Page last updated: 2024-09-03

methylmalonyl-coenzyme a and malonyl coenzyme a

methylmalonyl-coenzyme a has been researched along with malonyl coenzyme a in 36 studies

Compound Research Comparison

Studies
(methylmalonyl-coenzyme a)
Trials
(methylmalonyl-coenzyme a)
Recent Studies (post-2010)
(methylmalonyl-coenzyme a)
Studies
(malonyl coenzyme a)
Trials
(malonyl coenzyme a)
Recent Studies (post-2010) (malonyl coenzyme a)
1450351,1697278

Protein Interaction Comparison

ProteinTaxonomymethylmalonyl-coenzyme a (IC50)malonyl coenzyme a (IC50)
Carnitine O-palmitoyltransferase 1, muscle isoformRattus norvegicus (Norway rat)1.2

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-199021 (58.33)18.7374
1990's6 (16.67)18.2507
2000's4 (11.11)29.6817
2010's4 (11.11)24.3611
2020's1 (2.78)2.80

Authors

AuthorsStudies
Blomquist, GJ; Chase, J; Juárez, P1
Kamoun, P1
Allen, RH; Brass, EP; Ruff, LJ; Stabler, SP1
Harding, SE; Leadlay, PF; Marsh, EN1
Hull, WE; König, A; Michenfelder, M; Rétey, J; Wölfle, K1
Allen, RH; Kolhouse, JF; Stabler, SP1
McGrath, RP1
Allen, RH; Stabler, SP1
Thompson, TE; Zeikus, JG1
Balapangu, A; Kolattukudy, PE; Rogers, LM1
Dimroth, P; Hoffmann, A1
Ball, MS; Robbins, JE; Williams, SA1
Kolattukudy, PE; Rainwater, DL2
Rosenberg, LE; Willard, HF1
Hunaiti, AA; Kolattukudy, PE1
Fuller, JQ; Leadlay, PF2
Eggerer, H; Kollmann-Koch, A1
Elliot, JM; Smith, A; Wahle, KW; Williamson, IP1
Allen, RH; Copley, SD; Kovachy, RJ1
Palotie, A; Puukka, M; Ruokonen, A; Ruostesuo, J; Similä, S1
Decloedt, M; DePooter, H; Schamp, N1
Blomquist, GJ; Chu, AJ; Nelson, JH; Pomonis, JG1
Cane, DE1
Aparicio, JF; Caffrey, P; Leadlay, PF; Loughran, MS; Marsden, AF; Staunton, J1
Bauer, Z; Fuchs, G; Gad'on, N; Huber, H; Menendez, C; Stetter, KO1
Carey, PR; Hyatt , DC; Rivera, RE; Wang, YF; Yee, VC1
Carey, PR; Hall, PR; Pusztai-Carey, M; Rivera-Hainaj, RE; Yee, VC; Zheng, X; Zheng, Y1
Cane, DE; Khosla, C; Lau, J; Liou, GF1
Fuchs, G; Hügler, M; Jahn, M; Krieger, RS1
Jia, Y; Zhong, JJ1
Awakawa, T; Horinouchi, S; Katsuyama, Y; Masuda, S; Ohnishi, Y; Otsutomo, K; Ren, S; Sugai, Y1
Cane, DE; Dunn, BJ; Khosla, C; Robbins, T; Watts, KR1
Bardou, F; Bazet Lyonnet, B; Diacovich, L; Gago, G; Gramajo, H; Lemassu, A; Quémard, A; Spina, L1
Kick, BJ; Lohman, JR; Stunkard, LM1

Reviews

1 review(s) available for methylmalonyl-coenzyme a and malonyl coenzyme a

ArticleYear
Valine is a precursor of propionyl-CoA.
    Trends in biochemical sciences, 1992, Volume: 17, Issue:5

    Topics: Acyl Coenzyme A; Animals; Humans; Malonyl Coenzyme A; Valine

1992

Other Studies

35 other study(ies) available for methylmalonyl-coenzyme a and malonyl coenzyme a

ArticleYear
A microsomal fatty acid synthetase from the integument of Blattella germanica synthesizes methyl-branched fatty acids, precursors to hydrocarbon and contact sex pheromone.
    Archives of biochemistry and biophysics, 1992, Volume: 293, Issue:2

    Topics: Acyl Coenzyme A; Animals; Cockroaches; Fatty Acid Synthases; Fatty Acids; Female; Ketones; Malonyl Coenzyme A; Microsomes; Sex Attractants

1992
Effect of hydroxycobalamin[c-lactam] on propionate and carnitine metabolism in the rat.
    The Biochemical journal, 1990, Mar-15, Volume: 266, Issue:3

    Topics: Acyl Coenzyme A; Animals; Carnitine; Hydroxocobalamin; Lactams; Liver; Male; Malonates; Malonyl Coenzyme A; Propionates; Rats; Vitamin B 12 Deficiency

1990
Subunit interactions in Propionibacterium shermanii methylmalonyl-CoA mutase studied by analytical ultracentrifugation.
    The Biochemical journal, 1989, Jun-01, Volume: 260, Issue:2

    Topics: Acyl Coenzyme A; Ammonium Sulfate; Isomerases; Malonyl Coenzyme A; Methylmalonyl-CoA Mutase; Molecular Conformation; Molecular Weight; Propionibacterium; Ultracentrifugation

1989
On the mechanism of action of methylmalonyl-CoA mutase. Change of the steric course on isotope substitution.
    European journal of biochemistry, 1986, May-02, Volume: 156, Issue:3

    Topics: Acyl Coenzyme A; Catalysis; Cobamides; Deuterium; Isomerases; Isotope Labeling; Kinetics; Magnetic Resonance Spectroscopy; Malonyl Coenzyme A; Methylmalonyl-CoA Mutase; Stereoisomerism; Substrate Specificity; Tritium

1986
L-methylmalonyl-CoA mutase from human placenta.
    Methods in enzymology, 1988, Volume: 166

    Topics: Acyl Coenzyme A; Carbon Radioisotopes; Chromatography, Affinity; Chromatography, DEAE-Cellulose; Female; Humans; Indicators and Reagents; Isomerases; Kinetics; Macromolecular Substances; Malonyl Coenzyme A; Methylmalonyl-CoA Mutase; Molecular Weight; Placenta; Pregnancy; Radioisotope Dilution Technique

1988
Unusual case of metabolic acidosis.
    Critical care medicine, 1989, Volume: 17, Issue:1

    Topics: Acidosis, Lactic; Acyl Coenzyme A; Adult; Humans; Male; Malonyl Coenzyme A

1989
DL-methylmalonyl-CoA racemase from rat liver.
    Methods in enzymology, 1988, Volume: 166

    Topics: Acyl Coenzyme A; Animals; Chromatography, Affinity; Chromatography, Gel; Chromatography, Ion Exchange; Isomerases; Kinetics; Liver; Macromolecular Substances; Malonyl Coenzyme A; Molecular Weight; Racemases and Epimerases; Radioisotope Dilution Technique; Rats; Tritium

1988
Regulation of carbon and electron flow in Propionispira arboris: relationship of catabolic enzyme levels to carbon substrates fermented during propionate formation via the methylmalonyl coenzyme A pathway.
    Journal of bacteriology, 1988, Volume: 170, Issue:9

    Topics: Acyl Coenzyme A; Bacteria; Carbon; Electron Transport; Fermentation; Fumarates; Glucose; Glycolysis; Lactates; Magnetic Resonance Spectroscopy; Malonyl Coenzyme A; Oxidoreductases; Propionates; Pyruvates; Trees

1988
Synthesis of methyl-branched fatty acids from methylmalonyl-CoA by fatty acid synthase from both the liver and the harderian gland of the guinea pig.
    Archives of biochemistry and biophysics, 1987, May-15, Volume: 255, Issue:1

    Topics: Acyl Coenzyme A; Animals; Chromatography, Gel; Fatty Acid Synthases; Fatty Acids; Guinea Pigs; Harderian Gland; Lacrimal Apparatus; Liver; Male; Malonyl Coenzyme A; Methylation

1987
Stereochemistry of the methylmalonyl-CoA decarboxylation reaction.
    FEBS letters, 1987, Aug-10, Volume: 220, Issue:1

    Topics: Acyl Coenzyme A; Biotin; Carboxy-Lyases; Catalysis; Decarboxylation; Malonyl Coenzyme A; Methylmalonyl-CoA Decarboxylase; Veillonella

1987
Synthesis and NMR spectra of 13C-labeled coenzyme A esters.
    Analytical biochemistry, 1986, Aug-15, Volume: 157, Issue:1

    Topics: Acyl Coenzyme A; Carbon Isotopes; Magnetic Resonance Spectroscopy; Malonyl Coenzyme A

1986
Fatty acid biosynthesis in Mycobacterium tuberculosis var. bovis Bacillus Calmette-Guérin. Purification and characterization of a novel fatty acid synthase, mycocerosic acid synthase, which elongates n-fatty acyl-CoA with methylmalonyl-CoA.
    The Journal of biological chemistry, 1985, Jan-10, Volume: 260, Issue:1

    Topics: Acyl Coenzyme A; Acyltransferases; Amino Acids; Carbon Radioisotopes; Chromatography, Gas; Fatty Acids; Kinetics; Malonyl Coenzyme A; Molecular Weight; Mycobacterium bovis; Structure-Activity Relationship

1985
Interactions of methylmalonyl CoA mutase from normal human fibroblasts with adenosylcobalamin and methylmalonyl CoA: evidence for non-equivalent active sites.
    Archives of biochemistry and biophysics, 1980, Volume: 200, Issue:1

    Topics: Acyl Coenzyme A; Binding Sites; Cells, Cultured; Cobamides; Drug Stability; Fibroblasts; Hot Temperature; Humans; Isomerases; Kinetics; Macromolecular Substances; Malonyl Coenzyme A; Methylmalonyl-CoA Mutase; Skin

1980
Source of methylmalonyl-coenzyme A for erythromycin synthesis: methylmalonyl-coenzyme A mutase from Streptomyces erythreus.
    Antimicrobial agents and chemotherapy, 1984, Volume: 25, Issue:2

    Topics: Acyl Coenzyme A; Bacterial Proteins; Chromatography, DEAE-Cellulose; Erythromycin; Hydrogen-Ion Concentration; Isomerases; Kinetics; Malonyl Coenzyme A; Methylmalonyl-CoA Mutase; Streptomyces; Vitamin B 12

1984
Proton transfer in methylmalonyl-CoA epimerase from Propionibacterium shermanii. Studies with specifically tritiated (2R)-methylmalonyl-CoA as substrate.
    The Biochemical journal, 1983, Sep-01, Volume: 213, Issue:3

    Topics: Acyl Coenzyme A; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Isomerases; Kinetics; Malonyl Coenzyme A; Propionibacterium; Protons; Racemases and Epimerases; Tritium

1983
Proton transfer in methylmalonyl-CoA epimerase from Propionibacterium shermanii. The reaction of (2R)-methylmalonyl-CoA in tritiated water.
    The Biochemical journal, 1983, Sep-01, Volume: 213, Issue:3

    Topics: Acyl Coenzyme A; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Isomerases; Malonyl Coenzyme A; Propionibacterium; Protons; Racemases and Epimerases; Tritium; Water

1983
Synthesis of mycocerosic acids from methylmalonyl coenzyme A by cell-free extracts of Mycobacterium tuberculosis var. bovis BCG.
    The Journal of biological chemistry, 1983, Mar-10, Volume: 258, Issue:5

    Topics: Acyl Coenzyme A; Fatty Acids; Gas Chromatography-Mass Spectrometry; Kinetics; Malonyl Coenzyme A; Mycobacterium tuberculosis; Structure-Activity Relationship

1983
Nicotinic acid metabolism. Dimethylmaleate hydratase.
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1984, Volume: 365, Issue:8

    Topics: Acyl Coenzyme A; Clostridium; Enzyme Activation; Ferrous Compounds; Hydro-Lyases; Kinetics; Malonyl Coenzyme A; Molecular Weight; Niacin; Propionates; Selenious Acid; Selenium; Stereoisomerism; Substrate Specificity; Sulfhydryl Reagents

1984
Inhibition in vitro of lipogenic enzymes from bovine (Bos taurus) mammary tissue by methylmalonyl-coenzyme A and coenzyme A.
    Comparative biochemistry and physiology. B, Comparative biochemistry, 1984, Volume: 78, Issue:1

    Topics: Acyl Coenzyme A; Adenosine Triphosphate; Animals; Cattle; Coenzyme A; Dicarboxylic Acids; Enzyme Activation; Fatty Acid Synthases; Female; Kinetics; Malonates; Malonyl Coenzyme A; Mammary Glands, Animal

1984
Recognition, isolation, and characterization of rat liver D-methylmalonyl coenzyme A hydrolase.
    The Journal of biological chemistry, 1983, Sep-25, Volume: 258, Issue:18

    Topics: Acyl Coenzyme A; Amino Acids; Animals; Circular Dichroism; Coenzyme A; Isomerism; Kinetics; Liver; Male; Malonates; Malonyl Coenzyme A; Molecular Weight; Rats; Rats, Inbred Strains; Thiolester Hydrolases

1983
[Methylmalonic aciduria].
    Duodecim; laaketieteellinen aikakauskirja, 1982, Volume: 98, Issue:18

    Topics: Acyl Coenzyme A; Gas Chromatography-Mass Spectrometry; Humans; Infant; Male; Malonates; Malonyl Coenzyme A; Metabolism, Inborn Errors

1982
Composition and variability of the branched-chain fatty acid fraction in the milk of goats and cows.
    Lipids, 1981, Volume: 16, Issue:5

    Topics: Acyl Coenzyme A; Animals; Cattle; Chemical Phenomena; Chemistry; Fatty Acids; Female; Gas Chromatography-Mass Spectrometry; Goats; Malonyl Coenzyme A; Milk; Propionates

1981
Incorporation of [2,3-13C]succinate into methyl-branched alkanes in a termite.
    Archives of biochemistry and biophysics, 1980, Oct-15, Volume: 204, Issue:2

    Topics: Acyl Coenzyme A; Alkanes; Animals; Chemical Phenomena; Chemistry; Insecta; Magnetic Resonance Spectroscopy; Malonyl Coenzyme A; Succinates

1980
Polyketide biosynthesis: molecular recognition or genetic programming?
    Science (New York, N.Y.), 1994, Jan-21, Volume: 263, Issue:5145

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Anthraquinones; Anti-Bacterial Agents; Cell-Free System; Erythromycin; Malonyl Coenzyme A; Multienzyme Complexes; Naphthacenes; Streptomyces

1994
Stereospecific acyl transfers on the erythromycin-producing polyketide synthase.
    Science (New York, N.Y.), 1994, Jan-21, Volume: 263, Issue:5145

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Erythromycin; Malonyl Coenzyme A; Molecular Conformation; Multienzyme Complexes; Racemases and Epimerases; Saccharopolyspora; Stereoisomerism; Substrate Specificity

1994
Presence of acetyl coenzyme A (CoA) carboxylase and propionyl-CoA carboxylase in autotrophic Crenarchaeota and indication for operation of a 3-hydroxypropionate cycle in autotrophic carbon fixation.
    Journal of bacteriology, 1999, Volume: 181, Issue:4

    Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Acyl Coenzyme A; Aerobiosis; Biotin; Carbon Dioxide; Carboxy-Lyases; Chlorobi; Crenarchaeota; Genes, Archaeal; Lactic Acid; Malonyl Coenzyme A; Methylmalonyl-CoA Decarboxylase; Peptides; Sequence Homology; Succinic Acid; Sulfolobaceae

1999
Crystallization and preliminary X-ray analysis of the 12S central subunit of transcarboxylase from Propionibacterium shermanii.
    Acta crystallographica. Section D, Biological crystallography, 2001, Volume: 57, Issue:Pt 2

    Topics: Acyl Coenzyme A; Carboxyl and Carbamoyl Transferases; Crystallization; Crystallography, X-Ray; Malonyl Coenzyme A; Molecular Weight; Propionibacterium; Protein Subunits; Recombinant Proteins; Sequence Deletion; Synchrotrons

2001
Substrate binding induces a cooperative conformational change in the 12S subunit of transcarboxylase: Raman crystallographic evidence.
    Biochemistry, 2002, Sep-03, Volume: 41, Issue:35

    Topics: Acyl Coenzyme A; Binding Sites; Carboxyl and Carbamoyl Transferases; Crystallization; Crystallography, X-Ray; Malonyl Coenzyme A; Propionibacterium; Protein Conformation; Protein Subunits; Spectrum Analysis, Raman; Substrate Specificity

2002
Quantitative analysis of loading and extender acyltransferases of modular polyketide synthases.
    Biochemistry, 2003, Jan-14, Volume: 42, Issue:1

    Topics: Acetyl Coenzyme A; Acyl Carrier Protein; Acyl Coenzyme A; Acyltransferases; Cysteamine; Genetic Vectors; Histidine; Kinetics; Malonyl Coenzyme A; Multienzyme Complexes; Mutagenesis, Site-Directed; Protein Structure, Tertiary; Protein Subunits; Quantitative Structure-Activity Relationship; Sirolimus; Substrate Specificity

2003
Characterization of acetyl-CoA/propionyl-CoA carboxylase in Metallosphaera sedula. Carboxylating enzyme in the 3-hydroxypropionate cycle for autotrophic carbon fixation.
    European journal of biochemistry, 2003, Volume: 270, Issue:4

    Topics: Acetyl Coenzyme A; Acetyl-CoA Carboxylase; Acyl Coenzyme A; Biotin; Blotting, Southern; Carbon Dioxide; Carbon-Nitrogen Ligases; Carboxy-Lyases; Catalysis; Cloning, Molecular; Escherichia coli; Fatty Acid Desaturases; Hot Temperature; Malonyl Coenzyme A; Methylmalonyl-CoA Decarboxylase; Oxidoreductases; Plasmids; Protein Subunits; Sulfolobaceae

2003
Enhanced production of ansamitocin P-3 by addition of Mg2+ in fermentation of Actinosynnema pretiosum.
    Bioresource technology, 2011, Volume: 102, Issue:21

    Topics: Actinomycetales; Acyl Coenzyme A; Extracellular Space; Fermentation; Intracellular Space; Ions; Magnesium; Malonyl Coenzyme A; Maytansine; Metals; Time Factors

2011
4-Hydroxy-3-methyl-6-(1-methyl-2-oxoalkyl)pyran-2-one synthesis by a type III polyketide synthase from Rhodospirillum centenum.
    Chembiochem : a European journal of chemical biology, 2013, May-27, Volume: 14, Issue:8

    Topics: Acyl Coenzyme A; Acyltransferases; Genetic Loci; Malonyl Coenzyme A; Pyrans; Rhodospirillum centenum; Substrate Specificity

2013
Comparative analysis of the substrate specificity of trans- versus cis-acyltransferases of assembly line polyketide synthases.
    Biochemistry, 2014, Jun-17, Volume: 53, Issue:23

    Topics: Acyl Coenzyme A; Acyltransferases; Anti-Bacterial Agents; Bacterial Proteins; Biocatalysis; Catalytic Domain; Macrolides; Malonyl Coenzyme A; Models, Molecular; Mutant Proteins; Oxazoles; Peptide Fragments; Polyketide Synthases; Polyketides; Protein Engineering; Protein Interaction Domains and Motifs; Protein Structure, Quaternary; Protein Subunits; Pyridones; Recombinant Fusion Proteins; Stereoisomerism; Substrate Specificity

2014
Functional reconstitution of the Mycobacterium tuberculosis long-chain acyl-CoA carboxylase from multiple acyl-CoA subunits.
    The FEBS journal, 2017, Volume: 284, Issue:7

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Bacterial Proteins; Carbon-Carbon Ligases; Cloning, Molecular; Enzyme Assays; Escherichia coli; Gene Expression; Kinetics; Malonyl Coenzyme A; Mycobacterium tuberculosis; Mycolic Acids; Polyketide Synthases; Protein Engineering; Protein Subunits; Recombinant Proteins; Substrate Specificity

2017
Structures of LnmK, a Bifunctional Acyltransferase/Decarboxylase, with Substrate Analogues Reveal the Basis for Selectivity and Stereospecificity.
    Biochemistry, 2021, 02-09, Volume: 60, Issue:5

    Topics: Acyl Carrier Protein; Acyl Coenzyme A; Acyltransferases; Carbon-Carbon Ligases; Carboxy-Lyases; Catalysis; Catalytic Domain; Malonyl Coenzyme A; Streptomyces; Streptomyces coelicolor; Substrate Specificity

2021