methylprednisolone and verapamil

methylprednisolone has been researched along with verapamil in 40 studies

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19906 (15.00)18.7374
1990's3 (7.50)18.2507
2000's18 (45.00)29.6817
2010's13 (32.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Thakker, DR; Troutman, MD1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Chen, X; Lin, X; Skolnik, S; Wang, J1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Fassold, E; Nayler, WG; Yepez, C1
Bake, I; Buttazzoni, E; Csongrady, A; Pfänder, C; Schneider, M; Tarmann, H1
Kuznetsov, SI; Provotorov, VM2
Armstrong, J; Dawidson, I; Diller, K; Lafferty, K; Pratt, P; Rooth, P; Simonsen, R; Täljedal, IB1
Bell, JB; Gore, ME; Maitland, JA; McElwain, TJ; Millar, BC; Selby, PJ; Zuiable, A1
Bruserud, O; Jørgensen, PF; Sollid, L1
Andersen, K; Arnbjerg, J; Fischer Hansen, B; Husum, B; Vejlsted, H1
Fujimura, H; Nishiyama, S; Ohmachi, Y; Okumura, F; Toriumi, W; Yoneda, H1
Erfurth, A; Evers, S; Frese, A; Husstedt, IW; Lüttmann, RJ1
Aungst, BJ; Nakayama, A; Oda, M; Oka, A; Saitoh, H; Takada, M1
Dommerich, S; Graumüller, S; Hoff, M; Ostwald, J1
Alberca, R; Cayuela, A; Franco, E; Lozano, P; Martínez, E; Mir, P; Montes, E; Navarro, A1
Moyssakis, I; Papadopoulos, DP; Votteas, VE1
Baskiewicz-Masiuk, M; Gawronska-Szklarz, B; Machalinski, B; Pawlik, A1
Achiwa, K; Aungst, BJ; Kobayashi, M; Oda, M; Saikachi, Y; Saitoh, H; Tadano, K; Takahashi, Y; Yamaguchi, M; Yuhki, Y1
Riederer, F; Sándor, PS; Selekler, HM; Wöber, C1
Bleck, TP; Fletcher, JJ; Kramer, AH; Solenski, NJ1
Asghar, SJ; Glasier, C; Kaushik, C; Milesi-Hallé, A; Sharp, GB1
Shimizu, T1
Hsiao, YC; Yang, JY; Yang, SY1

Reviews

2 review(s) available for methylprednisolone and verapamil

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[New treatments for cluster headache].
    Rinsho shinkeigaku = Clinical neurology, 2013, Volume: 53, Issue:11

    Topics: Administration, Intranasal; Calcium Channel Blockers; Cluster Headache; Deep Brain Stimulation; Dexamethasone; Humans; Injections, Subcutaneous; Methylprednisolone; Nerve Block; Oxazolidinones; Oxygen Inhalation Therapy; Sumatriptan; Tryptamines; Vagus Nerve Stimulation; Verapamil

2013

Trials

2 trial(s) available for methylprednisolone and verapamil

ArticleYear
[Treatment of bronchial asthma by intrapulmonary administration of steroid hormones and calcium antagonists].
    Sovetskaia meditsina, 1990, Issue:11

    Topics: Adult; Asthma; Bronchodilator Agents; Calcium Channel Blockers; Female; Glucocorticoids; Humans; Male; Methylprednisolone; Middle Aged; Verapamil

1990
Prophylactic treatment of episodic cluster headache with intravenous bolus of methylprednisolone.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2003, Volume: 24, Issue:5

    Topics: Adult; Cluster Headache; Drug Administration Schedule; Drug Therapy, Combination; Ergotamine; Humans; Injections, Intravenous; Male; Methylprednisolone; Middle Aged; Prednisone; Secondary Prevention; Sumatriptan; Treatment Outcome; Verapamil

2003

Other Studies

36 other study(ies) available for methylprednisolone and verapamil

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Novel experimental parameters to quantify the modulation of absorptive and secretory transport of compounds by P-glycoprotein in cell culture models of intestinal epithelium.
    Pharmaceutical research, 2003, Volume: 20, Issue:8

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blotting, Western; Cells, Cultured; Diffusion; Humans; Intestinal Absorption; Intestinal Mucosa; Models, Biological; Permeability; Pharmaceutical Preparations; Pharmacokinetics

2003
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Pharmacological protection of mitochondrial function in hypoxic heart muscle: Effect of verapamil, propranolol, and methylprednisolone.
    Cardiovascular research, 1978, Volume: 12, Issue:3

    Topics: Animals; Calcium; Hypoxia; In Vitro Techniques; Male; Methylprednisolone; Mitochondria, Heart; Oxidative Phosphorylation; Propranolol; Rabbits; Verapamil

1978
[A further case of malignant hyperpyrexia and its treatment with lidocaine, methylprednisolone and verapamil (iproveratril) (author's transl)].
    Der Anaesthesist, 1976, Volume: 25, Issue:2

    Topics: Acidosis; Adult; Calcium; Cryotherapy; Glucose; Halothane; Humans; Insulin; Lidocaine; Male; Malignant Hyperthermia; Methylprednisolone; Muscle Relaxants, Central; Oxygen; Succinylcholine; Verapamil

1976
[The treatment of bronchial asthma patients with intrapulmonary injections of metipred and finoptin using a needle jet injector].
    Vrachebnoe delo, 1990, Issue:3

    Topics: Adult; Asthma; Bronchodilator Agents; Female; Glucocorticoids; Humans; Injections, Intralesional; Injections, Intramuscular; Injections, Intravenous; Injections, Jet; Lung; Male; Methylprednisolone; Middle Aged; Verapamil

1990
Prevention of detrimental effect of cyclosporin A on vascular ingrowth of transplanted pancreatic islets with verapamil.
    Diabetes, 1989, Volume: 38 Suppl 1

    Topics: Animals; Cyclosporins; Islets of Langerhans; Male; Methylprednisolone; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence; Verapamil

1989
In vitro studies of ways to overcome resistance to VAMP--high dose melphalan in the treatment of multiple myeloma.
    British journal of haematology, 1989, Volume: 71, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cell Survival; Colony-Forming Units Assay; Daunorubicin; Doxorubicin; Drug Resistance; Humans; Melphalan; Methylprednisolone; Multiple Myeloma; Tumor Cells, Cultured; Tumor Stem Cell Assay; Verapamil; Vincristine

1989
The proliferative T-lymphocyte response to streptokinase.
    Journal of clinical & laboratory immunology, 1986, Volume: 20, Issue:2

    Topics: Adult; Aminophylline; Antibody-Dependent Cell Cytotoxicity; Cells, Cultured; Cyclosporins; Dose-Response Relationship, Drug; Fetal Blood; Humans; Infant, Newborn; Kinetics; Lymphocyte Activation; Methylprednisolone; Streptokinase; T-Lymphocytes; T-Lymphocytes, Regulatory; Verapamil

1986
Myocardial preservation during anoxic arrest. Premedication with propranolol, verapamil or methylprednisolone.
    Scandinavian journal of thoracic and cardiovascular surgery, 1983, Volume: 17, Issue:3

    Topics: Animals; Constriction; Dogs; Electric Stimulation; Electrocardiography; Heart; Heart Arrest, Induced; Methylprednisolone; Myocardial Contraction; Premedication; Propranolol; Ventricular Fibrillation; Verapamil

1983
Involvement of angiotensin II in development of spontaneous nephrosis in Dahl salt-sensitive rats.
    European journal of pharmacology, 1998, Dec-04, Volume: 362, Issue:2-3

    Topics: Aging; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Body Weight; Calcium Channel Blockers; Cholesterol; Glucocorticoids; Hypertension; Imidazoles; Imidazolidines; Losartan; Male; Methylprednisolone; Nephrosis; Proteinuria; Rats; Rats, Inbred Dahl; Sodium Chloride, Dietary; Verapamil

1998
Corticosteroid-induced acute mania during a cluster headache episode.
    Cephalalgia : an international journal of headache, 2001, Volume: 21, Issue:8

    Topics: Acute Disease; Adolescent; Age of Onset; Antimanic Agents; Bipolar Disorder; Cluster Headache; Glucocorticoids; Humans; Male; Methylprednisolone; Middle Aged; Valproic Acid; Vasodilator Agents; Verapamil

2001
Secretory transport of methylprednisolone possibly mediated by P-glycoprotein in Caco-2 cells.
    Biological & pharmaceutical bulletin, 2002, Volume: 25, Issue:3

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Cell Membrane Permeability; Humans; Methylprednisolone; Verapamil

2002
[Influence of rhinologic usual and unusual drugs on fibroblasts from nasal polyps in cell culture].
    Laryngo- rhino- otologie, 2003, Volume: 82, Issue:6

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Androstadienes; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Beclomethasone; Calcium Channel Blockers; Cells, Cultured; Culture Media; Diclofenac; Fibroblasts; Fluticasone; Glucocorticoids; Hematologic Agents; Humans; In Vitro Techniques; Mesalamine; Methylprednisolone; Mometasone Furoate; Muscarinic Agonists; Nasal Polyps; Pentoxifylline; Pilocarpine; Piroxicam; Prednisolone; Pregnadienediols; Time Factors; Timolol; Verapamil

2003
Polyarteritis nodosa and hypertrophic obstructive cardiomyopathy. A true association?
    Clinical rheumatology, 2004, Volume: 23, Issue:1

    Topics: Amiodarone; Anti-Arrhythmia Agents; Cardiomyopathy, Hypertrophic; Cyclophosphamide; Drug Therapy, Combination; Echocardiography; Humans; Immunosuppressive Agents; Male; Methylprednisolone; Middle Aged; Polyarteritis Nodosa; Treatment Outcome; Verapamil

2004
Involvement of P-gp in the process of apoptosis in peripheral blood mononuclear cells.
    International immunopharmacology, 2005, Volume: 5, Issue:5

    Topics: Adult; Antibodies, Monoclonal; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cortisone; Dexamethasone; Female; Humans; In Vitro Techniques; Leukocytes, Mononuclear; Male; Methotrexate; Methylprednisolone; Middle Aged; Phytohemagglutinins; Verapamil

2005
Limited interaction between tacrolimus and P-glycoprotein in the rat small intestine.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2006, Volume: 28, Issue:1-2

    Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Cardiotonic Agents; Cyclosporine; Digoxin; Immunosuppressive Agents; Intestinal Absorption; Intestine, Small; Jejunum; Methylprednisolone; Progesterone; Rats; Tacrolimus; Verapamil; Vinblastine

2006
Cutaneous allodynia during cluster headache attacks.
    Cephalalgia : an international journal of headache, 2009, Volume: 29, Issue:7

    Topics: Adult; Anti-Inflammatory Agents; Cluster Headache; Female; Functional Laterality; Humans; Hyperesthesia; Male; Methylprednisolone; Middle Aged; Skin; Vasodilator Agents; Verapamil

2009
Overlapping features of eclampsia and postpartum angiopathy.
    Neurocritical care, 2009, Volume: 11, Issue:2

    Topics: Adult; Cerebrovascular Disorders; Eclampsia; Female; Headache; Humans; Methylprednisolone; Nicardipine; Postpartum Period; Pregnancy; Puerperal Disorders; Retrospective Studies; Seizures; Stroke; Subarachnoid Hemorrhage; Vasoconstriction; Vasodilator Agents; Verapamil; Young Adult

2009
Variable manifestations of familial hemiplegic migraine associated with reversible cerebral edema in children.
    Pediatric neurology, 2012, Volume: 47, Issue:3

    Topics: Adolescent; Anti-Inflammatory Agents; Brain Edema; Calcium Channel Blockers; Calcium Channels; Child; Cognition Disorders; DNA; Electroencephalography; Female; Functional Laterality; Gait Disorders, Neurologic; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Methylprednisolone; Migraine with Aura; Neurologic Examination; Sodium-Potassium-Exchanging ATPase; Verapamil

2012
Comparison of combination therapy (steroid, calcium channel blocker, and interferon) with steroid monotherapy for treating human hypertrophic scars in an animal model.
    Annals of plastic surgery, 2015, Volume: 74 Suppl 2

    Topics: Adult; Animals; Calcium Channel Blockers; Cicatrix, Hypertrophic; Disease Models, Animal; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Interferons; Male; Methylprednisolone; Mice; Mice, Nude; Middle Aged; Verapamil

2015