methylprednisolone has been researched along with fluorouracil in 39 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (30.77) | 18.7374 |
| 1990's | 9 (23.08) | 18.2507 |
| 2000's | 10 (25.64) | 29.6817 |
| 2010's | 7 (17.95) | 24.3611 |
| 2020's | 1 (2.56) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Braunschweiger, PG; Schiffer, LM; Stragand, JJ | 1 |
| Riedler, L | 1 |
| Casado, A; Diaz-Rubio, E; Dominguez, S; Martin, M; Sastre, J | 1 |
| Cass, Y; Edelmann, DZ; Gez, E; Strauss, N; Vitzhaki, N | 1 |
| Havsteen, H; Kjaer, M | 1 |
| Bastit, P; Bonneterre, J; Cappelaere, P; Chevrier, A; Fargeot, P; Geyer, G; Kerbrat, P; Metz, R; Roche, H; Tubiana-Hulin, M | 1 |
| Barriga, JJ; Diaz-Rubio, E; Gonzalez-Larriba, JL; Martin, M; Rosell, R; Valerdi, JJ | 1 |
| Baldini, E; Bruzzi, P; Campora, E; Chiara, S; Rosso, R; Rubagotti, A; Sertoli, MR | 1 |
| Guillén Lloveria, G; Mayordomo Cámara, JJ; Sáenz Cusi, A; Sáez Martínez, MJ; Tres Sánchez, A | 1 |
| Biran, S; Cass, Y; Gera, C; Gez, E; Nathan, S; Ochayon, L; Rubello, E; Sulkes, A | 1 |
| Bruzzi, P; Campora, E; Chiara, S; Lionetto, R; Rosso, R | 1 |
| Asselain, B; Coutant, M; Dorval, T; Garcia-Giralt, E; Jouve, M; Magdelenat, H; Palangie, T; Pouillart, P | 1 |
| Ballatori, E; Basurto, C; del Favero, A; Minotti, V; Roila, F; Tonato, M | 2 |
| Gordon, MY; Greaves, MF; Riley, GP | 1 |
| Bruzzi, P; Campora, E; Chiara, S; Rosso, R; Scarsi, P | 1 |
| Kummer, D | 1 |
| Horton, J; Hosley, HF; Olson, KB | 1 |
| Braunschweiger, PG; Schiffer, LM; Ting, HL | 1 |
| Fujishima, H; Hisano, C; Masumoto, N; Nakamura, M; Nakano, S; Niho, Y; Okuma, K | 1 |
| Dreger, P; Glass, B; Kuse, R; Löffler, H; Schmitz, N; Schoch, R; Sonnen, R; Uharek, L; von Neuhoff, N | 1 |
| Bartholomeus, S; Bleiberg, H; Brassinne, C; Cazenave, I; de Valeriola, D; Hennebert, P; Kerger, J; Kusenda, Z; Lefresne-Soulas, F; Piccart, M; Selleslags, J; Van Den Neste, E; Wythouck, H | 1 |
| Gordon, RJ; Osterwalder, B; Planting, AS; Pronk, LC; Reigner, B; Sparreboom, A; Twelves, C; Vasey, P; Verweij, J | 1 |
| Cho, KH; Choi, SM; Kim, BC; Kim, MK; Lee, SH; Yang, YS | 1 |
| Gao, LL; Huang, XE; Zhang, Q | 1 |
| Gauthier-Hazan, N; Lemperle, G | 1 |
| Abe, T; Ando, M; Kato, T; Nakashima, H; Shindo, J; Shiraki, A; Yamamoto, K; Yukita, Y | 1 |
| Gilbar, PJ; Grewal, GD; Holcombe, DJ; Raina, AJ | 1 |
3 review(s) available for methylprednisolone and fluorouracil
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Foreign body granulomas after all injectable dermal fillers: part 2. Treatment options.
Topics: Anesthetics, Local; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Betamethasone; Dermis; Drug Therapy, Combination; Female; Fluorouracil; Granuloma, Foreign-Body; Humans; Injections; Lidocaine; Methylprednisolone; Minocycline; Triamcinolone | 2009 |
[A case of irinotecan or panitumumab-induced interstitial pneumonia successfully treated by steroid pulse therapy].
Topics: Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Lung Diseases, Interstitial; Male; Methylprednisolone; Middle Aged; Organoplatinum Compounds; Panitumumab; Tomography, X-Ray Computed | 2012 |
18 trial(s) available for methylprednisolone and fluorouracil
| Article | Year |
|---|---|
Methylprednisolone as antiemetic treatment in breast-cancer patients receiving cyclophosphamide, methotrexate, and 5-fluorouracil: a prospective, crossover, randomized blind study comparing two different dose schedules.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Double-Blind Method; Drug Administration Schedule; Female; Fluorouracil; Humans; Methotrexate; Methylprednisolone; Middle Aged; Nausea; Prospective Studies; Vomiting | 1992 |
Double-blind randomized cross-over trial comparing methylprednisolone with placebo in chemotherapy-induced nausea and vomiting: a study with special reference to efficacy parameters.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Double-Blind Method; Female; Fluorouracil; Humans; Methotrexate; Methylprednisolone; Middle Aged; Nausea; Placebos; Vomiting | 1991 |
Tetracosactrin vs. methylprednisolone in the prevention of emesis in patients receiving FEC regimen for breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cosyntropin; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Humans; Methylprednisolone; Nausea; Quality of Life; Vomiting | 1991 |
The antiemetic efficacy of thiethylperazine and methylprednisolone versus thiethylperazine and placebo in breast cancer patients treated with adjuvant chemotherapy (fluorouracil, doxorubicin and cyclophosphamide). A randomized, double-blind, cross-over tr
Topics: Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Double-Blind Method; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methylprednisolone; Middle Aged; Thiethylperazine | 1991 |
Double-blind randomized trial of lorazepam versus placebo with methylprednisolone for control of emesis due to non-cisplatin containing chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Double-Blind Method; Drug Therapy, Combination; Epirubicin; Female; Fluorouracil; Humans; Injections, Intramuscular; Injections, Intravenous; Lorazepam; Methotrexate; Methylprednisolone; Middle Aged; Vomiting | 1990 |
[Antiemetic treatments associated with antineoplastic chemotherapy].
Topics: Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lorazepam; Methylprednisolone; Metoclopramide; Vincristine; Vomiting | 1990 |
Methylprednisolone versus metoclopramide as antiemetic treatment in patients receiving adjuvant cyclophosphamide, methotrexate, 5-fluorouracil (CMF) chemotherapy: a randomized crossover blind study.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Methylprednisolone; Metoclopramide; Middle Aged; Randomized Controlled Trials as Topic; Vomiting | 1989 |
Methylprednisolone for the control of CMF-induced emesis.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Methotrexate; Methylprednisolone; Middle Aged; Random Allocation; Vomiting | 1987 |
[Metastatic breast cancer. Modality of association of chemotherapy and hormonotherapy. Results of a controlled trial].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Synergism; Female; Fluorouracil; Humans; Methylprednisolone; Middle Aged; Neoplasm Metastasis; Random Allocation; Tamoxifen | 1987 |
Double-blind controlled trial of the antiemetic efficacy and toxicity of methylprednisolone (MP), metoclopramide (MTC) and domperidone (DMP) in breast cancer patients treated with i.v. CMF.
Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Domperidone; Double-Blind Method; Female; Fluorouracil; Humans; Methotrexate; Methylprednisolone; Metoclopramide; Middle Aged; Nausea; Vomiting | 1987 |
Methylprednisolone versus metoclopramide for prevention of nausea and vomiting in breast cancer patients treated with intravenous cyclophosphamide methotrexate 5-fluorouracil: a double-blind randomized study.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Double-Blind Method; Female; Fluorouracil; Humans; Methotrexate; Methylprednisolone; Metoclopramide; Middle Aged; Nausea; Random Allocation; Vomiting | 1988 |
The antiemetic efficacy of methylprednisolone compared with metoclopramide in outpatients receiving adjuvant CMF chemotherapy for breast cancer: a randomized trial.
Topics: Adult; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; Methylprednisolone; Metoclopramide; Middle Aged; Random Allocation | 1985 |
Corticosteroids and fluorouracil toxicity.
Topics: Bone Marrow; Clinical Trials as Topic; Diarrhea; Digestive System; Fluorouracil; Humans; Injections, Intravenous; Leukopenia; Methylprednisolone; Middle Aged; Neoplasms; Placebos; Stomatitis; Thrombocytopenia | 1966 |
[Comparative trial of granisetron alone and granisetron plus methylprednisolone for prevention of nausea and vomiting during cancer chemotherapy].
Topics: Adult; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cross-Over Studies; Drug Therapy, Combination; Female; Fluorouracil; Granisetron; Humans; Leucovorin; Lung Neoplasms; Male; Methylprednisolone; Middle Aged; Nausea; Vomiting | 1996 |
Early stem cell transplantation for chronic lymphocytic leukaemia: a chance for cure?
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Chlorambucil; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Dexamethasone; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Female; Fluorouracil; Follow-Up Studies; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Humans; Hydrocortisone; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Melphalan; Methotrexate; Methylprednisolone; Middle Aged; Mitomycins; Prednisone; Prospective Studies; Treatment Outcome; Vincristine | 1998 |
A phase I and pharmacokinetic study of docetaxel administered in combination with continuous intravenous infusion of 5-fluorouracil in patients with advanced solid tumors.
Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Diarrhea; Docetaxel; Dose-Response Relationship, Drug; Female; Fluorouracil; Humans; Infusions, Intravenous; Male; Methylprednisolone; Middle Aged; Neoplasms; Neutropenia; Paclitaxel; Taxoids | 2000 |
A phase I and pharmacokinetic study of the combination of capecitabine and docetaxel in patients with advanced solid tumours.
Topics: Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Asthenia; Biotransformation; Capecitabine; Carboxylic Ester Hydrolases; Deamination; Deoxycytidine; Dexamethasone; Docetaxel; Drug Administration Schedule; Female; Fever; Fluorouracil; Gastrointestinal Diseases; Humans; Infusions, Intravenous; Liver; Male; Maximum Tolerated Dose; Methylprednisolone; Middle Aged; Neoplasms; Neutropenia; Paclitaxel; Paronychia; Prodrugs; Remission Induction; Taxoids; Treatment Outcome | 2000 |
A clinical study on the premedication of paclitaxel liposome in the treatment of solid tumors.
Topics: Administration, Oral; Adult; Aged; Anthracyclines; Antiemetics; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Dexamethasone; Drug Administration Schedule; Female; Fluorouracil; Glucocorticoids; Granisetron; Humans; Infusions, Intravenous; Liposomes; Male; Methylprednisolone; Middle Aged; Neoplasms; Paclitaxel; Premedication; Treatment Outcome; Young Adult | 2009 |
18 other study(ies) available for methylprednisolone and fluorouracil
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Effect of methylprednisolone on cell proliferation in C3H/HeJ spontaneous mammary tumors.
Topics: Animals; Cell Cycle; Cell Division; Drug Therapy, Combination; Female; Fluorouracil; Kinetics; Mammary Neoplasms, Experimental; Methotrexate; Methylprednisolone; Mice; Mice, Inbred C3H | 1978 |
[Polychemotherapy of the advanced and metastasizing carcinoma of the breast].
Topics: Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Methylprednisolone; Neoplasm Metastasis; Remission, Spontaneous; Time Factors; Vinblastine | 1976 |
Progressive loss of antiemetic efficacy during subsequent courses of chemotherapy.
Topics: Adult; Aged; Amitriptyline; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methylprednisolone; Middle Aged; Nausea; Thiethylperazine; Vomiting | 1992 |
Plastic-adherent progenitor cells in human bone marrow.
Topics: Bone Marrow Cells; Cell Adhesion; Fluorouracil; Growth Substances; Hematopoietic Stem Cells; Histocytochemistry; Humans; Methylprednisolone; Phenotype; Plastics | 1987 |
[Effects of cytostatics and x-rays on nucleic acid metabolism of solid, malignant tumors in vitro].
Topics: Adenine; Animals; Antineoplastic Agents; Carbon Isotopes; Dactinomycin; Depression, Chemical; DNA, Neoplasm; Estriol; Fluorouracil; Formates; Glycine; Hypoxanthines; In Vitro Techniques; Leucine; Mercaptopurine; Methotrexate; Methylprednisolone; Neoplasm Proteins; Neoplasms, Experimental; Nucleosides; Orotic Acid; Radiation Effects; RNA, Neoplasm; Testosterone; Thymidine; Triaziquone; Uracil; Uridine | 1970 |
Receptor-mediated antiproliferative effects of corticosteroids in Lewis lung tumors.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Dexamethasone; Dose-Response Relationship, Drug; Fluorouracil; Lung Neoplasms; Male; Methylprednisolone; Mice; Mice, Inbred C57BL; Mitosis; Receptors, Glucocorticoid; Receptors, Steroid; Triamcinolone Acetonide; Vincristine | 1984 |
5-fluorouracil-induced leukoencephalopathy in patients with breast cancer.
Topics: Adenocarcinoma, Mucinous; Adult; Anti-Inflammatory Agents; Antineoplastic Agents; Brain; Breast Neoplasms; Carcinoma, Ductal, Breast; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Glucocorticoids; Humans; Magnetic Resonance Imaging; Methylprednisolone; Middle Aged; Nervous System Diseases; Prednisolone; Radiography | 2001 |
Optic neuritis induced by 5-fluorouracil chemotherapy: Case report and review of the literature.
Topics: Administration, Intravenous; Antineoplastic Agents; Colorectal Neoplasms; Fluorouracil; Glucocorticoids; Headache; Humans; Male; Methylprednisolone; Middle Aged; Neoplasm Staging; Optic Neuritis; Treatment Outcome; Vision Disorders | 2020 |