock.
Topics: Adrenal Cortex Hormones; Animals; Dogs; Drug Synergism; Methylprednisolone; Methylprednisolone Hemisuccinate; Phosphates; Shock, Cardiogenic; Sodium; Succinates; Succinic Acid | 1982 |
Immediate inhibitory effect of methylprednisolone suleptanate (U-67590A) on antigen-induced cutaneous and airway anaphylactic responses in guinea-pigs.
Topics: Airway Resistance; Anaphylaxis; Animals; Bradykinin; Capillary Permeability; Cycloheximide; Dexamethasone; Guinea Pigs; Histamine; Histamine Release; Immunoglobulin E; Immunoglobulin G; In Vitro Techniques; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Passive Cutaneous Anaphylaxis; Receptors, Glucocorticoid; Respiratory System; Skin | 1993 |
[Pulmonary lesions after inhalation of nitrous vapors].
Topics: Bronchiolitis Obliterans; Humans; Inhalation; Lung; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Middle Aged; Nitric Acid; Pulmonary Fibrosis; Spiramycin | 1994 |
Pharmacokinetics of methylprednisolone hemisuccinate and methylprednisolone in chronic liver disease.
Topics: Adult; Chronic Disease; Half-Life; Humans; Hydrocortisone; Hypertension, Portal; Liver Cirrhosis, Alcoholic; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Middle Aged | 1993 |
The perioperative use of corticosteroids and bupivacaine in the management of lumbar disc disease.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Bupivacaine; Drug Therapy, Combination; Humans; Intervertebral Disc Displacement; Intraoperative Period; Low Back Pain; Methylprednisolone; Methylprednisolone Acetate; Methylprednisolone Hemisuccinate; Middle Aged; Pain, Postoperative | 1993 |
High-performance liquid chromatography separation and quantitation of methylprednisolone from rat brain.
Topics: Animals; Brain Chemistry; Cerebral Cortex; Chromatography, High Pressure Liquid; Female; Injections, Intra-Arterial; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Rats; Rats, Sprague-Dawley; Rats, Wistar | 1993 |
Histologic changes in the intervertebral disc after intradiscal injections of methylprednisolone acetate in rabbits.
Topics: Animals; Anti-Inflammatory Agents; Calcinosis; Injections, Spinal; Intervertebral Disc; Lumbar Vertebrae; Male; Methylprednisolone; Methylprednisolone Acetate; Methylprednisolone Hemisuccinate; Microscopy, Electron; Rabbits; Spinal Diseases | 1997 |
Long-term follow-up of platinum-based lymphoma salvage regimens. The M.D. Anderson Cancer Center experience.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cytarabine; Dexamethasone; Disease-Free Survival; Etoposide; Follow-Up Studies; Humans; Ifosfamide; Life Tables; Lymphoma, Non-Hodgkin; Mesna; Methylprednisolone; Methylprednisolone Hemisuccinate; Mitoxantrone; Prognosis; Salvage Therapy; Texas; Treatment Outcome | 1997 |
Simultaneous analysis of dextran-methylprednisolone succinate, methylprednisolone succinate, and methylprednisolone by size-exclusion chromatography.
Topics: Anti-Inflammatory Agents; Calibration; Chromatography, Gel; Dextrans; Drug Stability; Hydrogen-Ion Concentration; Methylprednisolone; Methylprednisolone Hemisuccinate; Molecular Weight; Reproducibility of Results; Solutions | 1999 |
Simultaneous analysis of methylprednisolone, methylprednisolone succinate, and endogenous corticosterone in rat plasma.
Topics: Albumins; Animals; Anti-Inflammatory Agents; Calibration; Chromatography, High Pressure Liquid; Corticosterone; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Rats; Rats, Sprague-Dawley; Reference Standards; Reproducibility of Results | 2000 |
[Trial of 6-methylprednisolone sodium hemisuccinate (Solumedrol) by the intravenous route in the treatment of malignant blood diseases in adults].
Topics: Hematologic Diseases; Humans; Injections, Intravenous; Methylphenidate; Methylprednisolone; Methylprednisolone Hemisuccinate; Sodium | 1962 |
[Thin-layer chromatography studies on the metabolism of prednisolone-Na-hemisuccinate and 6-alpha-methylprednisolone-Na-hemisuccinate].
Topics: Chromatography, Thin Layer; Methylprednisolone; Methylprednisolone Hemisuccinate; Prednisolone; Sodium | 1962 |
[Value of methyl-6-prednisolone sodium hemisuccinate (Solumedrol) in the treatment of malignant tumors].
Topics: Humans; Methylprednisolone; Methylprednisolone Hemisuccinate; Neoplasms; Prednisolone; Sodium; Sodium, Dietary | 1962 |
METHYLPREDNISOLONE SODIUM SUCCINATE IN ACUTE CRANIOCEREBRAL TRAUMA.
Topics: Brain Injuries; Craniocerebral Trauma; Decerebrate State; Drug Therapy; Hematoma; Hematoma, Epidural, Cranial; Hematoma, Subdural; Humans; Methylprednisolone; Methylprednisolone Hemisuccinate; Mortality; Prognosis; Toxicology | 1965 |
Population pharmacokinetics of methylprednisolone in accident victims with spinal cord injury.
Topics: Accidents; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Area Under Curve; Chromatography, High Pressure Liquid; Female; Humans; Infusions, Intravenous; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Middle Aged; Saliva; Spinal Cord Injuries | 2004 |
Steroids protect the beta-adrenergic system during reperfusion after ischemia: effects of methylprednisolone on the beta-adrenergic response system.
Topics: Adenylyl Cyclases; Animals; Cyclic AMP; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Myocardial Reperfusion Injury; Rats; Rats, Wistar; Receptors, Adrenergic, beta | 1988 |
Caution: all "medrols" are not the same.
Topics: Adrenal Cortex Hormones; Child; Child, Preschool; Drug Compounding; Drug Dosage Calculations; Humans; Infusions, Intravenous; Injections, Intramuscular; Medication Errors; Methylprednisolone; Methylprednisolone Acetate; Methylprednisolone Hemisuccinate | 2009 |
Intra-arterial injection in the rat brain: evaluation of steroids used for transforaminal epidurals.
Topics: Analgesia, Epidural; Animals; Blood-Brain Barrier; Brain; Carotid Artery, External; Central Nervous System Diseases; Dexamethasone; Drug Carriers; Injections, Epidural; Injections, Intra-Arterial; Methylprednisolone; Methylprednisolone Acetate; Methylprednisolone Hemisuccinate; Models, Animal; Rats; Rats, Wistar; Sodium Chloride; Steroids | 2009 |
Which regimen is better for stem cell mobilization of lymphoma patients?
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Cytarabine; Deoxycytidine; Doxorubicin; Female; Gemcitabine; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Humans; Lymphoma; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Middle Aged; Procarbazine; Retrospective Studies; Salvage Therapy; Treatment Outcome; Vinblastine; Vinorelbine | 2013 |
Anaphylactic shock with methylprednisolone, Kounis syndrome and hypersensitivity to corticosteroids: a clinical paradox.
Topics: Adrenal Cortex Hormones; Anaphylaxis; Animals; Cattle; Child; Female; Humans; Hypersensitivity; Methylprednisolone; Methylprednisolone Hemisuccinate; Milk Hypersensitivity; Short Bowel Syndrome | 2018 |
Methylprednisolone-Induced Hypersensitivity Reaction in a Liver Transplant Recipient.
Topics: Dexamethasone; Female; Humans; Hypersensitivity; Liver Transplantation; Methylprednisolone; Methylprednisolone Hemisuccinate; Prednisone; Treatment Outcome | 2022 |
Effectiveness of gamma globulin combined with methylprednisolone sodium succinate in severe hand foot mouth disease - Baoding Children's Hospital, China.
Topics: Case-Control Studies; Child; China; gamma-Globulins; Hand, Foot and Mouth Disease; Hospitals; Humans; Methylprednisolone; Methylprednisolone Hemisuccinate; Mouth Diseases | 2020 |
Postauricular injection of methylprednisolone sodium succinate as a salvage treatment for refractory sudden sensorineural hearing loss.
Topics: Dexamethasone; Glucocorticoids; Hearing Loss, Sensorineural; Humans; Methylprednisolone; Methylprednisolone Hemisuccinate; Retrospective Studies; Salvage Therapy; Treatment Outcome | 2021 |
Microneedle/CD-MOF-mediated transdural controlled release of methylprednisolone sodium succinate after spinal cord injury.
Topics: Animals; beta-Cyclodextrins; Cyclodextrins; Delayed-Action Preparations; Metal-Organic Frameworks; Methylprednisolone; Methylprednisolone Hemisuccinate; Spinal Cord; Spinal Cord Injuries | 2023 |
A new validated facile HPLC analysis method to determine methylprednisolone including its derivatives and practical application.
Topics: Anti-Inflammatory Agents; Chromatography, High Pressure Liquid; Egypt; Methylprednisolone; Methylprednisolone Hemisuccinate | 2023 |