methylprednisolone and methylprednisolone suleptanate

methylprednisolone has been researched along with methylprednisolone suleptanate in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19903 (20.00)18.7374
1990's10 (66.67)18.2507
2000's2 (13.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hashimoto, M; Hayashi, S; Nomura, Y1
Shah, JA; Weber, DJ1
Hall, ED; Yonkers, PA1
Bothwell, BE; Shah, JA; Weber, DJ1
Harasawa, Y; Hayashi, S; Nomura, S1
Hashimoto, M; Katori, M; Shinozaki, Y1
Della-Coletta, AA; Ferry, JJ; VanderLugt, JT; Weber, DJ1
Ito, M; Kojima, R; Nagamatsu, T; Suzuki, Y; Taniguchi, H1
Godard, PH; Harry, JD; Leophonte, P; Muir, JF; Racineux, JL1
Daley-Yates, PT; Parker, TJ; Wood, SA1
Brooks, CD; Daley-Yates, PT; Gregory, AJ1
Ishii, H; Mori, K; Ohtsuka, K; Ohuchi, H; Okamoto, H1
Nishimura, T; Noro, Y; Ogata, M; Tahara, T; Yamada, M1
Paggiaro, P1
Clapp, LH; Cui, Y; Tinker, A1

Reviews

1 review(s) available for methylprednisolone and methylprednisolone suleptanate

ArticleYear
Methylprednisolone suleptanate Pharmacia Corp.
    Current opinion in investigational drugs (London, England : 2000), 2000, Volume: 1, Issue:1

    Topics: Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Clinical Trials as Topic; Drugs, Investigational; Humans; Methylprednisolone; Prodrugs; Spinal Cord Injuries; Structure-Activity Relationship

2000

Trials

4 trial(s) available for methylprednisolone and methylprednisolone suleptanate

ArticleYear
Pilot study of the pharmacokinetics of methylprednisolone after single and multiple intravenous doses of methylprednisolone sodium succinate and methylprednisolone suleptanate to healthy volunteers.
    Journal of clinical pharmacology, 1994, Volume: 34, Issue:11

    Topics: Adult; Humans; Injections, Intravenous; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Pilot Projects; Prodrugs; Single-Blind Method

1994
Seventy-two hour comparison of methylprednisolone suleptanate and methylprednisolone sodium succinate in patients with acute asthma.
    The British journal of clinical practice, 1996, Volume: 50, Issue:8

    Topics: Acute Disease; Adolescent; Adult; Anti-Inflammatory Agents; Asthma; Double-Blind Method; Female; Humans; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Middle Aged; Prodrugs; Respiratory Function Tests

1996
A comparative population pharmacokinetic analysis for methylprednisolone following multiple dosing of two prodrugs in patients with acute asthma.
    British journal of clinical pharmacology, 1997, Volume: 43, Issue:6

    Topics: Area Under Curve; Asthma; Bayes Theorem; Body Weight; Chromatography, High Pressure Liquid; Double-Blind Method; Female; Glucocorticoids; Half-Life; Humans; Injections, Intravenous; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Prodrugs; Sex Factors; Smoking

1997
Pharmacokinetic and pharmacodynamic assessment of bioavailability for two prodrugs of methylprednisolone.
    British journal of clinical pharmacology, 1997, Volume: 43, Issue:6

    Topics: Adolescent; Adult; Analysis of Variance; Area Under Curve; Basophils; Biological Availability; Blood Glucose; Chromatography, High Pressure Liquid; Cross-Over Studies; Glucocorticoids; Histamine; Humans; Leukocyte Count; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Middle Aged; Prodrugs; Radioimmunoassay; Single-Blind Method; Therapeutic Equivalency

1997

Other Studies

10 other study(ies) available for methylprednisolone and methylprednisolone suleptanate

ArticleYear
Inhibitory effect of methylprednisolone suleptanate (U-67590A) on anaphylactic bronchoconstriction in guinea pigs.
    Research communications in chemical pathology and pharmacology, 1992, Volume: 75, Issue:3

    Topics: Anaphylaxis; Animals; Antigens; Asthma; Bronchial Diseases; Chromones; Constriction, Pathologic; Dose-Response Relationship, Drug; Guinea Pigs; Male; Methylprednisolone; Ovalbumin; SRS-A; Time Factors

1992
Simultaneous determination of methylprednisolone and methylprednisolone 21-[8-[methyl-(2-sulfoethyl)amino]-8-oxooctanoate] sodium salt in human urine by high-performance liquid chromatography with ultraviolet detection.
    Journal of chromatography, 1989, Nov-24, Volume: 496, Issue:2

    Topics: Adolescent; Adult; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Edetic Acid; Humans; Male; Methylprednisolone; Middle Aged; Spectrophotometry, Ultraviolet; Tetraethylammonium; Tetraethylammonium Compounds

1989
Comparison of two ester prodrugs of methylprednisolone on early neurologic recovery in a murine closed head injury model.
    Journal of neurotrauma, 1989,Fall, Volume: 6, Issue:3

    Topics: Animals; Brain Concussion; Craniocerebral Trauma; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Mice; Mice, Inbred Strains; Prodrugs

1989
High-performance liquid chromatographic determination of methylprednisolone and methylprednisolone 21-[8-[methyl-(2-sulfoethyl)amino]-8-oxoctanoate] sodium salt in human plasma.
    Journal of chromatography, 1987, Feb-20, Volume: 414, Issue:1

    Topics: Adolescent; Adult; Biological Availability; Chromatography, High Pressure Liquid; Drug Stability; Humans; Indicators and Reagents; Kinetics; Male; Methylprednisolone; Middle Aged; Spectrophotometry, Ultraviolet

1987
Antishock effect of U-67,590A, methylprednisolone suleptanate, associated with restoration of lowered vascular reactivity in endotoxemic rats.
    Journal of cardiovascular pharmacology, 1993, Volume: 22, Issue:4

    Topics: Animals; Aorta; Blood Pressure; Endotoxins; Escherichia coli; In Vitro Techniques; Male; Methylprednisolone; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Potassium Chloride; Prodrugs; Rats; Rats, Sprague-Dawley; Shock, Septic; Survival Rate

1993
Immediate inhibitory effect of methylprednisolone suleptanate (U-67590A) on antigen-induced cutaneous and airway anaphylactic responses in guinea-pigs.
    British journal of pharmacology, 1993, Volume: 108, Issue:3

    Topics: Airway Resistance; Anaphylaxis; Animals; Bradykinin; Capillary Permeability; Cycloheximide; Dexamethasone; Guinea Pigs; Histamine; Histamine Release; Immunoglobulin E; Immunoglobulin G; In Vitro Techniques; Male; Methylprednisolone; Methylprednisolone Hemisuccinate; Passive Cutaneous Anaphylaxis; Receptors, Glucocorticoid; Respiratory System; Skin

1993
Marked antinephritic action and less adverse effects of methylprednisolone suleptanate by intermittent administration in rats.
    Japanese journal of pharmacology, 1994, Volume: 64, Issue:2

    Topics: Adrenal Glands; Animals; Antibodies; Basement Membrane; Body Weight; Cholesterol; Corticosterone; Creatinine; Drug Administration Schedule; Glomerular Mesangium; Glomerulonephritis; Kidney Glomerulus; Macrophages; Male; Methylprednisolone; Monocytes; Organ Size; Proteinuria; Rats; Rats, Sprague-Dawley

1994
Effect of ionic strength on solution stability of PNU-67590A, a micellar prodrug of methylprednisolone.
    Pharmaceutical research, 1997, Volume: 14, Issue:9

    Topics: Drug Stability; Ions; Methylprednisolone; Prodrugs

1997
Photodegradation products of methylprednisolone suleptanate in aqueous solution--evidence of a bicyclo[3.1.0]hex-3-en-2-one intermediate.
    Journal of pharmaceutical sciences, 1998, Volume: 87, Issue:1

    Topics: Drug Stability; Magnetic Resonance Spectroscopy; Methylprednisolone; Photolysis; Prodrugs; Solutions; Water

1998
Different molecular sites of action for the KATP channel inhibitors, PNU-99963 and PNU-37883A.
    British journal of pharmacology, 2003, Volume: 139, Issue:1

    Topics: Adenosine Triphosphate; Aminopyridines; ATP-Binding Cassette Transporters; Cell Line; Cloning, Molecular; Dose-Response Relationship, Drug; Guanidines; Humans; Islets of Langerhans; Membrane Potentials; Methylprednisolone; Muscle, Smooth; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Subunits; Receptors, Drug; Sulfonylurea Receptors; Transfection

2003