Compounds > methylprednisolone

methylprednisolone and sirolimus

methylprednisolone has been researched along with sirolimus in 59 studies

Research

Studies (59)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (10.17)18.2507
2000's31 (52.54)29.6817
2010's21 (35.59)24.3611
2020's1 (1.69)2.80

Authors

AuthorsStudies
Andricopulo, AD; Moda, TL; Montanari, CA1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Auld, DS; Austin, CP; Huang, R; Moeller, TA; Sakamuru, S; Shinn, P; Shukla, SJ; Vanleer, D; Xia, M1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Asselin, I; Guérette, B; Kinoshita, I; Lille, S; Roy, R; Tremblay, JP; Vilquin, JT1
Alexander, JW; Levy, AE1
Böhler, T; Budde, K; Fritsche, L; Jauho, A; Korn, A; Lichter, S; Neumayer, HH; Waiser, J1
Alho, H; Harjula, AL; Ikonen, T; Maasilta, P; Salminen, US; Taskinen, E1
Aspeslet, LJ; Yatscoff, RW1
Deol, HS; Tuch, BE; Wright, DC1
Csizmadia, V; Gao, W; Hancock, WW; Smiley, ST; Turka, LA1
Coles, JG; Straatman, LP1
Ascher, NL; Chang, GJ; Freise, CE; Hirose, R; Mahanty, HD; Roberts, JP; Stock, PG; Vincenti, F1
Bak, T; Everson, GT; Kam, I; Stolpman, N; Trotter, JF; Trouillot, T; Wachs, M1
Harjula, AL; Lautenschlager, IT; Maasilta, PK; Salminen, US; Taskinen, EI1
Anasetti, C; Appelbaum, FR; Benito, AI; Deeg, HJ; Doney, K; Furlong, T; Martin, PJ; Nash, RA; Papayannopoulou, T; Storb, R; Sullivan, KM; Witherspoon, R1
Bäckman, L; Burke, JT; Kreis, H; Morales, JM; Taylor, R; Wilczek, H1
Jensik, SC; Mital, D; Podlasek, W1
Dong, V; Harada, H; Kishimoto, K; Najafian, N; Salama, AD; Sandner, SE; Sayegh, MH; Schmitt, I; Sho, M; Yamada, A1
Hu, RH; Lee, CY; Lee, PH; Tsai, MK1
Chueh, SC; Hu, RH; Lee, PH; Tsai, MK1
Bäckman, L; Brattström, C; Calne, R; Campistol, JM; Charpentier, B; Claesson, K; Durand, D; Groth, CG; Kreis, H; Lang, P; Morales, JM; Touraine, JL; Wramner, L1
Evenepoel, P; Geypens, B; Ghoos, Y; Kuypers, D; Maes, BD; Vanrenterghem, Y1
Asfar, S; Bailey, M; Gao, ZH; Garcia, B; Gelb, A; Grant, D; Quan, D; Sharpe, M; Stiller, C; Tucker, J; Wall, W; Zhang, Z; Zhong, R1
Alho, HS; Maasilta, PK; Päiväniemi, OE; Salminen, US; Wolff, CH1
Cretin, N; Dantal, J; Jappe, A; Li, Y; Margreiter, R; Viljoen, HG; Vítko, S; Weimar, W1
Ding, P; Oh, HK; Satmary, NA1
Clemente, R; de Gómez Dumm Nelva, T; Georgina, L; Gisela, C; Lausada, N1
Balitsari, A; Boletis, J; Filiopoulos, V; Kostakis, A; Lionaki, S; Stamataki, E; Zavos, G1
Andersson, B; Champlin, R; Couriel, DR; de Lima, MJ; Donato, M; Escalón, MP; Ghosh, S; Giralt, S; Hicks, K; Hosing, C; Hsu, Y; Ippoliti, C; Khouri, IF; Neumann, J; Saliba, R1
Feurer, I; Helderman, JH; Kizilisik, AT; Langone, AJ; Nylander, WA; Schaefer, HM; Shaffer, D1
Böhler, T; Budde, K; Glander, P; Gurragchaa, P; Kamar, N; Klupp, J; Neumayer, HH; Nolting, J; Reisener, K1
Dal Canton, A; Libetta, C; Meloni, F; Portalupi, V; Rampino, T; Sepe, V; Zucchi, M1
Beaumont, BW; Copeland, JW; Merrilees, MJ; Pilmore, HL1
Carreño, CA; Gadea, M1
Ahmad, N; Baker, RJ; Lewington, AJ; Lodge, JP; Newstead, CG; Pollard, SG; Smith, MP; Tibble, S1
Colgan, JP; Habermann, TM; Holtan, SG; Markovic, SN; Porrata, LF; Zent, CS1
Guo, S; Han, Y; Mai, H; Pan, H; Wang, L; Zhang, G; Zhang, X1
Iliadis, A; Laggouranis, A; Nakopoulou, L; Psimenou, E; Tsagalis, G1
Hafer, C; Hoeper, M; Kielstein, JT; Lorenzen, JM; Schonenberger, E1
Debska-Slizień, A; Konopa, J; Rutkowski, B; Tarasewicz, A; Zdrojewski, Z1
Mackenzie, M; Wood, LA1
De Vriese, AS; Vandecasteele, SJ; Vandewiele, B; Vanwalleghem, L1
Egi, M; Goto, K; Miyoshi, S; Okazaki, M; Oto, T; Sano, Y; Snell, GI; Takata, K; Toyooka, S; Yamane, M1
Doshi, MD; Gruber, SA1
Balal, M; Binokay, F; Demir, E; Erken, U; Kurt, C; Paydas, S; Sertdemir, Y; Sikgenc, MM1
Brandacher, G; Fuchs, D; Kurz, K; Schroecksnadel, S; Sucher, R1
Alfieri, F; de Sandes Freitas, TV; Felipe, CR; Galante, NZ; Harada, KM; Ikehara, E; Medina-Pestana, JO; Sampaio, EL; Tedesco-Silva Júnior, H1
Chen, GH; Fu, BS; He, JW; Jiang, N; Li, H; Wang, GS; Wang, GY; Wang, K; Yang, Y; Zhang, J1
Gerull, S; Halter, JP; Hostettler, KE; Lardinois, D; Roth, M; Savic, S; Tamm, M1
Klingebiel, T; Latgé, JP; Lehrnbecher, T; Roeger, F; Salzmann-Manrique, E; Schmidt, S; Schubert, R; Tramsen, L1
Bułanowski, M; Dębska-Ślizień, A; Rutkowski, B; Tarasewicz, A; Więcek, A1
Carmellini, M; Colussi, G; Ponticelli, C; Rigotti, P; Sandrini, S; Segoloni, G; Stefoni, S; Tisone, G1
Chen, JH; Feng, S; Jiang, H; Lang, XB; Li, H; Li, M; Lin, C; Lu, YY; Luo, C; Shao, X; Shen, XJ; Wang, YC; Wang, YY; Zhou, Q1
Bergan, S; Foss, A; Kloster-Jensen, K; Korsgren, O; Sahraoui, A; Scholz, H; Vethe, NT1
Dutra, RS; Fabreti-Oliveira, RA; Lasmar, MF; Nascimento, E; Nogueira-Machado, JA; Siqueira, RG1
Josephs, S; Lekwuttikarn, R; Teng, JM1
Comi, S; Figus, M; Lanzolla, G; Maglionico, MN; Marcocci, C; Marinò, M; Menconi, F; Piaggi, P; Posarelli, C1

Reviews

2 review(s) available for methylprednisolone and sirolimus

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
The monitoring of immunosuppressive drugs: a pharmacodynamic approach.
    Therapeutic drug monitoring, 1998, Volume: 20, Issue:5

    Topics: Azathioprine; Cyclosporine; Drug Monitoring; Humans; Immunosuppressive Agents; Methylprednisolone; Mycophenolic Acid; Sirolimus

1998

Trials

13 trial(s) available for methylprednisolone and sirolimus

ArticleYear
The in vivo effect of rapamycin derivative SDZ RAD on lymphocyte proliferation.
    Transplantation proceedings, 1998, Volume: 30, Issue:5

    Topics: Cells, Cultured; Cyclosporine; Everolimus; Humans; Immunosuppressive Agents; Kidney Transplantation; Lymphocyte Activation; Methylprednisolone; Polyenes; Sirolimus; T-Lymphocytes

1998
Sirolimus steady-state trough concentrations are not affected by bolus methylprednisolone therapy in renal allograft recipients.
    British journal of clinical pharmacology, 2002, Volume: 54, Issue:1

    Topics: Adult; Azathioprine; Drug Combinations; Female; Glucocorticoids; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Methylprednisolone; Middle Aged; Mycophenolic Acid; Sirolimus

2002
Sirolimus-based steroid-free maintenance immunosuppression.
    Transplantation proceedings, 2002, Volume: 34, Issue:5

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Antilymphocyte Serum; Black or African American; Child; Child, Preschool; Diabetes Mellitus; Drug Therapy, Combination; Female; Hispanic or Latino; Humans; Illinois; Immunosuppression Therapy; Immunosuppressive Agents; Kidney Transplantation; Male; Methylprednisolone; Middle Aged; Mycophenolic Acid; Reoperation; Sirolimus; Tissue Donors

2002
Effect of sirolimus in combination with low-dose cyclosporine and steroids on acute renal allograft rejection.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2003, Volume: 102, Issue:2

    Topics: Acute Disease; Adult; Cyclosporine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Glucocorticoids; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Methylprednisolone; Middle Aged; Prospective Studies; Sirolimus; Treatment Outcome

2003
Bicêtre hospital experience with sirolimus-based therapy in human renal transplantation: the Sirolimus European Renal Transplant Study.
    Transplantation proceedings, 2003, Volume: 35, Issue:3 Suppl

    Topics: Adrenal Cortex Hormones; Azathioprine; Cyclosporine; Drug Therapy, Combination; France; Graft Rejection; Hospitals, University; Humans; Hypercholesterolemia; Hypertriglyceridemia; Immunosuppressive Agents; Kidney Transplantation; Methylprednisolone; Prednisolone; Prednisone; Sirolimus

2003
Everolimus (Certican) 12-month safety and efficacy versus mycophenolate mofetil in de novo renal transplant recipients.
    Transplantation, 2004, Nov-27, Volume: 78, Issue:10

    Topics: Adolescent; Adult; Aged; Biopsy; Dose-Response Relationship, Drug; Double-Blind Method; Everolimus; Female; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Methylprednisolone; Middle Aged; Mycophenolic Acid; Safety; Sirolimus; Survival Analysis; Treatment Outcome

2004
A pilot study of calcineurin inhibitors (CNIs) and steroid avoidance immunosuppressive protocol among living donor kidney transplant recipients.
    Yonsei medical journal, 2004, Dec-31, Volume: 45, Issue:6

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antibodies, Monoclonal; Basiliximab; Calcineurin Inhibitors; Drug Therapy, Combination; Enzyme Inhibitors; Female; Glucocorticoids; Humans; Immunosuppressive Agents; Kidney Transplantation; Living Donors; Male; Methylprednisolone; Middle Aged; Mycophenolic Acid; Pilot Projects; Recombinant Fusion Proteins; Sirolimus

2004
Sirolimus in combination with tacrolimus and corticosteroids for the treatment of resistant chronic graft-versus-host disease.
    British journal of haematology, 2005, Volume: 130, Issue:3

    Topics: Adult; Aged; Chronic Disease; Drug Therapy, Combination; Female; Glucocorticoids; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Hyperlipidemias; Immunosuppressive Agents; Male; Methylprednisolone; Middle Aged; Proportional Hazards Models; Sirolimus; Tacrolimus

2005
Short-term results under three different immunosuppressive regimens at one center.
    Transplantation proceedings, 2006, Volume: 38, Issue:10

    Topics: Adrenal Cortex Hormones; Biopsy; Creatinine; Drug Therapy, Combination; Graft Rejection; Graft Survival; Histocompatibility Testing; Humans; Immunosuppressive Agents; Kidney Transplantation; Living Donors; Methylprednisolone; Mycophenolic Acid; Prednisone; Sirolimus; Survival Analysis; Treatment Outcome

2006
The effect of sirolimus- or cyclosporine-based immunosuppression effects on T-cell subsets in vivo.
    Kidney international, 2007, Volume: 72, Issue:1

    Topics: Adult; Anti-Inflammatory Agents; Cells, Cultured; Cyclosporine; Female; Gene Expression Regulation; Humans; Immunosuppressive Agents; Interferon-gamma; Interleukin-12; Interleukin-18; Interleukin-4; Interleukin-5; Kidney Transplantation; Male; Methylprednisolone; Middle Aged; Monocytes; Mycophenolic Acid; Sirolimus; Th1 Cells; Th2 Cells

2007
Poor tolerance of sirolimus in a steroid avoidance regimen for renal transplantation.
    Transplantation, 2008, Feb-27, Volume: 85, Issue:4

    Topics: Adrenal Cortex Hormones; Adult; Antibodies, Monoclonal; Basiliximab; Drug Therapy, Combination; Drug Tolerance; Female; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Methylprednisolone; Middle Aged; Recombinant Fusion Proteins; Sirolimus

2008
Steroid or tacrolimus withdrawal in renal transplant recipients using sirolimus.
    International urology and nephrology, 2011, Volume: 43, Issue:4

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Biopsy; Calcineurin Inhibitors; Drug Therapy, Combination; Female; Graft Rejection; Graft Survival; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Kaplan-Meier Estimate; Kidney Transplantation; Male; Methylprednisolone; Middle Aged; Prednisone; Sirolimus; Tacrolimus; Young Adult

2011
A randomized trial of everolimus and low-dose cyclosporine in renal transplantation: with or without steroids?
    Transplantation proceedings, 2014, Volume: 46, Issue:10

    Topics: Adult; Cyclosporine; Drug Therapy, Combination; Everolimus; Female; Glucocorticoids; Humans; Immunosuppressive Agents; Intention to Treat Analysis; Kidney Transplantation; Male; Methylprednisolone; Middle Aged; Prospective Studies; Sirolimus; Treatment Failure

2014

Other Studies

44 other study(ies) available for methylprednisolone and sirolimus

ArticleYear
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Identification of clinically used drugs that activate pregnane X receptors.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:1

    Topics: Animals; Cell Line, Tumor; Cytochrome P-450 CYP3A; Drug Interactions; Hep G2 Cells; Hepatocytes; Humans; Pharmaceutical Preparations; Pregnane X Receptor; Rats; Receptors, Steroid; Small Molecule Libraries; Species Specificity; Structure-Activity Relationship; Xenobiotics

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Myoblast allotransplantation in mice: degree of success varies depending on the efficacy of various immunosuppressive treatments.
    Transplantation proceedings, 1994, Volume: 26, Issue:6

    Topics: Animals; Azathioprine; Cyclosporine; Graft Survival; Immunosuppression Therapy; Immunosuppressive Agents; Methylprednisolone; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Muscles; Muscular Dystrophy, Animal; Mycophenolic Acid; Polyenes; Sirolimus; Transplantation, Homologous

1994
The significance of timing of additional short-term immunosuppression in the donor-specific transfusion/cyclosporine-treated rat.
    Transplantation, 1996, Jul-27, Volume: 62, Issue:2

    Topics: Animals; Antilymphocyte Serum; Biphenyl Compounds; Blood Donors; Blood Transfusion; Cyclosporine; Drug Administration Schedule; Graft Rejection; Graft Survival; Heart Transplantation; Immunosuppressive Agents; Male; Methylprednisolone; Polyenes; Rats; Rats, Inbred ACI; Rats, Inbred Lew; Sirolimus; Time Factors

1996
Effects of rapamycin analogue SDZ RAD on obliterative lesions in a porcine heterotopic bronchial allograft model.
    Transplantation proceedings, 1998, Volume: 30, Issue:5

    Topics: Animals; Azathioprine; Bronchi; Bronchiolitis Obliterans; Cartilage; Cyclosporine; Epithelium; Everolimus; Immunosuppressive Agents; Methylprednisolone; Mucous Membrane; Necrosis; Polyenes; Sirolimus; Swine; Transplantation, Heterotopic; Transplantation, Homologous

1998
A comparison of the sensitivity of pig and human peripheral blood mononuclear cells to the antiproliferative effects of traditional and newer immunosuppressive agents.
    Transplant immunology, 1999, Volume: 7, Issue:3

    Topics: Animals; Azathioprine; Cell Division; Cyclosporine; Diabetes Mellitus, Type 1; Graft Rejection; Guanidines; Humans; Immunosuppressive Agents; In Vitro Techniques; Islets of Langerhans Transplantation; Leukocytes, Mononuclear; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Methylprednisolone; Mycophenolic Acid; Phytohemagglutinins; Sirolimus; Species Specificity; Swine; Tacrolimus; Transplantation, Homologous

1999
Differential effects of cyclosporine A, methylprednisolone, mycophenolate, and rapamycin on CD154 induction and requirement for NFkappaB: implications for tolerance induction.
    Transplantation, 2000, Aug-15, Volume: 70, Issue:3

    Topics: Animals; Antibodies, Monoclonal; CD40 Ligand; Cyclosporine; Graft Survival; Heart Transplantation; Humans; Immunosuppressive Agents; In Vitro Techniques; Lymphocyte Activation; Membrane Glycoproteins; Methylprednisolone; Mice; Mice, Inbred BALB C; Mice, Knockout; Mycophenolic Acid; NF-kappa B; Sirolimus; T-Lymphocytes; Transplantation, Homologous

2000
Pediatric utilization of rapamycin for severe cardiac allograft rejection.
    Transplantation, 2000, Aug-15, Volume: 70, Issue:3

    Topics: Acute Disease; Adult; Animals; Antilymphocyte Serum; Child; Cyclosporine; Female; Graft Rejection; Heart Transplantation; Humans; Immunosuppressive Agents; Methotrexate; Methylprednisolone; Mycophenolic Acid; Platelet Count; Prednisone; Rabbits; Safety; Sirolimus; T-Lymphocytes; Tacrolimus

2000
A calcineurin inhibitor-sparing regimen with sirolimus, mycophenolate mofetil, and anti-CD25 mAb provides effective immunosuppression in kidney transplant recipients with delayed or impaired graft function.
    Clinical transplantation, 2000, Volume: 14, Issue:6

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Calcineurin; Calcineurin Inhibitors; Daclizumab; Female; Graft Rejection; Humans; Immunoglobulin G; Immunosuppressive Agents; Kidney; Kidney Transplantation; Male; Methylprednisolone; Middle Aged; Mycophenolic Acid; Prednisolone; Receptors, Interleukin-2; Retrospective Studies; Sirolimus

2000
Liver transplantation using sirolimus and minimal corticosteroids (3-day taper).
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2001, Volume: 7, Issue:4

    Topics: Cyclosporine; Female; Glucocorticoids; Graft Rejection; Humans; Immunosuppressive Agents; Liver Transplantation; Living Donors; Male; Methylprednisolone; Middle Aged; Sirolimus; Tacrolimus

2001
Immune cells and immunosuppression in a porcine bronchial model of obliterative bronchiolitis.
    Transplantation, 2001, Sep-27, Volume: 72, Issue:6

    Topics: Animals; Azathioprine; Bronchi; Bronchiolitis; Cyclosporine; Drug Therapy, Combination; Everolimus; Glucocorticoids; Graft Rejection; Immune System; Immunohistochemistry; Immunosuppression Therapy; Immunosuppressive Agents; Methylprednisolone; Sirolimus; Swine; Time Factors; Transplantation Immunology; Transplantation, Autologous; Transplantation, Homologous

2001
Sirolimus (rapamycin) for the treatment of steroid-refractory acute graft-versus-host disease.
    Transplantation, 2001, Dec-27, Volume: 72, Issue:12

    Topics: Acute Disease; Adolescent; Adult; Child; Child, Preschool; Drug Resistance; Female; Glucocorticoids; Graft vs Host Disease; Humans; Immunosuppressive Agents; Infant; Male; Methylprednisolone; Middle Aged; Pilot Projects; Retreatment; Sirolimus; Treatment Outcome

2001
New insights into the interactions between T-cell costimulatory blockade and conventional immunosuppressive drugs.
    Annals of surgery, 2002, Volume: 236, Issue:5

    Topics: Abatacept; Animals; Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation; Calcineurin Inhibitors; CD40 Ligand; CTLA-4 Antigen; Cyclosporine; Graft Rejection; Heart Transplantation; Immunoconjugates; Immunoglobulin Fc Fragments; Immunosuppressive Agents; Methylprednisolone; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Sirolimus; T-Lymphocytes; Tacrolimus; Transplantation, Homologous

2002
Linear correlation between sirolimus and cyclosporine trough levels in renal transplant patients.
    Transplantation proceedings, 2003, Volume: 35, Issue:1

    Topics: Adult; Cyclosporine; Drug Therapy, Combination; Female; Humans; Kidney Transplantation; Male; Methylprednisolone; Middle Aged; Prednisolone; Regression Analysis; Reperfusion; Sirolimus

2003
Influence of SDZ RAD vs. MMF on gastric emptying in renal transplant recipients.
    Clinical transplantation, 2003, Volume: 17, Issue:3

    Topics: Breath Tests; Case-Control Studies; Cyclosporine; Drug Therapy, Combination; Everolimus; Female; Gastric Emptying; Glucocorticoids; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Methylprednisolone; Middle Aged; Mycophenolic Acid; Sirolimus; Time Factors

2003
The long-term survival of baboon-to-monkey kidney and liver xenografts.
    Xenotransplantation, 2003, Volume: 10, Issue:5

    Topics: Animals; Antibodies, Heterophile; Cyclosporine; Drug Therapy, Combination; Female; Graft Survival; Immunosuppressive Agents; Kidney Transplantation; Liver Transplantation; Macaca fascicularis; Male; Methylprednisolone; Mycophenolic Acid; Papio; Sirolimus; Time Factors; Transplantation, Heterologous

2003
Cyclooxygenase-2 expression in experimental post-transplant obliterative bronchiolitis.
    The Journal of pathology, 2004, Volume: 204, Issue:3

    Topics: Animals; Azathioprine; Bronchi; Bronchiolitis Obliterans; Chondrocytes; Cyclooxygenase 2; Cyclosporine; Disease Models, Animal; Epithelial Cells; Everolimus; Fibroblasts; Fibrosis; Immunohistochemistry; Immunosuppressive Agents; Isoenzymes; Macrophages; Methylprednisolone; Postoperative Period; Prostaglandin-Endoperoxide Synthases; Sirolimus; Swine

2004
Effect of different immunosuppressive therapies on the lipid pattern in kidney-transplanted rats.
    Transplant international : official journal of the European Society for Organ Transplantation, 2005, Volume: 18, Issue:5

    Topics: Animals; Cholesterol; Creatinine; Cyclosporine; Erythrocyte Membrane; Hyperlipidemias; Immunosuppressive Agents; Kidney; Kidney Transplantation; Lipid Metabolism; Lipids; Male; Membrane Lipids; Methylprednisolone; Microsomes, Liver; Rats; Rats, Wistar; Sirolimus; Testis; Triglycerides; Urea

2005
Delayed renal graft function: the influence of immunosuppression.
    Transplantation proceedings, 2005, Volume: 37, Issue:5

    Topics: Adolescent; Adult; Analysis of Variance; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antilymphocyte Serum; Cadaver; Daclizumab; Female; Humans; Immunoglobulin G; Immunosuppression Therapy; Immunosuppressive Agents; Kidney Transplantation; Male; Methylprednisolone; Middle Aged; Mycophenolic Acid; Regression Analysis; Retrospective Studies; Sirolimus; Tacrolimus; Tissue Donors

2005
Validation of immunological biomarkers for the pharmacodynamic monitoring of immunosuppressive drugs in humans.
    Therapeutic drug monitoring, 2007, Volume: 29, Issue:1

    Topics: Adult; Antigens, CD; Biomarkers; CD4-Positive T-Lymphocytes; Cell Proliferation; Concanavalin A; Cyclosporine; Drug Monitoring; Humans; Immunosuppressive Agents; Interleukin-2; Interleukin-2 Receptor alpha Subunit; Lymphocyte Activation; Methylprednisolone; Middle Aged; Mycophenolic Acid; Receptors, Transferrin; Reproducibility of Results; Sirolimus; Tacrolimus; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha

2007
Epithelial-to-mesenchymal transition of human proximal tubular epithelial cells: effects of rapamycin, mycophenolate, cyclosporin, azathioprine, and methylprednisolone.
    Transplantation, 2007, Mar-27, Volume: 83, Issue:6

    Topics: Actins; Azathioprine; Cell Differentiation; Cell Proliferation; Cells, Cultured; Cyclosporine; Epithelial Cells; Fibroblasts; Humans; Immunosuppressive Agents; Kidney Transplantation; Kidney Tubules, Proximal; Methylprednisolone; Mycophenolic Acid; Sirolimus; Transforming Growth Factor beta; Versicans

2007
Case report of a kidney transplant recipient converted to everolimus due to malignancy: resolution of bronchiolitis obliterans organizing pneumonia without everolimus discontinuation.
    Transplantation proceedings, 2007, Volume: 39, Issue:3

    Topics: Adrenal Cortex Hormones; Azathioprine; Cryptogenic Organizing Pneumonia; Cyclosporine; Everolimus; Female; Humans; Kidney Transplantation; Methylprednisolone; Middle Aged; Papillomavirus Infections; Polycystic Kidney Diseases; Postoperative Complications; Sirolimus; Vaginal Neoplasms

2007
mTOR inhibitor monotherapy is insufficient to suppress viremia and disease progression in Epstein-Barr virus-driven lymphoproliferative disorders (EBV-LPD).
    American journal of hematology, 2008, Volume: 83, Issue:8

    Topics: Aged; Disease Progression; Drug Therapy, Combination; Female; Herpesvirus 4, Human; Humans; Immunoglobulins, Intravenous; Lymphoproliferative Disorders; Male; Methylprednisolone; Middle Aged; Protein Kinases; Sirolimus; TOR Serine-Threonine Kinases; Treatment Failure; Viremia

2008
Rapamycin, mycophenolate mofetil, methylprednisolone, and cytotoxic T-lymphocyte-associated antigen 4 immunoglobulin-based conditioning regimen to induce partial tolerance to hind limb allografts without cytoreductive conditioning.
    Transplantation proceedings, 2008, Volume: 40, Issue:5

    Topics: Abatacept; Acetaminophen; Analgesia; Analgesics; Animals; Buprenorphine; Hindlimb; Immune Tolerance; Immunoconjugates; Immunosuppressive Agents; Male; Methylprednisolone; Mycophenolic Acid; Pain, Postoperative; Rats; Rats, Inbred BN; Rats, Inbred Lew; Sirolimus; Transplantation Conditioning; Transplantation, Homologous

2008
Rapamycin for focal segmental glomerulosclerosis: a report of 3 cases.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2009, Volume: 54, Issue:2

    Topics: Adult; Drug Therapy, Combination; Female; Glomerulosclerosis, Focal Segmental; Glucocorticoids; Humans; Immunosuppressive Agents; Male; Methylprednisolone; Middle Aged; Sirolimus

2009
Failed rescue therapy with rapamycin after paraquat intoxication.
    Clinical toxicology (Philadelphia, Pa.), 2010, Volume: 48, Issue:1

    Topics: Anti-Inflammatory Agents; Antioxidants; Dialysis; Fatal Outcome; Herbicides; Humans; Intracellular Signaling Peptides and Proteins; Male; Methylprednisolone; Middle Aged; Oxygen Inhalation Therapy; Paraquat; Protein Serine-Threonine Kinases; Pulmonary Fibrosis; Reactive Oxygen Species; Respiratory Insufficiency; Sirolimus; Suicide; TOR Serine-Threonine Kinases; Treatment Failure

2010
Rapamycin as a therapy of choice after renal transplantation in a patient with tuberous sclerosis complex.
    Transplantation proceedings, 2009, Volume: 41, Issue:9

    Topics: Adult; Angiofibroma; Facial Neoplasms; Female; Humans; Immunosuppressive Agents; Kidney Transplantation; Methylprednisolone; Mutation; Sirolimus; Tacrolimus; Tuberous Sclerosis; Tuberous Sclerosis Complex 1 Protein; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins

2009
Lingual angioedema associated with everolimus.
    Acta oncologica (Stockholm, Sweden), 2010, Volume: 49, Issue:1

    Topics: Angioedema; Anti-Allergic Agents; Anti-Inflammatory Agents; Antineoplastic Agents; Carcinoma, Renal Cell; Diphenhydramine; Epinephrine; Everolimus; Humans; Kidney Neoplasms; Male; Methylprednisolone; Middle Aged; Sirolimus; Tongue Diseases

2010
Diffuse alveolar hemorrhage induced by everolimus.
    Chest, 2010, Volume: 137, Issue:2

    Topics: Biopsy; Bronchoscopy; Diagnosis, Differential; Dose-Response Relationship, Drug; Everolimus; Female; Follow-Up Studies; Glucocorticoids; Graft Rejection; Hemoptysis; Humans; Immunosuppressive Agents; Kidney Transplantation; Methylprednisolone; Middle Aged; Sirolimus

2010
Calcineurin inhibitor-related cholestasis complicating lung transplantation.
    The Annals of thoracic surgery, 2010, Volume: 89, Issue:5

    Topics: Adult; Calcineurin; Calcineurin Inhibitors; Cholestasis; Disease Progression; Fatal Outcome; Female; Graft Rejection; Humans; Hypertension, Pulmonary; Immunosuppressive Agents; Living Donors; Lung Transplantation; Methylprednisolone; Pneumonia, Bacterial; Postoperative Complications; Pseudomonas Infections; Risk Assessment; Sirolimus; Tacrolimus; Transplantation Immunology

2010
Conversion to sirolimus in African American renal allograft recipients undergoing early steroid withdrawal: intermediate-term risks and benefits.
    Transplantation, 2010, May-15, Volume: 89, Issue:9

    Topics: Adrenal Cortex Hormones; Adult; Antibodies, Monoclonal; Antilymphocyte Serum; Black People; Drug Administration Schedule; Female; Follow-Up Studies; Hepatitis C; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Methylprednisolone; Middle Aged; Mycophenolic Acid; Renal Dialysis; Reoperation; Risk Assessment; Sirolimus; Tacrolimus; Transplantation, Homologous

2010
Bone disease in renal transplantation and pleotropic effects of vitamin D therapy.
    Transplantation proceedings, 2010, Volume: 42, Issue:7

    Topics: Azathioprine; Bone Density; Bone Diseases; Bone Diseases, Metabolic; Creatinine; Female; Humans; Kidney Transplantation; Lipids; Male; Methylprednisolone; Mycophenolic Acid; Osteonecrosis; Osteoporosis; Sirolimus; Vitamin D

2010
Influence of immunosuppressive agents on tryptophan degradation and neopterin production in human peripheral blood mononuclear cells.
    Transplant immunology, 2011, Volume: 25, Issue:2-3

    Topics: Cells, Cultured; Cyclosporine; GTP Cyclohydrolase; Humans; Immunosuppressive Agents; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Kynurenine; Leukocytes, Mononuclear; Methylprednisolone; Mycophenolic Acid; Neopterin; Phytohemagglutinins; Sirolimus; Tacrolimus; Tryptophan

2011
Symptomatic osteonecrosis of the femoral head after adult orthotopic liver transplantation.
    Chinese medical journal, 2012, Volume: 125, Issue:14

    Topics: Adult; Aged; Cyclosporine; Female; Femur Head Necrosis; Humans; Immunosuppressive Agents; Liver Transplantation; Male; Methylprednisolone; Middle Aged; Osteonecrosis; Retrospective Studies; Risk Factors; Sirolimus; Tacrolimus; Young Adult

2012
Calcineurin inhibitors in bronchiolitis obliterans syndrome following stem cell transplantation.
    The European respiratory journal, 2014, Volume: 43, Issue:1

    Topics: Adult; Bronchiolitis Obliterans; Calcineurin Inhibitors; Cell Proliferation; Cells, Cultured; Cyclosporine; Drug Therapy, Combination; Everolimus; Female; Forced Expiratory Volume; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Lung; Male; Methylprednisolone; Mycophenolic Acid; Myofibroblasts; Sirolimus; Tacrolimus

2014
Immunosuppressive compounds exhibit particular effects on functional properties of human anti-Aspergillus Th1 cells.
    Infection and immunity, 2014, Volume: 82, Issue:6

    Topics: Apoptosis; Aspergillosis; Aspergillus fumigatus; Cell Proliferation; Cells, Cultured; Cyclosporine; Cytokines; Humans; Immunosuppressive Agents; Interferon-gamma; Methylprednisolone; Mycophenolic Acid; Sirolimus; Th1 Cells

2014
Everolimus in immunosuppressive treatment after kidney transplantation in a patient with tuberous sclerosis: case report.
    Transplantation proceedings, 2014, Volume: 46, Issue:8

    Topics: Adult; Creatinine; Delayed Graft Function; Everolimus; Female; Humans; Immunosuppressive Agents; Kidney Transplantation; Methylprednisolone; Sirolimus; TOR Serine-Threonine Kinases; Tuberous Sclerosis

2014
Effects of rapamycin against paraquat-induced pulmonary fibrosis in mice.
    Journal of Zhejiang University. Science. B, 2015, Volume: 16, Issue:1

    Topics: Actins; Animals; Body Weight; Collagen; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Herbicides; Immunohistochemistry; Immunosuppressive Agents; Lung; Male; Methylprednisolone; Mice; Mice, Inbred C57BL; Paraquat; Prognosis; Pulmonary Fibrosis; Sirolimus; Transforming Growth Factor beta1; Treatment Outcome

2015
Treatment with Tacrolimus and Sirolimus Reveals No Additional Adverse Effects on Human Islets In Vitro Compared to Each Drug Alone but They Are Reduced by Adding Glucocorticoids.
    Journal of diabetes research, 2016, Volume: 2016

    Topics: Adult; Apoptosis; Body Mass Index; Cells, Cultured; Cytokines; Drug Synergism; Female; Glucocorticoids; Glucose; Humans; Immunosuppressive Agents; Inflammation; Insulin; Insulin Secretion; Islets of Langerhans; Islets of Langerhans Transplantation; Male; Methylprednisolone; Middle Aged; Polymerase Chain Reaction; RNA, Messenger; Sirolimus; Tacrolimus

2016
Effects of immunotherapy induction on outcome and graft survival of kidney-transplanted patients with different immunological risk of rejection.
    BMC nephrology, 2019, 08-13, Volume: 20, Issue:1

    Topics: Adult; Age Factors; Antilymphocyte Serum; Cadaver; Cyclosporine; Female; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Immunotherapy; Kidney Transplantation; Living Donors; Maintenance Chemotherapy; Male; Methylprednisolone; Mycophenolic Acid; Retrospective Studies; Risk; Sex Factors; Sirolimus; Survival Rate; T-Lymphocytes; Tacrolimus; Time Factors; Treatment Outcome

2019
Successful Medical Management of Life-threatening Hepatic Hemangioma in Neonates.
    Pediatrics, 2019, Volume: 144, Issue:4

    Topics: Drug Therapy, Combination; Embolization, Therapeutic; Female; Glucocorticoids; Hemangioma; Hepatic Artery; Humans; Infant, Newborn; Liver Neoplasms; Male; Methylprednisolone; Propranolol; Sirolimus; Vasodilator Agents

2019
Sirolimus as a second-line treatment for Graves' orbitopathy.
    Journal of endocrinological investigation, 2022, Volume: 45, Issue:11

    Topics: Exophthalmos; Graves Ophthalmopathy; Humans; Methylprednisolone; Quality of Life; Sirolimus; Treatment Outcome

2022