methylmalonyl-coenzyme a has been researched along with sirolimus in 3 studies
| Studies (methylmalonyl-coenzyme a) | Trials (methylmalonyl-coenzyme a) | Recent Studies (post-2010) (methylmalonyl-coenzyme a) | Studies (sirolimus) | Trials (sirolimus) | Recent Studies (post-2010) (sirolimus) |
|---|---|---|---|---|---|
| 145 | 0 | 35 | 20,711 | 2,368 | 11,516 |
| Protein | Taxonomy | methylmalonyl-coenzyme a (IC50) | sirolimus (IC50) |
|---|---|---|---|
| Bile salt export pump | Homo sapiens (human) | 10 | |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | 1.25 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 2 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 2 | |
| Peptidyl-prolyl cis-trans isomerase FKBP1A | Mus musculus (house mouse) | 0.001 | |
| Cytochrome P450 2C19 | Homo sapiens (human) | 4 | |
| Serine/threonine-protein kinase mTOR | Homo sapiens (human) | 0.0897 | |
| Peptidyl-prolyl cis-trans isomerase FKBP1A | Homo sapiens (human) | 0.0042 | |
| Regulatory-associated protein of mTOR | Homo sapiens (human) | 0.225 | |
| Target of rapamycin complex subunit LST8 | Homo sapiens (human) | 0.225 | |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | 1.9 | |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | 1.1 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cane, DE; Fu, H; Khosla, C; Lau, J | 1 |
| Cane, DE; Khosla, C; Lau, J; Liou, GF | 1 |
| Ban, YH; Han, AR; Jung, WS; Kim, E; Kim, EJ; Park, JW; Park, SR; Yoo, YJ; Yoon, YJ | 1 |
3 other study(ies) available for methylmalonyl-coenzyme a and sirolimus
| Article | Year |
|---|---|
Dissecting the role of acyltransferase domains of modular polyketide synthases in the choice and stereochemical fate of extender units.
Topics: Acyl Coenzyme A; Acyltransferases; Amino Acid Sequence; Erythromycin; Escherichia coli; Isoenzymes; Molecular Sequence Data; Multienzyme Complexes; Plasmids; Protein Processing, Post-Translational; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sirolimus; Stereoisomerism; Streptomyces; Substrate Specificity; Thiolester Hydrolases | 1999 |
Quantitative analysis of loading and extender acyltransferases of modular polyketide synthases.
Topics: Acetyl Coenzyme A; Acyl Carrier Protein; Acyl Coenzyme A; Acyltransferases; Cysteamine; Genetic Vectors; Histidine; Kinetics; Malonyl Coenzyme A; Multienzyme Complexes; Mutagenesis, Site-Directed; Protein Structure, Tertiary; Protein Subunits; Quantitative Structure-Activity Relationship; Sirolimus; Substrate Specificity | 2003 |
A combined approach of classical mutagenesis and rational metabolic engineering improves rapamycin biosynthesis and provides insights into methylmalonyl-CoA precursor supply pathway in Streptomyces hygroscopicus ATCC 29253.
Topics: Acyl Coenzyme A; Bacterial Proteins; Biosynthetic Pathways; Gene Expression Regulation, Bacterial; Genetic Engineering; Methylmalonyl-CoA Decarboxylase; Methylmalonyl-CoA Mutase; Mutagenesis; Sirolimus; Streptomyces | 2011 |