methylnitrosourea has been researched along with lomustine in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (83.87) | 18.7374 |
| 1990's | 2 (6.45) | 18.2507 |
| 2000's | 3 (9.68) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Adamson, DJ; Brockman, RW; Elliott, RD; Montgomery, JA; Riordan, JM; Shaddix, SC; Thomas, HJ | 1 |
| Brockman, RW; Montgomery, JA; Thomas, HJ; Wheeler, GP | 1 |
| Bradley, MO; Erickson, LC; Kohn, KW | 1 |
| Baxter, D; Cunningham, TJ; Horton, J; Nelson, L; Olson, KB; Rosenbaum, C; Sponzo, RW; Taylor, SG | 1 |
| Assekritova, IV; Batinov, IN; Bychkov, MB; Perevodchikova, NI; Vaarik, KhM | 1 |
| Schein, PS; Smulson, ME; Sudhakar, S; Tew, KD; Woolley, PV | 1 |
| Auletta, AE; Martz, AG; Parmar, AS | 1 |
| Ewig, RA; Kohn, KW | 1 |
| Assekritova, IV; Brazhnikova, EI; Moroz, LV; Vaarik, KhM; Voznyĭ, EK | 1 |
| Engelmann, U; Kuschnir, H; Schmack, B; Schmidt, H; Waldbaur, H | 1 |
| Lokich, JJ; Skarin, AT | 1 |
| Schabel, FM | 1 |
| Kohn, KW | 1 |
| Carter, SK; Slavik, M; Wasserman, TH | 1 |
| Epstein, EH; Zackheim, HS | 1 |
| Said, B; Shank, RC | 1 |
| Arkhipov, AI; Gershanovich, ML; Vilensky, BS | 1 |
| Clyde, C; Dolan, ME; Erickson, LC; Hora, NK; Norbeck, L; Pegg, AE | 1 |
| Bychkov, MB | 1 |
| Arkhipov, AI; Gershanovich, ML; Vilenskiĭ, BS | 1 |
| Kogonia, LM; Moros, LW; Perevodchikova, NJ | 1 |
| Hellwig, D; Mennel, HD; Simon, H | 1 |
| Schein, PS; Tew, KD; Wang, AL | 1 |
| Bychkov, MB; Perevodchikova, NI | 1 |
| Danil'ian, VM; Linchenko, IF | 1 |
| Epstein, JH | 1 |
| Deen, DF; Marton, LJ; Oredsson, SM | 1 |
| Sokolova, II; Trakhtenberg, AKh; Trubnikova, EN | 1 |
| Aquilina, G; Bignami, M; Branch, P; Ceccotti, S; Crescenzi, M; Karran, P; Martinelli, S; Soddu, S | 1 |
| Weller, M; Winter, S | 1 |
| Filatova, LV; Gershanovich, ML | 1 |
5 review(s) available for methylnitrosourea and lomustine
| Article | Year |
|---|---|
Nitrosoureas: a review of experimental antitumor activity.
Topics: Animals; Carmustine; Colonic Neoplasms; Drug Evaluation, Preclinical; Drug Resistance; Drug Therapy, Combination; Leukemia L1210; Lomustine; Lung Neoplasms; Mammary Neoplasms, Experimental; Melanoma; Methylnitronitrosoguanidine; Methylnitrosourea; Mice; Neoplasms, Experimental; Nitrosourea Compounds; Semustine | 1976 |
Clinical comparison of the nitrosoureas.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Breast Neoplasms; Carmustine; Chemical Phenomena; Chemistry; Colonic Neoplasms; Drug Therapy, Combination; Hodgkin Disease; Humans; Lomustine; Lung Neoplasms; Lymphoma; Melanoma; Methylnitrosourea; Mice; Neoplasms, Experimental; Nitrosourea Compounds; Rectal Neoplasms | 1975 |
Nitrosourea derivatives for the treatment of Hodgkin's disease involving the central nervous system: a study of 23 cases.
Topics: Adolescent; Adult; Brain Diseases; Female; Hodgkin Disease; Humans; Lomustine; Male; Methylnitrosourea; Middle Aged; Neoplasm Staging; Spinal Cord Compression; Survival Analysis | 1990 |
[Polychemotherapy and radiotherapy for small cell cancer of the lung].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Humans; Lomustine; Lung Neoplasms; Methotrexate; Methylnitrosourea; Prednisone; Procarbazine; Vincristine | 1983 |
Photocarcinogenesis, skin cancer, and aging.
Topics: Aging; Animals; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; DNA; Humans; Lomustine; Melanoma; Methylnitrosourea; Mice; Neoplasms, Radiation-Induced; Radiation-Sensitizing Agents; Rats; Skin Neoplasms; Sunlight; Ultraviolet Rays | 1983 |
2 trial(s) available for methylnitrosourea and lomustine
| Article | Year |
|---|---|
Nitrosourea combination chemotherapy: 1-(2-chloroethyl)-3-(4-methyl cyclohexyl)-1-nitrosourea (methyl-CCNU) and cyclophosphamide.
Topics: Adult; Aged; Breast Neoplasms; Clinical Trials as Topic; Cyclophosphamide; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Lomustine; Lung Neoplasms; Male; Methylnitrosourea; Middle Aged; Neoplasms; Nitrosourea Compounds; Stomach Neoplasms | 1975 |
[Combination chemotherapy of disseminated skin melanoma with nitrosomethylurea].
Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Dacarbazine; Dactinomycin; Drug Administration Schedule; Humans; Lomustine; Melanoma; Methylnitrosourea; Prognosis; Skin Neoplasms; Vincristine | 1986 |
24 other study(ies) available for methylnitrosourea and lomustine
| Article | Year |
|---|---|
Nitrosoureido nucleosides as potential inhibitors of nucleotide biosynthesis.
Topics: Animals; Carmustine; Cell Division; DNA Replication; Drug Stability; Indicators and Reagents; Leukemia L1210; Lomustine; Mice; Neoplasm Proteins; Nitrosourea Compounds; Nucleosides; Nucleotides; Structure-Activity Relationship; Transcription, Genetic | 1988 |
Potential inhibitors of nucleotide biosynthesis. 1. Nitrosoureidonucleosides. 2.
Topics: Animals; Binding Sites; Chemical Phenomena; Chemistry; Drug Stability; Enzyme Inhibitors; Leukemia P388; Nitrosourea Compounds; Nucleosides | 1981 |
Measurements of DNA damage in Chinese hamster cells treated with equitoxic and equimutagenic doses of nitrosoureas.
Topics: Carmustine; Cell Line; Cell Survival; Cyanates; DNA; Dose-Response Relationship, Drug; Ethyl Chloride; Lomustine; Methylnitrosourea; Mutation; Nitrosourea Compounds; Streptozocin; Time Factors | 1978 |
Treatment of grade III and IV astrocytoma with dimethyl triazeno imidazole carboxamide (DTIC, NSC-45388) alone and in combination with CCNU (NSC-79037) or methyl CCNU (MeCCNU, NSC-95441).
Topics: Adult; Brain Neoplasms; Dacarbazine; Drug Evaluation; Drug Therapy, Combination; Female; Glioblastoma; Humans; Leukopenia; Lomustine; Male; Methylnitrosourea; Middle Aged; Thrombocytopenia; Triazenes | 1975 |
[Comparative study of the effectiveness of N-nitrosomethylurea and 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea combined with cyclophosphane in inoperable lung cancer].
Topics: Adenocarcinoma; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Therapy, Combination; Humans; Lomustine; Lung Neoplasms; Methylnitrosourea; Nitrosourea Compounds | 1978 |
Nitrosourea interaction with chromatin and effect on poly(adenosine diphosphate ribose) polymerase activity.
Topics: Alkylation; Chromatin; DNA; Enzyme Activation; HeLa Cells; Histones; Humans; Lomustine; Methylnitrosourea; NAD+ Nucleosidase; Nitrosourea Compounds; Poly(ADP-ribose) Polymerases | 1979 |
Mutagenicity of nitrosourea compounds for Salmonella typhimurium.
Topics: Carmustine; Lomustine; Methods; Methylnitrosourea; Mutagens; Nitrosourea Compounds; Salmonella typhimurium; Semustine | 1978 |
DNA damage and repair in mouse leukemia L1210 cells treated with nitrogen mustard, 1,3-bis(2-chloroethyl)-1-nitrosourea, and other nitrosoureas.
Topics: Animals; Carmustine; Cell Survival; Cells, Cultured; Chemical Phenomena; Chemistry; DNA Repair; DNA, Neoplasm; DNA, Single-Stranded; Leukemia L1210; Lomustine; Mechlorethamine; Methylnitrosourea; Neoplasm Proteins; Nitrosourea Compounds | 1977 |
[Combined chemotherapy of disaeminated melanoma].
Topics: Adult; Aged; Aminoimidazole Carboxamide; Antineoplastic Agents; Dactinomycin; Drug Therapy, Combination; Female; Humans; Lomustine; Male; Melanoma; Methylnitrosourea; Middle Aged; Skin Neoplasms; Vincristine | 1978 |
Experiments on the chemotheraphy of a transplantable glioblastoma in the rat, employing 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU).
Topics: Animals; Brain Neoplasms; Glioma; Lomustine; Male; Methylnitrosourea; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosourea Compounds; Rats | 1978 |
Interstrand cross-linking of DNA by 1,3-bis(2-chloroethyl)-1-nitrosourea and other 1-(2-haloethyl)-1-nitrosoureas.
Topics: Carmustine; Chemical Phenomena; Chemistry; DNA; Kinetics; Lomustine; Methylnitrosourea; Nitrosourea Compounds | 1977 |
Treatment of mycosis fungoides with topical nitrosourea compounds: Further studies.
Topics: Administration, Topical; Adult; Aged; Bone Marrow; Carmustine; Cross Reactions; Drug Hypersensitivity; Female; Humans; Lomustine; Male; Mechlorethamine; Methylnitrosourea; Middle Aged; Mycosis Fungoides; Nitrosourea Compounds; Skin Neoplasms | 1975 |
Nearest neighbor effects on carcinogen binding to guanine runs in DNA.
Topics: Aflatoxin B1; Aflatoxins; Autoradiography; Base Sequence; Benzo(a)pyrene; Binding, Competitive; Carcinogens; DNA; Electrophoresis, Agar Gel; Guanine; Hydrogen-Ion Concentration; Hydrolysis; Lomustine; Methylnitrosourea; Molecular Sequence Data; Photochemistry; Plasmids | 1991 |
Expression of mammalian O6-alkylguanine-DNA alkyltransferase in a cell line sensitive to alkylating agents.
Topics: Alkylating Agents; Animals; Carmustine; Cell Division; Cell Line; Cricetinae; Cricetulus; Female; Guanine; Kinetics; Lomustine; Methylnitronitrosoguanidine; Methylnitrosourea; Methyltransferases; Mitoguazone; O(6)-Methylguanine-DNA Methyltransferase; Ovary; Transfection | 1989 |
[Chemotherapy and combined chemo- and radiotherapy of small cell lung cancer].
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Dacarbazine; Doxorubicin; Humans; Lomustine; Lung Neoplasms; Methotrexate; Methylnitrosourea; Procarbazine; Prospidium; Vincristine | 1985 |
[Use of nitrosourea derivatives in the treatment of patients with Hodgkin's disease with lesions of the central nervous system].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Drug Evaluation; Hodgkin Disease; Humans; Lomustine; Methylnitrosourea; Middle Aged; Prednisolone; Procarbazine; Spinal Cord Neoplasms; Vinca Alkaloids | 1988 |
Chemotherapy in intracerebrally transplanted tumors induced with transplacental administration of ethylnitrosourea in rats.
Topics: Animals; Brain Neoplasms; Drug Administration Schedule; Ethylnitrosourea; Female; Lomustine; Methylnitrosourea; Neoplasm Transplantation; Placenta; Pregnancy; Rats; Spinal Cord Neoplasms | 1986 |
Alkylating agent interactions with the nuclear matrix.
Topics: Alkylating Agents; Cell Nucleus; Chlorambucil; DNA; HeLa Cells; Humans; Lomustine; Methylnitrosourea; Protein Binding; Ribonucleoproteins; Streptozocin | 1983 |
Modern problems of clinical chemotherapy of malignant tumours.
Topics: Antineoplastic Agents; Carcinoma, Small Cell; Carubicin; Dacarbazine; Dactinomycin; Drug Therapy, Combination; Female; Humans; Lomustine; Lung Neoplasms; Male; Melanoma; Methylnitrosourea; Neoplasms; Sarcoma; Skin Neoplasms; Soft Tissue Neoplasms; Vincristine | 1980 |
Influence of polyamine depletion caused by alpha-difluoromethylornithine, an enzyme-activated irreversible inhibitor of ornithine decarboxylase, on alkylation- and carbamoylation-induced cytotoxicity in 9L rat brain tumor cells in vitro.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Carboxy-Lyases; Carmustine; Cell Line; Cell Survival; Drug Synergism; Eflornithine; Ethylnitrosourea; Lomustine; Methylnitrosourea; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Rats | 1983 |
[Hematopoiesis during combined treatment of lung cancer patients with cyclophosphan and nitrosomethylurea or CCNU].
Topics: Adult; Aged; Anemia, Aplastic; Cyclophosphamide; Female; Humans; Lomustine; Lung Neoplasms; Male; Methylnitrosourea; Middle Aged; Nitrosourea Compounds | 1980 |
Mismatch repair and p53 independently affect sensitivity to N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosourea.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Substitution; Apoptosis; Base Pair Mismatch; bcl-2-Associated X Protein; Carrier Proteins; Cell Cycle; Cell Survival; Codon; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Female; Genes, p53; Humans; In Situ Nick-End Labeling; Lomustine; Methylnitrosourea; MutL Protein Homolog 1; Neoplasm Proteins; Nuclear Proteins; Ovarian Neoplasms; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Recombinant Proteins; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2000 |
Poly(ADP-ribose) polymerase-independent potentiation of nitrosourea cytotoxicity by 3-aminobenzamide in human malignant glioma cells.
Topics: Benzamides; Binding Sites; Carmustine; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; G2 Phase; Glioma; Humans; Lomustine; Methylnitrosourea; Mitosis; Nimustine; Nitrosourea Compounds; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Tumor Cells, Cultured | 2000 |
[Clinical features and combined treatment of the central nervous system in Hodgkin's disease].
Topics: Adolescent; Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Chemotherapy, Adjuvant; Child; Female; Hodgkin Disease; Humans; Lomustine; Male; Methylnitrosourea; Middle Aged; Prognosis; Radiotherapy, Adjuvant; Retrospective Studies; Risk Factors; Spinal Cord Compression; Survival Analysis; Treatment Outcome; Young Adult | 2008 |