Page last updated: 2024-08-21

methylnitrosourea and fluorouracil

methylnitrosourea has been researched along with fluorouracil in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19907 (35.00)18.7374
1990's4 (20.00)18.2507
2000's3 (15.00)29.6817
2010's5 (25.00)24.3611
2020's1 (5.00)2.80

Authors

AuthorsStudies
Enck, RE1
Kono, K; Narisawa, T; Takahashi, T; Yamaguchi, T1
Moroz, IA; Pelevina, II; Sergeeva, NS; Skotinkova, OI; Sviridova, IK1
Berger, MR; Habs, M; Schmähl, D1
Fiebig, HH; Schmähl, D1
Narisawa, T; Sato, M; Takahashi, T; Tani, M1
Berger, M; Habs, M; Schmähl, D1
Kohno, KI; Narisawa, T; Takahashi, T; Yamaguchi, T1
Kasamatsu, T; Kawazoe, Y; Kohda, K1
Griffiths, JR; Lemaire, LP; McSheehy, PM1
Griffiths, JR; Howe, FA; Lemaire, L; Rodrigues, LM1
Estensen, RD; Wattenberg, LW; Wiedmann, TS1
Glaab, WE; Skopek, TR; Vlasakova, K1
Hirabayashi, Y; Huo, Y; Inoue, T; Kanno, J; Kodama, Y; Ott, T; Trosko, JE; Tsuboi, I; Yoon, BI1
Brown, RJ; Gabrielson, E; Huso, DL; Jacobs, LK; Jeter, S; Khouri, NF; Kominsky, SL; Lange, JR; Mori, T; Powers, P; Rudek, MA; Stearns, V; Sukumar, S; Tarpinian, K; Tsangaris, TN; Yoshida, T; Zhang, Z1
Bondarenko, NA; Kabakov, AV; Kazakov, OV; Konenkov, VI; Lykov, AP; Poveshchenko, AF; Poveshchenko, OV; Raiter, TV; Strunkin, DN1
Ishchenko, IY; Kabakov, AV; Kazakov, OV; Konenkov, VI; Michurina, SV; Poveshchenko, AF; Raiter, TV; Strunkin, DN1
Ishchenko, IY; Kabakov, AV; Kazakov, OV; Konenkov, VI; Lykov, AP; Michurina, SV; Poveshchenko, AF; Raiter, TV; Strunkin, DN1
Kabakov, AV; Kazakov, OV; Konenkov, VI; Lykov, AP; Poveshchenko, AF; Poveshchenko, OV; Raiter, TV; Strunkin, DN1
Bogachev, SS; Kabakov, AV; Kazakov, OV; Konenkov, VI; Lykov, AP; Poveshchenko, AF; Raiter, TV; Strunkin, DN1

Reviews

1 review(s) available for methylnitrosourea and fluorouracil

ArticleYear
Endocrine and cytostatic treatment of experimental mammary cancer.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1980, Volume: 71

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carmustine; Castration; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Ergolines; Female; Fluorouracil; Mammary Neoplasms, Experimental; Methotrexate; Methylnitrosourea; Mice; Nitrosourea Compounds; Prednisolone; Rats; Tamoxifen; Vincristine

1980

Trials

1 trial(s) available for methylnitrosourea and fluorouracil

ArticleYear
Preclinical and clinical evaluation of intraductally administered agents in early breast cancer.
    Science translational medicine, 2011, Oct-26, Volume: 3, Issue:106

    Topics: Adult; Animals; Antineoplastic Agents; Breast Neoplasms; Carboplatin; Doxorubicin; Drug Administration Routes; Female; Fluorouracil; Humans; Mammary Glands, Animal; Mammary Neoplasms, Animal; Methylnitrosourea; Paclitaxel; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Young Adult

2011

Other Studies

18 other study(ies) available for methylnitrosourea and fluorouracil

ArticleYear
Mallory-Weiss lesion following cancer chemotherapy.
    Lancet (London, England), 1977, Oct-29, Volume: 2, Issue:8044

    Topics: Drug Therapy, Combination; Fluorouracil; Humans; Lung Neoplasms; Male; Mallory-Weiss Syndrome; Methylnitrosourea; Middle Aged; Neoplasm Metastasis; Nitrosourea Compounds; Semustine; Vomiting

1977
Cancer chemotherapy model using autochthonous large bowel cancer in rats.
    Gan, 1978, Volume: 69, Issue:3

    Topics: Administration, Topical; Animals; Drug Evaluation, Preclinical; Female; Fluorouracil; Intestinal Neoplasms; Methylnitrosourea; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Semustine

1978
[Assessment of individual sensitivity to chemotherapy of human pulmonary tumors transplanted to subrenal capsule of CBA mice].
    Eksperimental'naia onkologiia, 1990, Volume: 12, Issue:4

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Fluorouracil; Humans; Lung Neoplasms; Male; Methotrexate; Methylnitrosourea; Mice; Mice, Inbred CBA; Prospidium; Subrenal Capsule Assay; Vincristine

1990
[Experimental toxicologic and therapeutic studies on the activity of the CMF(cyclophosphamide-methotrexate-5-fluorouracil) scheme versus the VMF(vincristine-methotrexate-5-fluorouracil) scheme].
    Archiv fur Geschwulstforschung, 1984, Volume: 54, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma 256, Walker; Cyclophosphamide; Female; Fluorouracil; Male; Mammary Neoplasms, Experimental; Methotrexate; Methylnitrosourea; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Sarcoma, Yoshida; Vincristine

1984
Chemoprevention of development of colonic adenomatosis and carcinomatosis with 5-fluorouracil and ftorafur on animal model.
    Journal of cancer research and clinical oncology, 1980, Volume: 97, Issue:3

    Topics: Adenoma; Animals; Carcinoma; Colon; Colonic Neoplasms; Female; Fluorouracil; Methylnitrosourea; Neoplasms, Experimental; Rats; Tegafur

1980
Noncarcinogenic chemotherapy with a combination of vincristine, methotrexate and 5-fluorouracil (VMF) in rats.
    International journal of cancer, 1983, Aug-15, Volume: 32, Issue:2

    Topics: Animals; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Therapy, Combination; Female; Fluorouracil; Male; Mammary Neoplasms, Experimental; Methotrexate; Methylnitrosourea; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Time Factors; Vincristine

1983
Chemoprevention of development of colonic adenomatosis and carcinomatosis with intrarectal dose of 5-FU on animal model.
    Cancer, 1980, Volume: 45, Issue:3

    Topics: Adenoma; Animals; Colonic Neoplasms; Female; Fluorouracil; Injections, Intraperitoneal; Methylnitrosourea; Neoplasms, Experimental; Rats; Rats, Inbred F344; Rectum

1980
Comparison of chemically induced DNA breakage in cellular and subcellular systems using the comet assay.
    Mutation research, 1996, Jul-10, Volume: 369, Issue:1-2

    Topics: 4-Nitroquinoline-1-oxide; Animals; Antimetabolites, Antineoplastic; Bleomycin; DNA; DNA Damage; Fluorouracil; Hydrogen Peroxide; Leukemia L1210; Methotrexate; Methylnitrosourea; Mice; Mutagenicity Tests; Mutagens; Subcellular Fractions; Tumor Cells, Cultured

1996
Pre-treatment energy status of primary rat tumours as the best predictor of response to 5-fluorouracil chemotherapy: a magnetic resonance spectroscopy study in vivo.
    Cancer chemotherapy and pharmacology, 1998, Volume: 42, Issue:3

    Topics: Analysis of Variance; Animals; Antimetabolites, Antineoplastic; Carcinogens; Energy Metabolism; Female; Fluorouracil; Magnetic Resonance Spectroscopy; Methylnitrosourea; Neoplasms, Experimental; Organ Size; Rats; Rats, Wistar

1998
Assessment of induced rat mammary tumour response to chemotherapy using the apparent diffusion coefficient of tissue water as determined by diffusion-weighted 1H-NMR spectroscopy in vivo.
    Magma (New York, N.Y.), 1999, Volume: 8, Issue:1

    Topics: Animals; Antimetabolites, Antineoplastic; Carcinogens; Diffusion; Evaluation Studies as Topic; Female; Fluorouracil; Magnetic Resonance Spectroscopy; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Wistar; Water

1999
Chemoprevention of cancer of the upper respiratory tract of the Syrian golden hamster by aerosol administration of difluoromethylornithine and 5-fluorouracil.
    Cancer research, 2004, Apr-01, Volume: 64, Issue:7

    Topics: Administration, Inhalation; Aerosols; Animals; Anticarcinogenic Agents; Carcinogens; Carcinoma, Squamous Cell; Cricetinae; Disease Models, Animal; Eflornithine; Fluorouracil; Laryngeal Neoplasms; Lung Neoplasms; Male; Mesocricetus; Methylnitrosourea; Pharyngeal Neoplasms

2004
Induced mutation spectra at the upp locus in Salmonella typhimurium: response of the target gene in the FU assay to mechanistically different mutagens.
    Mutation research, 2005, Oct-15, Volume: 578, Issue:1-2

    Topics: Aminacrine; Benzo(a)pyrene; Drug Resistance, Microbial; Fluorouracil; Frameshift Mutation; Genes, Bacterial; Hydrogen Peroxide; Methyl Methanesulfonate; Methylnitrosourea; Mutagenicity Tests; Mutagens; Mutation; Nitrogen Mustard Compounds; Pentosyltransferases; Salmonella typhimurium

2005
Protective role of connexin 32 in steady-state hematopoiesis, regeneration state, and leukemogenesis.
    Experimental biology and medicine (Maywood, N.J.), 2007, Volume: 232, Issue:5

    Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Cell Proliferation; Connexins; Female; Flow Cytometry; Fluorouracil; Gap Junction beta-1 Protein; Gene Expression Profiling; Genotype; Hematopoiesis; Hematopoietic Stem Cells; Immunohistochemistry; Immunosuppressive Agents; Leukemia; Male; Methylnitrosourea; Mice; Mice, Inbred C57BL; Mice, Knockout; Regeneration; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spleen

2007
Levels of miRNA and Hormones in Thoracic Duct Lymph in Rats with Experimental Breast Cancer Induced by N-Methyl-N-Nitrosourea.
    Bulletin of experimental biology and medicine, 2017, Volume: 162, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinogens; Cyclophosphamide; Estradiol; Female; Fluorouracil; Follicle Stimulating Hormone; Luteinizing Hormone; Lymph; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methotrexate; Methylnitrosourea; MicroRNAs; Prolactin; Rats; Rats, Wistar; Thoracic Duct; Thyroglobulin

2017
The Thymus in Experimental Mammary Carcinogenesis and Polychemotherapy.
    Bulletin of experimental biology and medicine, 2017, Volume: 162, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinogenesis; Carcinogens; Cell Transformation, Neoplastic; Cyclophosphamide; Epithelial Cells; Female; Fluorouracil; Injections, Intraperitoneal; Lymphocytes; Macrophages; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Methotrexate; Methylnitrosourea; Rats, Wistar; Thymus Gland; Thymus Neoplasms

2017
Anterior Mediastinal Lymph Nodes in Chemically Induced Breast Cancer.
    Bulletin of experimental biology and medicine, 2017, Volume: 164, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinogens; Cell Proliferation; Cyclophosphamide; Female; Fluorouracil; Injections, Subcutaneous; Lymph Nodes; Lymphatic Metastasis; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mediastinum; Methotrexate; Methylnitrosourea; Plasma Cells; Rats; Rats, Wistar; T-Lymphocytes

2017
Effect of Neoadjuvant and Adjuvant Therapy of Experimental Breast Cancer on the Structure of Mesenteric Lymph Nodes.
    Bulletin of experimental biology and medicine, 2018, Volume: 166, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Female; Fluorouracil; Lymph Nodes; Lymphocyte Subsets; Macrophages; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mast Cells; Mesentery; Methotrexate; Methylnitrosourea; Neoadjuvant Therapy; Neutrophils; Rats; Rats, Wistar

2018
Morphological Study of Mesenteric Lymph Nodes in Rats with Experimental Breast Cancer Treated with Fragmented Double-Stranded DNA.
    Bulletin of experimental biology and medicine, 2020, Volume: 168, Issue:5

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; DNA; DNA Fragmentation; Female; Fluorouracil; Humans; Lymph Nodes; Lymphatic Metastasis; Mammary Neoplasms, Experimental; Mastectomy; Mesentery; Methotrexate; Methylnitrosourea; Rats; Rats, Wistar; Treatment Outcome

2020