Page last updated: 2024-08-21

methylnitrosourea and saccharin

methylnitrosourea has been researched along with saccharin in 21 studies

Research

Studies (21)

Timeframe	Studies, this research(%)	All Research%
pre-1990	18 (85.71)	18.7374
1990's	3 (14.29)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Reuber, MD	1
Green, U; Rippel, W	1
Chowaniec, J; Hicks, RM	1
Cohen, SM; Garland, EM; Macatee, TL; Mann, AM; Masui, T; Okamura, T; Smith, RA	1
Hicks, RM; Jani, H; Knowles, MA	1
Jani, H; Knowles, MA	1
Hodges, GM; Howlett, AR; Norman, JT; Spacey, GD	1
Jani, H; Nicholson, LJ	1
Kadlubar, FF; Kumari, L; Lehman, TA; Milo, GE; Noyes, I; Oldham, JW; West, RW	1
Schoenig, GP	1
Delongchamp, RR; Gaylor, DW; Haskin, MG; Kadlubar, FF; Sheldon, WG; West, RW	1
Althoff, J; Green, U; Schneider, P; Soudah, B	1
Miller, CT	1
Fukushima, S; Imaida, K; Ito, N; Kurata, Y; Tsuda, H	1
El-Gerzawi, S; Heatfield, BM; Trump, BF	1
Bonneville, MA; Caruthers, JM	1
Hicks, RM	1
Althoff, J; Brune, H; Deutsch-Wenzel, R; Green, U; Schneider, P	1
Chowaniec, J; Grasso, P; Hicks, RM; Hooson, J	1
Allen, RR; Gaylor, DW; Kadlubar, FF; Sheldon, WG; West, RW	1
Gendel, SM; Ogretmen, B; Ratajczak, H; Stark, BC	1

Reviews

3 review(s) available for methylnitrosourea and saccharin

Article	Year
Carcinogenicity of saccharin. Environmental health perspectives, 1978, Volume: 25 Topics: Animals; Carcinogens; Diet; Female; Lung Neoplasms; Male; Methylnitrosourea; Mice; Parasitic Diseases; Rats; Saccharin; Sex Factors; Species Specificity; Tosyl Compounds; United States; United States Food and Drug Administration; Urinary Bladder Calculi; Urinary Bladder Neoplasms; Urogenital Neoplasms	1978
Luminal plasma membrane alterations in bladder cancer. Investigative urology, 1980, Volume: 17, Issue:5 Topics: Animals; Cell Membrane; Cell Membrane Permeability; Cilia; FANFT; Intercellular Junctions; Methylnitrosourea; Microvilli; Neoplasms, Experimental; Rats; Saccharin; Urinary Bladder; Urinary Bladder Neoplasms	1980
Multistage carcinogenesis in the urinary bladder. British medical bulletin, 1980, Volume: 36, Issue:1 Topics: Animals; Cricetinae; Cyclamates; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Synergism; Female; Formamides; Methylnitrosourea; Neoplasms, Experimental; Rats; Saccharin; Skin Neoplasms; Urinary Bladder Calculi; Urinary Bladder Neoplasms	1980

Other Studies

18 other study(ies) available for methylnitrosourea and saccharin

Article	Year
Bladder calculi in rats treated with nitrosomethylurea and fed artificial sweeteners. Experimentelle Pathologie, 1979, Volume: 17, Issue:9 Topics: Animals; Calcium Carbonate; Cyclamates; Female; Methylnitrosourea; Radiography; Rats; Saccharin; Urinary Bladder Calculi	1979
The importance of synergy between weak carcinogens in the induction of bladder cancer in experimental animals and humans. Cancer research, 1977, Volume: 37, Issue:8 Pt 2 Topics: 2-Naphthylamine; Animals; Carcinogens; Carcinogens, Environmental; Carcinoma, Transitional Cell; Cyclamates; Drug Synergism; Female; Humans; Male; Methylnitrosourea; Neoplasms, Experimental; Rats; Saccharin; Urinary Bladder Neoplasms	1977
Direct DNA sequencing of the rat neu oncogene transmembrane domain reveals no mutation in urinary bladder carcinomas induced by N-butyl-N-(4-hydroxybutyl)nitrosamine, N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide or N-methyl-N-nitrosourea. Carcinogenesis, 1991, Volume: 12, Issue:10 Topics: Amino Acid Sequence; Animals; Base Sequence; Butylhydroxybutylnitrosamine; DNA, Neoplasm; FANFT; Male; Membranes; Methylnitrosourea; Molecular Sequence Data; Mutation; Oncogenes; Polymerase Chain Reaction; Proto-Oncogene Proteins; Rats; Rats, Inbred F344; Receptor, ErbB-2; Saccharin; Uracil; Urinary Bladder Neoplasms	1991
Induction of morphological changes in the urothelium of cultured adult rat bladder by sodium saccharin and sodium cyclamate. Carcinogenesis, 1986, Volume: 7, Issue:5 Topics: Animals; Cyclamates; Epithelium; Female; Hyperplasia; Methylnitrosourea; Microscopy, Electron, Scanning; Organ Culture Techniques; Rats; Rats, Inbred F344; Saccharin; Time Factors; Urinary Bladder; Urinary Bladder Neoplasms	1986
Multistage transformation of cultured rat urothelium: the effects of N-methyl-N-nitrosourea, sodium saccharin, sodium cyclamate and 12-O-tetradecanoylphorbol-13-acetate. Carcinogenesis, 1986, Volume: 7, Issue:12 Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Cyclamates; Epithelium; Female; Hyperplasia; Methylnitrosourea; Phenotype; Rats; Rats, Inbred F344; Saccharin; Tetradecanoylphorbol Acetate; Urinary Bladder	1986
Effects of treatment with N-methyl-N-nitrosourea, artificial sweeteners, and cyclophosphamide on adult rat urinary bladder in vitro. Laboratory investigation; a journal of technical methods and pathology, 1987, Volume: 57, Issue:4 Topics: Animals; Cyclamates; Cyclophosphamide; Epithelium; Female; Hyperplasia; Methylnitrosourea; Microscopy, Electron; Microscopy, Electron, Scanning; Organ Culture Techniques; Precancerous Conditions; Rats; Rats, Inbred Strains; Saccharin; Sweetening Agents; Urinary Bladder; Urinary Bladder Neoplasms	1987
Effects of sodium cyclamate and sodium saccharin on focus induction in explant cultures of rat bladder. International journal of cancer, 1988, Aug-15, Volume: 42, Issue:2 Topics: Animals; Cells, Cultured; Cyclamates; Female; Methylnitrosourea; Rats; Rats, Inbred F344; Saccharin; Urinary Bladder	1988
Cocarcinogenicity of saccharin and N-alkylnitrosoureas in cultured human diploid fibroblasts. Journal of toxicology and environmental health, 1988, Volume: 24, Issue:3 Topics: Antigens, Neoplasm; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Ethylnitrosourea; Fibroblasts; Humans; Insulin; Interphase; Methylnitrosourea; Saccharin	1988
The effects of saccharin on the development of neoplastic lesions initiated with n-methyl-n-nitrosourea. Fundamental and applied toxicology : official journal of the Society of Toxicology, 1988, Volume: 10, Issue:4 Topics: Animals; Drug Interactions; Methylnitrosourea; Mice; Neoplasms, Experimental; Saccharin	1988
The effects of saccharin on the development of neoplastic lesions initiated with N-methyl-N-nitrosourea in the rat urothelium. Fundamental and applied toxicology : official journal of the Society of Toxicology, 1986, Volume: 7, Issue:4 Topics: Animals; Carcinogens; Dose-Response Relationship, Drug; Epithelium; Female; Methylnitrosourea; Rats; Rats, Inbred Strains; Risk; Saccharin; Urinary Bladder Neoplasms	1986
Neoplastic lesions in the urinary tract of Wistar rats after treatment with N-methyl-N-nitrosourea (MNU) and artificial sweeteners. Experimental pathology, 1981, Volume: 20, Issue:4 Topics: Animals; Calcium Carbonate; Cyclamates; Drug Synergism; Female; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Rats, Inbred Strains; Saccharin; Sweetening Agents; Urinary Tract; Urologic Neoplasms	1981
Effects of saccharin and urine on the decomposition of N-nitrosomethylurea. IARC scientific publications, 1984, Issue:57 Topics: Animals; Chemical Phenomena; Chemistry; In Vitro Techniques; Methylnitrosourea; Mutagenicity Tests; Nitrosourea Compounds; Rats; Saccharin; Salmonella typhimurium; Spectrophotometry, Ultraviolet; Urine	1984
Organ-specific promoting effect of phenobarbital and saccharin in induction of thyroid, liver, and urinary bladder tumors in rats after initiation with N-nitrosomethylurea. Cancer research, 1983, Volume: 43, Issue:7 Topics: Adenocarcinoma, Papillary; Animals; Cocarcinogenesis; Liver Neoplasms; Male; Methylnitrosourea; Nitrosourea Compounds; Organ Specificity; Papilloma; Phenobarbital; Precancerous Conditions; Rats; Rats, Inbred F344; Saccharin; Thyroid Neoplasms; Urinary Bladder Neoplasms	1983
N-Methyl-N-nitrosourea and saccharin: effects on epithelium of normal human urinary bladder in vitro. Journal of the National Cancer Institute, 1982, Volume: 69, Issue:3 Topics: Cocarcinogenesis; Culture Techniques; Epithelium; Humans; Hyperplasia; Methylnitrosourea; Nitrosourea Compounds; Precancerous Conditions; Saccharin; Urinary Bladder	1982
Syncarcinogenic action of saccharin or sodium cyclamate in the induction of bladder tumours in MNU-pretreated rats. Food and cosmetics toxicology, 1980, Volume: 18, Issue:6 Topics: Animals; Body Weight; Carcinogens; Cyclamates; Drug Synergism; Eating; Female; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Saccharin; Urinary Bladder Neoplasms; Urologic Neoplasms	1980
Ortho-toluene sulphonamide and saccharin in the promotion of bladder cancer in the rat. British journal of cancer, 1980, Volume: 42, Issue:1 Topics: Animals; Body Weight; Drinking; Eating; Female; Kidney; Methylnitrosourea; Neoplasms, Experimental; Organ Size; Rats; Saccharin; Sulfonamides; Toluene; Tosyl Compounds; Urinary Bladder; Urinary Bladder Neoplasms	1980
Study of sodium saccharin co-carcinogenicity in the rat. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1994, Volume: 32, Issue:3 Topics: Animals; Carcinogenicity Tests; Carcinoma, Transitional Cell; Cocarcinogenesis; Dose-Response Relationship, Drug; Female; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Saccharin; Urinary Bladder; Urinary Bladder Neoplasms	1994
Effects of sodium saccharin and linoleic acid on mRNA levels of Her2/neu and p53 in a human breast epithelial cell line. Cancer letters, 1996, Apr-19, Volume: 102, Issue:1-2 Topics: 9,10-Dimethyl-1,2-benzanthracene; Breast; Carcinogens; Cell Line; Dose-Response Relationship, Drug; Epithelium; Gene Expression; Genes, erbB-2; Genes, p53; Humans; Linoleic Acid; Linoleic Acids; Methylnitrosourea; Receptor, ErbB-2; RNA, Messenger; Saccharin; Sweetening Agents; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53	1996