methyllycaconitine has been researched along with pnu-282987 in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (15.79) | 29.6817 |
| 2010's | 14 (73.68) | 24.3611 |
| 2020's | 2 (10.53) | 2.80 |
| Authors | Studies |
|---|---|
| El Kouhen, R; Gopalakrishnan, M; Hu, M; Li, J; Puttfarcken, PS; Schurdak, ME | 1 |
| Anderson, DJ; Bertrand, D; Bunnelle, W; Du, J; Gopalakrishnan, M; Marguerat, A; Surber, B; Surowy, C; Tribollet, E | 1 |
| Boyle, DL; Firestein, GS; Pavlov, VA; Tracey, KJ; Waldburger, JM | 1 |
| del Barrio, L; Egea, J; García, AG; López, MG; Parada, E; Romero, A | 1 |
| Bugert, P; Klüter, H; Schedel, A; Schloss, P; Thornton, S | 1 |
| Saeed Dar, M; Taslim, N | 1 |
| Andreotti, N; Brégeon, F; Delpierre, S; Jammes, Y; Lepidi, H; Ravailhe, S; Roch, A; Steinberg, JG; Xeridat, F | 1 |
| Anjum, N; Carlès, M; Giffard, R; Iles, KE; Lafargue, M; Pittet, JF; Serve, E; Xiong, X; Xu, L | 1 |
| Bhyrapuneni, G; Kandikere, V; Komarneni, P; Muddana, N; Nirogi, R; Saralaya, R | 1 |
| Calixto, JB; Cola, M; Costa, R; Manjavachi, MN; Motta, EM | 1 |
| Pandya, AA; Yakel, JL | 1 |
| Gergalova, G; Komisarenko, S; Lykhmus, O; Skok, M | 1 |
| Colmena, I; de Pascual, R; Gandía, L; Lagrota-Candido, J; Leite, PE; Nanclares, C; Quirico-Santos, T; Santos, WC | 1 |
| de Moura, FB; McMahon, LR | 1 |
| Cheng, Y; Li, X; Wang, R; Xu, Y | 1 |
| Cecon, E; Chollet, AM; Dam, J; Danober, L; Delagrange, P; Gautier, C; Jockers, R; Luka, M | 1 |
| Feng, DF; Li, HJ; Pan, YB; Sun, ZL; Xu, MH | 1 |
| Bao, J; Dai, J; Han, X; He, Y; Hu, G; Li, B; Ni, J; Niu, M; Shen, S; Wang, X; Wen, L; Wu, J; Wu, Z; Ye, X | 1 |
| Chu, Z; Luo, S; Shan, H; Tan, Y; Zhangsun, D; Zhu, X | 1 |
19 other study(ies) available for methyllycaconitine and pnu-282987
| Article | Year |
|---|---|
High content screen microscopy analysis of A beta 1-42-induced neurite outgrowth reduction in rat primary cortical neurons: neuroprotective effects of alpha 7 neuronal nicotinic acetylcholine receptor ligands.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Amyloid beta-Peptides; Animals; Animals, Newborn; Benzamides; Bridged Bicyclo Compounds; Cell Count; Cells, Cultured; Cerebral Cortex; Cholinergic Agents; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Memantine; Neurites; Neurons; Nicotinic Antagonists; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic | 2007 |
[3H]A-585539 [(1S,4S)-2,2-dimethyl-5-(6-phenylpyridazin-3-yl)-5-aza-2-azoniabicyclo[2.2.1]heptane], a novel high-affinity alpha7 neuronal nicotinic receptor agonist: radioligand binding characterization to rat and human brain.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Benzamides; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Bungarotoxins; Cell Line; Humans; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pyridazines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Spiro Compounds | 2008 |
Acetylcholine regulation of synoviocyte cytokine expression by the alpha7 nicotinic receptor.
Topics: Acetylcholine; Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Arthritis, Rheumatoid; Benzamides; Blotting, Western; Bridged Bicyclo Compounds; Cells, Cultured; Cytokines; Humans; Immunohistochemistry; Interleukin-6; NF-kappa B; Osteoarthritis; Polymerase Chain Reaction; Proteins; Receptors, Nicotinic; RNA, Messenger; Synovial Membrane | 2008 |
Poststress treatment with PNU282987 can rescue SH-SY5Y cells undergoing apoptosis via α7 nicotinic receptors linked to a Jak2/Akt/HO-1 signaling pathway.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Apoptosis; Benzamides; Bridged Bicyclo Compounds; Cells, Cultured; Cytoprotection; Drug Evaluation, Preclinical; Heme Oxygenase-1; Humans; Janus Kinase 2; Nicotinic Agonists; Nicotinic Antagonists; Oncogene Protein v-akt; Oxidative Stress; Reactive Oxygen Species; Receptors, Nicotinic; Signal Transduction; Time Factors | 2010 |
Human platelets express functional alpha7-nicotinic acetylcholine receptors.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Benzamides; Blood Platelets; Bridged Bicyclo Compounds; Bungarotoxins; Calcium; Cell Line; Humans; Megakaryocytes; Nicotinic Agonists; Nicotinic Antagonists; Platelet Activation; Platelet Aggregation; Receptors, Fibrinogen; Receptors, Nicotinic; RNA, Messenger | 2011 |
The role of nicotinic acetylcholine receptor (nAChR) α7 subtype in the functional interaction between nicotine and ethanol in mouse cerebellum.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Ataxia; Benzamides; Bridged Bicyclo Compounds; Cerebellum; Dose-Response Relationship, Drug; Ethanol; Infusions, Intraventricular; Male; Mice; Nicotine; Receptors, Nicotinic | 2011 |
Activation of nicotinic cholinergic receptors prevents ventilator-induced lung injury in rats.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Anesthesia; Animals; Benzamides; Bridged Bicyclo Compounds; Enzyme-Linked Immunosorbent Assay; Interleukin-6; Lung; Male; Nicotinic Agonists; Nicotinic Antagonists; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Substance P; Ventilator-Induced Lung Injury | 2011 |
Stroke-induced activation of the α7 nicotinic receptor increases Pseudomonas aeruginosa lung injury.
Topics: Aconitine; Adrenergic beta-Antagonists; alpha7 Nicotinic Acetylcholine Receptor; Animals; Benzamides; Bridged Bicyclo Compounds; Cell Line; Disease Models, Animal; Immune Tolerance; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neutrophils; Nicotinic Agonists; Nicotinic Antagonists; Pneumonia, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections; Pulmonary Edema; Receptors, Nicotinic; Signal Transduction | 2012 |
Methyllycaconitine: a non-radiolabeled ligand for mapping α7 neuronal nicotinic acetylcholine receptors - in vivo target localization and biodistribution in rat brain.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Benzamides; Benzofurans; Binding Sites; Brain; Brain Chemistry; Bridged Bicyclo Compounds; Dose-Response Relationship, Drug; Ligands; Male; Nicotinic Antagonists; Quinuclidines; Rats; Rats, Wistar; Receptors, Nicotinic | 2012 |
Activation of the alpha-7 nicotinic acetylcholine receptor (α7 nAchR) reverses referred mechanical hyperalgesia induced by colonic inflammation in mice.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Analgesics; Animals; Behavior, Animal; Benzamides; Bridged Bicyclo Compounds; Colitis; Dose-Response Relationship, Drug; Drug Antagonism; Hyperalgesia; Male; Mice; Mice, Inbred Strains; Molecular Targeted Therapy; Nerve Tissue Proteins; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pain Threshold; Pain, Referred; Random Allocation; Receptors, Nicotinic | 2012 |
Activation of the α7 nicotinic ACh receptor induces anxiogenic effects in rats which is blocked by a 5-HT₁a receptor antagonist.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Anxiety; Behavior, Animal; Benzamides; Bridged Bicyclo Compounds; Drug Interactions; Isoxazoles; Learning; Male; Memory Disorders; Nicotinic Agonists; Nicotinic Antagonists; Phenylurea Compounds; Piperazines; Rats; Scopolamine; Serotonin 5-HT1 Receptor Antagonists | 2013 |
α7 nicotinic acetylcholine receptors control cytochrome c release from isolated mitochondria through kinase-mediated pathways.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Androstadienes; Animals; Benzamides; Bridged Bicyclo Compounds; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cytochromes c; Male; Mice; Mice, Inbred C57BL; Mitochondria, Liver; Nicotinic Agonists; Nicotinic Antagonists; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; src-Family Kinases; Superoxides; Wortmannin | 2014 |
Selective activation of α7 nicotinic acetylcholine receptor (nAChRα7) inhibits muscular degeneration in mdx dystrophic mice.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Benzamides; Bridged Bicyclo Compounds; Bupivacaine; Cell Death; Disease Models, Animal; Dose-Response Relationship, Drug; Inflammation; Male; Mice, Inbred C57BL; Mice, Inbred mdx; Mice, Knockout; Muscle, Skeletal; Muscular Dystrophy, Animal; Muscular Dystrophy, Duchenne; Necrosis; Nicotinic Agonists; Nicotinic Antagonists; Regeneration | 2014 |
The contribution of α4β2 and non-α4β2 nicotinic acetylcholine receptors to the discriminative stimulus effects of nicotine and varenicline in mice.
Topics: Aconitine; Alkaloids; alpha7 Nicotinic Acetylcholine Receptor; Animals; Azocines; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cocaine; Dihydro-beta-Erythroidine; Discrimination, Psychological; Dopamine Uptake Inhibitors; Hypnotics and Sedatives; Ibogaine; Male; Mecamylamine; Mice; Mice, Inbred C57BL; Midazolam; Nerve Tissue Proteins; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pyridines; Quinolizines; Receptors, Nicotinic; Varenicline | 2017 |
α7 Nicotinic acetylcholine receptor contributes to the alleviation of lung ischemia-reperfusion injury by transient receptor potential vanilloid type 1 stimulation.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Apoptosis; Benzamides; Bridged Bicyclo Compounds; Capsaicin; Disease Models, Animal; Down-Regulation; Humans; Lung; Lung Injury; Male; Mice; Mice, Knockout; Reperfusion Injury; Treatment Outcome; TRPV Cation Channels | 2018 |
Quantitative assessment of oligomeric amyloid β peptide binding to α7 nicotinic receptor.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Amyloid beta-Peptides; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bungarotoxins; HEK293 Cells; Humans; Isoxazoles; Ligands; Phenylurea Compounds; Pyridines; Pyridinium Compounds; Quinuclidines; Thiophenes | 2019 |
Effect of α7nAChR on learning and memory dysfunction in a rat model of diffuse axonal injury.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Benzamides; Bridged Bicyclo Compounds; Cognitive Dysfunction; Diffuse Axonal Injury; Disease Models, Animal; Learning; Male; Maze Learning; Memory; Rats; Rats, Sprague-Dawley | 2019 |
Activation of α7nACh receptor protects against acute pancreatitis through enhancing TFEB-regulated autophagy.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Autophagy; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Benzamides; Bridged Bicyclo Compounds; Ceruletide; Ethanol; Fatty Acids, Monounsaturated; Injections, Intraperitoneal; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; Pancreatitis; Signal Transduction | 2020 |
Inflammation Regulation via an Agonist and Antagonists of α7 Nicotinic Acetylcholine Receptors in RAW264.7 Macrophages.
Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Anti-Inflammatory Agents; Benzamides; Bridged Bicyclo Compounds; Cell Survival; Conotoxins; Cytokines; Gene Expression Regulation; Interleukin-6; Lipopolysaccharides; Mice; Nicotinic Agonists; Nicotinic Antagonists; RAW 264.7 Cells | 2022 |