Page last updated: 2024-08-21

methylnitrosourea and bromodeoxyuridine

methylnitrosourea has been researched along with bromodeoxyuridine in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19909 (37.50)18.7374
1990's8 (33.33)18.2507
2000's5 (20.83)29.6817
2010's2 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fujiwara, Y1
Deluca, JG; Hoppe, H; Penman, BW; Thilly, WG1
Khalizev, AE; Petrova, ON; Shapiro, NI1
Anisimov, VN; Osipova, GIu1
Kleihues, P; Ludeke, BI; Lutz, WK; Meier, I; Ohgaki, H; Schlatter, C1
Borzelleca, JF; Carchman, RA; Charles, JL; Condie, LW; Jacobson-Kram, D1
Herrera, RJ; Luckett, DC; Mukherjee, AB1
Denman, AM; Doré, CJ; Palmer, RG; Smith-Burchnell, CA1
Booth, JA; Ockey, CH; Saffhill, R1
Cohn, SM; Dresler, SL; Krawisz, BR; Lieberman, MW1
Bayer, U; Cheng, SJ; Chouroulinkov, I; Stahl, KW1
Kallio, M; Lähdetie, J1
Anisimov, VN1
Fukushima, S; Kurata, Y; Mizoguchi, M; Montesano, R; Naito, H; Shibata, MA; Tsuda, H; Wild, CP1
Anisimov, VN; Buzard, GS; Calvert, RJ; Rice, JM1
González-Beltrán, F; Morales-Ramírez, P1
Archer, MC; Korkola, JE; Wood, GA1
Ikeno, T; Ishida, K; Katsuyama, T; Kawasaki, S; Maruta, F; Murakami, M; Ota, H; Sugiyama, A; Tatematsu, M1
Conneely, OM; Gay, J; Hilsenbeck, SG; Medina, D; O'Malley, BW; Sivaraman, L; Zhong, L1
Bosland, MC; Condon, MS; Narayanan, BA; Narayanan, NK; Reddy, BS1
Bishop, SM; Clarke, AR; Court, H; Dudley, S; Liskay, RM; Sansom, OJ1
Kachi, S; Kaneko, H; Nakamura, M; Nishiguchi, KM; Terasaki, H1
Murasaki, T; Nakanishi, M; Ogawa, K; Shirai, T; Sugiura, S1
Hisano, S; Kato, S; Koriyama, Y; Ogai, K; Sugitani, K1

Other Studies

24 other study(ies) available for methylnitrosourea and bromodeoxyuridine

ArticleYear
Postreplication repair of alkylation damage to DNA of mammalian cells in culture.
    Cancer research, 1975, Volume: 35, Issue:10

    Topics: Alkylation; Bromodeoxyuridine; Caffeine; DNA; DNA Repair; DNA Replication; Dose-Response Relationship, Drug; Drug Synergism; L Cells; Mesylates; Methyl Methanesulfonate; Methylnitrosourea; Molecular Weight; Nitrosourea Compounds; Photolysis; Thymidine; Ultraviolet Rays

1975
Phenotypic lag and mutation to 6-thioguanine resistance in diploid human lymphoblasts.
    Mutation research, 1978, Volume: 50, Issue:1

    Topics: Bromodeoxyuridine; Cells, Cultured; Cytological Techniques; Drug Resistance; Humans; Lymphocyte Activation; Lymphocytes; Methylnitronitrosoguanidine; Methylnitrosourea; Mutation; Nitrogen Mustard Compounds; Phenotype; Thioguanine; Time Factors

1978
[A further study of the mutation process in Chinese hamster cells in vitro].
    Genetika, 1975, Volume: 10, Issue:7

    Topics: Animals; Bromodeoxyuridine; Clone Cells; Cricetinae; Drug Resistance; Freezing; Mercaptopurine; Methylnitrosourea; Mutagens; Mutation; Time Factors

1975
[Carcinogenesis induced by the neonatal administration of 5-bromo-2'-deoxyuridine and subsequent exposure to N-nitrosomethylurea in rats].
    Voprosy onkologii, 1992, Volume: 38, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Bromodeoxyuridine; Drug Interactions; Female; Life Tables; Male; Methylnitrosourea; Neoplasms, Experimental; Rats; Sex Factors

1992
DNA methylation in the digestive tract of F344 rats during chronic exposure to N-methyl-N-nitrosourea.
    Journal of cancer research and clinical oncology, 1991, Volume: 117, Issue:1

    Topics: Administration, Oral; Animals; Bromodeoxyuridine; Cell Division; Deoxyguanosine; Digestive System; DNA; DNA Damage; Epithelium; Esophagus; Hyperplasia; Immunoblotting; Male; Methylation; Methylnitrosourea; Purines; Rats; Rats, Inbred F344

1991
The kinetics of in vivo sister chromatid exchange induction in mouse bone marrow cells by ethylnitrosourea and methylnitrosourea.
    Toxicology and applied pharmacology, 1986, Jun-15, Volume: 84, Issue:1

    Topics: Animals; Bone Marrow; Bromodeoxyuridine; DNA Repair; Dose-Response Relationship, Drug; Ethylnitrosourea; Kinetics; Male; Methylnitrosourea; Mice; Mice, Inbred Strains; Regression Analysis; Sister Chromatid Exchange

1986
Spontaneous and induced sister-chromatid exchanges in cultured mosquito cells.
    Cytobios, 1986, Volume: 46, Issue:186-187

    Topics: Aedes; Animals; Bromodeoxyuridine; Cell Line; Dose-Response Relationship, Drug; Ethyl Methanesulfonate; Ethylnitrosourea; Methyl Methanesulfonate; Methylnitrosourea; Mutagens; Sister Chromatid Exchange; Species Specificity

1986
Sensitivity of lymphocytes from patients with systemic lupus erythematosus to the induction of sister chromatid exchanges by alkylating agents and bromodeoxyuridine.
    Annals of the rheumatic diseases, 1987, Volume: 46, Issue:2

    Topics: Alkylating Agents; Bromodeoxyuridine; Chlorambucil; Humans; In Vitro Techniques; Lupus Erythematosus, Systemic; Lymphocytes; Methyl Methanesulfonate; Methylnitrosourea; Sister Chromatid Exchange

1987
The effect of cell proliferation, bromodeoxyuridine concentration, and deoxynucleoside triphosphate pools on sister chromatid exchange induction.
    Basic life sciences, 1984, Volume: 29 Pt A

    Topics: Animals; Bromodeoxyuridine; Cell Division; Cell Line; Cricetinae; Cricetulus; Deoxyribonucleotides; Female; Fibroblasts; Methyl Methanesulfonate; Methylnitrosourea; Ovary; Sister Chromatid Exchange

1984
Induction of replicative DNA synthesis in quiescent human fibroblasts by DNA damaging agents.
    Proceedings of the National Academy of Sciences of the United States of America, 1984, Volume: 81, Issue:15

    Topics: Acetoxyacetylaminofluorene; Bromodeoxyuridine; Cell Cycle; Cells, Cultured; DNA Repair; DNA Replication; Humans; Methylnitrosourea; Ultraviolet Rays; Xeroderma Pigmentosum

1984
Genotoxicity of N-methyl-N-nitrosourea in the presence of amphiphilic membrane-active compounds.
    Toxicology and applied pharmacology, 1981, Volume: 60, Issue:1

    Topics: Animals; Bromodeoxyuridine; Castor Oil; Cells, Cultured; Cricetinae; Drug Interactions; Glycerol; Membranes; Methylnitrosourea; Mutagens; Nitrosourea Compounds; Sister Chromatid Exchange

1981
Early G1 in the male rat meiotic cell cycle is hypersensitive to N-methyl-N-nitrosourea-induced micronucleus formation.
    Mutagenesis, 1995, Volume: 10, Issue:4

    Topics: Animals; Bromodeoxyuridine; Carcinogens; Cell Cycle; Drug Implants; Epithelial Cells; Epithelium; G1 Phase; Male; Meiosis; Methylnitrosourea; Micronuclei, Chromosome-Defective; Micronucleus Tests; Microscopy, Fluorescence; Rats; Rats, Sprague-Dawley; S Phase; Spermatids; Spermatocytes; Spermatozoa; Testis

1995
Effect of aging and interval between primary and secondary treatment in carcinogenesis induced by neonatal exposure to 5-bromodeoxyuridine and subsequent administration of N-nitrosomethylurea in rats.
    Mutation research, 1995, Volume: 316, Issue:4

    Topics: Aging; Animals; Animals, Newborn; Bromodeoxyuridine; Carcinogens; Cocarcinogenesis; Female; Male; Methylnitrosourea; Pregnancy; Rats

1995
Influence of aging on multi-organ carcinogenesis in rats induced by N-methyl-N-nitrosourea.
    Japanese journal of cancer research : Gann, 1993, Volume: 84, Issue:2

    Topics: Adenocarcinoma; Aging; Animals; Bromodeoxyuridine; Deoxyguanosine; DNA; Intestinal Neoplasms; Lymphoma; Male; Methylnitrosourea; Neoplasms, Experimental; Rats; Rats, Inbred F344; Splenic Neoplasms; Thymus Neoplasms; Tongue Neoplasms

1993
K-ras codon 12 and 61 point mutations in bromodeoxyuridine- and N-nitrosomethylurea-induced rat renal mesenchymal tumors.
    Cancer letters, 1996, Dec-03, Volume: 109, Issue:1-2

    Topics: Adenine; Animals; Bromodeoxyuridine; Carcinogens; Codon; Female; Genes, ras; Guanine; Kidney Neoplasms; Male; Mesenchymoma; Methylnitrosourea; Neoplasms, Experimental; Point Mutation; Polymerase Chain Reaction; Rats

1996
In vivo repair during G1 of DNA lesions eliciting sister chromatid exchanges induced by methylnitrosourea or ethylnitrosourea in BrdU substituted or unsubstituted DNA in murine salivary gland cells.
    Mutation research, 1999, Apr-06, Volume: 425, Issue:2

    Topics: Animals; Bromodeoxyuridine; Cell Division; DNA Damage; DNA Repair; Drug Synergism; Ethylnitrosourea; G1 Phase; Isoproterenol; Male; Methylnitrosourea; Mice; Mice, Inbred BALB C; Mutagens; Salivary Glands; Sister Chromatid Exchange

1999
Cyclin D1 expression during rat mammary tumor development and its potential role in the resistance of the Copenhagen rat.
    Breast cancer research : BCR, 1999, Volume: 1, Issue:1

    Topics: Animals; Bromodeoxyuridine; Carcinoma in Situ; Carcinoma, Ductal, Breast; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p16; Female; Immunohistochemistry; Mammary Neoplasms, Experimental; Methylnitrosourea; Precancerous Conditions; Rats; Rats, Inbred WF

1999
Timing of N-methyl-N-nitrosourea administration affects gastric carcinogenesis in Mongolian gerbils infected with Helicobacter pylori.
    Cancer letters, 2000, Nov-10, Volume: 160, Issue:1

    Topics: Adenocarcinoma; Alkylating Agents; Animals; Bromodeoxyuridine; Gastric Mucosa; Gastritis; Gerbillinae; Helicobacter Infections; Helicobacter pylori; Intestines; Metaplasia; Methylnitrosourea; Stomach Neoplasms; Time Factors

2000
Early exposure of the rat mammary gland to estrogen and progesterone blocks co-localization of estrogen receptor expression and proliferation.
    The Journal of endocrinology, 2001, Volume: 171, Issue:1

    Topics: Animals; Breast Neoplasms; Bromodeoxyuridine; Carcinogens; Cell Division; Estradiol; Female; Fluorescent Antibody Technique; Mammary Glands, Animal; Methylnitrosourea; Progesterone; Rats; Rats, Inbred WF; Receptors, Estrogen

2001
Suppression of N-methyl-N-nitrosourea/testosterone-induced rat prostate cancer growth by celecoxib: effects on cyclooxygenase-2, cell cycle regulation, and apoptosis mechanism(s).
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Aug-15, Volume: 9, Issue:9

    Topics: Alkylating Agents; Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Bromodeoxyuridine; Carcinogens; Celecoxib; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cell Survival; Coloring Agents; Cyclin D; Cyclin E; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Cyclooxygenase 2; DNA; Dose-Response Relationship, Drug; Down-Regulation; Flow Cytometry; Immunohistochemistry; Isoenzymes; Male; Methylnitrosourea; Microscopy, Fluorescence; Models, Biological; Prostaglandin-Endoperoxide Synthases; Prostatic Neoplasms; Pyrazoles; Rats; Retinoblastoma Protein; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Time Factors; Tumor Suppressor Proteins

2003
Apoptosis and mutation in the murine small intestine: loss of Mlh1- and Pms2-dependent apoptosis leads to increased mutation in vivo.
    DNA repair, 2003, Sep-18, Volume: 2, Issue:9

    Topics: Adaptor Proteins, Signal Transducing; Adenosine Triphosphatases; Animals; Apoptosis; Base Pair Mismatch; Bromodeoxyuridine; Carrier Proteins; Dacarbazine; DNA Repair; DNA Repair Enzymes; DNA-Binding Proteins; Dose-Response Relationship, Drug; Intestine, Small; Male; Methylnitrosourea; Mice; Mice, Mutant Strains; Mismatch Repair Endonuclease PMS2; Mitotic Index; Mutation; MutL Protein Homolog 1; MutS Homolog 2 Protein; Neoplasm Proteins; Nuclear Proteins; Proto-Oncogene Proteins; Temozolomide; Time Factors

2003
Identification of photoreceptor precursors in the pars plana during ocular development and after retinal injury.
    Investigative ophthalmology & visual science, 2008, Volume: 49, Issue:1

    Topics: Animals; Bromodeoxyuridine; Cell Differentiation; Ciliary Body; Eye; Eye Proteins; Fluorescent Antibody Technique, Indirect; Homeodomain Proteins; Methylnitrosourea; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Paired Box Transcription Factors; PAX6 Transcription Factor; Photoreceptor Cells, Vertebrate; Pigment Epithelium of Eye; Recoverin; Repressor Proteins; Retinal Degeneration; Rhodopsin; Stem Cells

2008
Organ differences in the impact of p27(kip1) deficiency on carcinogenesis induced by N-methyl-N-nitrosourea.
    Journal of applied toxicology : JAT, 2013, Volume: 33, Issue:6

    Topics: Adenocarcinoma; Alkylating Agents; Animals; Antimetabolites; Body Weight; Bromodeoxyuridine; Carcinogens; Carcinoma, Squamous Cell; Cyclin-Dependent Kinase Inhibitor p27; Genotype; Immunohistochemistry; Lymphoma; Male; Methylnitrosourea; Mice; Mice, Knockout; Neoplasms; Organ Size; Organ Specificity

2013
Cell Fate of Müller Cells During Photoreceptor Regeneration in an N-Methyl-N-nitrosourea-Induced Retinal Degeneration Model of Zebrafish.
    Advances in experimental medicine and biology, 2016, Volume: 854

    Topics: Animals; Bromodeoxyuridine; Cell Proliferation; Disease Models, Animal; Ependymoglial Cells; Female; Immunohistochemistry; Male; Methylnitrosourea; Photoreceptor Cells, Vertebrate; Proliferating Cell Nuclear Antigen; Regeneration; Retinal Degeneration; Zebrafish

2016