methylprednisolone and pentoxifylline

methylprednisolone has been researched along with pentoxifylline in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (24.14)18.2507
2000's11 (37.93)29.6817
2010's10 (34.48)24.3611
2020's1 (3.45)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Abramowicz, D; Bemelmans, MH; Buurman, WA; Goldman, M; Gouma, DJ1
Fung, JJ; Murase, N; Pan, F; Rao, AS; Rice, G; Singer, JW; Starzl, TE; Subbotin, V; Sun, H; Todo, S; Valdivia, LA1
Chelstrom, LM; Clementson, D; Covalciuc, K; Gunther, R; Irvin, JD; Johnson, B; Myers, DE; Schneider, EA; Uckun, FM; Wendorf, HR1
Arimura, K; Higuchi, I; Izumo, S; Kawabata, M; Kubota, H; Maruyama, Y; Nakagawa, M; Nakahara, K; Osame, M1
Briggs, WA; Burdick, J; Choi, M; Eustace, J; Gimenez, LF; Mathew, S; Scheel, PJ1
Briggs, WA; Burdick, J; Choi, M; Orgul, O; Scheel, PJ; Wu, Q1
Briggs, WA; Burdick, JF; Choi, MJ; Eustace, J; Gimenez, LF; Scheel, PJ1
Dommerich, S; Graumüller, S; Hoff, M; Ostwald, J1
Alessi, E; Marzano, AV; Vanotti, M1
Cankaya, H; Içli, M; Kiriş, M; Kutluhan, A1
Akkoç, A; Misirlioğlu, D; Polat, U; Sevimli, A; Uğuz, C; Yalçin, M1
Ben Gamra, O; Ben Rejab, I; Bhar, H; El Khedim, A; Hariga, I; Mbarek, C; Sghaier, L; Zribi, S1
Bruschini, L; Bruschini, P; Dallan, I; Fattorp, B; Ferraro, G; Nacci, A; Rognini, F; Traino, AC1
Aricha, R; Feferman, T; Fuchs, S; Menon, RT; Souroujon, MC1
Breil, J; Labus, J; Michel, O; Stützer, H1
Aydin, F; Fidan, E; Fidan, M; Kavgaci, H; Ozdemir, F1
Bisaga, GN; Boĭko, AN; Mel'nik, IuB; Odinak, MM; Popova, NF1
Aktas, M; Erken, HY; Ofluoglu, O; Topal, C; Yildiz, M1
Grzeszczak, W; Król, R; Więcek, A; Wystrychowski, A; Wystrychowski, G; Wystrychowski, W1
Barton, B; Casey, L; Cuthbert, J; Dasarathy, S; Holbein, MEB; Kroll-Desrosiers, A; McClain, CJ; McCullough, AJ; Min, HA; Mitchell, M; Nagy, LE; Radaeva, S; Szabo, G; Tornai, D1

Reviews

2 review(s) available for methylprednisolone and pentoxifylline

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Meta-analysis for the effect of medical therapy vs. placebo on recovery of idiopathic sudden hearing loss.
    The Laryngoscope, 2010, Volume: 120, Issue:9

    Topics: Administration, Oral; Citrates; Controlled Clinical Trials as Topic; Dexamethasone; Dextrans; Epoprostenol; Follow-Up Studies; Hearing Loss, Sudden; Humans; Infusions, Intravenous; Methylprednisolone; Pentoxifylline; Prednisone; Procaine

2010

Trials

3 trial(s) available for methylprednisolone and pentoxifylline

ArticleYear
Therapeutic trials in 200 patients with HTLV-I-associated myelopathy/ tropical spastic paraparesis.
    Journal of neurovirology, 1996, Volume: 2, Issue:5

    Topics: Administration, Oral; Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Antiviral Agents; Ascorbic Acid; Azathioprine; Danazol; Erythromycin; Estrogen Antagonists; Female; Fosfomycin; Glycerol; Human T-lymphotropic virus 1; Humans; Hydrocortisone; Immunoglobulins, Intravenous; Immunosuppressive Agents; Injections, Intramuscular; Injections, Intravenous; Injections, Spinal; Interferon-gamma; Leukapheresis; Male; Methylprednisolone; Middle Aged; Paraparesis, Tropical Spastic; Pentoxifylline; Plasmapheresis; Propiophenones; Respiratory Therapy; Ribonucleosides; Sulfasalazine; Thyrotropin-Releasing Hormone; Vasodilator Agents

1996
[Possibilities of treatment of multiple sclerosis exacerbations without corticosteroids: a role of metabolic and antioxidant therapy].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2011, Volume: 111, Issue:2

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Antioxidants; Autoantibodies; Cognition; Disease Progression; Drug Combinations; Drug Therapy, Combination; Female; Flavin Mononucleotide; Humans; Inosine Diphosphate; Lipid Peroxidation; Male; Methylprednisolone; Middle Aged; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Myelin Sheath; Niacinamide; Pentoxifylline; Succinates; Vitamin B Complex; Young Adult

2011
IL-1 receptor antagonist plus pentoxifylline and zinc for severe alcohol-associated hepatitis.
    Hepatology (Baltimore, Md.), 2022, Volume: 76, Issue:4

    Topics: Adrenal Cortex Hormones; Adult; End Stage Liver Disease; Female; Hepatitis, Alcoholic; Humans; Interleukin 1 Receptor Antagonist Protein; Male; Methylprednisolone; Middle Aged; Pentoxifylline; Receptors, Interleukin-1; Severity of Illness Index; Zinc

2022

Other Studies

24 other study(ies) available for methylprednisolone and pentoxifylline

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
In vivo T cell activation by anti-CD3 monoclonal antibody induces soluble TNF receptor release in mice. Effects of pentoxifylline, methylprednisolone, anti-TNF, and anti-IFN-gamma antibodies.
    Journal of immunology (Baltimore, Md. : 1950), 1994, Jul-15, Volume: 153, Issue:2

    Topics: Animals; Antibodies, Monoclonal; CD3 Complex; Cricetinae; Female; Interferon-gamma; Lymphocyte Activation; Methylprednisolone; Mice; Mice, Inbred DBA; Pentoxifylline; Receptors, Tumor Necrosis Factor; Renal Circulation; T-Lymphocytes; Tumor Necrosis Factor-alpha

1994
Perioperative treatment with phosphatidic acid inhibitor (Lisofylline leads to prolonged survival of hearts in the guinea pig to rat xenotransplant model.
    Transplantation proceedings, 1996, Volume: 28, Issue:2

    Topics: Adjuvants, Immunologic; Animals; Antibodies, Heterophile; Complement C3; Graft Survival; Guinea Pigs; Heart Transplantation; Immunoglobulin G; Immunoglobulin M; Immunosuppressive Agents; Intraoperative Period; Methylprednisolone; Pentoxifylline; Phosphatidic Acids; Rats; Rats, Inbred Lew; Transplantation, Heterologous

1996
Toxicity profile of the investigational new biotherapeutic agent, B43 (anti-CD19)-pokeweed antiviral protein immunotoxin.
    Leukemia & lymphoma, 1996, Volume: 22, Issue:1-2

    Topics: Animals; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antigens, CD19; Antineoplastic Agents, Phytogenic; Cardiomyopathies; Chemical and Drug Induced Liver Injury; Dopamine; Female; Immunotoxins; Injections, Intraperitoneal; Injections, Intravenous; Kidney Tubular Necrosis, Acute; Methylprednisolone; Mice; Mice, Inbred BALB C; Muscular Diseases; N-Glycosyl Hydrolases; Pentoxifylline; Plant Proteins; Ribosome Inactivating Proteins, Type 1; Single-Blind Method

1996
Pentoxifylline potentiates in vitro lymphocyte suppression by glucocorticoids and immunosuppressive drugs.
    Journal of clinical pharmacology, 1998, Volume: 38, Issue:6

    Topics: Adult; Aged; Analysis of Variance; Cyclosporine; Drug Synergism; Female; Glucocorticoids; Humans; Immunosuppressive Agents; Lymphocytes; Male; Methylprednisolone; Middle Aged; Pentoxifylline; Prednisolone

1998
Lymphocyte suppression by rolipram with other immunosuppressive drugs.
    Journal of clinical pharmacology, 1999, Volume: 39, Issue:8

    Topics: Adult; Aged; Cell Division; Cohort Studies; Cyclosporine; Dose-Response Relationship, Drug; Female; Humans; Immunosuppressive Agents; Interferon-gamma; Interleukin-10; Leukocytes, Mononuclear; Lymphocytes; Male; Methylprednisolone; Middle Aged; Pentoxifylline; Phosphodiesterase Inhibitors; Pyrrolidinones; Rolipram; Tacrolimus; Thymidine; Tritium

1999
Lymphocyte suppression by glucocorticoids with cyclosporine, tacrolimus, pentoxifylline, and mycophenolic acid.
    Journal of clinical pharmacology, 1999, Volume: 39, Issue:2

    Topics: Cells, Cultured; Cyclosporine; Drug Combinations; Enzyme Inhibitors; Glucocorticoids; Humans; Immunosuppressive Agents; Kidney Failure, Chronic; Lymphocytes; Methylprednisolone; Mycophenolic Acid; Pentoxifylline; Prednisolone; Tacrolimus

1999
[Influence of rhinologic usual and unusual drugs on fibroblasts from nasal polyps in cell culture].
    Laryngo- rhino- otologie, 2003, Volume: 82, Issue:6

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Androstadienes; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Beclomethasone; Calcium Channel Blockers; Cells, Cultured; Culture Media; Diclofenac; Fibroblasts; Fluticasone; Glucocorticoids; Hematologic Agents; Humans; In Vitro Techniques; Mesalamine; Methylprednisolone; Mometasone Furoate; Muscarinic Agonists; Nasal Polyps; Pentoxifylline; Pilocarpine; Piroxicam; Prednisolone; Pregnadienediols; Time Factors; Timolol; Verapamil

2003
Widespread livedoid vasculopathy.
    Acta dermato-venereologica, 2003, Volume: 83, Issue:6

    Topics: Adult; Autoimmune Diseases; Biopsy, Needle; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Immunohistochemistry; Infusions, Intravenous; Methylprednisolone; Pentoxifylline; Physical Examination; Risk Assessment; Severity of Illness Index; Skin Diseases, Vascular; Treatment Outcome

2003
Retrospective analysis of our cases with sudden hearing loss.
    The Journal of otolaryngology, 2003, Volume: 32, Issue:6

    Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Anticoagulants; Audiometry, Pure-Tone; Auditory Threshold; Child; Dextrans; Diazepam; Drug Therapy, Combination; Female; Glucocorticoids; Hearing Loss, Sudden; Humans; Male; Methylprednisolone; Middle Aged; Papaverine; Pentoxifylline; Prognosis; Retrospective Studies; Risk Factors; Treatment Outcome; Vasodilator Agents

2003
The effects of vitamin A, pentoxyfylline and methylprednisolone on experimentally induced amyloid arthropathy in brown layer chicks.
    Avian pathology : journal of the W.V.P.A, 2005, Volume: 34, Issue:2

    Topics: Amyloidosis; Animals; Anti-Inflammatory Agents; Chickens; Enzyme Inhibitors; Freund's Adjuvant; Joint Diseases; Methylprednisolone; Pentoxifylline; Poultry Diseases; Vitamin A

2005
[Idiopathic sudden sensorineural hearing loss. What's the appropriate management?].
    La Tunisie medicale, 2007, Volume: 85, Issue:10

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Aspirin; Audiometry, Pure-Tone; Child; Female; Glucocorticoids; Hearing; Hearing Loss, Sudden; Hospitalization; Humans; Hyperbaric Oxygenation; Male; Methylprednisolone; Middle Aged; Nafronyl; Pentoxifylline; Platelet Aggregation Inhibitors; Recovery of Function; Retrospective Studies; Treatment Outcome; Vasodilator Agents

2007
Transtympanic steroids in refractory sudden hearing loss. Personal experience.
    Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale, 2006, Volume: 26, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Audiometry, Pure-Tone; Drug Therapy, Combination; Female; Fibrinolytic Agents; Hearing Loss, Sensorineural; Hearing Loss, Sudden; Heparin, Low-Molecular-Weight; Humans; Injections; Male; Methylprednisolone; Middle Aged; Pentoxifylline; Prospective Studies; Severity of Illness Index; Sodium Bicarbonate; Tympanic Membrane; Vasodilator Agents

2006
Suppression of experimental autoimmune myasthenia gravis by combination therapy: pentoxifylline as a steroid-sparing agent.
    Journal of neuroimmunology, 2008, Sep-15, Volume: 201-202

    Topics: Animals; Antibodies; Body Weight; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Gene Expression Regulation; Glucocorticoids; Methylprednisolone; Muscle, Skeletal; Myasthenia Gravis, Autoimmune, Experimental; Pentoxifylline; Phosphodiesterase Inhibitors; Rats; Rats, Inbred Lew; Receptors, Cholinergic; Severity of Illness Index

2008
Phenytoin- and cranial radiotherapy-induced toxic epidermal necrolysis treated with combination therapy: systemic steroid and intravenous immunoglobulin.
    Medical oncology (Northwood, London, England), 2012, Volume: 29, Issue:2

    Topics: Adenocarcinoma; Anti-Inflammatory Agents; Anticonvulsants; Brain Neoplasms; Combined Modality Therapy; Cranial Irradiation; Drug Therapy, Combination; Free Radical Scavengers; Humans; Immunoglobulins, Intravenous; Male; Methylprednisolone; Middle Aged; Pentoxifylline; Phenytoin; Prognosis; Rectal Neoplasms; Stevens-Johnson Syndrome

2012
Effect of pentoxifylline on histopathological changes in steroid-induced osteonecrosis of femoral head: experimental study in chicken.
    International orthopaedics, 2012, Volume: 36, Issue:7

    Topics: Adipogenesis; Animals; Bone Marrow Cells; Chickens; Disease Models, Animal; Femur Head; Femur Head Necrosis; Glucocorticoids; Injections, Intramuscular; Male; Methylprednisolone; Necrosis; Pentoxifylline; Vasodilator Agents

2012
Pentoxifylline and Methylprednisolone Additively Alleviate Kidney Failure and Prolong Survival of Rats after Renal Warm Ischemia-Reperfusion.
    International journal of molecular sciences, 2018, Jan-11, Volume: 19, Issue:1

    Topics: Acute Kidney Injury; Animals; Glucocorticoids; Kidney; Male; Methylprednisolone; Pentoxifylline; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Vasodilator Agents

2018