Page last updated: 2024-08-26

methyllycaconitine and pnu 120596

methyllycaconitine has been researched along with pnu 120596 in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's6 (85.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bowlby, MR; Dunlop, J; Friis, S; Mathes, C; Sunesen, M1
Gusev, AG; Uteshev, VV1
Pandya, AA; Yakel, JL1
Chatzidaki, A; Dage, J; Fouillet, A; Li, J; Millar, NS; Sher, E; Ursu, D1
Alzarea, S; Rahman, S1
Bo, J; Gu, X; Hou, B; Huo, W; Lei, Y; Liu, Y; Liu, Z; Ma, Z; Mao, Y; Sun, R; Sun, Y; Zhang, W; Zhang, Y; Zhang, Z1
Cecon, E; Chollet, AM; Dam, J; Danober, L; Delagrange, P; Gautier, C; Jockers, R; Luka, M1

Other Studies

7 other study(ies) available for methyllycaconitine and pnu 120596

ArticleYear
Characterization of compounds on nicotinic acetylcholine receptor alpha7 channels using higher throughput electrophysiology.
    Journal of neuroscience methods, 2009, Feb-15, Volume: 177, Issue:1

    Topics: Acetylcholine; Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Area Under Curve; Cell Line, Transformed; Cholinergic Agents; Dose-Response Relationship, Drug; Inhibitory Concentration 50; Isoxazoles; Membrane Potentials; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Phenylurea Compounds; Rats; Receptors, Nicotinic

2009
Physiological concentrations of choline activate native alpha7-containing nicotinic acetylcholine receptors in the presence of PNU-120596 [1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)-urea].
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 332, Issue:2

    Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Calcium; Choline; Drug Synergism; Female; Hypothalamic Area, Lateral; Isoxazoles; Male; Membrane Potentials; Neurons; Nicotinic Agonists; Nicotinic Antagonists; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic

2010
Activation of the α7 nicotinic ACh receptor induces anxiogenic effects in rats which is blocked by a 5-HT₁a receptor antagonist.
    Neuropharmacology, 2013, Volume: 70

    Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Anxiety; Behavior, Animal; Benzamides; Bridged Bicyclo Compounds; Drug Interactions; Isoxazoles; Learning; Male; Memory Disorders; Nicotinic Agonists; Nicotinic Antagonists; Phenylurea Compounds; Piperazines; Rats; Scopolamine; Serotonin 5-HT1 Receptor Antagonists

2013
Pharmacological Characterisation of Nicotinic Acetylcholine Receptors Expressed in Human iPSC-Derived Neurons.
    PloS one, 2015, Volume: 10, Issue:4

    Topics: Aconitine; Cells, Cultured; Gene Expression Regulation; Humans; Induced Pluripotent Stem Cells; Isoxazoles; Neurons; Phenylurea Compounds; Receptors, Nicotinic; Single-Cell Analysis

2015
Effects of alpha-7 nicotinic allosteric modulator PNU 120596 on depressive-like behavior after lipopolysaccharide administration in mice.
    Progress in neuro-psychopharmacology & biological psychiatry, 2018, 08-30, Volume: 86

    Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Antidepressive Agents; Calcium-Binding Proteins; Cholinergic Agents; Depressive Disorder; Disease Models, Animal; Hippocampus; Inflammation; Isoxazoles; Lipopolysaccharides; Male; Mice, Inbred C57BL; Microfilament Proteins; Microglia; Motor Activity; Phenylurea Compounds; Prefrontal Cortex

2018
Perioperative activation of spinal α7 nAChR promotes recovery from preoperative stress-induced prolongation of postsurgical pain.
    Brain, behavior, and immunity, 2019, Volume: 79

    Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Anti-Inflammatory Agents; Anxiety; Astrocytes; Bridged Bicyclo Compounds, Heterocyclic; Chronic Pain; Cytokines; Hyperalgesia; Isoxazoles; Male; Microglia; Nicotinic Agonists; Phenylurea Compounds; Preoperative Period; Quinuclidines; Rats; Rats, Sprague-Dawley; Spinal Cord; Spine; Stress, Psychological

2019
Quantitative assessment of oligomeric amyloid β peptide binding to α7 nicotinic receptor.
    British journal of pharmacology, 2019, Volume: 176, Issue:18

    Topics: Aconitine; alpha7 Nicotinic Acetylcholine Receptor; Amyloid beta-Peptides; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bungarotoxins; HEK293 Cells; Humans; Isoxazoles; Ligands; Phenylurea Compounds; Pyridines; Pyridinium Compounds; Quinuclidines; Thiophenes

2019