methylphosphonic acid has been researched along with oligonucleotides in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (14.29) | 18.7374 |
| 1990's | 9 (42.86) | 18.2507 |
| 2000's | 8 (38.10) | 29.6817 |
| 2010's | 1 (4.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Amirkhanov, NV; Levina, AS; Zarytova, VF | 1 |
| Colvin, OM; Hausheer, FH; Saxe, JD; Singh, UC; T'su, PO | 1 |
| Tidd, DM; Warenius, HM | 1 |
| de Vroom, E; Dreef, CE; Marugg, JE; Tromp, M; van Boom, JH; van der Marel, GA | 1 |
| Agris, CH; Blandin, M; Miller, PS; Murakami, A; Reddy, PM; Spitz, SA; Ts'o, PO | 1 |
| Cushman, CD; Kang, H; Kean, JM; Leonard, TE; Miller, PS | 1 |
| Avrutskaya, AV; Brouwer, KL; Hughes, JA; Juliano, RL; Wickstrom, E | 1 |
| Agrawal, S; Galbraith, W; Tang, J; Temsamani, J | 1 |
| Andreeff, M; Kleine, HD; Lopez-Berestein, G; Tari, AM | 1 |
| Arnold, LJ; Beck, TA; Daily, WJ; Hogrefe, RI; Jaeger, JA; Klem, RE; Knowles, SK; Marvin, WB; Reynolds, MA; Riley, TA; Schwartz, DA; Vaghefi, MM | 1 |
| Maher, LJ; Rodrigues, PD; Strauss-Soukup, JK | 1 |
| Boulmé, F; Freund, F; Gryaznov, S; Litvak, S; Moreau, S; Nielsen, PE; Toulmé, JJ | 1 |
| Disney, MD; Testa, SM; Turner, DH | 1 |
| Gorin, AA; Kosikov, KM; Lu, XJ; Manning, GS; Olson, WK | 1 |
| Dahl, BM; Dahl, O; Lauritsen, A; Vester, B; Wengel, J | 1 |
| Harrington, L; Oulton, R | 1 |
| Claeboe, CD; Eisenhauer, BM; Gao, R; Hecht, SM | 1 |
| Eoff, RL; Raney, KD; Spurling, TL | 1 |
| Lacroix, L; Mergny, JL; Saccà, B | 1 |
| Monn, ST; Schürch, S | 1 |
| Kostov, O; Páv, O; Rosenberg, I | 1 |
1 review(s) available for methylphosphonic acid and oligonucleotides
| Article | Year |
|---|---|
Pharmacokinetics of antisense oligonucleotides.
Topics: Animals; Antiviral Agents; Base Sequence; Clinical Trials as Topic; Esters; Humans; Molecular Sequence Data; Oligodeoxyribonucleotides, Antisense; Oligonucleotides; Oligonucleotides, Antisense; Organophosphorus Compounds; Thionucleotides; Tissue Distribution | 1995 |
20 other study(ies) available for methylphosphonic acid and oligonucleotides
| Article | Year |
|---|---|
[Reactivity of oligonucleotide derivatives, containing methylphosphonate groups. VI. Increase in the effectiveness of directed action of alkylating derivatives of oligonucleotide methylphosphonate analogs on nucleic acids in the presence of effectors--3',
Topics: Alkylating Agents; Base Sequence; DNA; Electrophoresis, Polyacrylamide Gel; Molecular Sequence Data; Oligonucleotides; Organophosphorus Compounds; Phenazines; Temperature | 1990 |
Can oligonucleoside methylphosphonates form a stable triplet with a double DNA helix?
Topics: Chemical Phenomena; Chemistry; Computer Simulation; DNA; Models, Molecular; Oligonucleotides; Organophosphorus Compounds | 1990 |
Partial protection of oncogene, anti-sense oligodeoxynucleotides against serum nuclease degradation using terminal methylphosphonate groups.
Topics: Drug Stability; Genes, ras; Oligonucleotides; Oligonucleotides, Antisense; Organophosphorus Compounds; Phosphoric Diester Hydrolases | 1989 |
Synthesis of nucleic acid methylphosphonates via the 1-hydroxybenzotriazole phosphotriester approach.
Topics: Chemical Phenomena; Chemistry; Dinucleoside Phosphates; Indicators and Reagents; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Nucleotides, Cyclic; Oligonucleotides; Organophosphorus Compounds; Phosphorylation; Stereoisomerism; Triazoles | 1986 |
Use of methylphosphonic dichloride for the synthesis of oligonucleoside methylphosphonates.
Topics: Indicators and Reagents; Methods; Oligonucleotides; Organophosphorus Compounds; Structure-Activity Relationship | 1983 |
Interactions of oligonucleotide analogs containing methylphosphonate internucleotide linkages and 2'-O-methylribonucleosides.
Topics: Adenosine; Base Sequence; DNA; Drug Stability; Guanosine; Macromolecular Substances; Molecular Sequence Data; Oligonucleotides; Organophosphorus Compounds; RNA; Stereoisomerism; Temperature | 1994 |
Radiolabeling of methylphosphonate and phosphorothioate oligonucleotides and evaluation of their transport in everted rat jejunum sacs.
Topics: Alkylation; Animals; Biological Transport; Formaldehyde; Isotope Labeling; Jejunum; Oligonucleotides; Organophosphorus Compounds; Radioligand Assay; Rats; Rats, Sprague-Dawley; Time Factors | 1995 |
Cellular uptake and localization of liposomal-methylphosphonate oligodeoxynucleotides.
Topics: Drug Carriers; HL-60 Cells; Humans; Liposomes; Oligonucleotides; Organophosphorus Compounds; Tumor Cells, Cultured | 1996 |
Synthesis and thermodynamics of oligonucleotides containing chirally pure R(P) methylphosphonate linkages.
Topics: Chromatography, High Pressure Liquid; Isomerism; Magnetic Resonance Spectroscopy; Oligonucleotides; Organophosphorus Compounds | 1996 |
Effect of base composition on DNA bending by phosphate neutralization.
Topics: Base Composition; Binding Sites; DNA; Electrophoresis, Polyacrylamide Gel; Nucleic Acid Conformation; Oligonucleotides; Organophosphorus Compounds; Phosphates; Thermodynamics | 1998 |
Modified (PNA, 2'-O-methyl and phosphoramidate) anti-TAR antisense oligonucleotides as strong and specific inhibitors of in vitro HIV-1 reverse transcription.
Topics: Anti-HIV Agents; Base Sequence; Electrophoresis, Polyacrylamide Gel; HIV Long Terminal Repeat; HIV Reverse Transcriptase; Molecular Sequence Data; Nucleic Acid Heteroduplexes; Oligodeoxyribonucleotides; Oligonucleotides; Oligonucleotides, Antisense; Oligoribonucleotides; Organophosphorus Compounds; Peptide Nucleic Acids; Thionucleotides | 1998 |
Targeting a Pneumocystis carinii group I intron with methylphosphonate oligonucleotides: backbone charge is not required for binding or reactivity.
Topics: Binding Sites; Introns; Kinetics; Nucleic Acid Conformation; Nucleic Acid Hybridization; Oligonucleotides; Organophosphorus Compounds; Pneumocystis; RNA Precursors; RNA Splicing; RNA, Catalytic; RNA, Ribosomal; Stereoisomerism; Thermodynamics | 2000 |
Bending of DNA by asymmetric charge neutralization: all-atom energy simulations.
Topics: DNA; Models, Chemical; Models, Molecular; Nucleic Acid Conformation; Oligonucleotides; Organophosphates; Organophosphorus Compounds; Stereoisomerism | 2002 |
Methylphosphonate LNA: a locked nucleic acid with a methylphosphonate linkage.
Topics: DNA; DNA, Single-Stranded; Enzyme Inhibitors; Exonucleases; Indicators and Reagents; Oligonucleotides; Organophosphorus Compounds; Phosphoric Diester Hydrolases; RNA | 2003 |
A human telomerase-associated nuclease.
Topics: Exodeoxyribonucleases; Humans; Oligonucleotides; Organophosphorus Compounds; Substrate Specificity; Telomerase; Templates, Genetic | 2004 |
Identification of specific nonbridging phosphate oxygens important for DNA cleavage by human topoisomerase I.
Topics: Base Pairing; Base Sequence; DNA; DNA Topoisomerases, Type I; Humans; Hydrogen Bonding; Models, Molecular; Molecular Structure; Oligonucleotides; Organophosphorus Compounds; Oxygen | 2004 |
Chemically modified DNA substrates implicate the importance of electrostatic interactions for DNA unwinding by Dda helicase.
Topics: Bacteriophage T4; Catalysis; DNA Helicases; DNA, Single-Stranded; DNA, Viral; Electrophoresis, Polyacrylamide Gel; Enzyme Stability; Hot Temperature; Kinetics; Oligonucleotides; Organophosphorus Compounds; Peptide Nucleic Acids; Static Electricity; Substrate Specificity; Viral Proteins | 2005 |
The effect of chemical modifications on the thermal stability of different G-quadruplex-forming oligonucleotides.
Topics: DNA; G-Quadruplexes; Guanine; Humans; Hydrogen Bonding; Nucleic Acid Conformation; Nucleic Acid Denaturation; Oligonucleotides; Organophosphorus Compounds; Spectrophotometry, Ultraviolet; Telomere; Thermodynamics; Thionucleotides | 2005 |
New aspects of the fragmentation mechanisms of unmodified and methylphosphonate-modified oligonucleotides.
Topics: Base Sequence; DNA Fingerprinting; Molecular Sequence Data; Oligonucleotides; Organophosphorus Compounds; Sequence Analysis, DNA; Spectrometry, Mass, Electrospray Ionization | 2007 |
Nucleoside-O-Methyl-(H)-Phosphinates: Novel Monomers for the Synthesis of Methylphosphonate Oligonucleotides Using H-Phosphonate Chemistry.
Topics: Oligonucleotides; Organophosphonates; Organophosphorus Compounds | 2017 |