methylprednisolone and paclitaxel

methylprednisolone has been researched along with paclitaxel in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (14.71)18.2507
2000's19 (55.88)29.6817
2010's10 (29.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Thakker, DR; Troutman, MD1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Chen, X; Lin, X; Skolnik, S; Wang, J1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dirix, L; Kaye, S; Prove, A; Schrijvers, D; van Oosterom, A; Vonck, I; Wanders, J1
Adelstein, EH; Haghighi, SS; Madsen, R; Perez-Espejo, MA1
Awada, A; Bontenbal, M; Coleman, R; Klijn, J; Mauriac, L; Nooij, M; Paridaens, R; Piccart, MJ; Selleslags, J; Van Glabbeke, M; Van Vreckem, A1
Alvinerie, P; Canal, P; Chatelut, E; Cros, S; Dezeuse, A; Dubois, J; Monsarrat, B; Roche, H; Royer, I; Wright, M1
Bachier, C; Cabanillas, F; Hagemeister, FB; McLaughlin, P; Preti, H; Rodriguez, MA; Romaguera, JE; Sarris, AH; Weber, D; Younes, A1
Bartholomeus, S; Bleiberg, H; Brassinne, C; Cazenave, I; de Valeriola, D; Hennebert, P; Kerger, J; Kusenda, Z; Lefresne-Soulas, F; Piccart, M; Selleslags, J; Van Den Neste, E; Wythouck, H1
Kearney, K; Myers, JS1
Gordon, RJ; Osterwalder, B; Planting, AS; Pronk, LC; Reigner, B; Sparreboom, A; Twelves, C; Vasey, P; Verweij, J1
Bruno, R; De Bruijn, E; Highley, M; Locci-Tonelli, D; Pronk, L; Schrijvers, D; Van Oosterom, AT; Verweij, J1
Balaguer-Martínez, JV; Castillo-Pallarés, FJ; Ferrer Albiach, C; Pallardó-Calatayud, J; Romero-de-Avila, C; Ruiz Hernández, G1
Mileshkin, L; Prince, HM; Rischin, D; Zimet, A1
Perng, RP; Wang, GS; Yang, KY1
Beer, TM; Hayes-Lattin, BM; Henner, WD; Kovach, PA1
Abebe, L; Bhagwati, N; Jain, D; Marcoullis, G; Talusan, R; Wiernik, PH1
Achard, JL; Amat, S; Body, G; Bougnoux, P; Chollet, P; Curé, H; Dauplat, J; Fétissof, F; Kwiatkowski, F; Penault-Llorca, F1
Ardavanis, A; Baziotis, N; Gerasimidis, G; Rigatos, G; Tryfonopoulos, D; Yiotis, I1
Hiraki, A; Kanehiro, A; Kiura, K; Kozuki, T; Suzaki, N; Tabata, M; Takigawa, N; Tanimoto, M; Tanimoto, Y; Ueoka, H1
Gao, LL; Huang, XE; Zhang, Q1
Funada, Y; Itoh, T; Kobayashi, K; Kotani, Y; Nagai, H; Nagano, T; Nakata, K; Nishimura, Y; Sakashita, A; Tomita, N1
Lu, Y; Park, K; Sturek, M1
Chargari, C; Libert, N; Magne, N; Meillan, N; Tanz, R; Vedrine, L1
Burbujo, J; Calderón-Komaromy, A; Córdoba, S; de Pablo, NP; Freites-Martínez, A; Martinez-Sánchez, D1
Clay, T; Das, A; Dean, A1

Reviews

3 review(s) available for methylprednisolone and paclitaxel

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Severe interstitial pneumonitis following high-dose cyclophosphamide, thiotepa and docetaxel: two case reports and a review of the literature.
    Bone marrow transplantation, 2001, Volume: 27, Issue:5

    Topics: Adult; Anti-Inflammatory Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Docetaxel; Female; Hematopoietic Stem Cell Transplantation; Humans; Lung Diseases, Interstitial; Methylprednisolone; Middle Aged; Paclitaxel; Taxoids; Thiotepa

2001
Chemotherapy improves thymoma-associated graft-versus-host-disease-like erythroderma.
    BMJ case reports, 2011, May-10, Volume: 2011

    Topics: Anti-Inflammatory Agents; Antineoplastic Agents; Cisplatin; Dermatitis, Exfoliative; Diagnosis, Differential; Drug Therapy, Combination; Graft vs Host Disease; Humans; Male; Methylprednisolone; Middle Aged; Paclitaxel; Skin; Thymoma; Thymus Neoplasms

2011

Trials

9 trial(s) available for methylprednisolone and paclitaxel

ArticleYear
Coping with toxicities of docetaxel (Taxotere).
    Annals of oncology : official journal of the European Society for Medical Oncology, 1993, Volume: 4, Issue:7

    Topics: Antineoplastic Agents, Phytogenic; Cetirizine; Docetaxel; Drug Hypersensitivity; Edema; Humans; Ketotifen; Methylprednisolone; Paclitaxel; Skin Diseases; Taxoids

1993
The effects of taxol, methylprednisolone, and 4-aminopyridine in compressive spinal cord injury: a qualitative experimental study.
    Surgical neurology, 1996, Volume: 46, Issue:4

    Topics: 4-Aminopyridine; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Dose-Response Relationship, Drug; Evoked Potentials, Somatosensory; Male; Methylprednisolone; Microtubules; Motor Skills; Paclitaxel; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries

1996
Corticosteroids significantly delay the onset of docetaxel-induced fluid retention: final results of a randomized study of the European Organization for Research and Treatment of Cancer Investigational Drug Branch for Breast Cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997, Volume: 15, Issue:9

    Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Body Fluids; Breast Neoplasms; Cetirizine; Docetaxel; Drug Administration Schedule; Drug Eruptions; Edema; Europe; Female; Histamine H1 Antagonists; Humans; Methylprednisolone; Middle Aged; Paclitaxel; Pleural Effusion; Severity of Illness Index; Skin; Taxoids; Treatment Outcome; Water-Electrolyte Imbalance

1997
Ninety-six-hour paclitaxel infusion with mitoxantrone and ifosfamide/mesna and consolidation with ESHAP for refractory and relapsed non-Hodgkin's lymphoma.
    Leukemia & lymphoma, 1998, Volume: 32, Issue:1-2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cytarabine; Disease-Free Survival; Etoposide; Female; Humans; Ifosfamide; Lymphoma, Non-Hodgkin; Male; Mesna; Methylprednisolone; Middle Aged; Mitoxantrone; Paclitaxel; Prospective Studies; Recurrence; Remission Induction; Survival Rate; Treatment Outcome

1998
A phase I and pharmacokinetic study of docetaxel administered in combination with continuous intravenous infusion of 5-fluorouracil in patients with advanced solid tumors.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Diarrhea; Docetaxel; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Infusions, Intravenous; Male; Methylprednisolone; Middle Aged; Neoplasms; Neutropenia; Paclitaxel; Taxoids

2000
A phase I and pharmacokinetic study of the combination of capecitabine and docetaxel in patients with advanced solid tumours.
    British journal of cancer, 2000, Volume: 83, Issue:1

    Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Asthenia; Biotransformation; Capecitabine; Carboxylic Ester Hydrolases; Deamination; Deoxycytidine; Dexamethasone; Docetaxel; Drug Administration Schedule; Female; Fever; Fluorouracil; Gastrointestinal Diseases; Humans; Infusions, Intravenous; Liver; Male; Maximum Tolerated Dose; Methylprednisolone; Middle Aged; Neoplasms; Neutropenia; Paclitaxel; Paronychia; Prodrugs; Remission Induction; Taxoids; Treatment Outcome

2000
Pharmacokinetics of ifosfamide are changed by combination with docetaxel: results of a phase I pharmacologic study.
    American journal of clinical oncology, 2000, Volume: 23, Issue:4

    Topics: Adult; Anti-Inflammatory Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Chromatography, High Pressure Liquid; Confidence Intervals; Dexamethasone; Docetaxel; Drug Administration Schedule; Drug Interactions; Female; Gas Chromatography-Mass Spectrometry; Glucocorticoids; Half-Life; Humans; Ifosfamide; Infusions, Intravenous; Male; Metabolic Clearance Rate; Methylprednisolone; Middle Aged; Paclitaxel; Taxoids

2000
Neoadjuvant docetaxel for operable breast cancer induces a high pathological response and breast-conservation rate.
    British journal of cancer, 2003, May-06, Volume: 88, Issue:9

    Topics: Antineoplastic Agents, Phytogenic; Blood Cell Count; Breast Neoplasms; Chemotherapy, Adjuvant; Docetaxel; Drug Administration Schedule; Female; Humans; Injections, Intravenous; Methylprednisolone; Neoplasm Invasiveness; Neoplasm Staging; Paclitaxel; Receptors, Estrogen; Receptors, Progesterone; Recurrence; Survival Analysis; Taxoids; Treatment Outcome

2003
A clinical study on the premedication of paclitaxel liposome in the treatment of solid tumors.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2009, Volume: 63, Issue:8

    Topics: Administration, Oral; Adult; Aged; Anthracyclines; Antiemetics; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Dexamethasone; Drug Administration Schedule; Female; Fluorouracil; Glucocorticoids; Granisetron; Humans; Infusions, Intravenous; Liposomes; Male; Methylprednisolone; Middle Aged; Neoplasms; Paclitaxel; Premedication; Treatment Outcome; Young Adult

2009

Other Studies

22 other study(ies) available for methylprednisolone and paclitaxel

ArticleYear
Novel experimental parameters to quantify the modulation of absorptive and secretory transport of compounds by P-glycoprotein in cell culture models of intestinal epithelium.
    Pharmaceutical research, 2003, Volume: 20, Issue:8

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blotting, Western; Cells, Cultured; Diffusion; Humans; Intestinal Absorption; Intestinal Mucosa; Models, Biological; Permeability; Pharmaceutical Preparations; Pharmacokinetics

2003
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Modification of paclitaxel metabolism in a cancer patient by induction of cytochrome P450 3A4.
    Drug metabolism and disposition: the biological fate of chemicals, 1998, Volume: 26, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Bile; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Humans; Hydroxylation; Methylprednisolone; Middle Aged; Mixed Function Oxygenases; Paclitaxel

1998
Emergency. Chemotherapy-induced hypersensitivity reaction.
    The American journal of nursing, 2000, Volume: 100, Issue:4

    Topics: Anti-Allergic Agents; Antineoplastic Agents, Phytogenic; Diphenhydramine; Drug Hypersensitivity; Emergencies; Female; Humans; Methylprednisolone; Middle Aged; Ovarian Neoplasms; Paclitaxel

2000
[Is it useful to perform a (67)gallium scintigraphy in the follow-up of patients with gastric lymphoma?].
    Revista espanola de medicina nuclear, 2001, Volume: 20, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Fatal Outcome; Follow-Up Studies; Gallium Radioisotopes; Gastrectomy; Gastroscopy; Humans; Ifosfamide; Lymphoma, Large B-Cell, Diffuse; Male; Mesna; Methylprednisolone; Mitoxantrone; Neoplasm Recurrence, Local; Paclitaxel; Prednisone; Radionuclide Imaging; Radiopharmaceuticals; Radiotherapy, Adjuvant; Stomach Neoplasms; Stomach Ulcer; Tomography, X-Ray Computed; Vincristine

2001
Life-threatening hypersensitivity pneumonitis induced by docetaxel (taxotere).
    British journal of cancer, 2001, Nov-02, Volume: 85, Issue:9

    Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Cross Infection; Docetaxel; Female; Humans; Hydrocortisone; Immunosuppressive Agents; Lung Neoplasms; Male; Methylprednisolone; Paclitaxel; Pneumonia; Pneumothorax; Respiration, Artificial; Taxoids

2001
Successful treatment of metastatic hormone-refractory prostate cancer with malignant pericardial tamponade using docetaxel.
    Urology, 2002, Volume: 59, Issue:1

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cardiac Tamponade; Cisplatin; Combined Modality Therapy; Docetaxel; Humans; Male; Methylprednisolone; Middle Aged; Paclitaxel; Pericardial Effusion; Pericardiocentesis; Pleural Effusion; Prostatic Neoplasms; Taxoids

2002
Microangiopathic hemolysis refractory to plasmapheresis responding to docetaxel and cisplatin: a case report.
    Medical oncology (Northwood, London, England), 2002, Volume: 19, Issue:3

    Topics: Adenocarcinoma; Anemia, Hemolytic; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cisplatin; Docetaxel; Female; Hemolysis; Humans; Methylprednisolone; Middle Aged; Paclitaxel; Plasmapheresis; Taxoids

2002
Non-allergic nature of docetaxel-induced acute hypersensitivity reactions.
    Anti-cancer drugs, 2004, Volume: 15, Issue:6

    Topics: Administration, Oral; Adult; Blood Pressure; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Deoxycytidine; Docetaxel; Doxorubicin; Drug Hypersensitivity; Female; Gemcitabine; Histamine; Histamine Antagonists; Humans; Hypersensitivity, Immediate; Infusions, Intravenous; Male; Methylprednisolone; Middle Aged; Paclitaxel; Premedication; Serine Endopeptidases; Tachycardia; Taxoids; Time Factors; Tryptases

2004
Severe interstitial pneumonia induced by paclitaxel in a patient with adenocarcinoma of the lung.
    Acta medica Okayama, 2006, Volume: 60, Issue:5

    Topics: Adenocarcinoma; Aged; Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Fatal Outcome; Humans; Lung Diseases, Interstitial; Lung Neoplasms; Male; Methylprednisolone; Paclitaxel

2006
Microparticles produced by the hydrogel template method for sustained drug delivery.
    International journal of pharmaceutics, 2014, Jan-30, Volume: 461, Issue:1-2

    Topics: Delayed-Action Preparations; Drug Carriers; Drug Compounding; Drug Delivery Systems; Hydrogels; Lactic Acid; Methylprednisolone; Methylprednisolone Acetate; Molecular Weight; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Polyvinyl Alcohol; Risperidone; Solvents; Viscosity

2014
Successful readministration of trastuzumab after severe immune reactions in two breast cancer patients.
    Investigational new drugs, 2014, Volume: 32, Issue:3

    Topics: Adult; Anaphylaxis; Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Bronchodilator Agents; Chlorpheniramine; Female; Histamine H1 Antagonists; Humans; Ipratropium; Methylprednisolone; Middle Aged; Paclitaxel; Receptor, ErbB-2; Trastuzumab

2014
[Exudative onycholysis and acute bacterial paronychia related to BIBF-1120 and paclitaxel: response to topical therapy].
    Investigacion clinica, 2014, Volume: 55, Issue:1

    Topics: Angiogenesis Inhibitors; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Disease Susceptibility; Female; Fusidic Acid; Hand; Humans; Indoles; Methylprednisolone; Middle Aged; Onycholysis; Paclitaxel; Paronychia; Staphylococcal Skin Infections

2014
Gemcitabine-induced haemolytic uraemic syndrome in pancreatic adenocarcinoma.
    BMJ case reports, 2019, Apr-08, Volume: 12, Issue:4

    Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Deoxycytidine; Female; Gemcitabine; Glucocorticoids; Hemolytic-Uremic Syndrome; Humans; Methylprednisolone; Paclitaxel; Pancreatic Neoplasms

2019