methylprednisolone has been researched along with u 74006f in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (9.38) | 18.7374 |
| 1990's | 22 (68.75) | 18.2507 |
| 2000's | 5 (15.63) | 29.6817 |
| 2010's | 2 (6.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anderson, DK; Andrus, PK; Cox, JW; Hall, ED; Yonkers, PA | 1 |
| Gerdin, B; Holtz, A | 1 |
| Adinolfi, D; Gaetani, P; Lombardi, D; Marzatico, F; Rodriguez y Baena, R | 1 |
| Becker, DP; Black, KL; Conklin, S; Ikezaki, K; King, WA | 1 |
| Hall, ED | 3 |
| Braughler, JM; Hall, ED; McCall, JM | 1 |
| Hall, ED; McCall, JM; Yonkers, PA | 1 |
| Hall, ED; Sun, FF; Taylor, BM; Yonkers, PA | 1 |
| Auchampach, JA; Cammarata, SK; Chin, JE; Fidler, SF; Griffin, RL; Haas, JV; Krzesicki, RF; Manning, AM; Richards, IM; Rosenbloom, CL | 1 |
| Jackson, TA; Kakuk, TJ; Ochoa, R | 1 |
| Eismont, FJ; Slucky, AV | 1 |
| Hall, ED; McCall, JM; Means, ED | 1 |
| Beattie, MS; Behrmann, DL; Bresnahan, JC | 1 |
| Farooque, M; Holtz, A; Olsson, Y | 1 |
| Dijkstra, CD; Polman, CH; Sontrop, K; Uitdehaag, BM | 1 |
| Aldrich, EF; Bracken, MB; Fazl, M; Fehlings, M; Herr, DL; Hitchon, PW; Holford, TR; Leo-Summers, L; Marshall, LF; Nockels, RP; Pascale, V; Perot, PL; Piepmeier, J; Shepard, MJ; Sonntag, VK; Wagner, F; Wilberger, JE; Winn, HR; Young, W | 1 |
| Werner, PC | 1 |
| Drobný, M; Krajnák, V; Krátky, M; Kurca, E; Michalík, J; Svaleková, A | 1 |
| Spapen, H; Vincent, JL; Zhang, H | 1 |
| Chiara, O; Fattori, L; Padalino, P; Ravizzini, C; Tiberio, G; Turconi, MG | 1 |
| Aldrich, EF; Bracken, MB; Fazl, M; Fehlings, MG; Herr, DL; Hitchon, PW; Holford, TR; Leo-Summers, L; Marshall, LF; Nockels, RP; Pascale, V; Perot, PL; Piepmeier, J; Shepard, MJ; Sonntag, VK; Wagner, F; Wilberger, JE; Winn, HR; Young, W | 1 |
| Akdemir, H; Karakücük, EI; Koc, RK; Menkü, A; Oktem, IS | 1 |
| Karaküçük, EI; Koç, RK; Kurtsoy, A; Meral, M; Oktem, IS; Paşaoğlu, H | 1 |
| Seidl, EC | 2 |
| Burmester, GR; Buttgereit, F; Fici, G; Schmid, D; Tripmacher, R; von Voigtlander, P | 1 |
| Döcke, WD; Engelhardt, L; Konertz, W; Kox, WJ; Schmutzler, M; Volk, HD; Volk, T | 1 |
| Engelhardt, L; Grune, T; Konertz, W; Kox, WJ; Laule, M; Pantke, U; Schmutzler, M; Stangl, K; Volk, T; Wernecke, KD | 1 |
| Sharma, A | 1 |
| Fehlings, MG; Furlan, JC | 1 |
11 review(s) available for methylprednisolone and u 74006f
| Article | Year |
|---|---|
Biochemistry and pharmacology of lipid antioxidants in acute brain and spinal cord injury.
Topics: Animals; Antioxidants; Brain Injuries; Free Radical Scavengers; Humans; Lipid Peroxidation; Lipid Peroxides; Methylprednisolone; Pregnatrienes; Spinal Cord Injuries; Steroids; Vitamin E | 1992 |
Pathophysiology of spinal cord injury. Current and future therapies.
Topics: Animals; Cats; Methylprednisolone; Mice; Prednisone; Pregnatrienes; Rats; Spinal Cord Injuries | 1989 |
New pharmacological treatment of acute spinal cord trauma.
Topics: Humans; Methylprednisolone; Prednisone; Pregnatrienes; Spinal Cord Injuries | 1988 |
Treatment of acute injury of the cervical spine.
Topics: Adolescent; Adult; Cervical Vertebrae; Diagnostic Imaging; Emergency Medical Services; Female; G(M1) Ganglioside; Humans; Hypothermia, Induced; Lipid Peroxides; Male; Methylprednisolone; Middle Aged; Naloxone; Physical Examination; Pregnatrienes; Resuscitation; Spinal Cord Injuries; Thyrotropin-Releasing Hormone | 1995 |
Therapeutic potential of the lazaroids (21-aminosteroids) in acute central nervous system trauma, ischemia and subarachnoid hemorrhage.
Topics: Animals; Antioxidants; Brain; Brain Injuries; Brain Ischemia; Humans; Lipid Peroxidation; Lipid Peroxides; Methylprednisolone; Pregnatrienes; Spinal Cord Injuries; Subarachnoid Hemorrhage | 1994 |
Neuroprotective actions of glucocorticoid and nonglucocorticoid steroids in acute neuronal injury.
Topics: Animals; Brain Injuries; Glucocorticoids; Humans; Lipid Peroxides; Methylprednisolone; Motor Neurons; Nerve Degeneration; Neurons; Pregnatrienes; Spinal Cord Injuries; Steroids | 1993 |
Potential therapeutic value of lazaroids in endotoxemia and other forms of sepsis.
Topics: Animals; Antioxidants; Endothelium; Endotoxemia; Free Radical Scavengers; Glucocorticoids; Humans; Methylprednisolone; Pregnatrienes; Reperfusion Injury; Sepsis; Shock, Septic; Structure-Activity Relationship | 1997 |
Classical corticosteroids and new lipid peroxidation inhibitors in the therapy of multiple organ failure (MOF).
Topics: Adrenal Cortex Hormones; Animals; Anti-Inflammatory Agents; Antioxidants; Clinical Trials as Topic; Free Radical Scavengers; Humans; Injections, Intraperitoneal; Lipid Peroxidation; Methylprednisolone; Multiple Organ Failure; Pregnatrienes; Prospective Studies; Rabbits; Randomized Controlled Trials as Topic; Respiratory Distress Syndrome; Sepsis; Shock, Septic; Zymosan | 1997 |
Promising pharmacological agents in the management of acute spinal cord injury.
Topics: Acute Disease; Anti-Inflammatory Agents; Drug Interactions; G(M1) Ganglioside; Humans; Methylprednisolone; Naloxone; Narcotic Antagonists; Neuroprotective Agents; Pregnatrienes; Research Design; Spinal Cord Injuries; Treatment Outcome | 1999 |
Promising pharmacological agents in the management of acute spinal cord injury.
Topics: Acute Disease; Antioxidants; G(M1) Ganglioside; Humans; Methylprednisolone; Naloxone; Narcotic Antagonists; Neuroprotective Agents; Pregnatrienes; Spinal Cord Injuries | 2000 |
Pharmacological treatment of acute spinal cord injury: how do we build on past success?
Topics: Acute Disease; Humans; Lipid Peroxidation; Methylprednisolone; Neuroprotective Agents; Pregnatrienes; Spinal Cord Injuries | 2001 |
5 trial(s) available for methylprednisolone and u 74006f
| Article | Year |
|---|---|
Administration of methylprednisolone for 24 or 48 hours or tirilazad mesylate for 48 hours in the treatment of acute spinal cord injury. Results of the Third National Acute Spinal Cord Injury Randomized Controlled Trial. National Acute Spinal Cord Injury
Topics: Adolescent; Adult; Analysis of Variance; Double-Blind Method; Drug Administration Schedule; Emergencies; Female; Humans; Injury Severity Score; Male; Methylprednisolone; Middle Aged; Neuroprotective Agents; Pregnatrienes; Spinal Cord Injuries; Time Factors | 1997 |
Methylprednisolone or tirilazad mesylate administration after acute spinal cord injury: 1-year follow up. Results of the third National Acute Spinal Cord Injury randomized controlled trial.
Topics: Activities of Daily Living; Acute Disease; Double-Blind Method; Drug Administration Schedule; Follow-Up Studies; Humans; Methylprednisolone; Nervous System; Neuroprotective Agents; Pregnatrienes; Spinal Cord Injuries; Time Factors | 1998 |
Influence of aminosteroid and glucocorticoid treatment on inflammation and immune function during cardiopulmonary bypass.
Topics: Antioxidants; Cardiopulmonary Bypass; Double-Blind Method; Female; Glucocorticoids; Humans; Immunosuppression Therapy; Inflammation; Interleukins; Male; Methylprednisolone; Middle Aged; Pregnatrienes; Preoperative Care; Tumor Necrosis Factor-alpha | 2001 |
Effects of different steroid treatment on reperfusion-associated production of reactive oxygen species and arrhythmias during coronary surgery.
Topics: Aged; Anesthesia; Anti-Inflammatory Agents; Arrhythmias, Cardiac; Biomarkers; Cardiac Surgical Procedures; Coronary Vessels; Electrocardiography, Ambulatory; Female; Glutathione; Hemodynamics; Humans; Lipid Peroxidation; Male; Malondialdehyde; Methylprednisolone; Middle Aged; Myocardial Reperfusion Injury; Oxidation-Reduction; Oxidative Stress; Postoperative Complications; Pregnatrienes; Reactive Oxygen Species; Steroids; Thiobarbituric Acid Reactive Substances | 2003 |
Blood alcohol concentration as a determinant of outcomes after traumatic spinal cord injury.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Disability Evaluation; Double-Blind Method; Ethanol; Female; Humans; Male; Methylprednisolone; Middle Aged; Neuroprotective Agents; Pregnatrienes; Recovery of Function; Spinal Cord Injuries; Trauma Severity Indices | 2013 |
16 other study(ies) available for methylprednisolone and u 74006f
| Article | Year |
|---|---|
Blocking weight-induced spinal cord injury in rats: therapeutic effect of the 21-aminosteroid U74006F.
Topics: Animals; Hindlimb; Lipid Peroxides; Male; Methylprednisolone; Paraplegia; Pregnatrienes; Psychomotor Performance; Rats; Rats, Inbred Strains; Spinal Cord Compression | 1991 |
Effect of high-dose methylprednisolone and U74006F on eicosanoid synthesis after subarachnoid hemorrhage in rats.
Topics: Animals; Dinoprostone; Eicosanoids; Epoprostenol; Lipid Peroxides; Lipoxygenase; Male; Methylprednisolone; Pregnatrienes; Prostaglandin D2; Rats; Rats, Inbred Strains; Subarachnoid Hemorrhage | 1991 |
Novel 21-aminosteroids prevent tumour associated neurological dysfunction.
Topics: Animals; Brain Neoplasms; Capillary Permeability; Chromans; Female; Lipid Peroxides; Methylprednisolone; Nervous System; Piperazines; Pregnatrienes; Rats; Rats, Inbred Strains; Reference Values | 1990 |
Attenuation of hemorrhagic shock by the non-glucocorticoid 21-aminosteroid U74006F.
Topics: Animals; Blood Gas Analysis; Blood Pressure; Cats; Female; Heart Rate; Hydrogen-Ion Concentration; Lipid Peroxides; Methylprednisolone; Pregnatrienes; Shock, Hemorrhagic | 1988 |
Lack of effect of postinjury treatment with methylprednisolone or tirilazad mesylate on the increase in eicosanoid levels in the acutely injured cat spinal cord.
Topics: Animals; Antioxidants; Cats; Eicosanoids; Female; Free Radical Scavengers; Leukotrienes; Methylprednisolone; Pregnatrienes; Spinal Cord Injuries; Time Factors; Treatment Outcome | 1995 |
Attenuation of oxidant-induced lung injury by 21-aminosteroids (lazaroids): correlation with the mRNA expression for E-selectin, P-selectin, ICAM-1, and VCAM-1.
Topics: Animals; Antioxidants; Cell Adhesion Molecules; E-Selectin; Free Radical Scavengers; Intercellular Adhesion Molecule-1; Lung; Lung Diseases; Male; Methylprednisolone; Neutrophils; Oxidants; P-Selectin; Platelet Membrane Glycoproteins; Pregnatrienes; Rats; Rats, Sprague-Dawley; RNA, Messenger; Vascular Cell Adhesion Molecule-1 | 1994 |
Tirilazad mesylate--effects of the 21-aminosteroid on the lymphoid system of laboratory animals: a comparison with the glucocorticoid methylprednisolone.
Topics: Animals; Central Nervous System; Dogs; Drug Evaluation, Preclinical; Female; Lymphatic System; Lymphocyte Activation; Macaca fascicularis; Male; Methylprednisolone; Pregnatrienes; Rats; Rats, Sprague-Dawley | 1995 |
Modeling of acute spinal cord injury in the rat: neuroprotection and enhanced recovery with methylprednisolone, U-74006F and YM-14673.
Topics: Animals; Azetidines; Dipeptides; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hindlimb; Lipid Peroxides; Locomotion; Methylprednisolone; Motor Activity; Pregnatrienes; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Thyrotropin-Releasing Hormone | 1994 |
Effect of the 21-aminosteroid U74006F and methylprednisolone on motor function recovery and oedema after spinal cord compression in rats.
Topics: Animals; Edema; Hindlimb; Lipid Peroxides; Male; Methylprednisolone; Motor Activity; Motor Skills; Pregnatrienes; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Compression | 1994 |
The effect of the 21-aminosteroid U74006F on the clinical course of acute experimental allergic encephalomyelitis.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Antioxidants; Disease Models, Animal; Dose-Response Relationship, Drug; Encephalomyelitis, Autoimmune, Experimental; Male; Methylprednisolone; Pregnatrienes; Rats; Rats, Inbred Lew | 1996 |
New drugs for improving injury outcome in spinal cord injuries.
Topics: Anti-Inflammatory Agents; Clinical Trials as Topic; Drug Therapy, Combination; G(M1) Ganglioside; Humans; Methylprednisolone; Neuroprotective Agents; Pregnatrienes; Spinal Cord Injuries; Treatment Outcome | 1997 |
[Local immune defects--products of free oxygen radicals].
Topics: Anti-Inflammatory Agents; Antioxidants; Brain Edema; Free Radical Scavengers; Humans; Male; Methylprednisolone; Middle Aged; Pregnatrienes; Radiography | 1997 |
Effect of methylprednisolone, tirilazad mesylate and vitamin E on lipid peroxidation after experimental spinal cord injury.
Topics: Animals; Antioxidants; Blood Pressure; Lipid Peroxidation; Male; Malondialdehyde; Methylprednisolone; Pregnatrienes; Rats; Spinal Cord Compression; Vitamin E | 1999 |
Lipid peroxidation and oedema in experimental brain injury: comparison of treatment with methylprednisolone, tirilazad mesylate and vitamin E.
Topics: Analysis of Variance; Animals; Antioxidants; Body Water; Brain Edema; Head Injuries, Closed; Lipid Peroxidation; Male; Malondialdehyde; Methylprednisolone; Pregnatrienes; Random Allocation; Rats; Vitamin E | 1999 |
Short-term effects of the 21-aminosteroid lazaroid tirilazad mesylate (PNU-74006F) and the pyrrolopyrimidine lazaroid PNU-101033E on energy metabolism of human peripheral blood mononuclear cells.
Topics: Adenosine Triphosphate; Anti-Inflammatory Agents; Brain Injuries; Calcium-Transporting ATPases; Cell Membrane; Cell Respiration; Concanavalin A; Dose-Response Relationship, Drug; Energy Metabolism; Enzyme Inhibitors; Humans; Leukocytes, Mononuclear; Lipid Peroxidation; Methylprednisolone; Neuroprotective Agents; Pregnatrienes; Protein Biosynthesis; Proteins; Pyrimidines; Pyrroles; Sodium-Potassium-Exchanging ATPase; Time Factors | 2001 |
Pharmacological management of acute spinal cord injury.
Topics: Acute Disease; Anti-Inflammatory Agents; Clinical Trials as Topic; Humans; Methylprednisolone; Naloxone; Neuroprotective Agents; Pregnatrienes; Spinal Cord Injuries; Time Factors; Treatment Outcome | 2012 |