Page last updated: 2024-08-21

methylnitrosourea and o(6)-benzylguanine

methylnitrosourea has been researched along with o(6)-benzylguanine in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (71.43)18.2507
2000's2 (28.57)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Faustman, EM; Kidney, JK1
Anver, MR; Lijinsky, W; Moschel, RC; Pegg, AE1
Armstrong, MJ; Galloway, SM1
Faustman, EM; Seeley, MR1
Aquilina, G; Bignami, M; Branch, P; Fiumicino, S; Humbert, O; Karran, P; Oda, S; Zijno, A1
Arends, MJ; Brookes, RA; Clarke, AR; Margison, GP; Sansom, OJ; Toft, NJ; Winton, DJ; Wood, M1
Boley, SE; Maher, VM; McCormick, JJ; McManus, TP1

Other Studies

7 other study(ies) available for methylnitrosourea and o(6)-benzylguanine

ArticleYear
Modulation of nitrosourea toxicity in rodent embryonic cells by O6-benzylguanine, a depletor of O6-methylguanine-DNA methyltransferase.
    Toxicology and applied pharmacology, 1995, Volume: 133, Issue:1

    Topics: Animals; Cell Differentiation; Cells, Cultured; DNA Adducts; Ethylnitrosourea; Female; Guanine; Mesencephalon; Methylnitrosourea; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Pregnancy; Rats; Rats, Sprague-Dawley

1995
Effects of inhibition of O6-alkylguanine-DNA alkyltransferase in rats on carcinogenesis by methylnitrosourea and ethylnitrosourea.
    Japanese journal of cancer research : Gann, 1994, Volume: 85, Issue:3

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents; Ethylnitrosourea; Female; Guanine; Liver; Methylnitrosourea; Methyltransferases; Neoplasms, Experimental; O(6)-Methylguanine-DNA Methyltransferase; Rats; Rats, Inbred F344

1994
Mismatch repair provokes chromosome aberrations in hamster cells treated with methylating agents or 6-thioguanine, but not with ethylating agents.
    Mutation research, 1997, Feb-03, Volume: 373, Issue:2

    Topics: Alkylating Agents; Animals; Cell Division; CHO Cells; Chromosome Aberrations; Cricetinae; DNA Repair; Enzyme Inhibitors; Guanine; Methylnitronitrosoguanidine; Methylnitrosourea; Thioguanine

1997
Effects of O6-benzylguanine on growth and differentiation of P19 embryonic carcinoma cells treated with alkylating agents.
    Teratogenesis, carcinogenesis, and mutagenesis, 1998, Volume: 18, Issue:3

    Topics: Alkylating Agents; Animals; Antineoplastic Agents; Carcinogens; Carcinoma, Embryonal; Cell Differentiation; Cell Division; Cell Survival; DNA Repair; Ethyl Methanesulfonate; Ethylnitrosourea; Guanine; Mesencephalon; Methyl Methanesulfonate; Methylnitrosourea; Mice; Neurons; O(6)-Methylguanine-DNA Methyltransferase; Rats; Tretinoin; Tumor Cells, Cultured

1998
Mismatch repair and differential sensitivity of mouse and human cells to methylating agents.
    Carcinogenesis, 1999, Volume: 20, Issue:2

    Topics: 3T3 Cells; Alkylating Agents; Animals; Antineoplastic Agents; Apoptosis; Base Pair Mismatch; Chromosomes, Human, Pair 2; DNA Methylation; DNA Repair; DNA-Binding Proteins; Drug Resistance, Neoplasm; Gene Transfer Techniques; Genotype; Guanine; HeLa Cells; Humans; Melanoma, Experimental; Methylnitronitrosoguanidine; Methylnitrosourea; Mice; MutS Homolog 2 Protein; Proto-Oncogene Proteins; Species Specificity; Tumor Cells, Cultured

1999
In vivo administration of O(6)-benzylguanine does not influence apoptosis or mutation frequency following DNA damage in the murine intestine, but does inhibit P450-dependent activation of dacarbazine.
    Carcinogenesis, 2000, Volume: 21, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Biotransformation; Cisplatin; Cytochrome P-450 Enzyme System; Dacarbazine; DNA Damage; Enzyme Inhibitors; Guanine; Intestine, Small; Methylnitrosourea; Mice; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Temozolomide

2000
Malignant transformation of human fibroblast cell strain MSU-1.1 by N-methyl-N-nitrosourea: evidence of elimination of p53 by homologous recombination.
    Cancer research, 2000, Aug-01, Volume: 60, Issue:15

    Topics: Alleles; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Codon; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibroblasts; Gene Deletion; Genes, p53; Guanine; Homozygote; Humans; Loss of Heterozygosity; Methylnitrosourea; O(6)-Methylguanine-DNA Methyltransferase; Recombination, Genetic; Transcriptional Activation

2000