Page last updated: 2024-08-21

methylnitrosourea and tretinoin

methylnitrosourea has been researched along with tretinoin in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199021 (55.26)18.7374
1990's11 (28.95)18.2507
2000's5 (13.16)29.6817
2010's1 (2.63)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Becci, PJ; Brown, CC; Gander, RJ; Grubbs, CJ; Henderson, WR; Moon, RC; Mullen, LT; Newton, DL; Phillips, SL; Smith, JM; Sporn, MB; Thompson, HJ1
Richelo, BN; Tannenbaum, M; Tannenbaum, S; Trown, PW1
Dean, RJ; Feeser, D; Smith, JM; Sporn, MB; Ward, JM; Wenk, ML1
Brown, CC; Smith, JM; Sporn, MB; Springer, S; Squire, RA; Wenk, ML2
Detrisac, CJ; Kelloff, GJ; Mehta, RG; Moon, RC; Ratko, TA1
Bhat, PV; Doskas, C; Lacroix, A1
Detrisac, CJ; Dinger, NM; Kelloff, GJ; Moon, RC; Ratko, TA; Thomas, CF1
Dinger, NM; Mehta, RG; Moon, RC; Nomides, CT; Pritchard, JF; Thomas, CF1
Dinger, NM; Dowlatshahi, K; Mehta, RG; Moon, RC; Thomas, CF1
Bhat, PV; Lacroix, A1
Banerjee, MR; Manoharan, K1
McCormick, DL; Moon, RC1
Fukamachi, H1
Katayama, S; Levenstein, MJ; Radok, P; Silverman, J; Weisburger, JH1
Cerny, WL; Mehta, RG; Moon, RC2
Aylsworth, CF; DeHoog, JV; Scieszka, KM; Welsch, CW1
Enomoto, T; Hata, S; Kanzaki, T; Kimura, S; Kusafuka, T; Miyamoto, S; Nomura, T; Shibata, K; Sobue, K; Tanaka, H1
Caldwell, JA; Dinger, N; McCormick, DL; Mehta, RG; Moon, RC; Thompson, CA1
Brown, CK; Chiusano, J; Goodrich-Smith, M; Moon, RC; Welsch, CW1
Donahoe, R; Reznik, G; Stinson, SF1
Anzano, MA; Danielpour, D; Kadomatsu, K; Smith, JM; Sporn, MB1
Anzano, MA; Brown, CC; Byers, SW; Mullen, LT; Peer, CW; Roberts, AB; Smith, JM; Sporn, MB1
Fujimoto, N; Gotoh, T; Ito, A; Okamoto, T1
Aldaz, CM; Chen, Y; McKenzie, KE; Sukumar, S1
Ashbaugh, P; Bhattacharyya, SN; Coutinho, R; Kaufman, B; Manna, B1
Faustman, EM; Seeley, MR2
Bosland, MC; Kelloff, GJ; Lubet, RA; McCormick, DL; Rao, KV; Steele, VE1
Blask, DE; Cheng, Q; Hill, SM; Myers, L; Teplitzky, SR1
Anderson, MB; Blask, DE; Cheng, Q; Collins, A; Dai, J; Dwivedi, PD; Hill, SM; Kiefer, TL; Moroz, K; Myers, L; Spriggs, LL; Teplitzky, SR; Yuan, L1
Brtko, J; Dvorcakova, M; Líska, J; Macejová, D; Mostböck, S; Scheiblhofer, S; Szabová, E; Thalhamer, J; Weiss, R; Zórad, S1
Anderson, MB; Bischoff, ED; Cheng, Q; Dai, J; Dwived, PD; Hill, SM; Kiefer, TL; Lai, L; Melancon, K; Moro, K; Nowfar, S; Teplitzky, SR; Yuan, L1
Baranová, M; Brtko, J; Krammer, B; Macejová, D; Mostböck, S; Scheiblhofer, S; Thalhamer, J; Verwanger, T; Weiss, R1
Cheng, Q; Collins, A; Dai, J; Dong, C; Hill, SM; Kiefer, TL; Lai, L; Long, S; Melancon, K; Thiyagarajah, A; Yuan, L1
Gediya, LK; Godbole, AM; Goss, PE; Hu, H; Njar, VC; Purushottamachar, P; Qi, S1
Mitchell, TJ; Nettesheim, P; Yarita, T1

Other Studies

38 other study(ies) available for methylnitrosourea and tretinoin

ArticleYear
N-(4-Hydroxyphenyl)retinamide, a new retinoid for prevention of breast cancer in the rat.
    Cancer research, 1979, Volume: 39, Issue:4

    Topics: Animals; Female; Liver; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Organ Culture Techniques; Rats; Trachea; Tretinoin; Vitamin A; Vitamin A Deficiency

1979
Effects of 13-cis and all-trans-retinoic acid on the development of bladder cancer in rats: an ultrastructural study.
    Scanning electron microscopy, 1979, Issue:3

    Topics: Animals; Cell Membrane; Female; Isomerism; Methylnitrosourea; Microscopy, Electron; Microscopy, Electron, Scanning; Nitrosourea Compounds; Rats; Structure-Activity Relationship; Tretinoin; Urinary Bladder Neoplasms

1979
Dose response to intrarectal administration of N-methyl-N-nitrosourea and histopathologic evaluation of the effect of two retinoids on colon lesions induced in rats.
    Journal of the National Cancer Institute, 1978, Volume: 60, Issue:6

    Topics: Adenocarcinoma; Administration, Oral; Animals; Colonic Neoplasms; Dose-Response Relationship, Drug; Injections; Male; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Rats, Inbred F344; Rectum; Tretinoin; Vitamin A

1978
13-cis-retinoic acid: inhibition of bladder carcinogenesis in the rat.
    Science (New York, N.Y.), 1977, Feb-04, Volume: 195, Issue:4277

    Topics: Animals; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Female; Methylnitrosourea; Neoplasms, Experimental; Rats; Tretinoin; Urinary Bladder Neoplasms; Vitamin A

1977
Histopathological evaluation of the inhibition of rat bladder carcinogenesis by 13-cis-retinoic acid.
    Cancer research, 1977, Volume: 37, Issue:8 Pt 2

    Topics: Animals; Epithelium; Female; Methylnitrosourea; Neoplasms, Experimental; Precancerous Conditions; Rats; Statistics as Topic; Tretinoin; Urinary Bladder Neoplasms; Vitamin A

1977
Inhibition of rat mammary gland chemical carcinogenesis by dietary dehydroepiandrosterone or a fluorinated analogue of dehydroepiandrosterone.
    Cancer research, 1991, Jan-15, Volume: 51, Issue:2

    Topics: Androstenes; Animals; Antineoplastic Agents; Dehydroepiandrosterone; Diet; Drug Therapy, Combination; Female; Fenretinide; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Tretinoin

1991
Inhibition of growth of established N-methyl-N-nitrosourea-induced mammary cancer in rats by retinoic acid and ovariectomy.
    Cancer research, 1990, Sep-15, Volume: 50, Issue:18

    Topics: Animals; Dose-Response Relationship, Drug; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Ovariectomy; Rats; Rats, Inbred Strains; Tretinoin; Vitamin E

1990
Chemopreventive efficacy of combined retinoid and tamoxifen treatment following surgical excision of a primary mammary cancer in female rats.
    Cancer research, 1989, Aug-15, Volume: 49, Issue:16

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Drug Evaluation, Preclinical; Female; Fenretinide; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Tamoxifen; Tretinoin

1989
Suppression of rat mammary cancer development by N-(4-hydroxyphenyl)retinamide (4-HPR) following surgical removal of first palpable tumor.
    Carcinogenesis, 1989, Volume: 10, Issue:9

    Topics: Administration, Oral; Animals; Diet; Female; Fenretinide; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Tretinoin

1989
Therapeutic effect of N-(4-hydroxyphenyl)retinamide on N-methyl-N-nitrosourea-induced rat mammary cancer.
    Cancer letters, 1989, Volume: 47, Issue:3

    Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Female; Fenretinide; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Remission Induction; Tamoxifen; Tretinoin

1989
Metabolism of retinol and retinoic acid in N-methyl-N-nitrosourea-induced mammary carcinomas in rats.
    Cancer research, 1989, Jan-01, Volume: 49, Issue:1

    Topics: Acyltransferases; Animals; Carboxylic Ester Hydrolases; Female; Liver; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Retinol O-Fatty-Acyltransferase; Tretinoin; Vitamin A

1989
beta-Carotene reduces sister chromatid exchanges induced by chemical carcinogens in mouse mammary cells in organ culture.
    Cell biology international reports, 1985, Volume: 9, Issue:9

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; beta Carotene; Carcinogens; Carotenoids; Cell Transformation, Neoplastic; Diethylnitrosamine; Female; Fenretinide; Mammary Glands, Animal; Methylnitrosourea; Mice; Organ Culture Techniques; Retinoids; Sister Chromatid Exchange; Tretinoin

1985
Retinoid-tamoxifen interaction in mammary cancer chemoprevention.
    Carcinogenesis, 1986, Volume: 7, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Dose-Response Relationship, Drug; Drug Synergism; Female; Fenretinide; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Ovariectomy; Rats; Rats, Inbred Strains; Tamoxifen; Tretinoin

1986
Acceleration of epithelial keratinization by carcinogens in fetal rat forestomach in organ culture.
    Virchows Archiv. B, Cell pathology including molecular pathology, 1984, Volume: 46, Issue:3

    Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Acetoxyacetylaminofluorene; Animals; Carcinogens; Epithelium; Gastric Mucosa; Keratins; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Methylnitrosourea; Organ Culture Techniques; Rats; Rats, Inbred F344; Stomach; Tretinoin

1984
Effect of short-term administration of N-(4-hydroxyphenyl)-all-trans-retinamide on chemically induced mammary tumors.
    Nutrition and cancer, 1983, Volume: 4, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Fenretinide; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Tretinoin

1983
Nuclear interactions of retinoic acid-binding protein in chemically induced mammary adenocarcinoma.
    The Biochemical journal, 1982, Dec-15, Volume: 208, Issue:3

    Topics: Adenocarcinoma; Animals; Binding Sites; Carrier Proteins; Cell Nucleus; Centrifugation, Density Gradient; Female; In Vitro Techniques; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasm Proteins; Rats; Rats, Inbred Strains; Receptors, Retinoic Acid; Tretinoin

1982
Retinoid feeding, hormone inhibition, and/or immune stimulation and the progression of N-methyl-N-nitrosourea-induced rat mammary carcinoma: suppression by retinoids of peptide hormone-induced tumor cell proliferation in vivo and in vitro.
    Cancer research, 1984, Volume: 44, Issue:1

    Topics: Animals; Diterpenes; DNA Replication; Female; Freund's Adjuvant; Haloperidol; Immunization; Insulin; Mammary Neoplasms, Experimental; Methylnitrosourea; Organ Culture Techniques; Prolactin; Rats; Rats, Inbred Strains; Retinyl Esters; Tretinoin; Vitamin A

1984
Antiteratogenic effects of tumor inhibitors, caffeine, antipain, and retinoic acid in mice.
    Cancer research, 1983, Volume: 43, Issue:11

    Topics: 4-Nitroquinoline-1-oxide; Animals; Antipain; Caffeine; Carcinogens; Ethylnitrosourea; Female; Fetus; Hydroxamic Acids; Methylnitrosourea; Mice; Mice, Inbred ICR; Mice, Inbred Strains; Oligopeptides; Pregnancy; Teratogens; Tretinoin; Urethane

1983
Enhanced inhibition of mammary carcinogenesis by combined treatment with N-(4-hydroxyphenyl)retinamide and ovariectomy.
    Cancer research, 1982, Volume: 42, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Diet; Female; Fenretinide; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Inbred Strains; Time Factors; Tretinoin

1982
Distribution of retinoic acid-binding proteins in normal and neoplastic mammary tissues.
    Cancer research, 1980, Volume: 40, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Binding Sites; Binding, Competitive; Cytosol; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Retinol-Binding Proteins; Tretinoin

1980
Synergistic effect of chronic prolactin suppression and retinoid treatment in the prophylaxis of N-methyl-N-nitrosourea-induced mammary tumorigenesis in female Sprague-Dawley rats.
    Cancer research, 1980, Volume: 40, Issue:9

    Topics: Adrenal Glands; Animals; Depression, Chemical; Drug Synergism; Ergolines; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitrosourea Compounds; Organ Size; Ovary; Pituitary Gland; Prolactin; Rats; Time Factors; Tretinoin

1980
Effect of three retinoids on tracheal carcinogenesis with N-methyl-N-nitrosourea in hamsters.
    Journal of the National Cancer Institute, 1981, Volume: 66, Issue:5

    Topics: Amyloidosis; Animals; Carcinoma; Cricetinae; Isotretinoin; Male; Mesocricetus; Methylnitrosourea; Neoplasms, Experimental; Precancerous Conditions; Probability; Tracheal Neoplasms; Tretinoin

1981
Development and characterization of nontumorigenic and tumorigenic epithelial cell lines from rat dorsal-lateral prostate.
    Cancer research, 1994, Jul-01, Volume: 54, Issue:13

    Topics: Acid Phosphatase; Animals; Calcitriol; Cell Division; Cell Line; Dihydrotestosterone; Epithelium; Karyotyping; Male; Methylnitrosourea; Mice; Mice, Nude; Prostate; Prostatic Neoplasms; Rats; Rats, Wistar; Receptors, Androgen; Transforming Growth Factor beta; Tretinoin; Tumor Cells, Cultured

1994
Prevention of breast cancer in the rat with 9-cis-retinoic acid as a single agent and in combination with tamoxifen.
    Cancer research, 1994, Sep-01, Volume: 54, Issue:17

    Topics: Animals; Breast Neoplasms; Drug Screening Assays, Antitumor; Humans; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Tamoxifen; Tretinoin; Tumor Cells, Cultured

1994
Effect of retinoic acid (RA) in MNU-induced rat mammary tumors.
    Annals of the New York Academy of Sciences, 1995, Sep-30, Volume: 768

    Topics: Animals; Anticarcinogenic Agents; Carcinogens; Estradiol; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Ovariectomy; Rats; Rats, Sprague-Dawley; Tamoxifen; Tretinoin

1995
Midkine in the progression of rat N-nitroso-N-methylurea-induced mammary tumors.
    Molecular carcinogenesis, 1996, Volume: 17, Issue:3

    Topics: Adenocarcinoma; Animals; Carcinogens; Carrier Proteins; Cell Differentiation; Cytokines; Disease Progression; Gene Expression; Mammary Neoplasms, Experimental; Methylnitrosourea; Midkine; Rats; Rats, Inbred BUF; RNA, Messenger; Tretinoin; Tumor Cells, Cultured

1996
Differentiation of respiratory epithelium: the effects of retinoic acid and carcinogens on the expression of mucociliary vs. squamous phenotype.
    Inflammation, 1997, Volume: 21, Issue:2

    Topics: Animals; Benzo(a)pyrene; Carcinogens; Carcinoma, Squamous Cell; Cell Differentiation; Culture Media; Culture Techniques; Epithelium; Gene Expression; Lung Neoplasms; Metaplasia; Methylnitrosourea; Mucins; Phenotype; Rats; RNA, Messenger; Trachea; Tretinoin; Vitamin A Deficiency

1997
Evaluation of P19 cells for studying mechanisms of developmental toxicity: application to four direct-acting alkylating agents.
    Toxicology, 1998, May-15, Volume: 127, Issue:1-3

    Topics: Alkylating Agents; Aminobutyrates; Animals; Antineoplastic Agents, Alkylating; Carcinoma, Embryonal; Cell Differentiation; Cell Division; Dimethyl Sulfoxide; Ethyl Methanesulfonate; Ethylnitrosourea; gamma-Aminobutyric Acid; Male; Mesencephalon; Methyl Methanesulfonate; Methylnitrosourea; Mice; Neurons; Tretinoin; Tumor Cells, Cultured

1998
Effects of O6-benzylguanine on growth and differentiation of P19 embryonic carcinoma cells treated with alkylating agents.
    Teratogenesis, carcinogenesis, and mutagenesis, 1998, Volume: 18, Issue:3

    Topics: Alkylating Agents; Animals; Antineoplastic Agents; Carcinogens; Carcinoma, Embryonal; Cell Differentiation; Cell Division; Cell Survival; DNA Repair; Ethyl Methanesulfonate; Ethylnitrosourea; Guanine; Mesencephalon; Methyl Methanesulfonate; Methylnitrosourea; Mice; Neurons; O(6)-Methylguanine-DNA Methyltransferase; Rats; Tretinoin; Tumor Cells, Cultured

1998
Chemoprevention of rat prostate carcinogenesis by 9-cis-retinoic acid.
    Cancer research, 1999, Feb-01, Volume: 59, Issue:3

    Topics: Alitretinoin; Animals; Anticarcinogenic Agents; Carcinogens; Cyproterone Acetate; Dose-Response Relationship, Drug; Male; Methylnitrosourea; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Rats; Rats, Wistar; Testosterone; Tretinoin

1999
Melatonin and 9-cis-retinoic acid in the chemoprevention of NMU-induced rat mammary carcinoma.
    Advances in experimental medicine and biology, 1999, Volume: 460

    Topics: Adenocarcinoma; Alitretinoin; Animals; Anticarcinogenic Agents; Female; Mammary Neoplasms, Experimental; Melatonin; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Tretinoin

1999
Chemoprevention of NMU-induced rat mammary carcinoma with the combination of melatonin and 9-cis-retinoic acid.
    Cancer letters, 2001, Jul-26, Volume: 168, Issue:2

    Topics: Adenocarcinoma; Alitretinoin; Animals; Anticarcinogenic Agents; Antioxidants; Body Weight; Carcinogens; Drug Synergism; Drug Therapy, Combination; Estradiol; Estrogen Receptor alpha; Female; Free Radical Scavengers; Mammary Neoplasms, Experimental; Melatonin; Methylnitrosourea; Organ Size; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Tretinoin; Uterus

2001
Reduction of 1-methyl-1-nitrosourea-induced mammary gland carcinoma by in vivo application of immunostimulatory CpG motifs in Sprague-Dawley rats.
    General physiology and biophysics, 2001, Volume: 20, Issue:4

    Topics: Alkylating Agents; Amino Acid Motifs; Animals; Carcinogens; CpG Islands; Female; Mammary Neoplasms, Animal; Methylnitrosourea; Models, Statistical; Neoplasms, Experimental; Rats; Rats, Sprague-Dawley; Tretinoin

2001
Tumor prevention by 9-cis-retinoic acid in the N-nitroso-N-methylurea model of mammary carcinogenesis is potentiated by the pineal hormone melatonin.
    Breast cancer research and treatment, 2002, Volume: 72, Issue:1

    Topics: Administration, Oral; Alitretinoin; Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Female; Injections, Subcutaneous; Mammary Neoplasms, Experimental; Melatonin; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Tretinoin

2002
Analysis of altered gene expression profiles in retinoic acid or CpG-treated Sprague-Dawley rats with MNU-induced mammary adenocarcinoma by cDNA macro array.
    General physiology and biophysics, 2003, Volume: 22, Issue:1

    Topics: Adenocarcinoma; Animals; CpG Islands; DNA Mutational Analysis; Female; Gene Expression Regulation, Neoplastic; Mammary Neoplasms, Experimental; Methylnitrosourea; Oligodeoxyribonucleotides; Oligonucleotide Array Sequence Analysis; Rats; Rats, Sprague-Dawley; Spleen; Tretinoin

2003
Regression of NMU-induced mammary tumors with the combination of melatonin and 9-cis-retinoic acid.
    Cancer letters, 2005, Sep-08, Volume: 227, Issue:1

    Topics: Alitretinoin; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Estrogen Receptor alpha; Female; Mammary Neoplasms, Experimental; Melatonin; Methylnitrosourea; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tretinoin

2005
Anti-tumor effects of a novel retinoic acid metabolism blocking agent VN/14-1 in the N-methyl-N-nitrosourea-induced rat mammary carcinoma model and its effects on the uterus.
    Breast cancer research and treatment, 2012, Volume: 133, Issue:1

    Topics: Animals; Antineoplastic Agents; Apoptosis; Bone Density; Carcinoma; Cell Size; Drug Screening Assays, Antitumor; Estradiol; Female; Imidazoles; Lipid Metabolism; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Hormone-Dependent; Organ Size; Ovariectomy; Rats; Rats, Sprague-Dawley; Tretinoin; Tumor Burden; Uterus

2012
Failure of two retinoids to inhibit tracheal carcinogenesis in hamsters.
    Carcinogenesis, 1980, Volume: 1, Issue:3

    Topics: Animals; Carcinogens; Cricetinae; Isotretinoin; Male; Mesocricetus; Methylnitrosourea; Survival Rate; Tracheal Neoplasms; Treatment Failure; Tretinoin

1980