methylnitrosourea has been researched along with temozolomide in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arends, MJ; Brookes, RA; Clarke, AR; Margison, GP; Sansom, OJ; Toft, NJ; Winton, DJ; Wood, M | 1 |
| Bishop, SM; Clarke, AR; Court, H; Dudley, S; Liskay, RM; Sansom, OJ | 1 |
| Caldwell, D; Kelley, MR; Rinne, M | 1 |
| Guérard, M; Tang, L; Zeller, A | 1 |
| Chatziioannou, A; Kolisis, F; Koryllou, A; Moulos, P; Papadodima, O; Piroti, G; Pletsa, V | 1 |
| Ando, M; Inoue, Y; Iwase, Y; Kato, T; Muto, S; Uno, Y; Yamada, K | 1 |
6 other study(ies) available for methylnitrosourea and temozolomide
| Article | Year |
|---|---|
In vivo administration of O(6)-benzylguanine does not influence apoptosis or mutation frequency following DNA damage in the murine intestine, but does inhibit P450-dependent activation of dacarbazine.
Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Biotransformation; Cisplatin; Cytochrome P-450 Enzyme System; Dacarbazine; DNA Damage; Enzyme Inhibitors; Guanine; Intestine, Small; Methylnitrosourea; Mice; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Temozolomide | 2000 |
Apoptosis and mutation in the murine small intestine: loss of Mlh1- and Pms2-dependent apoptosis leads to increased mutation in vivo.
Topics: Adaptor Proteins, Signal Transducing; Adenosine Triphosphatases; Animals; Apoptosis; Base Pair Mismatch; Bromodeoxyuridine; Carrier Proteins; Dacarbazine; DNA Repair; DNA Repair Enzymes; DNA-Binding Proteins; Dose-Response Relationship, Drug; Intestine, Small; Male; Methylnitrosourea; Mice; Mice, Mutant Strains; Mismatch Repair Endonuclease PMS2; Mitotic Index; Mutation; MutL Protein Homolog 1; MutS Homolog 2 Protein; Neoplasm Proteins; Nuclear Proteins; Proto-Oncogene Proteins; Temozolomide; Time Factors | 2003 |
Transient adenoviral N-methylpurine DNA glycosylase overexpression imparts chemotherapeutic sensitivity to human breast cancer cells.
Topics: Adenoviridae; Alkylating Agents; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Comet Assay; Dacarbazine; DNA Glycosylases; DNA Repair; Dose-Response Relationship, Drug; Genetic Therapy; Genetic Vectors; Humans; Hydroxylamines; Immunohistochemistry; Methyl Methanesulfonate; Methylnitronitrosoguanidine; Methylnitrosourea; Oligonucleotides; Sensitivity and Specificity; Sulfuric Acid Esters; Temozolomide; Time Factors | 2004 |
Quantitative assessment of the dose-response of alkylating agents in DNA repair proficient and deficient ames tester strains.
Topics: Alkylating Agents; Dacarbazine; DNA Helicases; DNA Repair; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Methyl Methanesulfonate; Methylnitrosourea; Methyltransferases; Mutagenicity Tests; Mutagens; Salmonella typhimurium; Species Specificity; Temozolomide | 2014 |
Modulation of Pathways Underlying Distinct Cell Death Mechanisms in Two Human Lung Cancer Cell Lines in Response to SN1 Methylating Agents Treatment.
Topics: A549 Cells; Alkylating Agents; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Death; Cell Line, Tumor; Dacarbazine; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Ontology; Humans; Lung Neoplasms; Methylnitrosourea; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Temozolomide | 2016 |
Evaluation of the mutagenicity of alkylating agents, methylnitrosourea and temozolomide, using the rat Pig-a assay with total red blood cells or reticulocytes.
Topics: Alkylating Agents; Animals; Body Weight; Dacarbazine; Erythrocytes; Male; Membrane Proteins; Methylnitrosourea; Mutagenicity Tests; Mutagens; Rats; Rats, Sprague-Dawley; Reticulocytes; Temozolomide | 2016 |