methylprednisolone has been researched along with simvastatin in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 6 (35.29) | 29.6817 |
| 2010's | 9 (52.94) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Battisti, E; Gennari, C; Giordano, N; Mattii, G; Senesi, M; Villanova, M | 1 |
| Bonilla, E; Francis, L; Fuller, C; Nakhla, H; Neupane, H; Perl, A; Soforo, E | 1 |
| Wang, J; Wang, L; Wang, Y; Xu, Y; Yang, J | 1 |
| Asada, A; Iwaki, H; Iwakiri, K; Kaneshiro, Y; Kobayashi, A; Masada, T; Oda, Y; Takaoka, K | 1 |
| Arnaudova, R; Krebs, R; Lemström, KB; Nykänen, AI; Rouvinen, E; Syrjälä, S; Tuuminen, R | 1 |
| Beck-Peccoz, P; Campi, I; Covelli, D; Currò, N; D'Ambrosio, R; Gianelli, U; Maggioni, M; Salvi, M; Vannucchi, G | 1 |
| Kim, EJ; Kim, SH; Kong, HS; Lee, J; Lee, JR; Suh, CS; Youm, HW | 1 |
| Deas, C; Kahl, CG | 1 |
| Jiang, Y; Lin, L; Liu, K; Yu, Y; Zhou, Z | 1 |
1 review(s) available for methylprednisolone and simvastatin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
16 other study(ies) available for methylprednisolone and simvastatin
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Polymyositis associated with simvastatin.
Topics: Adult; Anticholesteremic Agents; Humans; Hypercholesterolemia; Lovastatin; Male; Methylprednisolone; Polymyositis; Simvastatin | 1997 |
Fatal toxic myopathy attributed to propofol, methylprednisolone, and cyclosporine after prior exposure to colchicine and simvastatin.
Topics: Aged; Colchicine; Creatine Kinase; Cyclosporine; Dose-Response Relationship, Drug; Drug Interactions; Fatal Outcome; Humans; Male; Methylprednisolone; Mitochondria; Propofol; Rhabdomyolysis; Simvastatin; Vacuoles | 2008 |
[An experimental study on treatment of steroid-associated femoral head necrosis with simvastatin and BMSCs transplantation].
Topics: Animals; Bone Marrow Transplantation; Cells, Cultured; Disease Models, Animal; Femur Head Necrosis; Male; Methylprednisolone; Rabbits; Random Allocation; Simvastatin; Stem Cell Transplantation; Treatment Outcome | 2008 |
Effect of simvastatin on steroid-induced osteonecrosis evidenced by the serum lipid level and hepatic cytochrome P4503A in a rabbit model.
Topics: Animals; Cytochrome P-450 CYP3A; Female; Glucocorticoids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Lipids; Liver; Methylprednisolone; Osteonecrosis; Pravastatin; Probucol; Rabbits; Simvastatin | 2008 |
Combined donor simvastatin and methylprednisolone treatment prevents ischemia-reperfusion injury in rat cardiac allografts through vasculoprotection and immunomodulation.
Topics: Animals; Glucuronosyltransferase; Graft Survival; Heart Transplantation; Hyaluronan Synthases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoxia-Inducible Factor 1, alpha Subunit; Immunomodulation; Methylprednisolone; rac GTP-Binding Proteins; Rats; Rats, Inbred WF; Reperfusion Injury; rho-Associated Kinases; rhoA GTP-Binding Protein; RNA, Messenger; Simvastatin; Tissue Donors; Transplantation, Homologous | 2013 |
Statins may increase the risk of liver dysfunction in patients treated with steroids for active graves' orbitopathy.
Topics: Chemical and Drug Induced Liver Injury; Female; Glucocorticoids; Graves Ophthalmopathy; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Methylprednisolone; Middle Aged; Simvastatin | 2015 |
A combination of simvastatin and methylprednisolone improves the quality of vitrified-warmed ovarian tissue after auto-transplantation.
Topics: Animals; Anticholesteremic Agents; Cryopreservation; Drug Therapy, Combination; Female; Glucocorticoids; Methylprednisolone; Mice; Ovary; Reperfusion Injury; Simvastatin; Tissue Transplantation; Transplantation, Autologous; Vitrification | 2015 |
Exercise-Induced Anaphylaxis in an Air Force Aviator Taking a HMG-CoA Reductase Inhibitor: A Case Report and Review of the Presentation, Diagnoses, and Treatment.
Topics: Anaphylaxis; Asthma, Exercise-Induced; Glucocorticoids; Histamine H2 Antagonists; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Methylprednisolone; Middle Aged; Military Personnel; Pilots; Ranitidine; Simvastatin; Urticaria | 2017 |
Effects of Simvastatin on Cartilage Homeostasis in Steroid-Induced Osteonecrosis of Femoral Head by Inhibiting Glucocorticoid Receptor.
Topics: Animals; Cartilage; Chickens; Femur Head; Homeostasis; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Methylprednisolone; Osteonecrosis; Receptors, Glucocorticoid; Simvastatin | 2022 |